大采高综采工作面安全高效回撤工艺浅析

针对采高较大的综采工作面支架安全回撤,山西马堡煤业有限公司采用单轨吊机车配合出架装置,摒弃以往综采工作面回撤用绞车生拉硬拽的不安全方式,实现了安全高效的机械化回撤。既缩短了续接工作面搬家的时间,降低了人工劳动强度,又大大提高了安全系数,为同类条件下大采高综采工作面支架的安全高效回撤提供了经验,对煤矿生产具有借鉴意义。

“三软”煤层煤巷掘进超前注盐水的研究与实施

嵩山煤矿在"三软"煤层中为克服煤层胶结度低、易粉碎,煤巷压力大、来压快的不利条件,通过研究与实施煤巷掘进超前注盐水工艺,成功地实现了安全、高效掘进煤巷的目标。

ENERGY EFFICIENT DISTRIBUTED STEGANOGRAPHY FOR SECURE COMMUNICATION IN WIRELESS MULTIMEDIA SENSOR NETWORKS

A secure communication mechanism is necessary in the applications of Wireless Multimedia Sensor Networks (WMSNs), which is more vulnerable to security attacks due to the presence of multimedia data. Additionally, given the limited technological resources (in term of energy, computation, bandwidth, and storage) of sensor nodes, security and privacy policies have to be combined with energy-aware algorithms and distributed processing of multimedia contents in WMSNs. To solve these problems in this paper, an energy efficient distributed steganography scheme, which combines steganography technique with the concept of distributed computing, is proposed for secure communication in WMSNs. The simulation results show that the proposed method can achieve considerable energy efficiency while assuring the communication security simultaneously.

Chinese herbal medicine for treatment of dislipidemia

Prevalence of dislipidemia is increasing rapidly in China and there has been a growing interest in Chinese herbal medicine for the treatment of hyperlipidemia both inside and outside China. In this article, lipids regulating effects of 9 herbs or their extracts and 5 herbal formulae which have been published in English-language literature are reviewed. Although evidence from animals and humans consistently supports the therapeutic activities of these Chinese herbal medicines, few multi-center large-scale clinical trials have been conducted to confirm the efficacy and evaluate their safety.

料石砌碹斜井井筒起底刷扩施工技术

采用超挖起底技术,井筒自上而下,先起中、后两帮迈步施工,保证料石碹整体性,实现井筒的快速起底刷扩,减少二次出矸,缩短工期。

Efficient Security Sequencing Problem over Insecure Channel Based on Homomorphic Encryption

In the field of sequencing of secret number,an important problem is how to establish an efficient and secure protocol for sorting the secret number.As a powerful tool in solving privacy sequencing problems,secure multipart computation is more and more popular in anonymous voting and online auction.In the present study,related secure computation protocol for sequencing problem is not many by far.In order to improve the efficiency and safety,we propose a security sequencing protocol based on homomorphic encryption.We also give analysis of correctness and security to highlight its feasibility.

Safety and Efficacy of Digoxin TherapymWhere Are We Now？

The aim of our study was to determine the criteria and key factors for the effectiveness of digoxin therapy. A prospective opened-type study was carried out in conditions of everyday clinical practice. The concentrations of digoxin were quantified from blood samples taken following the achievement of drug steady-state （using AxSYM microparticle enzyme immunoassay-MEIA）. The risk/benefit ratio was evaluated based upon the correlation between measured blood concentrations of the drug and clinical response. Study results （100 decompensated patients） revealed that therapy indication field was correctly covered, showing a higher prevalence in elderly. On average, each examinee had 2 or 3 comorbidities. Applied daily dose of digoxin ranged from 0.053 mg to 0.25 mg. Renal function was assessed by creatinine clearance which is one of the key factors for the accomplishment of optimal digoxin serum concentrations （p 〈 0.05）. Co-administration of seven drugs was complicating factor for the management of rational therapy. 76/100 patients were within referent range （0.8-2.0 ng/mL）, while 13/100 were above the upper limit. Four side effects in total were recorded （nausea, vomiting, confusion）, whereas in only two patients digoxin was excluded from the therapy. Digoxin confirmed the justifiability of its use in contemporary clinical practice.

基于无线传感器网络定位技术的图书馆智能管理创新

"互联网+"时代,信息技术的发展对图书馆的智能化管理工作提出了更高的要求。文章概述了无线传感器网络与定位技术,重点讨论了如何将WSN定位技术运用到图书智能管理,通过定位技术与大数据、云计算等信息技术的结合,推动图书馆智能系统建设和智能化发展。

Distributed receding horizon control for fuel-efficient and safe vehicle platooning

This paper investigates the problem of fuel-efficient and safe control of autonomous vehicle platoons. We present a two-part hierarchical control method that can guarantee platoon stability with minimal fuel consumption. The first part vehicle controller is derived in the context of receding horizon optimal control by constructing and solving an optimization problem of overall fuel consumption. The Second part platoon controller is a complementation of the first part, which is given on the basis of platoon stability analysis. The effectiveness of the presented platoon control method is demonstrated by both numerical simulations and experiments with laboratory-scale Arduino cars.

Efficacy and safety of metformin and sitagliptin based triple antihyperglycemic therapy(STRATEGY):a multicenter,randomized,controlled,non-inferiority clinical trial

Despite the current guideline's recommendation of a timely stepwise intensification therapy,the "clinical inertia",termed as the delayed treatment intensification,commonly exists in the real world,which may be partly due to the relatively little substantial evidence and no clear consensus regarding the efficacy and safety of triple oral agents in patients inadequately controlled with dual therapy.In this clinical trial performed in 237 centers in China,5,535 type 2 diabetic patients inadequately controlled by previous therapies were treated with a stable metformin/sitagliptin dual therapy for 20 weeks.The patients who did not reach the glycated hemoglobin A1c(HbA1c) goal were then further randomized into glimepiride,gliclazide,repaglinide,or acarbose group for an additional 24-week triple therapy.A mean HbAlc reduction of 0.85%was observed when sitagliptin was added to the patients inadequately controlled with metformin in 16 weeks.Further HbAlc reductions in the 24-week triple therapy stage were 0.65%in glimepiride group,0.70%in gliclazide group,0.61%in repaglinide group,and 0.45%in acarbose group.The non-inferiority criterion for primary hypotheses was met for gliclazide and repaglinide,but not for acarbose,compared with glimepiride,when added to metformin/sitagliptin dual therapy.The incidences of adverse events(AEs) were 29.2%in the dual therapy stage and30.3%in the triple therapy stage.Metformin/sitagliptin as baseline therapy,with the addition of a third oral antihyperglycemic agent,including glimepiride,gliclazide,repaglinide,or acarbose,was effective,safe and well-tolerated for achieving an HbAlc<7.0%goal in type 2 diabetic patients inadequately controlled with previous therapies.The timely augmentation of up to three oral antihyperglycemic agents is valid and of important clinical benefit to prevent patients from exposure to unnecessarily prolonged hyperglycemia.

Safety of Individual Medication of Ma Qian Zi (Semen Strychni) Based upon Assessment of Therapeutic Effects of Guo's Therapy Against Moderate Fluorosis of Bone

Objective: To assess the safety of individual medication of Guo's Ma Qian Decoction on the basis of effective treatment of fluorosis of bone with Guo's therapy. Methods: One hundred and fourteen cases of moderate fluorosis of bone were randomly divided into a treatment group (n=60) and a control group (n=54) between December 2007 and August 2009 by using the block randomized method and a central random system. At the same time of basic treatment, the patients in the treatment group were orally administrated with Guo's Ma Qian Decoction. The initial dose of Ma Qian Zi (Semen Strychni) was 0.4 g and increased by 0.05 g every two days, with the doses of other drugs unchanged, until the patient had "nux vomica response". For the patients with no "nux vomica response", the dosage was continued to increase and the maximum dosage was not more than 1.2 g/day. The control group was treated with decoction placebo. The changes of strychnine and brucine contents before and after processing and after decoction of Ma Qian Zi (Semen Strychni) were determined with reversed-phase high-performance liquid chromatography, which were controlled within ranges stipulated in the Pharmacopeia; Adverse events were analyzed; Blood strychnine and brucine contents in 10 cases who had taken the drugs were determined. Results: 1) Strychnine (2.125%) and brucine (1.425%) contents before processing of Ma Qian Zi and 1.88% and 1.31% after processing all conformed with the standards of strychnine (1.2-2.2%) and brucine (no less than 0.8%) stipulated in the Pharmacopeia. When the maximum dosage of Ma Qian Zi was 1.2 g/day, strychnine in the decoction was 11.17 mg and brucine was 7.44 mg, which all conformed with the maximum limited amount (strychnine 13.32 and brucine no less than 4.8 mg) stipulated in the Pharmacopeia. 2) Eight cases had "nux vomica response" in the treatment group and one case in the control group, with a significant difference between the two groups (P<0.05). 3) Altogether 18 cases had adverse events, with an incidence rate of 15.38% (8 cases) in the treatment group and 18.52% (10 cases) in the control group, with no difference between the two groups (P>0.05); Among them, 10 cases (8.77%) with the adverse event were not related with therapeutic drugs, with an incidence rate of 6.67% (4 cases) in the treatment and 11.11% (6 cases) in the control group, with no significant difference between the two groups (P>0.05). Seven cases had suspicious relative adverse events, the risk in the treatment group was 0.658 times of the control group, with no significant difference (P>0.05), and one case had the toxic reaction of nux-vomica seed. 4) Strychnine and brucine were unable to be detected in the blood in all points of time in the 10 cases who had taken the drugs, indicating that plasma strychnine and brucine contents were lower than the minimum detectable amount (10 ng), and accumulation of strychnine and brucine were not found in blood of the patient during and after administration for 8 weeks. Conclusion: The individual medication of Ma Qian Zi (Semen Strychni) in the Guo's therapy has a better safety.