目的探討超聲心動圖(經胸及經食管)對經導管二尖瓣夾合術治療重度二尖瓣反流的操作指導和療效評估的價值。方法2015年12月~2016年12月於本院使用Mitra Clip系統在TEE引導下行經導管二尖瓣夾合術的有症狀重度二尖瓣反流患者7例,總結經食...目的探討超聲心動圖(經胸及經食管)對經導管二尖瓣夾合術治療重度二尖瓣反流的操作指導和療效評估的價值。方法2015年12月~2016年12月於本院使用Mitra Clip系統在TEE引導下行經導管二尖瓣夾合術的有症狀重度二尖瓣反流患者7例,總結經食管超聲心動圖指導術中操作的經驗,分析7例患者術前及術後1週臨床表現、經胸超聲心動圖變化以及術後1月併發症隨訪。結果7例患者均順利完成手術,5例患者置入1個MitraClip,2例患者置入2個MitraClip,術後即刻二尖瓣反流量均較術前下降1~3級。術後1週複查超聲心動圖示急性手術成功率為71.4%(定義為出院前二尖瓣反流≤2級);術後1週二尖瓣反流束長度由術前(3.88±0.354)級降至術後(2.13±1.36)級(P=0.006),二尖瓣反流面積由(13.74±8.57)c m^(2)下降至(6.55±4.46)c m2(P=0.043),患者N Y H A心功能分級由術前平均(3.71±0.49)級降至術後(2.29±0.76)級(P=0.003),其差異均具有統計學意義。術後1週主動脈平均壓、肺動脈收縮壓、左心室舒張末期內徑、左心房內徑與術前比較無統計學差異。術後1月隨訪,除1例患者因金屬夾移位引起腱索斷裂、二尖瓣反流加重、心力衰竭導致死亡之外,其餘患者無併發症發生。結論超聲心動圖可指導經導管二尖瓣夾合術治療重度二尖瓣反流的術中操作,評估術後療效;同時,經導管二尖瓣夾合術對經過選擇的重度二尖瓣反流患者安全、有效,中長期效果需待進一步隨訪。展开更多
The effects of inclusions on microstructure, mechanical property, corrosion behavior of Mg-10Gd-3Y （GW103K） alloys by unrefining, MgO ceramic filtering and JDMJ flux refining were investigated, respectively. The res...The effects of inclusions on microstructure, mechanical property, corrosion behavior of Mg-10Gd-3Y （GW103K） alloys by unrefining, MgO ceramic filtering and JDMJ flux refining were investigated, respectively. The results indicate that with decreasing significantly the number and size grade of inclusions for the alloy refined with JDMJ flux, tensile strength and elongation increase; however, the yield strength is less than that of the alloy refined with MgO ceramic filter and unrefined alloy. With the decrease of the inclusions contents, the corrosion rate of the alloys quickly vary from 2.419 mg/（cm 2 ·d） to 1.265 mg/（cm 2 ·d）. After inclusion content is reduced to 0.385%, the corrosion rate has almost no changes. Finally, the relationship between the volume fraction of inclusions and service properties of GW103K alloy under different conditions are established quantitatively.展开更多
文摘目的探討超聲心動圖(經胸及經食管)對經導管二尖瓣夾合術治療重度二尖瓣反流的操作指導和療效評估的價值。方法2015年12月~2016年12月於本院使用Mitra Clip系統在TEE引導下行經導管二尖瓣夾合術的有症狀重度二尖瓣反流患者7例,總結經食管超聲心動圖指導術中操作的經驗,分析7例患者術前及術後1週臨床表現、經胸超聲心動圖變化以及術後1月併發症隨訪。結果7例患者均順利完成手術,5例患者置入1個MitraClip,2例患者置入2個MitraClip,術後即刻二尖瓣反流量均較術前下降1~3級。術後1週複查超聲心動圖示急性手術成功率為71.4%(定義為出院前二尖瓣反流≤2級);術後1週二尖瓣反流束長度由術前(3.88±0.354)級降至術後(2.13±1.36)級(P=0.006),二尖瓣反流面積由(13.74±8.57)c m^(2)下降至(6.55±4.46)c m2(P=0.043),患者N Y H A心功能分級由術前平均(3.71±0.49)級降至術後(2.29±0.76)級(P=0.003),其差異均具有統計學意義。術後1週主動脈平均壓、肺動脈收縮壓、左心室舒張末期內徑、左心房內徑與術前比較無統計學差異。術後1月隨訪,除1例患者因金屬夾移位引起腱索斷裂、二尖瓣反流加重、心力衰竭導致死亡之外,其餘患者無併發症發生。結論超聲心動圖可指導經導管二尖瓣夾合術治療重度二尖瓣反流的術中操作,評估術後療效;同時,經導管二尖瓣夾合術對經過選擇的重度二尖瓣反流患者安全、有效,中長期效果需待進一步隨訪。
基金Project(2007CB613701)supported by the National Basic Research Program of ChinaProject(20100470125)by National Science Foundation for Post-doctoral Scientists of ChinaProject(2009021028)supported by Science and Technique Foundation for Young Scholars of Shanxi Province
文摘The effects of inclusions on microstructure, mechanical property, corrosion behavior of Mg-10Gd-3Y （GW103K） alloys by unrefining, MgO ceramic filtering and JDMJ flux refining were investigated, respectively. The results indicate that with decreasing significantly the number and size grade of inclusions for the alloy refined with JDMJ flux, tensile strength and elongation increase; however, the yield strength is less than that of the alloy refined with MgO ceramic filter and unrefined alloy. With the decrease of the inclusions contents, the corrosion rate of the alloys quickly vary from 2.419 mg/（cm 2 ·d） to 1.265 mg/（cm 2 ·d）. After inclusion content is reduced to 0.385%, the corrosion rate has almost no changes. Finally, the relationship between the volume fraction of inclusions and service properties of GW103K alloy under different conditions are established quantitatively.
