冬奇子口服液延缓皮肤衰老的实验研究

目的探讨冬奇子口服液对D-半乳糖所致衰老小鼠皮肤组织衰老程度的影响及其延缓衰老的作用。方法选用昆明种小鼠50只,雌雄各半,随机分为冬奇子口服液低、中、高剂量组(剂量分别为0.1,0.2,0.3 ml/20 g),模型组和正常对照组;除正常对照组注射等量生理盐水外,其他组均采用颈背部皮下注射D-半乳糖(剂量为0.1 ml/20 g)法复制亚急性衰老模型,连续42 d。各给药组造模的同时皮肤涂布给药,42 d后取各组小鼠背部皮肤检测含水量、羟脯氨酸(HYP)含量及超氧化物歧化酶(SOD)活力和丙二醛(MDA)含量。结果冬奇子口服液可保持皮肤组织水分,明显提高亚急性衰老小鼠皮肤中SOD活性以及HYP含量,并使皮肤MDA含量降低。结论冬奇子口服液具有延缓皮肤衰老作用。

冬奇子口服液总黄酮含量测定及稳定性研究

目的：以麦冬、五味子等药材为主药的冬奇子口服液,对其进行质量标准和稳定性的研究。方法：采用紫外分光光度法对冬奇子口服液中的成分——黄酮进行含量测定;建立了该制剂中黄酮的含量测定方法。对冬奇子口服液做影响因素实验,测定其在高温、高湿和光照条件下的稳定性。结果：用紫外分光光度计测定黄酮的含量,结果：黄酮的线性范围6～32μg/m L,相关系数r=0.9993,加样平均回收率98.35%（n=5）,RSD=1.35%,样品中黄酮的平均含量为20.95%;稳定性实验结果表明,口服液在高温、高湿和光照下稳定。结论：冬奇子口服液质量标准科学可控,制剂稳定。

冬奇子口服液抗衰老的实验研究

目的:观察冬奇子口服液的抗衰老作用。方法:冬奇子口服液连续灌胃14d,进行小鼠免疫器官重量实验。另取小鼠50只,建立亚急性衰老模型,连续灌胃40d,检测血清SOD活性和MDA含量。结果:冬奇子口服液能增加正常小鼠免疫器官重量,采用D-半乳糖皮下注射40d后,检测到小鼠血清中的SOD活性明显下降和MDA含量明显升高(P<0.05),说明成功制备出衰老模型。灌胃冬奇子口服液后,检测到小鼠血清中的SOD活性显著升高和MDA含量显著下降(P<0.01)。结论:冬奇子口服液对延缓小鼠、D-半乳糖致衰方面有一定功效。

冬奇子口服液的研制及质量标准的研究

目的:优选枸杞、五味子、麦冬最佳提取工艺,制成"冬奇子"口服液。并对其中的主要化学成分进行定性、定量分析,制定出口服液的质量标准。方法:采用超声波-水提法,对药物有效成分进行提取分离,用薄层层析和纸层析等对有效成分进行了分析。结果:制成"冬奇子"口服液,颜色为深棕色、澄明,无刺激性。结论:由超声波-水提法所制得的"冬奇子"口服液的制备工艺和质量标准科学合理。方法可行,制剂质量稳定。

冬奇子口服液的研制及质量标准的探讨

目的 :以枸杞子、五味子、麦冬等为主药研制“冬奇子”口服液。并对其中的化学成分进行分离分析 ,制定出口服液的质量标准。方法 :采用超声波——醇提取水沉淀法 ,对药物有效成分进行提取分离 ,用 TL C法、化学法等对有效成分进行了分析。结果 :制成“冬奇子”口服液 ,颜色橘黄、澄明 ,无刺激性。结论 :由超声波——醇提水沉法所制得的“冬奇子”口服液质量合格。标准真实、准确、可靠。

冬奇子口服液对小鼠肝损伤保护作用的研究

目的通过建立四氯化碳(CCl4)致小鼠急性肝损伤模型,观察冬奇子口服液对肝损伤的的保护作用,并初步探讨冬奇子口服液的保肝机制。方法将50只ICR小鼠随机分为5组:对照组,CCl4致肝损伤模型组,低、中、高剂量的冬奇子给药组(1、2.5、5g/kg)。各组连续给药7 d,末次给药1h后,正常组腹腔注射调和油,其余各组腹腔注射0.1%CCl4调和油溶液(10 ml/kg),18 h后测定血清丙氨基转移酶(ALT)和天门冬氨酸氨基转移酶(AST),肝组织丙二醛(MDA)和超氧化物歧化酶(SOD)的活性。结果低、中、高剂量的冬奇子给药组与肝损伤模型组比较,血清ALT分别降低16.27%(<0.05)、64.96%(<0.01)和113.77%(<0.01);血清AST分别降低33.79%(<0.05)、61.20%(<0.01)和87.31%(<0.01);肝组织MDA含量分别降低28.27%(<0.05)、65.74%(<0.01)和108.89%(<0.01);肝组织SOD活性分别增加13.82%(>0.05)、27.31%(<0.05)和40.73%(<0.05)。结论冬奇子口服液对肝损伤具有保护作用,其机制可能与减少肝组织脂质过氧反应,增强SOD的抗自由基的能力有关。

奇静脉弓在影像学的应用解剖

目的：阐明奇静脉弓周围的结构，为医学影像ＣＴ、ＭＲＩ介入放射提供解剖学依据。方法：观测成人尸体标本５０例和连续横断层标本５例。结果：①３８％奇静弓在第４—５胸椎平面跨过右主支气管上方汇入上腔静脉，此处血管外径为１０１ｃｍ±０１８ｃｍ。②７６％奇静脉弓下缘平对气管杈平面。③１００％的奇静脉弓上缘平对主动脉弓的下缘。④在奇静脉弓汇入上腔静脉平面，１００％的主动脉上隐窝和奇静脉弓淋巴结（气管前淋巴结）位于上腔静脉、奇静脉弓、主—肺动脉窗所围成的气管前间隙内。⑤１００％右迷走神经亦恒定位于奇静脉弓后份、气管和食管所围成的间隙内。结论：奇静脉弓是纵隔上部重要的结构、是识别相邻结构的重要标志，因而在解剖学和影像学上有重要的意义。

二维立方映象流域边界的结构和解析表示

本文采用函数分析法进一步研究了二雏立方映象的流域边界的结构和解析性质。构造了流域边界的解析形式,给出了流域的全部边界并发现流域边界在参量变化的情况下从光滑变到分形发生在该边界自身上。

First-Principles Study on Switching Performance and Spin Filtering Efficiency of Dimethyldihydropyrene/Cyclophanediene Single-Molecule Devices with Zigzag Graphene Nanoribbon Electrodes

Moleculardeviceswith highswitchingperformance and/or the perfect spin filtering effect have always been the pursuit with the development of molecular electronics.Hereb,yusingthe 2001.0V nonequilibrium.Green's function method in combination with the density functionaltheory,the switching performance and spin filtering properties of dimethyldihydropyrene(DHP)/cyclophanediene(CPD)photoswitchable molecule connected by carbon atomic chains(CACs)to two zigzag graphene nanoribbon electrodes have been theoretically investigated.The results show that DHP is more conductive than CPD and therefore an evident switching effect is demonstrated,and the switching ratio(RON/OFF)can reach 4.5×103.It is further revealed that the RoON/OF of DHP/CPD closely depends on the length of CACs.More specifically,the RoN/OFF values of DHP/CPD with odd-numbered CACs are larger than those with even-numbered CACs.More interestingly,a high or even perfect spin filtering effect can be obtained in these investigated DHP/CPD single-molecule devices.Our study is helpful for future design of single-molecule switches and spin filters and provides a way to optimize their performance by means of varying the length of bridging CACs.

求一个递推数列极限的几种方法

数列{an},a1=1,an+1=（1/（1+an））,n∈N.根据此数列的特点,下面给出求其极限的三种方法,供读者参考.（一）用数学归纳法证明数列{an}的奇子列与偶子列的单调性,再由单调有界数列存在极限的公理求其极限.

1992年全国高中数学联赛试题解答

我省选手最高成绩221分(满分225分),这是我省历年来高中数学联赛中最高分,更令人高兴的是马鞍山二中初三学生石伟获得了216分的好成绩。这份解答对选择题和填空题除几个有一定难度的给出详细解答外,其他仅给出答案。对解答题的解法,大部分不同于命题组提供的参考答案。对有的试题作了评注,不妥之处请读者指正。

Relationship between Phytoplankton Distribution and Environmental Factors in the Chukchi Sea

Based on the samples collected from the Chukchi Sea during the FCNARE cruise from July to August in 1999 with the ＂Xuelong＂, the research vessel of SOA, China, the relationship between the distribution characterization of phytoplankton and environmental factors was analyzed with Primer 5.2 software. The result showed that the assemblages of phytoplankton in Chukchi Sea can be divided into three ecological groups： Arctic-boreal group, distributed mostly in northeastern ice-edge where the depth is more than 2 000 m and affected directly by Arctic Ocean; Boreal group, distributed in shelf-break ice in the center water where the depth is less 100 m; Eurythermal group, mainly distributed in the south which exchanged with North Pacific water through Bering Strait. The species diversity, cell density and distribution variability of phytoplankton among stations were great different. The range of phytoplankton density among stations was 1.6 × 10^3- 90 680.2 × 10^4 cells/m^3, and the ranges of diversity index and evenness index among stations were 0.07 - 0.87 and 0.33 - 3.82, respectively. Principal components analysis （PCA） showed that temperature and salinity had made important roles in the distribution of phytoplankton in the Chukchi Sea. Furthermore, the different influences of the variant water regimes, and the extremely dynamic physical nature of the drifting pack ice （e.g. packing, breaking up and melting ） introduce short-term variability into the water conditions that no doubt affect the phytoplankton distrubition.

An Estimate of the Enumeration Function of Multiplicative Partitions

Let f(n) denote the number of multiplicative partitions of a positive intger. We prove that if n is an odd number,then f(n)≤n/15+7/5.

Weighted Boundedness for Generalized Maximal andSingular Integral Operators in Orlicz-Morrey Spaces

In this paper,the weighted boundedness for the generalised maximal and singular integral operator in Orlicz-Morrey spaces are obtained.

Odd and Even Factors with Given Properties

Let G be a graph, and g and f be integer valued functions defined on V(G) which satisfy g(x)≤f(x) and g(x)≡f(x)(mod 2) for all x∈V(G). Then a spanning subgraph F of G is called a {g,g+2,…,f} -factor if deg_F(x)∈{g(x),g(x)+2,…,f(x)} for all x∈V(G), when g(x)=1 for all x∈V(G), such a factor is called (1,f) -odd-factor. We give necessary and sufficient conditions for a graph G to have a {g,g+2,…,f} -factor and a (1,f) -odd-factor which contains an arbitrarily given edge of G, from that we derive some interesting results.

On generalized extending modules

A module Mis called generalized extending if for any submodule N of M, there is a direct summand K of M such that N≤K and KIN is singular. Any extending module and any singular module are generalized extending. Any homomorphic image of a generalized extending module is generalized extending. Any direct sum of a singular （uniform） module and a semi-simple module is generalized extending. A ring R is a right Co-H-ring if and only if all right R modules are generalized extending modules.

Strange Meson Radiative Capture on the Proton in Low Energy QCD Lagrangian

Based on our low energy QCD Lagrangian description of strange meson photoproduction off the proton and the crossing symmetry, the strange meson radiative capture on the proton, , is investigated in the quark model of baryon structure with the same input parameter, the only strong coupling constant , as that in the strange meson photoproduction off the proton , a crossing channel of the capture reaction. A good agreement on the branching ratio between the predictions and data is obtained successfully. This excellent fit indicates that our low energy QCD Lagrangian theory with only one free parameter is an advanced and unified description of strange meson photoproduction and its associated radiative capture.

Method for obtaining high-resolution velocity spectrum based on weighted similarity

Seismic wave velocity is one of the most important processing parameters of seismic data,which also determines the accuracy of imaging.The conventional method of velocity analysis involves scanning through a series of equal intervals of velocity,producing the velocity spectrum by superposing energy or similarity coefficients.In this method,however,the sensitivity of the semblance spectrum to change of velocity is weak,so the resolution is poor.In this paper,to solve the above deficiencies of conventional velocity analysis,a method for obtaining a high-resolution velocity spectrum based on weighted similarity is proposed.By introducing two weighting functions,the resolution of the similarity spectrum in time and velocity is improved.Numerical examples and real seismic data indicate that the proposed method provides a velocity spectrum with higher resolution than conventional methods and can separate cross reflectors which are aliased in conventional semblance spectrums;at the same time,the method shows good noise-resistibility.

Description of the Superdeformed Bands of Odd-Odd Nuclei in A～80 Region

Properties of the superdeformed bands of odd-odd nuclei in A ～ 80 massregion are investigated system-atically within the supersymmetry scheme including many-bodyinteractions and a perturbation possessing the SO(5) (or SU(5)) symmetry on the rotational symmetry.The obtained γ-ray energies, and the dynamical moments of inertia agree with experimental data. Itshows that this approach is quite powerful in describing odd-odd nuclei in A ～ 80 mass region.

Properties of Strange Matter in a Model with Effective lagrangian

The strange hadronic matter with nucleons, -hyperons and -hyperons is studied by using an effective nuclear model in a mean-field approximation. The density and strangeness fraction dependence of the effective baryon masses as well as the saturation properties and stabilities of the strange hadronic matter are discussed.