Objective: To investigate membrane tumor necrosis factor receptor 1 protein expression level in decidua and concentration of soluble tumor necrosis factor receptor 1 in serum in women with unexplained early spontaneou...Objective: To investigate membrane tumor necrosis factor receptor 1 protein expression level in decidua and concentration of soluble tumor necrosis factor receptor 1 in serum in women with unexplained early spontaneous abortion, threatened abortion, and compare the levels with healthy pregnant women. Methods: Thirty-seven women with unexplained early spontaneous abortion, 27 women with threatened abortion, and 34 healthy pregnant women undergoing artificial abortion of pregnancy at 6 - 10 weeks of gestation were selected. Decidual samples were collected when women were undergoing artificial abortion, and blood samples were collected at the same time. The level of membrane tumor necrosis factor receptor 1 in decidua was detected by flow cytometer, and the concentration of soluble tumor necrosis factor receptor 1 in sera was measured with an enzyme-linked immunosorbent assay. Results: The percentages of membrane tumor necrosis factor receptor 1 positive decidual cells were 16.42 ± 7.10 Mean ± SD for women with unexplained early spontaneous abortion and 13. 14 ± 6.30 for healthy pregnant women ( P < 0.05). Serum concentration of soluble tumor necrosis factor receptor 1 was significantly higher in women with unexplained early spontaneous abortion than in healthy pregnant women and in women with threatened abortion, and no difference was found between healthy pregnant women and women with threatened abortion. Conclusion: Women with unexplained early spontaneous abortion present significantly higher expression of tumor necrosis factor receptor 1 than healthy pregnant women, suggesting that over-expression of tumor necrosis factor receptor 1 may contribute to the development of early spontaneous abortion.展开更多
[Purpose]To discuss the influence of PAC on female reproductive health after abortion. [Method] It selects 3020 patients of voluntarily making abortion operation in our hospital from 2011.3-2013.03, where the PAC pati...[Purpose]To discuss the influence of PAC on female reproductive health after abortion. [Method] It selects 3020 patients of voluntarily making abortion operation in our hospital from 2011.3-2013.03, where the PAC patients are 1860 cases in the system, and the non- PAC patients are 1160 cases, conducting analysis of its clinical materials. [Result]The selection rate of reliable contraception measures in PAC group is obviously higher than non-PAC group, and the difference is of statistics significance（P〈0.05）. The repeated abortion rate in PAC group is obviously lower than the control group, and the difference is of statistics significance（P〈0.05）. [Conclusion] PAC service has a positive influence on the female reproductive health, which can improve the selection rate of patients for reliable contraception measures, reducing the repeated abortion rate, which plays a positive role in protecting the patients＇ reproductive health aspect.展开更多
文摘Objective: To investigate membrane tumor necrosis factor receptor 1 protein expression level in decidua and concentration of soluble tumor necrosis factor receptor 1 in serum in women with unexplained early spontaneous abortion, threatened abortion, and compare the levels with healthy pregnant women. Methods: Thirty-seven women with unexplained early spontaneous abortion, 27 women with threatened abortion, and 34 healthy pregnant women undergoing artificial abortion of pregnancy at 6 - 10 weeks of gestation were selected. Decidual samples were collected when women were undergoing artificial abortion, and blood samples were collected at the same time. The level of membrane tumor necrosis factor receptor 1 in decidua was detected by flow cytometer, and the concentration of soluble tumor necrosis factor receptor 1 in sera was measured with an enzyme-linked immunosorbent assay. Results: The percentages of membrane tumor necrosis factor receptor 1 positive decidual cells were 16.42 ± 7.10 Mean ± SD for women with unexplained early spontaneous abortion and 13. 14 ± 6.30 for healthy pregnant women ( P < 0.05). Serum concentration of soluble tumor necrosis factor receptor 1 was significantly higher in women with unexplained early spontaneous abortion than in healthy pregnant women and in women with threatened abortion, and no difference was found between healthy pregnant women and women with threatened abortion. Conclusion: Women with unexplained early spontaneous abortion present significantly higher expression of tumor necrosis factor receptor 1 than healthy pregnant women, suggesting that over-expression of tumor necrosis factor receptor 1 may contribute to the development of early spontaneous abortion.
文摘[Purpose]To discuss the influence of PAC on female reproductive health after abortion. [Method] It selects 3020 patients of voluntarily making abortion operation in our hospital from 2011.3-2013.03, where the PAC patients are 1860 cases in the system, and the non- PAC patients are 1160 cases, conducting analysis of its clinical materials. [Result]The selection rate of reliable contraception measures in PAC group is obviously higher than non-PAC group, and the difference is of statistics significance（P〈0.05）. The repeated abortion rate in PAC group is obviously lower than the control group, and the difference is of statistics significance（P〈0.05）. [Conclusion] PAC service has a positive influence on the female reproductive health, which can improve the selection rate of patients for reliable contraception measures, reducing the repeated abortion rate, which plays a positive role in protecting the patients＇ reproductive health aspect.
