Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS ...Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS screening protocol, by vaginal swab, for a period of two years, including 1,674 asymptotic patients. Intrapartum antibiotic prophylaxis was administrated for GBS-positive women. Results. The rate of GBS carriage was 6.9% . Antibiotics were administrated for 79,3% patients with GBS-positive culture. Of these women only 39% had an interval greater than four hours between antibiotic injection and delivery. In the group of patients with positive GBS culture, no newborn was infected and only 5% were colonised. In the GBS-negative group with 1.3% of the newborns were GBS positive. Conclusion. We were surprised by our low rate of GBS carriage and the non optimal application of antibiotics during labor. We reviewed our results with all our team and a prospective evaluation has been initiated.展开更多
B族链球菌(group B streptococcus,GBS),也称无乳链球菌,是一种革兰阳性细菌,通常无症状地定植于人类消化道和女性泌尿生殖道,是其微生物群的正常组成部分。但在妊娠期,定植的GBS可上行引起泌尿系统感染、宫内感染、早产和死产等不良结...B族链球菌(group B streptococcus,GBS),也称无乳链球菌,是一种革兰阳性细菌,通常无症状地定植于人类消化道和女性泌尿生殖道,是其微生物群的正常组成部分。但在妊娠期,定植的GBS可上行引起泌尿系统感染、宫内感染、早产和死产等不良结局,在分娩期也可能通过产道过程发生垂直传播,导致新生儿早发B族链球菌感染(early-onset group B Streptococcus infection,EOGBS)。展开更多
文摘Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS screening protocol, by vaginal swab, for a period of two years, including 1,674 asymptotic patients. Intrapartum antibiotic prophylaxis was administrated for GBS-positive women. Results. The rate of GBS carriage was 6.9% . Antibiotics were administrated for 79,3% patients with GBS-positive culture. Of these women only 39% had an interval greater than four hours between antibiotic injection and delivery. In the group of patients with positive GBS culture, no newborn was infected and only 5% were colonised. In the GBS-negative group with 1.3% of the newborns were GBS positive. Conclusion. We were surprised by our low rate of GBS carriage and the non optimal application of antibiotics during labor. We reviewed our results with all our team and a prospective evaluation has been initiated.
文摘B族链球菌(group B streptococcus,GBS),也称无乳链球菌,是一种革兰阳性细菌,通常无症状地定植于人类消化道和女性泌尿生殖道,是其微生物群的正常组成部分。但在妊娠期,定植的GBS可上行引起泌尿系统感染、宫内感染、早产和死产等不良结局,在分娩期也可能通过产道过程发生垂直传播,导致新生儿早发B族链球菌感染(early-onset group B Streptococcus infection,EOGBS)。
