Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS ...Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS screening protocol, by vaginal swab, for a period of two years, including 1,674 asymptotic patients. Intrapartum antibiotic prophylaxis was administrated for GBS-positive women. Results. The rate of GBS carriage was 6.9% . Antibiotics were administrated for 79,3% patients with GBS-positive culture. Of these women only 39% had an interval greater than four hours between antibiotic injection and delivery. In the group of patients with positive GBS culture, no newborn was infected and only 5% were colonised. In the GBS-negative group with 1.3% of the newborns were GBS positive. Conclusion. We were surprised by our low rate of GBS carriage and the non optimal application of antibiotics during labor. We reviewed our results with all our team and a prospective evaluation has been initiated.展开更多
统计分析妊娠晚期孕产妇的B族链球菌(Group B streptococcus,GBS)感染情况,及其对母婴妊娠结局的影响程度。方法 本研究以2021年1月至2022年12月时段为基础开展数据统计分析工作,观察时段内入院的253例妊娠晚期孕妇为研究对象,均接受B...统计分析妊娠晚期孕产妇的B族链球菌(Group B streptococcus,GBS)感染情况,及其对母婴妊娠结局的影响程度。方法 本研究以2021年1月至2022年12月时段为基础开展数据统计分析工作,观察时段内入院的253例妊娠晚期孕妇为研究对象,均接受B族链球菌感染检验,其中阴性组145例,阳性组108例,对不同组别孕妇的凝血功能、母婴不良妊娠结局发生率进行比较分析。结果 两组孕妇的TT检验值结果,差异无统计学意义(P>0.05),而阴性组的PT、aPTT水平更高,Fbg水平更低,相较于阳性组,统计学差异明显(P<0.05);两组孕妇的早产发生率,差异无统计学意义(P>0.05),而阴性组的胎膜早破、胎儿窘迫、宫内感染等发生率更低,相较于阳性组,统计学差异明显(P<0.05);阴性组的低体重儿、新生儿窒息、新生儿肺炎、感染等发生率都相对更低,相较于阳性组,统计学差异明显(P<0.05)。结论 妊娠晚期是B族链球菌感染发生率较高的时段,需加强GBS筛查,并采取积极的干预和治疗措施,以规避不良妊娠结局风险,保证母婴安全。展开更多
文摘Objective. To evaluate our clinical practice for Group B streptococcus (GBS) screening during pregnancy and antibiotic therapy during delivery, Material and methods. We performed a retrospective evaluation of our SBS screening protocol, by vaginal swab, for a period of two years, including 1,674 asymptotic patients. Intrapartum antibiotic prophylaxis was administrated for GBS-positive women. Results. The rate of GBS carriage was 6.9% . Antibiotics were administrated for 79,3% patients with GBS-positive culture. Of these women only 39% had an interval greater than four hours between antibiotic injection and delivery. In the group of patients with positive GBS culture, no newborn was infected and only 5% were colonised. In the GBS-negative group with 1.3% of the newborns were GBS positive. Conclusion. We were surprised by our low rate of GBS carriage and the non optimal application of antibiotics during labor. We reviewed our results with all our team and a prospective evaluation has been initiated.
