The effects of zinc deficiency on the serum cortisol and adrenocorticotrophic hormone (ACTH) concentration,and the cerebrum nitric oxide synthase (NOS) activity in rats were studied.Growing rats were allotted to three...The effects of zinc deficiency on the serum cortisol and adrenocorticotrophic hormone (ACTH) concentration,and the cerebrum nitric oxide synthase (NOS) activity in rats were studied.Growing rats were allotted to three groups,which were zinc deficiency (ZD),paired fed (PF) and zinc supplementation after feeding zinc deficient food for 21 days (ZS).The duration of feed test was 35 days.Compared with PF rats,serum cortisol concentration in ZD ones was significantly increased,whereas serum ACTH concentration and cerebrum NOS activity were significantly decreased.The results suggested that zinc might influence the metabolism of hypothalamic hypophysial adrenocortical axis and NOS.展开更多
Exploring the production and application of clean energy has always been the core of sustainable development.As a clean and sustainable technology,electrocatalysis has been receiving widespread attention.It is crucial...Exploring the production and application of clean energy has always been the core of sustainable development.As a clean and sustainable technology,electrocatalysis has been receiving widespread attention.It is crucial to achieve efficient,stable and cheap electrocatalysts.However,the traditional“trial and error”method is time-consuming,laborious and costly.In recent years,with the significant increase in computing power,computations have played an important role in electrocatalyst design.Nevertheless,it is still difficult to search for advanced electrocatalysts in the vast chemical space through traditional density functional theory(DFT)computations.Fortunately,the development of machine learning and interdisciplinary integration will inject new impetus into targeted design of electrocatalysts.Machine learning is able to predict electrochemical performances with an accuracy close to DFT.Here we provide an overview of the application of machine learning in electrocatalyst design,including the prediction of structure,thermodynamic properties and kinetic barriers.We also discuss the potential of explicit solvent model combined with machine learning molecular dynamics in this field.Finally,the favorable circumstances and challenges are outlined for the future development of machine learning in electrocatalysis.The studies on electrochemical processes by machine learning will further realize targeted design of high-efficiency electrocatalysts.展开更多
This paper explores some effective tactics on the teaching of English. It starts with the introduction of the importance of learning English, then it reveals the qualities and useful strategies that a teacher of Engli...This paper explores some effective tactics on the teaching of English. It starts with the introduction of the importance of learning English, then it reveals the qualities and useful strategies that a teacher of English should master if he or she wants to make his or her lessons successful. It also conducts the analysis of how these tactics interact in the classroom teaching. The paper concludes that examining effective ways of teaching is useful in helping teachers either in their academic field or in their professional development.展开更多
Li （lithium）, a mood stabilizer has anti-inflammatory effect. However, in clinical practice, Li can be administered together with other antidepressants drugs, such as FLX （fluoxetine）, IMI （imipramine）, NOR （no...Li （lithium）, a mood stabilizer has anti-inflammatory effect. However, in clinical practice, Li can be administered together with other antidepressants drugs, such as FLX （fluoxetine）, IMI （imipramine）, NOR （nortriptyline） and ESC （escitalopram）. As interaction between Li and these antidepressant drugs on inflammatory modulation has not been investigated yet, we performed an in vitro protocol using a non-human macrophage cell line. Oxidative and inflammatory markers, as well as cell cycle analysis and cytokine gene expressions were compared among treatments. An IR （inflammatory ratio） was calculated based on the following oxidative-inflammatory variables： nitric oxide, superoxide anion, reactive oxygen molecules, cytokines IL-113, IL-6, TNF-ct and IL-10. The in vitro calculated IR data were validated through an in vivo analysis of 154 human subjects with similar IR. Li and control cells presented similar IR values. FLX, NOR and IMI increased slightly IR values indicating some proinflammatory effect, whereas ESC decreased IR values indicating some anti-inflammatory effect. However, cells exposed to Li ＋ ESC triggered a proinflammatory response on macrophages. Thus, IR comparison results suggest that the Li anti-inflammatory effect is not universal and could be influenced by both basal macrophage-inflammatory state and interaction of other psychiatric drugs. These results could be useful to understand some inconsistencies observed in human studies involving Li and other psychiatric drugs.展开更多
Starting from the fact that water is quite arguably the source of life, the authors agreed to set up a project on water and name it： ＂REFLECTION＂. Particular focus was placed on the following issues： water in natu...Starting from the fact that water is quite arguably the source of life, the authors agreed to set up a project on water and name it： ＂REFLECTION＂. Particular focus was placed on the following issues： water in nature, importance of water in human life, physical and chemical properties of water, protection of water in nature. The aim of the project was to make students aware of the importance of water for health as well as to help them develop a rational relationship towards drinking water. In order to find answers to the issues raised, the authors designed worksheets, PowerPoint presentations, educational games （ecological postcards, dominoes, memory games, etc.）. The authors even tried our hand at making a comic strip. Students learned about the influence of water on health, as well as about water content in particular foods. The long-term goal of the project is to introduce children to scientific approach and methodology. Through active participation and dialogue, students discover cooperative learning and acquire skills that will be beneficial to them as well as to the wider community. Working on the project, students＇ evidence that the role of an individual is a key one in building a better world. This insight helps develop their civic skills and attitudes that serve as the starting point for environmental education. The authors made numerous adaptations and implemented individual approach with the goal of training students for independent work and life according to their personal abilities in line with the principles of inclusive education. Students conduct experiments following step-by-step instructions on specially adapted worksheets. Each student gets positive feedback and experiences the joy of success that leads to the development of self-confidence and love of work and learning.展开更多
An equivalent amount of metallurgical slag, water-quenched slag powder and activator was substituted for a part of cement to prepare concretes at strength grades ofC25, C30 and C40. Thanks to the filling effect, pozzo...An equivalent amount of metallurgical slag, water-quenched slag powder and activator was substituted for a part of cement to prepare concretes at strength grades ofC25, C30 and C40. Thanks to the filling effect, pozzolanic effect, raicro-aggregate effect, and improvement of pore structure, the prepared concretes not only had greater strength compared with reference concrete, but also had greater impermeability and frost-resistance. Moreover, the expansion reactions between alkali and aggregates were effectively inhibited. The slag and activator can serve as the raw materials for green concretes.展开更多
The study area is located in Duhok and Sulaimania province in Kurdistan region, lraq. Study soils developed from parent material that has derived from limestone. Randomize, composed and disturbed surface soil samples ...The study area is located in Duhok and Sulaimania province in Kurdistan region, lraq. Study soils developed from parent material that has derived from limestone. Randomize, composed and disturbed surface soil samples were collected. The bulk soils were air dried, crushed and passed through 2 mm sieve. Standard methods were used for chemical, physical, geotechnical and mineralogical analyses of soil samples. The results indicated that the study soils texture were clay to loam clay, this texture was considered as suitable for ceramic and pottery industries as a result of increasing clay contents that ranged between 301 g/kg and 676 g/kg. Soil consistence depending on geotechnical properties increased the ability of study soils for resistance rapture and deformation. Existence the high amount of cementing agents in study soils such as organic matter, iron oxides and particularly total carbonate （247.2-308.8 g/kg） act to reduce the bad effect of the smectite minerals group （high shrinkage） in soils of study locations through increasing the resistance of these soils for rupture and deformation. The existing of Kaolinite, palygorskite and chlorite allows clay to be dried in ceramic and pottery industries without cracking from shrinkage. Study soils were different in their colors as a result of existence, different pigmentation materials that led to coloring soils with different colors in turn caused coloring of pottery and ceramic materials. Since, there are no available academic studies or researches about this subject in Kurdistan region in addition the clay pottery and ceramic sector still has a good market at the same time using this type of soils for arts, therefore, this study was conducted.展开更多
This paper analyzes the current situation and problems of the of gardening flowers professional practice teaching, including： rigid and obsolete teaching mode, student learning enthusiasm deficiencies; practice over ...This paper analyzes the current situation and problems of the of gardening flowers professional practice teaching, including： rigid and obsolete teaching mode, student learning enthusiasm deficiencies; practice over a single, and the lack of opportunity to practice and platform; lack of software and hardware construction, internship bases imperfect; lack of teachers＇ quality, teaching lack the times. The paper proposes a gardening the flowers professional practice teaching improvement strategies, including： innovative teaching ideas, improvement of education quality; comprehensive local conditions perfect practice, promote the construction and improvement of the practice platform; increase funding, improve the practice teachin~ base; to enhance the training and continuing education to improve practice, the overall quality of the course insla＇uctor.展开更多
基金SupportedbyNationalNaturalScienceFoundationofChina (No 3970 0 12 0 )andbyNationalEducationMinistrygrants (No A9410 7)
文摘The effects of zinc deficiency on the serum cortisol and adrenocorticotrophic hormone (ACTH) concentration,and the cerebrum nitric oxide synthase (NOS) activity in rats were studied.Growing rats were allotted to three groups,which were zinc deficiency (ZD),paired fed (PF) and zinc supplementation after feeding zinc deficient food for 21 days (ZS).The duration of feed test was 35 days.Compared with PF rats,serum cortisol concentration in ZD ones was significantly increased,whereas serum ACTH concentration and cerebrum NOS activity were significantly decreased.The results suggested that zinc might influence the metabolism of hypothalamic hypophysial adrenocortical axis and NOS.
文摘Exploring the production and application of clean energy has always been the core of sustainable development.As a clean and sustainable technology,electrocatalysis has been receiving widespread attention.It is crucial to achieve efficient,stable and cheap electrocatalysts.However,the traditional“trial and error”method is time-consuming,laborious and costly.In recent years,with the significant increase in computing power,computations have played an important role in electrocatalyst design.Nevertheless,it is still difficult to search for advanced electrocatalysts in the vast chemical space through traditional density functional theory(DFT)computations.Fortunately,the development of machine learning and interdisciplinary integration will inject new impetus into targeted design of electrocatalysts.Machine learning is able to predict electrochemical performances with an accuracy close to DFT.Here we provide an overview of the application of machine learning in electrocatalyst design,including the prediction of structure,thermodynamic properties and kinetic barriers.We also discuss the potential of explicit solvent model combined with machine learning molecular dynamics in this field.Finally,the favorable circumstances and challenges are outlined for the future development of machine learning in electrocatalysis.The studies on electrochemical processes by machine learning will further realize targeted design of high-efficiency electrocatalysts.
文摘This paper explores some effective tactics on the teaching of English. It starts with the introduction of the importance of learning English, then it reveals the qualities and useful strategies that a teacher of English should master if he or she wants to make his or her lessons successful. It also conducts the analysis of how these tactics interact in the classroom teaching. The paper concludes that examining effective ways of teaching is useful in helping teachers either in their academic field or in their professional development.
文摘Li （lithium）, a mood stabilizer has anti-inflammatory effect. However, in clinical practice, Li can be administered together with other antidepressants drugs, such as FLX （fluoxetine）, IMI （imipramine）, NOR （nortriptyline） and ESC （escitalopram）. As interaction between Li and these antidepressant drugs on inflammatory modulation has not been investigated yet, we performed an in vitro protocol using a non-human macrophage cell line. Oxidative and inflammatory markers, as well as cell cycle analysis and cytokine gene expressions were compared among treatments. An IR （inflammatory ratio） was calculated based on the following oxidative-inflammatory variables： nitric oxide, superoxide anion, reactive oxygen molecules, cytokines IL-113, IL-6, TNF-ct and IL-10. The in vitro calculated IR data were validated through an in vivo analysis of 154 human subjects with similar IR. Li and control cells presented similar IR values. FLX, NOR and IMI increased slightly IR values indicating some proinflammatory effect, whereas ESC decreased IR values indicating some anti-inflammatory effect. However, cells exposed to Li ＋ ESC triggered a proinflammatory response on macrophages. Thus, IR comparison results suggest that the Li anti-inflammatory effect is not universal and could be influenced by both basal macrophage-inflammatory state and interaction of other psychiatric drugs. These results could be useful to understand some inconsistencies observed in human studies involving Li and other psychiatric drugs.
文摘Starting from the fact that water is quite arguably the source of life, the authors agreed to set up a project on water and name it： ＂REFLECTION＂. Particular focus was placed on the following issues： water in nature, importance of water in human life, physical and chemical properties of water, protection of water in nature. The aim of the project was to make students aware of the importance of water for health as well as to help them develop a rational relationship towards drinking water. In order to find answers to the issues raised, the authors designed worksheets, PowerPoint presentations, educational games （ecological postcards, dominoes, memory games, etc.）. The authors even tried our hand at making a comic strip. Students learned about the influence of water on health, as well as about water content in particular foods. The long-term goal of the project is to introduce children to scientific approach and methodology. Through active participation and dialogue, students discover cooperative learning and acquire skills that will be beneficial to them as well as to the wider community. Working on the project, students＇ evidence that the role of an individual is a key one in building a better world. This insight helps develop their civic skills and attitudes that serve as the starting point for environmental education. The authors made numerous adaptations and implemented individual approach with the goal of training students for independent work and life according to their personal abilities in line with the principles of inclusive education. Students conduct experiments following step-by-step instructions on specially adapted worksheets. Each student gets positive feedback and experiences the joy of success that leads to the development of self-confidence and love of work and learning.
文摘An equivalent amount of metallurgical slag, water-quenched slag powder and activator was substituted for a part of cement to prepare concretes at strength grades ofC25, C30 and C40. Thanks to the filling effect, pozzolanic effect, raicro-aggregate effect, and improvement of pore structure, the prepared concretes not only had greater strength compared with reference concrete, but also had greater impermeability and frost-resistance. Moreover, the expansion reactions between alkali and aggregates were effectively inhibited. The slag and activator can serve as the raw materials for green concretes.
文摘The study area is located in Duhok and Sulaimania province in Kurdistan region, lraq. Study soils developed from parent material that has derived from limestone. Randomize, composed and disturbed surface soil samples were collected. The bulk soils were air dried, crushed and passed through 2 mm sieve. Standard methods were used for chemical, physical, geotechnical and mineralogical analyses of soil samples. The results indicated that the study soils texture were clay to loam clay, this texture was considered as suitable for ceramic and pottery industries as a result of increasing clay contents that ranged between 301 g/kg and 676 g/kg. Soil consistence depending on geotechnical properties increased the ability of study soils for resistance rapture and deformation. Existence the high amount of cementing agents in study soils such as organic matter, iron oxides and particularly total carbonate （247.2-308.8 g/kg） act to reduce the bad effect of the smectite minerals group （high shrinkage） in soils of study locations through increasing the resistance of these soils for rupture and deformation. The existing of Kaolinite, palygorskite and chlorite allows clay to be dried in ceramic and pottery industries without cracking from shrinkage. Study soils were different in their colors as a result of existence, different pigmentation materials that led to coloring soils with different colors in turn caused coloring of pottery and ceramic materials. Since, there are no available academic studies or researches about this subject in Kurdistan region in addition the clay pottery and ceramic sector still has a good market at the same time using this type of soils for arts, therefore, this study was conducted.
文摘This paper analyzes the current situation and problems of the of gardening flowers professional practice teaching, including： rigid and obsolete teaching mode, student learning enthusiasm deficiencies; practice over a single, and the lack of opportunity to practice and platform; lack of software and hardware construction, internship bases imperfect; lack of teachers＇ quality, teaching lack the times. The paper proposes a gardening the flowers professional practice teaching improvement strategies, including： innovative teaching ideas, improvement of education quality; comprehensive local conditions perfect practice, promote the construction and improvement of the practice platform; increase funding, improve the practice teachin~ base; to enhance the training and continuing education to improve practice, the overall quality of the course insla＇uctor.
