浅谈思想政治课的学法指导

在初中政治课的教学中，实施素质教育重视对学生学习能力的培养，要变学生被动学习为主动学习，充分发挥学生的主观能动性，实现政治课教学的良好效果，教师应重视对学生学习方法的指导。从而为今后学生的学习夯实基础，为学生终身学习提供条件。

Non-isothermal thermal decomposition kinetics of high iron gibbsite ore based on Popescu method

The thermal decomposition kinetics of high iron gibbsite ore was investigated under non-isothermal conditions.Popescu method was applied to analyzing the thermal decomposition mechanism.The results show that the most probable thermal decomposition mechanism is the three-dimensional diffusion model of Jander equation,and the mechanism code is D3.The activation energy and pre-exponential factor for thermal decomposition of high iron gibbsite ore calculated by the Popescu method are 75.36 kJ/mol and 1.51×10-5 s-（-1）,respectively.The correctness of the obtained mechanism function is validated by the activation energy acquired by the iso-conversional method.Popescu method is a rational and reliable method for the analysis of the thermal decomposition mechanism of high iron gibbsite ore.

语文课堂教学模式改革之我见

0引言课堂教学是实施素质教育的主要阵地,实践能力和创新精神的培养,应该首先从课堂教学予以突破。在教学实践中,课堂的低效能教学,容易导致学生厌学、课堂违规违纪。高效课堂是促进教师专业化发展和学生全面发展的有效途径,是提高教育教学质量的现实要求。如何提高其效率,就成为被一个突出的问题。我解决这个这个问题的指导思想是:抓根固本,教师少讲、精讲,学生多读、多练。具体做法如下:1优化教学目标教学目标是教与学的努力目标,也是组织教学、测试命题、质量评价的依据。因为有效的教和有效的学开始于准确地知道希望达到的目标是什么。教学目标在教学过程中具有导向、调控、评价、激励功能。我们在拟定教学目标时,依据大纲,紧扣教材,做到三个突出:突出字、词、句、点(标点);突出听、说、读、写;突出知、情、意、行。

《教育实践与研究》“课程标准实施、校本课程实践与教师专业发展”征文启事

为切实贯彻落实国家中长期教育改革和发展规划纲要,切实贯彻落实全国教育工作会议精神,推进课程标准实施和课程改革实践,总结经验,进一步提升相关理论水平和理念境界,提高教师的实践与研究水平,经研究,本刊编辑部特组织"课程标准实施。

《教育实践与研究》“课程标准实施、校本课程实践与教师专业发展”征文启事

为切实贯彻落实国家中长期教育改革和发展规划纲要,切实贯彻落实全国教育工作会议精神,推进课程标准实施和课程改革实践,总结经验,进一步提升相关理论水平和理念境界,提高教师的实践与研究水平,经研究,本刊编辑部特组织"课程标准实施、课程改革实践与教师专业发展"专题征文与评选活动。

《教育实践与研究》“课程标准实施、校本课程实践与教师专业发展”征文启事

为切实贯彻落实国家中长期教育改革和发展规划纲要,切实贯彻落实全国教育工作会议精神,推进课程标准实施和课程改革实践,总结经验,进一步提升相关理论水平和理念境界,提高教师的实践与研究水平,经研究,本刊编辑部特组织"课程标准实施、课程改革实践与教师专业发展"专题征文与评选活动。

Simulation study on non-linear effects of initial melt temperatures on microstructures during solidification process of liquid Mg_7Zn_3 alloy

The non-linear effects of different initial melt temperatures on the microstructure evolution during the solidification process of liquid Mg7Zn3 alloys were investigated by molecular dynamics simulation, The microstructure transformation mechanisms were analyzed by several methods. The system was found to be solidified into amorphous structures from different initial melt temperatures at the same cooling rate of 1×10^12 K/s, and the 1551 bond-type and the icosahedron basic cluster （12 0 12 0 ） played a key role in the microstructure transition. Different initial melt temperatures had significant effects on the final microstructures. These effects only can be clearly observed below the glass transition temperature Tg; and these effects are non-linearly related to the initial melt temperatures, and fluctuated in a certain range. However, the changes of the average atomic energy of the systems are still linearly related with the initial melt temperatures, namely, the higher the initial melt temperature is, the more stable the amorphous structure is and the stronger the glass forming ability will be.

Chromatographic fingerprint analysis of Fructus Aurantii Immaturus by HPLC-DAD and chemometric methods

An efficient method for quality control of Fructus Aurantii Immaturus (FAI),a famous traditional Chinese medicine (TCM) was established. A simple and reliable high-performance liquid chromatography-photodiode array detector (HPLC-DAD) procedure coupled with chemometric methods was developed for fingerprint analysis,qualitative analysis and quantitative determination of this herb. In qualitative and quantitative analyses,heuristic evolving latent projection (HELP) method was employed to resolve the overlapping peaks of the tested samples. Two bioactive components,namely hesperidin and naringin,are confirmed and determined,together with four flavonoids compounds tentatively identified including two new ones. From fingerprint analysis,the fingerprint data were processed with correlation coefficients for quantitative expression of their similarity and dissimilarity. The developed method based on an integration of chromatographic fingerprint and quantitative analysis is scientific,and the obtained results can be applied to the quality control of herb medicine.

The expression of Elf-1 and Ki-67 and their correlations in non-small-cell lung cancer

Objective: Elf-1 is a member of the proto-oncogenes Ets-related transcription factor family and over-expressed in many human tumors, Ki-67 is an important nuclear antigen associated with cell proliferation. This study investigated the expression of Elf-1 and Ki-67 in non-small-cell lung cancer(NSCLC) and studied their correlation with the clinicopathological features. Methods: Tissue microarray from 64 cases lung cancer tissue and 10 cases normal lung tissue was constructed, immunohistochemical method was used to evaluate the protein expressions of Elf-1 and Ki-67, correlations of the expression of Elf-1 and Ki-67 to clinicopathological features of NSCLC were analyzed. Results: Expression of Elf-1 and Ki-67 in NSCLC tissues were significantly higher than in normal lung tissues(P < 0.05), the positive rate of Elf-1 and Ki-67 was 73.44% and 64.06% in NSCLC group, Overexpression of Elf-1 in NSCLC was significantly related to histopathological grading, different clinical staging and the intensity of ELF-1 expression was significantly higher in the group with lymph node metastasis than that without(P < 0.05). Overexpression of Ki-67 was also closely related to tumor differentiation, clinical stages and lymph node metastasis(P < 0.05). In addition positive correlation was found between the expressive intensity of Elf-1 and Ki-67(τ = 0.295, P = 0.018). Conclusion: The high expression and positive correlation of Elf-1 and Ki-67 in NSCLC suggest that they probably play a role in onset and progression of lung cancer, united detecting their expression could be used as an valuable molecular biological index for predicting the malignant behavior and early diagnosis of NSCLC.

Isolation and Characterization of Phosphate-Solubilizing Bacteria from Seagrass Rhizosphere Soil

Phosphate-solubilizing bacterial strains(6 Nos.) were isolated from the rhizosphere soils of two seagrasses(Halophila ovalis(R.Br.) Hook and Halodule pinifolia(Miki) Hartog) in the Vellar estuary.Experimental studies found that the strain PSSG6 was effective in phosphate solubilization with Phosphate Solubilization efficiency index E = 375 ± 8.54,followed by the strain PSSG5 with Phosphate Solubilization efficiency index E = 275 ± 27.3.Of the 6 strains isolated,the strains PSSG4 and PSSG5 be-longed to the genus Bacillus,and PSSG1,PSSG2 and PSSG3 were identified as Citrobacter sp.,Shigella sp.,and Klebsiella sp.,respectively,by conventional method,and PSSG6 was identified as Bacillus circulans using conventional and molecular methods.

Reflections on Basic Skill Training in Piano Teaching

By analyzing several effective finger practices, it is possible to consolidate the basic skills to help students adjust and establish a good touch mode. This is an important pre-requisite for pursuing strength and speed during playing. The training method can be targeted to solve some common problems, and guide students to consciously feel the touch and the change of tone, listening with ears, controlling with fingers to achieve solid and soft balanced unity.

Discrete element method of improved performance of railway ballast bed using elastic sleeper

With the development of high-speed and heavy-haul railway in China, problems like insufficient thickness of ballast bed and overlarge track stiffness are obvious. Ballast may break into small particles and their contact status will deteriorate under cyclic loading, resulting in ballast degradation. Discrete element method(DEM) was used to research improved performance of ballast bed using elastic sleeper. Clusters were generated by bonding spheres to model real ballasts, while broken bonds were utilized to distinguish breakage. Two kinds of ballast beds with elastic sleeper and conventional sleeper were established, respectively. After applying cyclic loading to the models, differences of mechanical properties between two models were analyzed by contrasting their dynamic behavior indexes, such as particle contact force, sleeper settlement, vibration velocity and acceleration, breakage characteristic. The results illustrate that compared with conventional sleeper, elastic sleeper increases sleeper settlement, while reduces ballast vibration and contact force between particles, which could depress ballast breakage.

A new approach of extracting vegetation points from urban airborne LiDAR data

Urban vegetation has been an important indicator for the evaluation of eco-cities, which is of great significance to promote eeo-city construction. We study and discuss the commonly used urban vegetation extrac-tion methods. The extraction of vegetation points in this study is completed through mathematical statistics, mean-square error, successive differences and iterative algorithm which are based on the analysis of different spatial morphological characteristics in urban point clouds. Linyi, a city of Shandong Province in China, is se-lected as the study area to test this method and the result shows that the proposed method has a strong practicali- ty in urban vegetation point cloud extraction. Only 3D coordinate properties of the LiDAR point clouds are used in this method and it does not require additional information, for instance, return intensity, which makes the method more applicable and operable.

A hybrid method for extraction of protein-protein interactions from literature

In this work, a hybrid method is proposed to eliminate the limitations of traditional protein-protein interactions （PPIs） extraction methods, such as pattern learning and machine learning. Each sentence from the biomedical literature containing a protein pair describes a PPI which is predicted by first learning syntax patterns typical of PPIs from training corpus and then using their presence as features, along with bag-of-word features in a maximum entropy model. Tested on the BioCreAtIve corpus, the PPIs extraction method, which achieved a precision rate of 64%, recall rate of 60%, improved the performance in terms of F1 value by 11% compared with the component pure pattern- based and bag-of-word methods. The results on this test set were also compared with other three extraction methods and found to improve the performance remarkably.

Related factors of dilated cardiomyopathy

Objective To investigate the etiology and relative factors of dilated cardiomyopathy （DCM） in Chinese patients. Methods A case-control study was conducted to compare 233 patients with DCM in high-incidence areas （case group） and 150 patients with stable angina pectoris （control group）. Life styles and history of diseases information was collected by questionaire; human anti-myocardial antibody lgG （AMA- IgG）, human Coxsackie B virus IgG （CBV- IgG） and human adenovirus antibody IgG （ADV- IgG） were measured with ELISA. General chemical and toxicological indicators in drink water from high and low prevalence areas and serum trace elements also were compared. Results 1） Compared with the control group, the case group had more farmers （P 〈 0.01）, with low average incomes （P 〈 0.01 ）, higher alcohol consumption （P 〈 0.01） and higher incidence of the history of myocarditis （P 〈 0.01）. 2） AMA-IgG, CBV-IgG and ADV-IgG levels were low and the positive rates ofAMA-IgG, CBV-IgG and ADV-IgG of patients with DCM were respectively 7.78%, 6.67% and 6.67%, no statistical significance comparing with those in the control group. 3） The content of iron （1.36±2.18 vs 0.39±0.67 rag/L, P〈0.05） and manganese （0.38±0.35 vs 0.15±0.14, P〈0.01） in drinking water of high-incidence areas was significantly higher than that in low-incidence areas. 4） The content of serum iron （69.1±57.8 vs 20.0±17.5 umol/L, P〈0.01 ） and copper （25.7±4.2 vs 19.7±4.5 umol/L, P〈0.01） in the case group evidently exceeded the normal range and obviously higher than that in the control group. Conclusions 1） The incidence of some DCM is related with low incomes, high alcohol consumption and myoearditis. 2） These data do not support that DCM is related with persistent virus infection and autoimmunization; 3） Iron and manganese contents exceeding standards in drinking water and the high content of serum iron and copper is comparatively related with the incidence of DCM.

The Internal Logic Between the Inclusive Financial System Development and Poverty Reduction

This paper introduces the origin of Inclusive Financial System, summarizes the basic theories and views on inclusive financial system development and poverty reduction from experts and scholars at home and abroad. The paper establishes a theoretical analysis framework which impacts poor family income gap by using exponential smoothing method. The government should improve the credit market in poverty- stricken area by the way of macro-management to establish inclusive financial system, to overcome the difficulty of poor farmers＇ credit, to make more poor families to obtain credit opportunities.

Kinetic Study of Color Changes of Tomato Purees with Microwave and Conventional Drying

Kinetics of color change in tomato purees dried using microwave and conventional method were investigated. For this purpose, the color parameters of Hunter L,a,b and browning index （A42o）, and estimated values of chroma, hue angle, AE, Hunter a/b and a ~ b were examined. The changes in color of tomato samples followed both zero and first order kinetic models to describe visual color changes, and ＆E parameters followed first order kinetic. It was concluded that Hunter axb parameters can be used adequately to follow up the color change of tomato samples during the drying.

Chemical fingerprinting of Su-He-Xiang-Wan and attribution of major characteristic peaks for its quality control by GC-MS

A simple and facile gas chromatography-mass spectrometer （GC-MS） fingerprint of Su-He-Xiang-Wan （SHXW） was developed, the similarity analysis was conducted, and attribution of the major characteristic peaks was identified for SHXW quality control. GC-MS analysis was performed on a QP2010 instrument （Shimadzu, Japan） equipped with a capillary column of RTX-5MS. The column temperature was initiated at 50℃, held for 5 min, increased at the rate of 3 ℃/min to 120 ℃, held for 2 min, and then increased at the rate of 4 ℃/min to 220℃, held for 10 min. Helium carrier gas was used at a constant flow rate of 1.3 mL/min. Mass conditions were ionization voltage, 70 eV; injector temperature, 250℃; ion source temperature, 250 ℃; splitting ratio, 30：1; full scan mode in the 40-500 Da mass ranges with rate of 0.2 s per scan. Attribution of the major characteristic peaks was identified for SHXW by comparing the chemical standards, references of Chinese herbal medicines and the negative controls of prescription samples （NC） of SHXW. With the help of the temperature-programmed retention indices （PTRIs） used together with mass spectra and chemical standards, 25 major characteristic peaks have been identified. Nine volatile medicinal materials were identified in the prescription of SHXW by attributing to the 27 major characteristic peaks. The results demonstrate that the proposed method is a powerful approach to quality control of complex herbal medicines.

The Hemochromatosis Distribution in Matera Province： A New SNP to Explain the Low Genotype-Phenotype Correlation

The present study aims to investigate the genotype-phenotype correlation of the hereditary hemochromatosis （HH）, a genetic disorder of iron metabolism, in Matera province （Basilicata, Italy）. Integrating both epidemiological and molecular approaches, the authors studied： （a） the frequency of the HH main mutations; （b） the association between mutations and HH cases. The majority of patients with HH are homozygous for the C282Y mutation of the HFE gene. A second mutation （H63D） is more widely distributed and its connection with HH isn＇t clear, but a low penetrance is attributed to this variant. The population-based study consists of three steps： （1） determination of iron biochemical parameters, （2） genetic test, and （3） sequencing of HFE gene and bioinformatics studies. A case report is presented in a 41-year-old male （genotype： H63D/wt） with biochemical and clinical evidences of HH, in absence of secondary iron overload factors. In the cohort of studied patients （150M：62F）, there are 18 homozygous patients; H63D/H63D genotype is found in 11 cases. In the heterozygous group, H63D/wt is the predominant genotype （61/68 subjects）. All the H63D/wt residents in the same village （Mont.） show altered biochemical parameter levels. In our case study, a substitution localized into the HFE promoter （nt225A 〉 C） is found. Results show that the H63D genotype is responsible for most cases of HH. The peculiar clinical manifestation found in Mont. suggests a founder effect. In our case, the iron overload is related to a presence of an undetected mutation, critical for the transcriptional regulation of the HFE gene.

谈小学生自学能力的培养

苏霍姆林斯基认为:"在小学阶段面临许多的任务中,首要的就是教会学生学习"。教师注重并抓实学生的自学能力的培养,使之养成自学的习惯,获得学习的主动权,是现代教育发展的需要,是学生终生发转的需要。一、自学能力的概念界定自学,是指学习者独立的学习活动。在学校教学中的自学,