Objective This work summarizes the clinical features and treatment of 10 AIDS patients with malignant lymphoma. Methods A total of 10 AIDS patients with malignant lymphoma seen in Beijing Ditan Hospital since 2009 wer...Objective This work summarizes the clinical features and treatment of 10 AIDS patients with malignant lymphoma. Methods A total of 10 AIDS patients with malignant lymphoma seen in Beijing Ditan Hospital since 2009 were enrolled. Clinical manifestations, pathological examinations, immunity levels, Epstein-Barr virus antibody examinations, complications, treatments, and outcomes were retrospectively analyzed. Results The main clinical manifestations of these patients included intermittent fever in 2 cases, neck masses and fever in 3 cases, auxiliary lymph node enlargement in 2 cases, and abdominal pain and bloating with fever in 3 cases. Up to 7 patients were pathologically diagnosed with diffuse large B cell lymphoma (DLBCL), and 3 patients were pathologically diagnosed with Burkitt's lymphoma. Up to 8 patients had CD4 cell counts below 200/μL, and 2 patients had a level of more than 200/μL. Up to 7 patients were negative for EBV-IgM antibodies and 3 patients were not examined. Six patients underwent different chemotherapy and their prognoses were different. One patient with Burkitt's lymphoma alternatively took CODOXM and IVAC for 3 turns after VP chemotherapy; 1 patient with liver metastasis took R-CHOP 5 times, then changed therapy regimen to R-MINE and MINE. One patient with adrenal DLBCL took CHOP 6 times. Three patients with DLBCL took CHOP 1 or 2 times. Four patients gave up treatment. Various infections and side effects occurred, including bone marrow suppression, gastrointestinal bleeding, and renal dysfunction during chemotherapy. Six patients took HAARI, and 4 did not. Six patients died, whereas 3 patients got improved; and 1 patient was discharged. Conclusions AIDS patients with malignant lymphoma had various clinical manifestations, were immunocompromised, and had multiple metastases when they were admitted; they were already in the interim or late stage of lymphoma. Chemotherapy was not effective, and additional complications occurred. HAART failed to improve patient prognosis, and the overall prognosis was poor.展开更多
Gingival adenoid cystic carcinoma (ACC) is a rare malignancy. We describe the diagnosis and treatment of a 43 year- old woman who presented with a persistent oral ulcer for approximately 1 year, and subsequent pain in...Gingival adenoid cystic carcinoma (ACC) is a rare malignancy. We describe the diagnosis and treatment of a 43 year- old woman who presented with a persistent oral ulcer for approximately 1 year, and subsequent pain in the left posterior maxillary region. Clinical examination revealed an ulcer in the left upper molar gingiva, with swelling in the region from the second premolar to the third molar. X-ray images demonstrated the involvement of the maxillary alveolar bone. The histopathological and immunohistochemical features were diagnostic of ACC. ACC is often presented as a gingival lesion; thus, it may easily be neglected by patients. The identification of this tumor using specific pathological analyses prevents misdiagnosis and enables clinicians to determine the appropriate treatment. In this case, no recurrence or distant metastasis was observed after 2 years of follow-up.展开更多
This paper analyzes of the bottleneck to influence the running efficiency of educational administration system in universities and colleges,and from the system deployment architecture, server configuration, database S...This paper analyzes of the bottleneck to influence the running efficiency of educational administration system in universities and colleges,and from the system deployment architecture, server configuration, database SQL statement optimization and other aspects, it puts forwards the optimization scheme.展开更多
In this paper, we present Real-Time Flow Filter (RTFF) -a system that adopts a middle ground between coarse-grained volume anomaly detection and deep packet inspection. RTFF was designed with the goal of scaling to hi...In this paper, we present Real-Time Flow Filter (RTFF) -a system that adopts a middle ground between coarse-grained volume anomaly detection and deep packet inspection. RTFF was designed with the goal of scaling to high volume data feeds that are common in large Tier-1 ISP networks and providing rich, timely information on observed attacks. It is a software solution that is designed to run on off-the-shelf hardware platforms and incorporates a scalable data processing architecture along with lightweight analysis algorithms that make it suitable for deployment in large networks. RTFF also makes use of state of the art machine learning algorithms to construct attack models that can be used to detect as well as predict attacks.展开更多
Escalation of commitment has been linked to losses in information systems (IS) projects. Understanding the nature and the rationality of escalation allows the firm to promote optimal project management practices. Th...Escalation of commitment has been linked to losses in information systems (IS) projects. Understanding the nature and the rationality of escalation allows the firm to promote optimal project management practices. This study takes an inter-disciplinary approach and draws on research from economics and management to create a model of irrational escalation and a model of rational escalation. The forces that contribute to irrational escalation include the responsibility of the same manager for both the project selection and project continuation decisions that create proneness to self-justification, the potential for negative framing of decision options due to large sunk costs, the proximity of project completion and the presence of organizational inertia. Identifying these irrational escalation factors helps design appropriate de-escalation techniques. The rational escalation model draws on the real option theory and the bandit process theory to identify conditions when project continuation is justified by the value of information and the value of flexibility that the firm receives from continuing the project.展开更多
In recent years, with the development of quantum cryptography, quantum signature has also made great achievement. However,the effectiveness of all the quantum signature schemes reported in the literature can only be v...In recent years, with the development of quantum cryptography, quantum signature has also made great achievement. However,the effectiveness of all the quantum signature schemes reported in the literature can only be verified by a designated person.Therefore, its wide applications are limited. For solving this problem, a new quantum proxy signature scheme using EPR quantumentanglement state and unitary transformation to generate proxy signature is presented. Proxy signer announces his public key whenhe generates the final signature. According to the property of unitary transformation and quantum one-way function, everyone canverify whether the signature is effective or not by the public key. So the quantum proxy signature scheme in our paper can be publicverified. The quantum key distribution and one-time pad encryption algorithm guarantee the unconditional security of this scheme.Analysis results show that this new scheme satisfies strong non-counterfeit and strong non-disavowal.展开更多
基金supported by a grant from the Major Scientific Projects of the National Eleventh Five-year Special Planning in Prevention and Treatment of Main Infectious Diseases, such as AIDS and Viral Hepatitis(No.2008ZX10001-006)
文摘Objective This work summarizes the clinical features and treatment of 10 AIDS patients with malignant lymphoma. Methods A total of 10 AIDS patients with malignant lymphoma seen in Beijing Ditan Hospital since 2009 were enrolled. Clinical manifestations, pathological examinations, immunity levels, Epstein-Barr virus antibody examinations, complications, treatments, and outcomes were retrospectively analyzed. Results The main clinical manifestations of these patients included intermittent fever in 2 cases, neck masses and fever in 3 cases, auxiliary lymph node enlargement in 2 cases, and abdominal pain and bloating with fever in 3 cases. Up to 7 patients were pathologically diagnosed with diffuse large B cell lymphoma (DLBCL), and 3 patients were pathologically diagnosed with Burkitt's lymphoma. Up to 8 patients had CD4 cell counts below 200/μL, and 2 patients had a level of more than 200/μL. Up to 7 patients were negative for EBV-IgM antibodies and 3 patients were not examined. Six patients underwent different chemotherapy and their prognoses were different. One patient with Burkitt's lymphoma alternatively took CODOXM and IVAC for 3 turns after VP chemotherapy; 1 patient with liver metastasis took R-CHOP 5 times, then changed therapy regimen to R-MINE and MINE. One patient with adrenal DLBCL took CHOP 6 times. Three patients with DLBCL took CHOP 1 or 2 times. Four patients gave up treatment. Various infections and side effects occurred, including bone marrow suppression, gastrointestinal bleeding, and renal dysfunction during chemotherapy. Six patients took HAARI, and 4 did not. Six patients died, whereas 3 patients got improved; and 1 patient was discharged. Conclusions AIDS patients with malignant lymphoma had various clinical manifestations, were immunocompromised, and had multiple metastases when they were admitted; they were already in the interim or late stage of lymphoma. Chemotherapy was not effective, and additional complications occurred. HAART failed to improve patient prognosis, and the overall prognosis was poor.
文摘Gingival adenoid cystic carcinoma (ACC) is a rare malignancy. We describe the diagnosis and treatment of a 43 year- old woman who presented with a persistent oral ulcer for approximately 1 year, and subsequent pain in the left posterior maxillary region. Clinical examination revealed an ulcer in the left upper molar gingiva, with swelling in the region from the second premolar to the third molar. X-ray images demonstrated the involvement of the maxillary alveolar bone. The histopathological and immunohistochemical features were diagnostic of ACC. ACC is often presented as a gingival lesion; thus, it may easily be neglected by patients. The identification of this tumor using specific pathological analyses prevents misdiagnosis and enables clinicians to determine the appropriate treatment. In this case, no recurrence or distant metastasis was observed after 2 years of follow-up.
基金Acknowledgement Research of the nature science foundation of Shandong province has a triangular surface modeling and control display representation(No. ZR2012FL05)
文摘This paper analyzes of the bottleneck to influence the running efficiency of educational administration system in universities and colleges,and from the system deployment architecture, server configuration, database SQL statement optimization and other aspects, it puts forwards the optimization scheme.
文摘In this paper, we present Real-Time Flow Filter (RTFF) -a system that adopts a middle ground between coarse-grained volume anomaly detection and deep packet inspection. RTFF was designed with the goal of scaling to high volume data feeds that are common in large Tier-1 ISP networks and providing rich, timely information on observed attacks. It is a software solution that is designed to run on off-the-shelf hardware platforms and incorporates a scalable data processing architecture along with lightweight analysis algorithms that make it suitable for deployment in large networks. RTFF also makes use of state of the art machine learning algorithms to construct attack models that can be used to detect as well as predict attacks.
文摘Escalation of commitment has been linked to losses in information systems (IS) projects. Understanding the nature and the rationality of escalation allows the firm to promote optimal project management practices. This study takes an inter-disciplinary approach and draws on research from economics and management to create a model of irrational escalation and a model of rational escalation. The forces that contribute to irrational escalation include the responsibility of the same manager for both the project selection and project continuation decisions that create proneness to self-justification, the potential for negative framing of decision options due to large sunk costs, the proximity of project completion and the presence of organizational inertia. Identifying these irrational escalation factors helps design appropriate de-escalation techniques. The rational escalation model draws on the real option theory and the bandit process theory to identify conditions when project continuation is justified by the value of information and the value of flexibility that the firm receives from continuing the project.
基金supported by the National Science and Technology Key Project (Grant No. 2010ZX03003-003-01)the National Basic Research Program of China (Grant No. 2007CB311203)
文摘In recent years, with the development of quantum cryptography, quantum signature has also made great achievement. However,the effectiveness of all the quantum signature schemes reported in the literature can only be verified by a designated person.Therefore, its wide applications are limited. For solving this problem, a new quantum proxy signature scheme using EPR quantumentanglement state and unitary transformation to generate proxy signature is presented. Proxy signer announces his public key whenhe generates the final signature. According to the property of unitary transformation and quantum one-way function, everyone canverify whether the signature is effective or not by the public key. So the quantum proxy signature scheme in our paper can be publicverified. The quantum key distribution and one-time pad encryption algorithm guarantee the unconditional security of this scheme.Analysis results show that this new scheme satisfies strong non-counterfeit and strong non-disavowal.