大美育视野下的书法文化价值刍议

当前书法面临着一个难得的发展机遇,它在国家文化发展战略中的重要性日益凸显。深入研究书法的社会文化价值,具有学术性与现实性的双重意义。本文从大美育的视野出发,结合高等院校书法专业的课程设置情况,探讨与之相关的文化身份、守"正"与书法的气象以及学书综合能力的培育这三个问题,旨在阐明书法教育对于当代美育的价值与作用。

Is ERCP really necessary in case of suspected spontaneous passage of bile duct stones?

AIM:To investigate the usefulness of magnetic resonance cholangiopancreatography (MRCP) and the need for endoscopic retrograde cholangiopancreatography (ERCP) in cases of suspected spontaneous passage of stones into the common bile duct.METHODS:Thirty-six patients with gallbladder stones were clinically suspected of spontaneous passage of stones into the common bile duct because they presented with clinical symptoms such as abdominal pain and fever,and showed signs of inflammatory reaction and marked rise of hepatobiliary enzymes.These symptoms resolved and they showed normalized values of blood biochemical parameters after conservative treatment without evidence of stones in the common bile duct on MRCP.All these patients were subjected to ERCP within 3 d of MRCP to check for the presence of stones.RESULTS:No stones were detected by ERCP in any patient,confi rming the results of MRCP.CONCLUSION:When clinical symptoms improve,blood biochemical parameters have normalized,and MRCP shows there are no stones in the common bile duct,it can be considered the stone has spontaneously passed and thus ERCP is not necessary.

The Automorphism Group of the Lie Group T（D（V_N,F））

In this paper,the authors determine maximal connected automorphism group of the Lie transformation group T（D（VN,F））,which acting on the normal Siegel domain D（VN,F）is simple and transitive,and prove that the maximal connected automorphism group of T（D（VN,F））is its maximal connected inner automorphism group.

Correction to Hawking Tunneling Radiation from Global Monopole Charged BlackHole

Considering the self-gravitation and energy conservation as well as charge conservation, we extend Medved and Vagenas＇s quantum tunneling method to the global monopole charged black hole, and give a correction to Hawking radiation of a charged particle.

Optimized extraction and purification technology of Gekko sulfated glycopeptide based on its anticancer activities

Objective:To optimize the extraction and purification technologies of Gekko sulfated glycopeptide based on the content of glycopeptide,removal ratio of proteins,and anticancer activities.Methods:Different extraction methods,namely,water extraction,ultrasonic extraction,enzymatic hydrolysis-water extraction,and enzymatic hydrolysis-ultrasonic extraction were considered to determine the best extraction method.Single factor and orthogonal experiments were performed to determine the optimum extracting conditions.Sevage,enzymatic hydrolysis-Sevage,trichloroacetic acid(TCA),TCA-Sevage and enzymatic hydrolysis-TCA methods were tested to determine the best deproteinization method.The glycopeptide content and protein removal ratio were analyzed by the phenol-sulfuric acid and Coomassie Brilliant Blue methods.Results:Gekko sulfated glycopeptide obtained by water extraction could inhibit the proliferation of HepG2 and SKBR3,as well as promote that of lymphocytes.The glycopeptide content was 4.049%in the optimal extracting condition of a triple decoction extraction for 1 hour each time with a material to solvent ratio of 1:15.The enzymatic hydrolysis-TCA method was found to be the optimal deproteinization method,with a protein removal ratio of 50.46%,glycopeptide content of 14.27%,and inhibitory ratio on human HepG2 cells of 49.06%.Conclusion:This extraction and purification technique for Gekko sulfated glycopeptide is reasonable,feasible,and provides a scientific basis for industrial production.

GENERALIZED ENERGY CONSERVATION AND UNSTABLE PERTURBATION PROPERTY IN BAROTROPIC VORTEX

Based on a barotropic vortex model, generalized energy-conserving equation was derived and twonecessary conditions of basic flow destabilization are gained. These conditions correspond to generalizedbarotropic instability and super speed instability. They are instabilities of vortex and gravity inertial waverespectively. In order to relate to practical situation, a barotropic vortex was analyzed, the basic flow of which issimilar to lower level basic wind field of tropical cyclones and the maximum wind radius of which is 500 km.The results show that generalized barotropic instability depending upon the radial gradient of relative vorticitycan appear in this vortex. It can be concluded that unstable vortex Rossby wave may appear in barotropic vortex.

COMPARISON OF ON-LINE COUPLED AND CONSTANT TRANSFER SIMULATION METHODS FOR DIRECT RADIATIVE FORCING OF ANTHROPOGENIC SULFATE

1 INTRODUCTION Of three main methods for studying the radiative forcing of anthropogenic sulfate and climatic response on the regional scale, the first is, with given rates for transforming SO2 to sulfate, converting actually released SO2 into sulfate and acquiring the distribution of sulfate by computing transfer equations in the climate model. The second is obtaining the sulfate distribution through chemical reaction and transfer of matters in regional climate models online coupled with an atmospheric chemistry model that includes full chemical reactions for sulfides. The third is to put sulfate distribution data from GCM and its coupled atmospheric chemistry model to regional climate model, which is so called off-line coupled method. As shown in comparisons between the online and offline modeling on the regional scale, the radiative climate effect of sulfate shows large uncertainty due to significant influence from various methods.

Rare horizontal transmission does not hide long-term inheritance of SINE highly conserved domains in the metazoan evolution

Transposable elements （TEs） are self-replicating, mobile DNA sequences which constitute a significant fraction of eukaryotic genomes. They are generally considered selfish DNA, as their replication and random insertion may have deleterious effects on genome functionalities, although some beneficial effects and evolutionary potential have been recognized. Short interspersed elements （SINEs） are non-autonomous TEs with a modular structure： a small RNA-related head, a body, and a long interspersed element-related tail. Despite their high turnover rate and de novo emergence, the body may retain highly conserved domains （HCDs） shared among divergent SINE families： in metazoans, at least nine HCD-SINEs have been recognized. Data mining on public molecular databases allowed the retrieval of 16 new HCD-SINE families from cnidarian, molluscs, arthropods, and vertebrates. Tracking the ancestry of HCDs on the metazoan phylogeny revealed that some of them date back to the Radiata-Bilateria split. Moreover, phylogenetic and age versus divergence analyses of the most ancient HCDs suggested that long-term vertical inheritance is the rule, with few horizontal transfer events. We suggest that the evolutionary conservation of HCDs may be linked to their potential to serve as recombination hotspots. This indirectly affects host genomes by maintaining active and diverse SINE lineages, whose insertions may impact （either positively or negatively） on the evolution of the genome.