AIM: To determine the features of microsatellite alterations and their association with clinicopathological characteristics of hepatocellular carcinoma (HCC). METHODS: Loss of heterozygosity (LOH) and microsatellite i...AIM: To determine the features of microsatellite alterations and their association with clinicopathological characteristics of hepatocellular carcinoma (HCC). METHODS: Loss of heterozygosity (LOH) and microsatellite instability (MSI) of 55 microsatellite loci were detected with PCR-based microsatellite polymorphism analyses in tumors and corresponding noncancerous liver tissues of 56 surgically resected HCCs using the MegaBACE 500 automatic DNA analysis system.RESULTS: LOH was found in 44 of 56 HCCs (78.6%) at one or several loci. Frequencies of LOH on 1p, 4q, 8p,16q, and 17p were 69.6% (39/56), 71.4% (40/56), 66.1% (37/56), 66.1% (37/56), and 64.3% (36/56), respectively. MSI was found in 18 of 56 HCCs (32.1%) at one or several loci. Ten of fifty-six (17.9%) HCCs had MSI-H. Serum HBV infection, alpha-fetoprotein concentration, tumor size, cirrhosis, histological grade, tumor capsule, as well as tumor intrahepatic metastasis, might be correlated with LOH on certain chromosome regions. CONCLUSION: Frequent microsatellite alterations exist in HCC. LOH, which represents a tumor suppressor gene pathway, plays a more important role in hepatocarcinogenesis. MSI, which represents a mismatch repair genepathway, is a rare event during liver carcinogenesis. Furthermore, LOH on certain chromosome regions may be correlated with clinicopathological characteristics in HCC.展开更多
The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral educatio...The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral education work with university students to explore innovative ideas and innovative approaches from the perspective of interpersonal communication, political science, and sociology under the new media environment. Then the article will put forward countermeasures and improvement strategies.展开更多
At present, a new teaching model - Project Approach rises in English education. Project teaching is a student-centered, inquiry-centered practice, with project activities centered learning model. Project teaching stud...At present, a new teaching model - Project Approach rises in English education. Project teaching is a student-centered, inquiry-centered practice, with project activities centered learning model. Project teaching students focus on learning strategies to help students become independent learners, to improve students' motivation to help students learn practical ability, communication skills, collaboration skills, creative thinking skills and the ability to solve practical problems. Project-based learning in the late 1990s was introduced in China. Within ten years, research project studying abroad connotation, significance and theoretical foundation, extension are applied research to classroom practice. However, most of the research object of the project is teaching primary and secondary students, higher education, adult education and general higher education students in science and engineering students. Research related to the field of English teaching is not much; the theory is applied to the case of teaching practice rarely. Therefore, this article introduced the project teaching college English classroom, through the implementation of the teaching aims to stimulate the enthusiasm of the students, so that students learn more explicit goals, enhance self- confidence and motivation to learn, to develop their creativity, initiative and independent learning and the purpose of learning ability.展开更多
This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.I...This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.It establishes an empirical model to estimate the spatial agglomeration effects of creative industries on regional TFP growth,using China′s provincial panel data during the period of 2003 to 2010.We found that the creative industries agglomeration(CIA)has significant and positive impact on regional TFP growth.The result also implies that the CIA can facilitate regional TFP growth through promoting regional innovation instead of improving regional efficiency.Therefore,we argue that policy makers should take some measures to retain and establish more creative zones.展开更多
Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual ...Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual policy, the Singapore government has been committed to creating a pool of bicultural talents, by supplementing the teaching of Chinese language with classes on Chinese literature and culture. This thesis seeks to understand the pros and cons of Chinese literature education in Singapore by analysing its development over the years. The teaching of Chinese literature began with the first wave of Chinese migration to Nanyang in the 19th century, and from there, it went through three phases of development: relocation, adjustment, and burgeoning.展开更多
Two new Professors,Prof.Xu Xiaonian and Prof,Xu Dingbohave joined CEIBS since 2004,prof,Xu Xiaonian is Professorof Finance and Economy and Prof,Xu Dingbo is Associate Professor of Accounting.
The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect kn...The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect knowledge learned during classes with several practical activities. They can provide a huge integration between the students and the professors in order to achieve better results in the pedagogical, structural and organizational parts of an engineering major degree. Therefore, the project goes through the impact of each entity in the student's life and the advantages to professional future, focusing the presence of these organizations in the Electrical Engineering Course of Federal University of Rio Grande do Norte.展开更多
Qichang Dong was a famous calligraphy and painting artist in ancient China. The theory of southern and northern schools proposed by him was a conclusion to traditional Chinese landscape painting art, and played an inc...Qichang Dong was a famous calligraphy and painting artist in ancient China. The theory of southern and northern schools proposed by him was a conclusion to traditional Chinese landscape painting art, and played an incomparable function in the traditional Chinese painting history in comparison with other painting theories. In the painting history, there were the theory of "pre-Dong" and the theory of "post-Dong" . In this paper, by starting from Qichang Dong' s "theory of southern and northern schoots" , the homogeneities between traditional Chinese music and painting arts are analyzed from the principle of spirit and the principle of technology, so that the homogeneities between traditional Chinese music and painting arts are explored in aesthetic concept and actual art creation.展开更多
It is very innovative significance that Chinese Literary Anthropology invents the Great Tradition in the new century and puts forward series of theoretical propositions and academic points based on it. The new Great T...It is very innovative significance that Chinese Literary Anthropology invents the Great Tradition in the new century and puts forward series of theoretical propositions and academic points based on it. The new Great Tradition transforms the opposition between the Great and Little Tradition of American anthropology, and makes the new concepts gain the legitimacy of the cultural values transferred from the old terms. It dates the second coded significance of the written culture from the material narrative and the image narrative of the oral tradition, and highlights the generative and primary of the symbolic significance. It also questions the authenticity of the written representation, endows the truth and credibility to the material and image representation, and manifests the imaginative and expression of the early human culture. Though its theoretical innovation inverts the binary opposition structure, and it wants to jump out of knowledge limits of dual structure such as structure and destruction, objective and subjective, material and spiritual.展开更多
We explore the idea of current university teaching reform of Chinese art, the contemporary Chinese painting cannot help with the status quo and reform. Because after all, the fundamental purpose of teaching Chinese pa...We explore the idea of current university teaching reform of Chinese art, the contemporary Chinese painting cannot help with the status quo and reform. Because after all, the fundamental purpose of teaching Chinese painting is to train a large number of innovative awareness and skills of professionals in order to promote the prosperity and development of Chinese painting. So, therefore, to reform the teaching of Chinese painting not only should be synchronized with the innovation of Chinese painting, Chinese painting should be involved in the development and reform of a series of important topics discussed making forward-looking thinking. Starting from the basic characteristics of painting, we are to explore ways to image modeling and imagery observation method according to melting into the hold of the art teaching among Chinese oaintin~ is one of a fundamental issue.展开更多
Objective: To evaluate the sensitivity and specificity of CT scan findings in patients with blunt abdominal trauma admitted to the university hospital. Methods: All the patients with blunt abdominal trauma admitted ...Objective: To evaluate the sensitivity and specificity of CT scan findings in patients with blunt abdominal trauma admitted to the university hospital. Methods: All the patients with blunt abdominal trauma admitted at a tertiary teaching trauma center in Iran between 2005 and 2007 were enrolled in this study. In the absence of any clinical manifestations, the patients underwent a diagnostic CT scan. Laparatomy was performed in those with positive CT results. Others were observed for 48 hours and discharged in case no problem was reported; otherwise they underwent laparatomy. Information on patients' demographic data, mechanism of trauma, indication for CT scan, CT scan findings, results of laparotomy were gathered. The sensitivity, specificity and accuracy of the CT-scan images in regard with the organ injured were calculated. The sensitivity, specificity and accuracy of the CT scan were calculated in each case. Results: CT scan had the highest sensitivity for detecting the injuries to liver (100%) and spleen (86.6%). The specificity of the method for detecting retroperitoneal hematoma (100%) and injuries to kidney (93.5%) was higher than other organs. The accuracy of CT images to detect the injuries to spleen, liver, kidney and retroperitoneal hematoma was reported to be 96.1%, 94.4%, 91.6% and 91.6% respectively. Conclusion: The findings of the present study reveal that CT scan could be considered as a good choice, especially for patients with blunt abdominal trauma in teaching hospitals where the radiologic academic staff is not present in the hospital in the night shifts.展开更多
To scrutinize the epidemiological characteristics of assaultive injuries in Sichuan province, China. Methods: A survey of all cases of assaultive injuries reported by police was performed during 8 years in eight cou...To scrutinize the epidemiological characteristics of assaultive injuries in Sichuan province, China. Methods: A survey of all cases of assaultive injuries reported by police was performed during 8 years in eight counties of Sichuan province, China. A total of 2862 victims and 2856 offenders were registered. Results: The majority of victims and offenders were young men at the age of 20-39 and only received an education at secondary school or primary school. The largest fraction of these cases took place at farm or by-place during 10.00-11.00 o'clock, 16.00-17.00 o'clock and 20.00-21.00 o'clock. The tangles caused by trifles were the most common factors inducing assaultive injuries and accounted for 42.1 percent of the causes of assaults. Blunt injuries were mainly caused by punching (40%) and kicking (17. 2%). About 37.3% of the lesions seriously happened in the regions of face and head. Open wounds accounted for 40.3 % of these different injuries. Conclusions: It is valuable to take some specific measures to prevent and control assaultive injuries according to their territorial characteristics.展开更多
Innovation of contemporary Chinese philosophy should be conducted in the light of the spirit of the times that should be embodied in a new philosophy and the necessary academic character determined by the spirit of th...Innovation of contemporary Chinese philosophy should be conducted in the light of the spirit of the times that should be embodied in a new philosophy and the necessary academic character determined by the spirit of the times. It means the construction of a new philosophy that returns to primitive philosophy in terms of research scope, follows the example of Marxist philosophy in terms of research approach, and inherits and develops previous Chinese and Western philosophy in terms of research content. This new philosophy centered on the spirit of harmony is termed "post-modern Marxist philosophy."展开更多
Research on modern Chinese literature has achieved results that have attracted wide attention. However, its state of near "saturation" has placed it in a dilemma with no clear way forward. Finding new academic growt...Research on modern Chinese literature has achieved results that have attracted wide attention. However, its state of near "saturation" has placed it in a dilemma with no clear way forward. Finding new academic growth points has become exceptionally important and urgent. The relationship between the "culture of calligraphy" and "modem Chinese writers" is virtually a research blank and has so Ihr attracted regrettably little attention. In fact, many modem Chinese writers have had close ties with calligraphy, making important contributions to its collection, creation and scholarly exploration. Conversely, the culture of calligraphy has exerted a profound influence on such things as the mode of existence, textual forms, emotional expression, ways of thought and aesthetic tastes of modem literature. Moreover, an examination of this relationship may stimulate us to reflect more deeply on literature, calligraphy, culture, education and related issues, which may help us gain a larger space for the development of Chinese culture and literature in the new century.展开更多
基金Supported by the National Natural Science Foundation of China,No. 30370645the Hundred Leading Scientists Program of the Public Health Sector of Shanghai, No. 98BR007
文摘AIM: To determine the features of microsatellite alterations and their association with clinicopathological characteristics of hepatocellular carcinoma (HCC). METHODS: Loss of heterozygosity (LOH) and microsatellite instability (MSI) of 55 microsatellite loci were detected with PCR-based microsatellite polymorphism analyses in tumors and corresponding noncancerous liver tissues of 56 surgically resected HCCs using the MegaBACE 500 automatic DNA analysis system.RESULTS: LOH was found in 44 of 56 HCCs (78.6%) at one or several loci. Frequencies of LOH on 1p, 4q, 8p,16q, and 17p were 69.6% (39/56), 71.4% (40/56), 66.1% (37/56), 66.1% (37/56), and 64.3% (36/56), respectively. MSI was found in 18 of 56 HCCs (32.1%) at one or several loci. Ten of fifty-six (17.9%) HCCs had MSI-H. Serum HBV infection, alpha-fetoprotein concentration, tumor size, cirrhosis, histological grade, tumor capsule, as well as tumor intrahepatic metastasis, might be correlated with LOH on certain chromosome regions. CONCLUSION: Frequent microsatellite alterations exist in HCC. LOH, which represents a tumor suppressor gene pathway, plays a more important role in hepatocarcinogenesis. MSI, which represents a mismatch repair genepathway, is a rare event during liver carcinogenesis. Furthermore, LOH on certain chromosome regions may be correlated with clinicopathological characteristics in HCC.
文摘The new media especially the use of mobile phone for information has a profound impact on contemporary university students' behavior, psychology, and way of thinking. This article will elaborate on the moral education work with university students to explore innovative ideas and innovative approaches from the perspective of interpersonal communication, political science, and sociology under the new media environment. Then the article will put forward countermeasures and improvement strategies.
文摘At present, a new teaching model - Project Approach rises in English education. Project teaching is a student-centered, inquiry-centered practice, with project activities centered learning model. Project teaching students focus on learning strategies to help students become independent learners, to improve students' motivation to help students learn practical ability, communication skills, collaboration skills, creative thinking skills and the ability to solve practical problems. Project-based learning in the late 1990s was introduced in China. Within ten years, research project studying abroad connotation, significance and theoretical foundation, extension are applied research to classroom practice. However, most of the research object of the project is teaching primary and secondary students, higher education, adult education and general higher education students in science and engineering students. Research related to the field of English teaching is not much; the theory is applied to the case of teaching practice rarely. Therefore, this article introduced the project teaching college English classroom, through the implementation of the teaching aims to stimulate the enthusiasm of the students, so that students learn more explicit goals, enhance self- confidence and motivation to learn, to develop their creativity, initiative and independent learning and the purpose of learning ability.
基金Under the auspices of National Natural Science Foundation of China(No.71172213,71171183)Ministry of Educa-tion,Humanities and Social Sciences Project(No.09YJA630153,10YJA790260)+1 种基金National Social Science Foundation of China(No.08&ZD043)Australian Research Council,and Chinese Academy of Sciences(CAS)Special Grant for Postgraduate Research,Inno-vation and Practice
文摘This paper falls into the broad area of economic geography and economics of creativity,and it presents an alternative approach to explain why total factor productivity(TFP)growth is different across China′s regions.It establishes an empirical model to estimate the spatial agglomeration effects of creative industries on regional TFP growth,using China′s provincial panel data during the period of 2003 to 2010.We found that the creative industries agglomeration(CIA)has significant and positive impact on regional TFP growth.The result also implies that the CIA can facilitate regional TFP growth through promoting regional innovation instead of improving regional efficiency.Therefore,we argue that policy makers should take some measures to retain and establish more creative zones.
文摘Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual policy, the Singapore government has been committed to creating a pool of bicultural talents, by supplementing the teaching of Chinese language with classes on Chinese literature and culture. This thesis seeks to understand the pros and cons of Chinese literature education in Singapore by analysing its development over the years. The teaching of Chinese literature began with the first wave of Chinese migration to Nanyang in the 19th century, and from there, it went through three phases of development: relocation, adjustment, and burgeoning.
文摘Two new Professors,Prof.Xu Xiaonian and Prof,Xu Dingbohave joined CEIBS since 2004,prof,Xu Xiaonian is Professorof Finance and Economy and Prof,Xu Dingbo is Associate Professor of Accounting.
文摘The project analyzes the student's participation in complementary activities such as Education Tutorial Program, Junior Company and Academic Center. These organizations have the goal to improve, expand and connect knowledge learned during classes with several practical activities. They can provide a huge integration between the students and the professors in order to achieve better results in the pedagogical, structural and organizational parts of an engineering major degree. Therefore, the project goes through the impact of each entity in the student's life and the advantages to professional future, focusing the presence of these organizations in the Electrical Engineering Course of Federal University of Rio Grande do Norte.
文摘Qichang Dong was a famous calligraphy and painting artist in ancient China. The theory of southern and northern schools proposed by him was a conclusion to traditional Chinese landscape painting art, and played an incomparable function in the traditional Chinese painting history in comparison with other painting theories. In the painting history, there were the theory of "pre-Dong" and the theory of "post-Dong" . In this paper, by starting from Qichang Dong' s "theory of southern and northern schoots" , the homogeneities between traditional Chinese music and painting arts are analyzed from the principle of spirit and the principle of technology, so that the homogeneities between traditional Chinese music and painting arts are explored in aesthetic concept and actual art creation.
文摘It is very innovative significance that Chinese Literary Anthropology invents the Great Tradition in the new century and puts forward series of theoretical propositions and academic points based on it. The new Great Tradition transforms the opposition between the Great and Little Tradition of American anthropology, and makes the new concepts gain the legitimacy of the cultural values transferred from the old terms. It dates the second coded significance of the written culture from the material narrative and the image narrative of the oral tradition, and highlights the generative and primary of the symbolic significance. It also questions the authenticity of the written representation, endows the truth and credibility to the material and image representation, and manifests the imaginative and expression of the early human culture. Though its theoretical innovation inverts the binary opposition structure, and it wants to jump out of knowledge limits of dual structure such as structure and destruction, objective and subjective, material and spiritual.
文摘We explore the idea of current university teaching reform of Chinese art, the contemporary Chinese painting cannot help with the status quo and reform. Because after all, the fundamental purpose of teaching Chinese painting is to train a large number of innovative awareness and skills of professionals in order to promote the prosperity and development of Chinese painting. So, therefore, to reform the teaching of Chinese painting not only should be synchronized with the innovation of Chinese painting, Chinese painting should be involved in the development and reform of a series of important topics discussed making forward-looking thinking. Starting from the basic characteristics of painting, we are to explore ways to image modeling and imagery observation method according to melting into the hold of the art teaching among Chinese oaintin~ is one of a fundamental issue.
文摘Objective: To evaluate the sensitivity and specificity of CT scan findings in patients with blunt abdominal trauma admitted to the university hospital. Methods: All the patients with blunt abdominal trauma admitted at a tertiary teaching trauma center in Iran between 2005 and 2007 were enrolled in this study. In the absence of any clinical manifestations, the patients underwent a diagnostic CT scan. Laparatomy was performed in those with positive CT results. Others were observed for 48 hours and discharged in case no problem was reported; otherwise they underwent laparatomy. Information on patients' demographic data, mechanism of trauma, indication for CT scan, CT scan findings, results of laparotomy were gathered. The sensitivity, specificity and accuracy of the CT-scan images in regard with the organ injured were calculated. The sensitivity, specificity and accuracy of the CT scan were calculated in each case. Results: CT scan had the highest sensitivity for detecting the injuries to liver (100%) and spleen (86.6%). The specificity of the method for detecting retroperitoneal hematoma (100%) and injuries to kidney (93.5%) was higher than other organs. The accuracy of CT images to detect the injuries to spleen, liver, kidney and retroperitoneal hematoma was reported to be 96.1%, 94.4%, 91.6% and 91.6% respectively. Conclusion: The findings of the present study reveal that CT scan could be considered as a good choice, especially for patients with blunt abdominal trauma in teaching hospitals where the radiologic academic staff is not present in the hospital in the night shifts.
文摘To scrutinize the epidemiological characteristics of assaultive injuries in Sichuan province, China. Methods: A survey of all cases of assaultive injuries reported by police was performed during 8 years in eight counties of Sichuan province, China. A total of 2862 victims and 2856 offenders were registered. Results: The majority of victims and offenders were young men at the age of 20-39 and only received an education at secondary school or primary school. The largest fraction of these cases took place at farm or by-place during 10.00-11.00 o'clock, 16.00-17.00 o'clock and 20.00-21.00 o'clock. The tangles caused by trifles were the most common factors inducing assaultive injuries and accounted for 42.1 percent of the causes of assaults. Blunt injuries were mainly caused by punching (40%) and kicking (17. 2%). About 37.3% of the lesions seriously happened in the regions of face and head. Open wounds accounted for 40.3 % of these different injuries. Conclusions: It is valuable to take some specific measures to prevent and control assaultive injuries according to their territorial characteristics.
文摘Innovation of contemporary Chinese philosophy should be conducted in the light of the spirit of the times that should be embodied in a new philosophy and the necessary academic character determined by the spirit of the times. It means the construction of a new philosophy that returns to primitive philosophy in terms of research scope, follows the example of Marxist philosophy in terms of research approach, and inherits and develops previous Chinese and Western philosophy in terms of research content. This new philosophy centered on the spirit of harmony is termed "post-modern Marxist philosophy."
文摘Research on modern Chinese literature has achieved results that have attracted wide attention. However, its state of near "saturation" has placed it in a dilemma with no clear way forward. Finding new academic growth points has become exceptionally important and urgent. The relationship between the "culture of calligraphy" and "modem Chinese writers" is virtually a research blank and has so Ihr attracted regrettably little attention. In fact, many modem Chinese writers have had close ties with calligraphy, making important contributions to its collection, creation and scholarly exploration. Conversely, the culture of calligraphy has exerted a profound influence on such things as the mode of existence, textual forms, emotional expression, ways of thought and aesthetic tastes of modem literature. Moreover, an examination of this relationship may stimulate us to reflect more deeply on literature, calligraphy, culture, education and related issues, which may help us gain a larger space for the development of Chinese culture and literature in the new century.