在与人教版初中英语新教材(JEC)相配套的《教师教学用书》第一册p.167、第二册p.65和第三册p.43等多处出现了Play the tape for the studentsto listen这样的句子。笔者认为该句有欠妥之处,谨在此提出与编者商榷。 Michael Swan著《英...在与人教版初中英语新教材(JEC)相配套的《教师教学用书》第一册p.167、第二册p.65和第三册p.43等多处出现了Play the tape for the studentsto listen这样的句子。笔者认为该句有欠妥之处,谨在此提出与编者商榷。 Michael Swan著《英语用法指南》第552页对句末介词做了十分清楚的说明:许多动词、形容词和名词与特定的介词一起连用。当这些动词、形容词和名词用于分句或句子的末尾时,介词常跟在的后面。例如:展开更多
Objective: To investigate after intracytoplasmic sperminjection(ICSI) the paternal-derived pronuclei of zygotes with three pronuclei(3PN) for numerical-chromosome anomalies by using fluorescence in situ hybridization....Objective: To investigate after intracytoplasmic sperminjection(ICSI) the paternal-derived pronuclei of zygotes with three pronuclei(3PN) for numerical-chromosome anomalies by using fluorescence in situ hybridization. Design: A total of 211 ICSI 3PN zygotes have been analyzed for numerical-chromosome anomalies in paternally derived pronuclei and compared with the group of 82 zygotes originated during IVF. In the ICSI group, 163 zygotes were evaluated for numerical-chromosome anomalies by using DNA probes for chromosomes 18, X, and Y, and 48 zygotes, for chromosomes 21, X, and Y. In the IVF group, 68 zygotes were evaluated for numerical-chromosome anomalies by using probes for chromosomes 18, X, and Y, and 14 zygotes, by using chromosomes 21, X, and Y. Setting and Patient(s): Tripronuclear zygotes were obtained from 74 and 176 patients participating in IVF and ICSI treatment cycles at a university hospital in Switzerland. Intervention(s): To evaluate the frequency of numerical-chromosome anomalies in different populations of infertile patients, a total of 211 ICSI zygotes were divided into three groups of zygotes from men with oligozoospermia(n=124), severe oligozoosper-mia(n=53), and azoospermia(n=34). Main Outcome Measure(s): Incidence of sex-chromosome aneuploidy, diploidy, and aneuploidy for chromosomes 18 or 21. Result(s): Overall incidence of numerical-chromosome anomalies in paternal-derived pronuclei after ICSI(9.5%) was significantly higher than the rate found in paternal-derived pronuclei of IVF zygotes(1.2%). Among ICSI zygotes, sex-chromosome aneuploidy(5.2%) and diploidy(2.8%) were two dominant numerical anomalies in paternal-derived pronuclei. In contrast, aneuploidy for autosomes 18 or 21 was not significantly different when comparing ICSI with IVF zygotes. Regarding different groups of infertile patients, the highest incidence of numerical chromosome anomalies was found in zygotes originating from men with severe oligozoospermia(13.2%), followed by those originating from men with azoospermia(8.8%) and oligozoospermia(8.1%). Conclusion(s): Sex-chromosome aneuploidy and diploidy were the most frequent numerical-chromosome anomalies found in paternal pronuclei of ICSI 3PN zygotes. Surprisingly, no statistically significant difference in the incidence of numerical-chromosome anomalies was observed in the three groups of pronuclei derived from men with oligozoospermia, severe oligozoospermia, and azoospermia.展开更多
文摘在与人教版初中英语新教材(JEC)相配套的《教师教学用书》第一册p.167、第二册p.65和第三册p.43等多处出现了Play the tape for the studentsto listen这样的句子。笔者认为该句有欠妥之处,谨在此提出与编者商榷。 Michael Swan著《英语用法指南》第552页对句末介词做了十分清楚的说明:许多动词、形容词和名词与特定的介词一起连用。当这些动词、形容词和名词用于分句或句子的末尾时,介词常跟在的后面。例如:
文摘Objective: To investigate after intracytoplasmic sperminjection(ICSI) the paternal-derived pronuclei of zygotes with three pronuclei(3PN) for numerical-chromosome anomalies by using fluorescence in situ hybridization. Design: A total of 211 ICSI 3PN zygotes have been analyzed for numerical-chromosome anomalies in paternally derived pronuclei and compared with the group of 82 zygotes originated during IVF. In the ICSI group, 163 zygotes were evaluated for numerical-chromosome anomalies by using DNA probes for chromosomes 18, X, and Y, and 48 zygotes, for chromosomes 21, X, and Y. In the IVF group, 68 zygotes were evaluated for numerical-chromosome anomalies by using probes for chromosomes 18, X, and Y, and 14 zygotes, by using chromosomes 21, X, and Y. Setting and Patient(s): Tripronuclear zygotes were obtained from 74 and 176 patients participating in IVF and ICSI treatment cycles at a university hospital in Switzerland. Intervention(s): To evaluate the frequency of numerical-chromosome anomalies in different populations of infertile patients, a total of 211 ICSI zygotes were divided into three groups of zygotes from men with oligozoospermia(n=124), severe oligozoosper-mia(n=53), and azoospermia(n=34). Main Outcome Measure(s): Incidence of sex-chromosome aneuploidy, diploidy, and aneuploidy for chromosomes 18 or 21. Result(s): Overall incidence of numerical-chromosome anomalies in paternal-derived pronuclei after ICSI(9.5%) was significantly higher than the rate found in paternal-derived pronuclei of IVF zygotes(1.2%). Among ICSI zygotes, sex-chromosome aneuploidy(5.2%) and diploidy(2.8%) were two dominant numerical anomalies in paternal-derived pronuclei. In contrast, aneuploidy for autosomes 18 or 21 was not significantly different when comparing ICSI with IVF zygotes. Regarding different groups of infertile patients, the highest incidence of numerical chromosome anomalies was found in zygotes originating from men with severe oligozoospermia(13.2%), followed by those originating from men with azoospermia(8.8%) and oligozoospermia(8.1%). Conclusion(s): Sex-chromosome aneuploidy and diploidy were the most frequent numerical-chromosome anomalies found in paternal pronuclei of ICSI 3PN zygotes. Surprisingly, no statistically significant difference in the incidence of numerical-chromosome anomalies was observed in the three groups of pronuclei derived from men with oligozoospermia, severe oligozoospermia, and azoospermia.