6-Pentyl-α-pyrone (6PP), a natural product with a number of bioactivies, has been synthesized from furfural in a five steps route. The key step is the epoxidation of 2-furyl-pentylcarbinol (3) with NBS in a mixed sol...6-Pentyl-α-pyrone (6PP), a natural product with a number of bioactivies, has been synthesized from furfural in a five steps route. The key step is the epoxidation of 2-furyl-pentylcarbinol (3) with NBS in a mixed solvent system THF and H2O(4: 1). The overall yield is 34%.展开更多
文摘6-Pentyl-α-pyrone (6PP), a natural product with a number of bioactivies, has been synthesized from furfural in a five steps route. The key step is the epoxidation of 2-furyl-pentylcarbinol (3) with NBS in a mixed solvent system THF and H2O(4: 1). The overall yield is 34%.