目的研究度洛西汀在女性慢性盆腔痛治疗中的作用。方法选取金华市中心医院和金华市妇幼保健院2021年6月至2023年6月盆腔疼痛患者126例,随机分成对照组和观察组,剔除失访及未完成治疗12例,对照组56例,观察组58例,对照组给予盆底电刺激治...目的研究度洛西汀在女性慢性盆腔痛治疗中的作用。方法选取金华市中心医院和金华市妇幼保健院2021年6月至2023年6月盆腔疼痛患者126例,随机分成对照组和观察组,剔除失访及未完成治疗12例,对照组56例,观察组58例,对照组给予盆底电刺激治疗,观察组在对照组治疗基础上应用度洛西汀,两组均治疗3个月,治疗前后应用视觉模拟评分法(Visual analogue scale,VAS)、盆底功能障碍问卷简要版-20(Pelvic floor dysfunction inventory-20,PFDI-20)、盆底器官脱垂/尿失禁性生活问卷-12(Pelvic organ prolapse-urinary incontinence sexual function questionnaire-12,PISQ-12)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)及医院焦虑抑郁量表(Hospital anxiety and depression scale,HAD)观察两组患者治疗前后病情的改善状况。结果治疗前两组VAS、PFDI-20、PISQ-12、PSQI、HAD评分比较,差异无统计学意义(P>0.05),治疗3个月分别对比VAS(观察组:1.20±0.16,对照组:1.51±0.20,P<0.05)、PFDI-20(观察组:5.69±5.4,对照组:8.95±4.27,P<0.05)、PISQ-12(观察组:40.79±3.11,对照组:30.86±5.88,P<0.05)、PSQI(观察组:7.79±1.39,对照组:10.59±1.95,P<0.05)及HAD(观察组:6.21±1.74,对照组:9.29±2.38,P<0.05),差异有统计学意义。结论度洛西汀在女性慢性盆腔痛治疗过程中有助于改善患者疼痛、焦虑、抑郁状态,提高患者生活及睡眠质量,对女性慢性盆腔痛有改善作用,同时对患者性生活质量也有明显改善作用。展开更多
OBJECTIVE: We sought to evaluate whether there are unique characteristics associated with irritable bowel syndrome (IBS)-within a population that has chronic pelvic pain. METHODS: This cross-sectional study of new ref...OBJECTIVE: We sought to evaluate whether there are unique characteristics associated with irritable bowel syndrome (IBS)-within a population that has chronic pelvic pain. METHODS: This cross-sectional study of new referral patients attending a pelvic pain clinic between 1993 and 2000 (N = 987) evaluated characteristics associated with IBS at entry to the clinic. The characteristics that we evaluated included demographic characteristics, clinical diagnoses, history of abuse, depression, pain, and prior abdominal surgeries. RESULTS: Thirty-five percent of chronic pelvic pain patients had IBS defined by Rome I criteria. Age 40 years or older (odds ratio [OR] = 1.98, 95%confidence interval [CI]: 1.27, 3.11), muscular back pain (OR = 5.37, 95%CI: 0.98, 29.29), Symptom Checklist-90 global index score in top quartile (OR = 1.77, 95%CI: 1.09, 2.86), depression (OR = 1.93, 95%CI: 124, 3.01), 6 or more pain sites (OR = 1.67, 95%CI: 1.01, 2.78), and history of adult physical abuse (OR=1.51, 95%CI: 1.01, 2.26) were associated with IBS in the final reduced multivariable model. CONCLUSION: Specific characteristics distinguish women with IBS suggesting that IBS and chronic pelvic pain are not simply manifestations of the same disorder. Our findings could help physicians attempt to effectively treat women with IBS and chronic pelvic pain. Physicians could diagnose and treat IBS in conjunction with treatment for chronic pelvic pain.展开更多
文摘目的研究度洛西汀在女性慢性盆腔痛治疗中的作用。方法选取金华市中心医院和金华市妇幼保健院2021年6月至2023年6月盆腔疼痛患者126例,随机分成对照组和观察组,剔除失访及未完成治疗12例,对照组56例,观察组58例,对照组给予盆底电刺激治疗,观察组在对照组治疗基础上应用度洛西汀,两组均治疗3个月,治疗前后应用视觉模拟评分法(Visual analogue scale,VAS)、盆底功能障碍问卷简要版-20(Pelvic floor dysfunction inventory-20,PFDI-20)、盆底器官脱垂/尿失禁性生活问卷-12(Pelvic organ prolapse-urinary incontinence sexual function questionnaire-12,PISQ-12)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)及医院焦虑抑郁量表(Hospital anxiety and depression scale,HAD)观察两组患者治疗前后病情的改善状况。结果治疗前两组VAS、PFDI-20、PISQ-12、PSQI、HAD评分比较,差异无统计学意义(P>0.05),治疗3个月分别对比VAS(观察组:1.20±0.16,对照组:1.51±0.20,P<0.05)、PFDI-20(观察组:5.69±5.4,对照组:8.95±4.27,P<0.05)、PISQ-12(观察组:40.79±3.11,对照组:30.86±5.88,P<0.05)、PSQI(观察组:7.79±1.39,对照组:10.59±1.95,P<0.05)及HAD(观察组:6.21±1.74,对照组:9.29±2.38,P<0.05),差异有统计学意义。结论度洛西汀在女性慢性盆腔痛治疗过程中有助于改善患者疼痛、焦虑、抑郁状态,提高患者生活及睡眠质量,对女性慢性盆腔痛有改善作用,同时对患者性生活质量也有明显改善作用。
文摘OBJECTIVE: We sought to evaluate whether there are unique characteristics associated with irritable bowel syndrome (IBS)-within a population that has chronic pelvic pain. METHODS: This cross-sectional study of new referral patients attending a pelvic pain clinic between 1993 and 2000 (N = 987) evaluated characteristics associated with IBS at entry to the clinic. The characteristics that we evaluated included demographic characteristics, clinical diagnoses, history of abuse, depression, pain, and prior abdominal surgeries. RESULTS: Thirty-five percent of chronic pelvic pain patients had IBS defined by Rome I criteria. Age 40 years or older (odds ratio [OR] = 1.98, 95%confidence interval [CI]: 1.27, 3.11), muscular back pain (OR = 5.37, 95%CI: 0.98, 29.29), Symptom Checklist-90 global index score in top quartile (OR = 1.77, 95%CI: 1.09, 2.86), depression (OR = 1.93, 95%CI: 124, 3.01), 6 or more pain sites (OR = 1.67, 95%CI: 1.01, 2.78), and history of adult physical abuse (OR=1.51, 95%CI: 1.01, 2.26) were associated with IBS in the final reduced multivariable model. CONCLUSION: Specific characteristics distinguish women with IBS suggesting that IBS and chronic pelvic pain are not simply manifestations of the same disorder. Our findings could help physicians attempt to effectively treat women with IBS and chronic pelvic pain. Physicians could diagnose and treat IBS in conjunction with treatment for chronic pelvic pain.
