目的:评价半夏白术天麻汤治疗血管性头痛的临床疗效。方法:检索EMBASE、PUBMED、MEDLINE、AMED、CINAHL、Cochrane图书馆、中国知网数据库、重庆维普中文科技期刊数据库、中国生物医学文献数据库、万方数据库和中国中医药期刊文献数据库...目的:评价半夏白术天麻汤治疗血管性头痛的临床疗效。方法:检索EMBASE、PUBMED、MEDLINE、AMED、CINAHL、Cochrane图书馆、中国知网数据库、重庆维普中文科技期刊数据库、中国生物医学文献数据库、万方数据库和中国中医药期刊文献数据库,筛选从建库至2015年5月1日的半夏白术天麻汤治疗血管性头痛的随机对照试验研究。应用Cochrane评价员手册进行偏倚风险评价,Jadad评分法进行质量评价,应用Rev Man 5.3软件进行Meta分析。结果:符合纳入标准的文献共3篇。Meta分析结果:半夏白术天麻汤治疗血管性头痛治疗组与对照组比较,临床疗效总有效率比值比(odds ratio,OR)为6.25,95%可信区间(confidence interval,CI)为[2.28,17.16],差异有统计学意义(P=0.0004);显效率OR为4.81,95%CI为[2.51,9.22],差异有统计学意义(P<0.00001)。纳入研究未有不良反应报道。结论:半夏白术天麻汤治疗血管性头痛有较好临床疗效,但由于本系统评价纳入研究的样本总体质量较低,研究的数量和样本量均较小,尚需要更多高质量、多中心、大样本、严格设计的随机对照试验深入研究。展开更多
Senile dementia is a chronic progressivedisease of mental deterioration. It correspondsto“idiocy”,“melancholia”or“epilepsy”inTCM. The pathogeneses, and symptoms andsigns of this disease are very complicated,
Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFan...Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFang,Chinese Biomedical Databases,PubMed,and EMbase were searched by computer,and randomized controlled trials that met the inclusion criteria were retrieved.The Cochrane bias risk assessment tool was used to evaluate the quality of the included studies.RevMan 5.3 software was used to conduct meta quantitative analysis of the included studies.Results A total of 19 studies were included,with a total sample size of 1,635 cases,821 cases in the treatment group and 814 cases in the control group.The results of meta-analysis showed that(1)the clinical effective rate of the single use of Banxia Baizhu Tianma decoction or western medicine combined with Banxia Baizhu Tianma decoction in treating migraine was better than that of western medicine alone(p<0.001);(2)the improvement in cumulative number and days of vertigo in the treatment of migraine with Banxia Baizhu Tianma decoction was observed in the control group(p<0.001).TSA results showed that Z-curve passed both the traditional threshold and Trial sequential analysis(TSA)threshold.In terms of adverse reactions,55 cases were reported,including 12 cases in the treatment group and 43 cases in the control group,and no serious adverse reactions were found.Conclusion Compared with the single use of western medicine therapy,the combination of Banxia Baizhu Tianma decoction and western medicine or the single use of Banxia Baizhu Tianma decoction could better improve the effective rate and showed good safety and low incidence of adverse reactions.展开更多
文摘目的:评价半夏白术天麻汤治疗血管性头痛的临床疗效。方法:检索EMBASE、PUBMED、MEDLINE、AMED、CINAHL、Cochrane图书馆、中国知网数据库、重庆维普中文科技期刊数据库、中国生物医学文献数据库、万方数据库和中国中医药期刊文献数据库,筛选从建库至2015年5月1日的半夏白术天麻汤治疗血管性头痛的随机对照试验研究。应用Cochrane评价员手册进行偏倚风险评价,Jadad评分法进行质量评价,应用Rev Man 5.3软件进行Meta分析。结果:符合纳入标准的文献共3篇。Meta分析结果:半夏白术天麻汤治疗血管性头痛治疗组与对照组比较,临床疗效总有效率比值比(odds ratio,OR)为6.25,95%可信区间(confidence interval,CI)为[2.28,17.16],差异有统计学意义(P=0.0004);显效率OR为4.81,95%CI为[2.51,9.22],差异有统计学意义(P<0.00001)。纳入研究未有不良反应报道。结论:半夏白术天麻汤治疗血管性头痛有较好临床疗效,但由于本系统评价纳入研究的样本总体质量较低,研究的数量和样本量均较小,尚需要更多高质量、多中心、大样本、严格设计的随机对照试验深入研究。
文摘Senile dementia is a chronic progressivedisease of mental deterioration. It correspondsto“idiocy”,“melancholia”or“epilepsy”inTCM. The pathogeneses, and symptoms andsigns of this disease are very complicated,
基金Shenzhen“Three Top Medical and Health Projects”(SZZYSM 202111011)Shenzhen Science and Technology Planning Project(JCYJ20180302173504891,JCYJ20190812161807600).
文摘Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFang,Chinese Biomedical Databases,PubMed,and EMbase were searched by computer,and randomized controlled trials that met the inclusion criteria were retrieved.The Cochrane bias risk assessment tool was used to evaluate the quality of the included studies.RevMan 5.3 software was used to conduct meta quantitative analysis of the included studies.Results A total of 19 studies were included,with a total sample size of 1,635 cases,821 cases in the treatment group and 814 cases in the control group.The results of meta-analysis showed that(1)the clinical effective rate of the single use of Banxia Baizhu Tianma decoction or western medicine combined with Banxia Baizhu Tianma decoction in treating migraine was better than that of western medicine alone(p<0.001);(2)the improvement in cumulative number and days of vertigo in the treatment of migraine with Banxia Baizhu Tianma decoction was observed in the control group(p<0.001).TSA results showed that Z-curve passed both the traditional threshold and Trial sequential analysis(TSA)threshold.In terms of adverse reactions,55 cases were reported,including 12 cases in the treatment group and 43 cases in the control group,and no serious adverse reactions were found.Conclusion Compared with the single use of western medicine therapy,the combination of Banxia Baizhu Tianma decoction and western medicine or the single use of Banxia Baizhu Tianma decoction could better improve the effective rate and showed good safety and low incidence of adverse reactions.
