牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教...牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。展开更多
牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教...牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。展开更多
牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教...牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。展开更多
牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教...牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。展开更多
To investigate the pharmacokinetic characteristics of moclobemide sustainedrelease tablets after multiple oral dose administration in healthy Chinese volunteers. MethodsMoclobemide sustained release tablets were given...To investigate the pharmacokinetic characteristics of moclobemide sustainedrelease tablets after multiple oral dose administration in healthy Chinese volunteers. MethodsMoclobemide sustained release tablets were given as a multiple oral dose regimen of 300 mg oncedaily for five consecutive days to 12 healthy volunteers. The concentrations of moclobemide inplasma were determined by reversed-phase high performance liquid chromatography. The partialpharmacokinetic parameters were calculated using 3p97 pharmacokinetic program. Results Theconcentration-time profile fitted an one-compartment model best. The steady-state pharmacokineticparameters of moclobemide sustained release tablets after multiple oral doses were as follows:C_(max) was (1 950 +- 156) μg· L^(-1), T_(max) was (6.00 +-1.55) h, T_(1/2(kel)) was (3.14 +-0.12)h, AUC_(ss 0-24) was (22 836 +- 1 842) μg·h· L^(-1), MRT was (7.68+-0.36) h, CL/F_((s)) was(20.2+-2.1) L·h^(-1), and V/F_((c)) was (91.4+-9.4) L, respectively. No marked adverse events werenoted during this study. Conclusion The formulation has a sustained-release effect and goodtolerance in the healthy volunteers, which provides useful information for clinical practice.展开更多
Multivariate statistical process monitoring and control (MSPM&C) methods for chemical process monitoring with statistical projection techniques such as principal component analysis (PCA) and partial least squares ...Multivariate statistical process monitoring and control (MSPM&C) methods for chemical process monitoring with statistical projection techniques such as principal component analysis (PCA) and partial least squares (PLS) are surveyed in this paper. The four-step procedure of performing MSPM&C for chemical process, modeling of processes, detecting abnormal events or faults, identifying the variable(s) responsible for the faults and diagnosing the source cause for the abnormal behavior, is analyzed. Several main research directions of MSPM&C reported in the literature are discussed, such as multi-way principal component analysis (MPCA) for batch process, statistical monitoring and control for nonlinear process, dynamic PCA and dynamic PLS, and on-line quality control by inferential models. Industrial applications of MSPM&C to several typical chemical processes, such as chemical reactor, distillation column, polymerization process, petroleum refinery units, are summarized. Finally, some concluding remarks and future considerations are made.展开更多
With the development of artificial intelligence, communication, computer and other related technologies, it becomes feasible to rebuild traditional railway with such advanced technologies in order to establish a new g...With the development of artificial intelligence, communication, computer and other related technologies, it becomes feasible to rebuild traditional railway with such advanced technologies in order to establish a new generation railway transport system. The railway intelligent transportation system is the trend of railway transportation system in China, and it is also the research focus of international railway transport industry. This paper presents the definition, characters, architecture, key technologies and developing pattern of the RITS(railway intelligent transportation system). Then three typical applications are introduced. Finally, the prospect of the RITS is summarized.展开更多
In order to get the price of a contingent claim with random interval payoff, a concept of fair price was proposed based on weighted expected utility maximization. After setting up a programming model of maximizing the...In order to get the price of a contingent claim with random interval payoff, a concept of fair price was proposed based on weighted expected utility maximization. After setting up a programming model of maximizing the weighted expected utility involving basic securities and contingent claim,and using techniques in optimization analysis,explicit expressions of the fair price interval for a contingent claim were derived. Relations between acceptable price interval and fair price interval were discussed. It is shown that all fair prices fit the demand for acceptability of a market.展开更多
Nature and its exploration is one of the most frequent objects of scientific research. Phenology can be described either as the study of natural events, or of biological events, in relation to climate. The Czech Hydro...Nature and its exploration is one of the most frequent objects of scientific research. Phenology can be described either as the study of natural events, or of biological events, in relation to climate. The Czech Hydrometeorological Institute operates phenological network (45 wild plants) with allergology important species within the observation program (the program includes among other species also the Common Hazel (Corylus avellana L.), the Common Alder (Alnus glutinosa (L.) Gaert.), the Silver Birch (Betula pendula Roth.), the Meadow Foxtail (Alopecurus pratensis L.) and the Cocks Foot (Dactyl& glomerata L.)). We have statistically evaluated the phenological stages closely connected with the pollen grains release into the air (the beginning of flowering-BBCH 61 and the end of flowering-BBCH 69) including maps creation. The processed period was within last twenty years 1991-2010. The maps were processed using geographic information systems (Application Clidata-GIS, method Clidata-DEM). The input data were used the mean dates of phenophase entrance from the twenty year period 1991-2010. The mean onset date of the beginning of flowering was between 24th February and the 24th March (the Common Hazel), between 6th March and 2nd April (the Common Alder), between 13th April and 7th May (the Silver Birch), between 5thMay and 23rd May (the Meadow Foxtail) and between 16th May and 12th June (the Cocks Foot). The mean onset date of the end of flowering was from 18th March till the 15th April (the Common Hazel), from 27th March till 19th April (the Common Alder), from 28th April till 21st May (the Silver Birch), from 25th May till 6th June (the Meadow Foxtail) and from 7th May till 23rd June (the Cocks Foot). The duration of flowering lasts on average with selected allergens as follows: 22-23 days with standard deviation 2.3-5.3 days (the Common Hazel), 14-15 days with standard deviation 2.1-2.7 days (the Common Alder), 17-21 days with standard deviation 1.8-4.2 days (the Silver Birch), 20 days with standard deviations 1.0-2.7 days (the Meadow Foxtail) and 20-22 days with standard deviation 1.3-4.0 days (the Cocks Foot). The phenological phases were much precipitated in the years 2000, 2007 and 2009, on the contrary the onsets were much delayed in the years 1991 and 1996. Part of selected species show an overall tendency to the earlierst onset on the low level of the statistics significance during the 20-year processed period.展开更多
When the microscopic particles was depicted by linear Schrodinger equation, we find that the particles have only a wave feature, thus, a series of difficulties and intense disputations occur in quantum mechanics. Thes...When the microscopic particles was depicted by linear Schrodinger equation, we find that the particles have only a wave feature, thus, a series of difficulties and intense disputations occur in quantum mechanics. These problems excite us to consider the nonlinear interactions among the particles or between the particle and background field, which is completely ignored in quantum mechanics. Thus we use the nonlinear Schrodinger equation to describe the natures of microscopic particles. In this case the natures and features of microscopic particles are considerably different from those in quantum mechanics, where the microscopic particles are localized and have truly a wave-particle duality. Meanwhile, they satisfy both the classical dynamics equation and Lagrangian and Hamilton equations and obey the conservation laws of mass, energy and momentum. These natures and features are due to the nonlinear interactions, which are generated in virtue of the interaction between the moved particles and background field through the mechanisms of self-trapping, self-focus and self-condensation. Finally, we verified experimentally the localization and wave-corpuscle features of microscopic particles described by the nonlinear Schrodinger equation using the properties of water soliton and optical-soliton depicted also by the nonlinear Schrodinger equation in water and optical fiber, respectively. Therefore, the new nonlinear quantum theory established on the basis of nonlinear Schrodinger equation is correct and credible. From this investigation we can not only solve difficulties and problems disputed for about a century by plenty of scientists in quantum mechanics but also promote the development of physics and enhance the knowledge and recognition levels to the essences of microscopic matter.展开更多
Black pepper (Piper nigrum L.) is an extensively used medicinal plant in Ayurvedic medicine since ancient times. Here we present Fourier transform infrared (FT-IR) and Fourier transform Raman (FT-Raman) spectra ...Black pepper (Piper nigrum L.) is an extensively used medicinal plant in Ayurvedic medicine since ancient times. Here we present Fourier transform infrared (FT-IR) and Fourier transform Raman (FT-Raman) spectra of black pepper powder, which reveal the presence of some specific functional groups, attributed to the different vibrational bands present. Through the assignment of the vibrational bands, black pepper is shown to have enough carboxyl dimer character, a feature that could make it effective in the treatment of the deadly disease vitiligo. Mineral composition reported with the help of XRF spectra strengthens this.展开更多
The RAX series paraxylene (PX) adsorbents RAX-2000A and RAX-3000, are developed by the Sinopec Re- search Institute of Petroleum Processing (RIPP) and manufactured by the Sinopec Catalyst Company. Performance test...The RAX series paraxylene (PX) adsorbents RAX-2000A and RAX-3000, are developed by the Sinopec Re- search Institute of Petroleum Processing (RIPP) and manufactured by the Sinopec Catalyst Company. Performance test of RAX-2000A showed that the average purity of the PX product reached 99.81%, with an average PX yield of 98.6% per pass. The new generation of PX adsorbents, RAX-3000 not only retains most advantages of the adsorbent RAX-2000A, but also has higher selective adsorption capacity by at least 8%. The actual unit production capability of the adsorbent RAX- 3000 was increased by about 18%. The RAX series PX adsorbents exhibited good adaptability to unfavorable feedstock containing high ethyl benzene (EB) fraction besides their better mechanical strength. Preliminary test results indicated that compared to the adsorbent RAX-2000A, the A/Fa and D/F relating to the adsorbent RAX-3000 were notably decreased due to the hi^her selective adsorotion canacitv of the adsorbent RAX-3000.展开更多
This paper applies fuzzy logic approach to examine consumer ethnocentrism level for Jordanians based on their socio-psychological variables namely, patriotism, nationalism and internationalism. To model the relationsh...This paper applies fuzzy logic approach to examine consumer ethnocentrism level for Jordanians based on their socio-psychological variables namely, patriotism, nationalism and internationalism. To model the relationships between three inputs namely, patriotism, nationalism and internationalism and one output ethnocentrism MATLAB ANFIS has been used, utilizing a sample of 341 Jordanians live in Amman city. Results indicate that fuzzy logic model can predict correctly consumers ethnocentric tendencies knowing their patriotic, nationalistic and internationalist feelings. Fuzzy logic approach shows that high level of nationalism leads consumers to be ethnocentric.展开更多
文摘牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。
文摘牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。
文摘牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。
文摘牛津大学出版社出版的《环境流行病学:研究方法与应用》的简体中文版已经由中国环境科学出版社正式出版。本书由美国加州大学欧文分校职业与环境卫生中心Dean Baker教授和西班牙巴塞罗那环境流行病学研究中心Mark J. Nieuwenhuijsen教授组织20余名相关学者共同编著,由中国环境科学研究院张金良研究员等组织翻译审校。该书是第一部关注研究方法与应用的环境流行病学著作,全书共有16章,以方法学原则和应用实践为重点解读环境流行病学。
文摘To investigate the pharmacokinetic characteristics of moclobemide sustainedrelease tablets after multiple oral dose administration in healthy Chinese volunteers. MethodsMoclobemide sustained release tablets were given as a multiple oral dose regimen of 300 mg oncedaily for five consecutive days to 12 healthy volunteers. The concentrations of moclobemide inplasma were determined by reversed-phase high performance liquid chromatography. The partialpharmacokinetic parameters were calculated using 3p97 pharmacokinetic program. Results Theconcentration-time profile fitted an one-compartment model best. The steady-state pharmacokineticparameters of moclobemide sustained release tablets after multiple oral doses were as follows:C_(max) was (1 950 +- 156) μg· L^(-1), T_(max) was (6.00 +-1.55) h, T_(1/2(kel)) was (3.14 +-0.12)h, AUC_(ss 0-24) was (22 836 +- 1 842) μg·h· L^(-1), MRT was (7.68+-0.36) h, CL/F_((s)) was(20.2+-2.1) L·h^(-1), and V/F_((c)) was (91.4+-9.4) L, respectively. No marked adverse events werenoted during this study. Conclusion The formulation has a sustained-release effect and goodtolerance in the healthy volunteers, which provides useful information for clinical practice.
基金Supported by the National High-Tech Development Program of China(No.863-511-920-011,2001AA411230).
文摘Multivariate statistical process monitoring and control (MSPM&C) methods for chemical process monitoring with statistical projection techniques such as principal component analysis (PCA) and partial least squares (PLS) are surveyed in this paper. The four-step procedure of performing MSPM&C for chemical process, modeling of processes, detecting abnormal events or faults, identifying the variable(s) responsible for the faults and diagnosing the source cause for the abnormal behavior, is analyzed. Several main research directions of MSPM&C reported in the literature are discussed, such as multi-way principal component analysis (MPCA) for batch process, statistical monitoring and control for nonlinear process, dynamic PCA and dynamic PLS, and on-line quality control by inferential models. Industrial applications of MSPM&C to several typical chemical processes, such as chemical reactor, distillation column, polymerization process, petroleum refinery units, are summarized. Finally, some concluding remarks and future considerations are made.
基金funded by the National Natural Science Foundation of China ( No. 61074151) Nation Science and Technology Support Program ( No. T1DB300020 and No. T1DB200010)Ministry of Railways Science and Technology Research Program ( No. 2006X023 and No. 2010X008)
文摘With the development of artificial intelligence, communication, computer and other related technologies, it becomes feasible to rebuild traditional railway with such advanced technologies in order to establish a new generation railway transport system. The railway intelligent transportation system is the trend of railway transportation system in China, and it is also the research focus of international railway transport industry. This paper presents the definition, characters, architecture, key technologies and developing pattern of the RITS(railway intelligent transportation system). Then three typical applications are introduced. Finally, the prospect of the RITS is summarized.
文摘In order to get the price of a contingent claim with random interval payoff, a concept of fair price was proposed based on weighted expected utility maximization. After setting up a programming model of maximizing the weighted expected utility involving basic securities and contingent claim,and using techniques in optimization analysis,explicit expressions of the fair price interval for a contingent claim were derived. Relations between acceptable price interval and fair price interval were discussed. It is shown that all fair prices fit the demand for acceptability of a market.
文摘Nature and its exploration is one of the most frequent objects of scientific research. Phenology can be described either as the study of natural events, or of biological events, in relation to climate. The Czech Hydrometeorological Institute operates phenological network (45 wild plants) with allergology important species within the observation program (the program includes among other species also the Common Hazel (Corylus avellana L.), the Common Alder (Alnus glutinosa (L.) Gaert.), the Silver Birch (Betula pendula Roth.), the Meadow Foxtail (Alopecurus pratensis L.) and the Cocks Foot (Dactyl& glomerata L.)). We have statistically evaluated the phenological stages closely connected with the pollen grains release into the air (the beginning of flowering-BBCH 61 and the end of flowering-BBCH 69) including maps creation. The processed period was within last twenty years 1991-2010. The maps were processed using geographic information systems (Application Clidata-GIS, method Clidata-DEM). The input data were used the mean dates of phenophase entrance from the twenty year period 1991-2010. The mean onset date of the beginning of flowering was between 24th February and the 24th March (the Common Hazel), between 6th March and 2nd April (the Common Alder), between 13th April and 7th May (the Silver Birch), between 5thMay and 23rd May (the Meadow Foxtail) and between 16th May and 12th June (the Cocks Foot). The mean onset date of the end of flowering was from 18th March till the 15th April (the Common Hazel), from 27th March till 19th April (the Common Alder), from 28th April till 21st May (the Silver Birch), from 25th May till 6th June (the Meadow Foxtail) and from 7th May till 23rd June (the Cocks Foot). The duration of flowering lasts on average with selected allergens as follows: 22-23 days with standard deviation 2.3-5.3 days (the Common Hazel), 14-15 days with standard deviation 2.1-2.7 days (the Common Alder), 17-21 days with standard deviation 1.8-4.2 days (the Silver Birch), 20 days with standard deviations 1.0-2.7 days (the Meadow Foxtail) and 20-22 days with standard deviation 1.3-4.0 days (the Cocks Foot). The phenological phases were much precipitated in the years 2000, 2007 and 2009, on the contrary the onsets were much delayed in the years 1991 and 1996. Part of selected species show an overall tendency to the earlierst onset on the low level of the statistics significance during the 20-year processed period.
文摘When the microscopic particles was depicted by linear Schrodinger equation, we find that the particles have only a wave feature, thus, a series of difficulties and intense disputations occur in quantum mechanics. These problems excite us to consider the nonlinear interactions among the particles or between the particle and background field, which is completely ignored in quantum mechanics. Thus we use the nonlinear Schrodinger equation to describe the natures of microscopic particles. In this case the natures and features of microscopic particles are considerably different from those in quantum mechanics, where the microscopic particles are localized and have truly a wave-particle duality. Meanwhile, they satisfy both the classical dynamics equation and Lagrangian and Hamilton equations and obey the conservation laws of mass, energy and momentum. These natures and features are due to the nonlinear interactions, which are generated in virtue of the interaction between the moved particles and background field through the mechanisms of self-trapping, self-focus and self-condensation. Finally, we verified experimentally the localization and wave-corpuscle features of microscopic particles described by the nonlinear Schrodinger equation using the properties of water soliton and optical-soliton depicted also by the nonlinear Schrodinger equation in water and optical fiber, respectively. Therefore, the new nonlinear quantum theory established on the basis of nonlinear Schrodinger equation is correct and credible. From this investigation we can not only solve difficulties and problems disputed for about a century by plenty of scientists in quantum mechanics but also promote the development of physics and enhance the knowledge and recognition levels to the essences of microscopic matter.
文摘Black pepper (Piper nigrum L.) is an extensively used medicinal plant in Ayurvedic medicine since ancient times. Here we present Fourier transform infrared (FT-IR) and Fourier transform Raman (FT-Raman) spectra of black pepper powder, which reveal the presence of some specific functional groups, attributed to the different vibrational bands present. Through the assignment of the vibrational bands, black pepper is shown to have enough carboxyl dimer character, a feature that could make it effective in the treatment of the deadly disease vitiligo. Mineral composition reported with the help of XRF spectra strengthens this.
文摘The RAX series paraxylene (PX) adsorbents RAX-2000A and RAX-3000, are developed by the Sinopec Re- search Institute of Petroleum Processing (RIPP) and manufactured by the Sinopec Catalyst Company. Performance test of RAX-2000A showed that the average purity of the PX product reached 99.81%, with an average PX yield of 98.6% per pass. The new generation of PX adsorbents, RAX-3000 not only retains most advantages of the adsorbent RAX-2000A, but also has higher selective adsorption capacity by at least 8%. The actual unit production capability of the adsorbent RAX- 3000 was increased by about 18%. The RAX series PX adsorbents exhibited good adaptability to unfavorable feedstock containing high ethyl benzene (EB) fraction besides their better mechanical strength. Preliminary test results indicated that compared to the adsorbent RAX-2000A, the A/Fa and D/F relating to the adsorbent RAX-3000 were notably decreased due to the hi^her selective adsorotion canacitv of the adsorbent RAX-3000.
文摘This paper applies fuzzy logic approach to examine consumer ethnocentrism level for Jordanians based on their socio-psychological variables namely, patriotism, nationalism and internationalism. To model the relationships between three inputs namely, patriotism, nationalism and internationalism and one output ethnocentrism MATLAB ANFIS has been used, utilizing a sample of 341 Jordanians live in Amman city. Results indicate that fuzzy logic model can predict correctly consumers ethnocentric tendencies knowing their patriotic, nationalistic and internationalist feelings. Fuzzy logic approach shows that high level of nationalism leads consumers to be ethnocentric.