AIM: To investigate the effi cacy and safety of rabepra-zole under continuous non-steroidal anti-inflammatory drug (NSAID) administration for NSAID-induced ulcer in Japan. METHODS: Subjects comprised patients undergoi...AIM: To investigate the effi cacy and safety of rabepra-zole under continuous non-steroidal anti-inflammatory drug (NSAID) administration for NSAID-induced ulcer in Japan. METHODS: Subjects comprised patients undergoing NSAID treatment in whom upper gastrointestinal en-doscopy revealed an ulcerous lesion (open ulcer) with diameter ≥ 3 mm, who required continuous NSAID treatment. Endoscopies were performed at the start of treatment, during the treatment period, and at the conclusion (or discontinuation) of treatment. Findings were evaluated as size (maximum diameter) and stage based on the Sakita-Miwa classifi cation. An ulcer was regarded as cured when the "white coating" was seen to have disappeared under endoscopy. As criteria for evaluating safety, all medically untoward symptoms and signs (adverse events, laboratory abnormalities, accidental symptoms, etc.) occurring after the start of rabeprazole treatment were handled as adverse events.RESULTS: Endoscopic cure rate in 38 patients in the efficacy analysis (endoscopic evaluation) was 71.1% (27/38). Among those 38 patients, 35 had gastric ulcer with a cure rate of 71.4% (25/35), and 3 had duodenal ulcer with a cure rate of 66.7% (2/3). Three adverse drug reactions were reported from 64 patients in the safety analysis (interstitial pneumonia, low white blood cell count and pruritus); thus, the incidence rate for adverse drug reactions was 4.7% (3/64).CONCLUSION: The treatment efficacy of rabeprazole for NSAID-induced ulcer under continuous NSAID ad-ministration was confi rmed.展开更多
Two complementary firms' information sharing and security investment are investigated. When two complementary firms with heterogeneous assets are both breached, it is assumed that they suffer different losses which a...Two complementary firms' information sharing and security investment are investigated. When two complementary firms with heterogeneous assets are both breached, it is assumed that they suffer different losses which are associated with their information assets. Some insights about optimal strategies for the firms and the attacker are obtained by the game theory, which forms a comparison with those derived from substitutable firms, and those derived from complementary firms with homogenous loss. In addition, both the unit transform cost of investment and the extent of firms'loss affect the optimal strategies.Assuming that firms can control information sharing, security investments and both of them, respectively, the effect of the social planner is further analyzed on the information sharing, firms' aggregate defence, the aggregate attack and social total cost. Finally, some policy advice is provided through numerical simulation. Results show that firms are willing to choose security investment centrally rather than individually, but an intervention in information sharing by the social planner may not necessarily be preferable.展开更多
Coal mine fires,which can cause heavy casualties,environmental damages and a waste of coal resources,have become a worldwide problem.Aiming at overcoming the drawbacks,such as a low analysis efficiency,poor stability ...Coal mine fires,which can cause heavy casualties,environmental damages and a waste of coal resources,have become a worldwide problem.Aiming at overcoming the drawbacks,such as a low analysis efficiency,poor stability and large monitoring error,of the existing underground coal fire monitoring technology,a novel monitoring system based on non-dispersive infrared(NDIR)spectroscopy is developed.In this study,first,the measurement principle of NDIR sensor,the gas concentration calculation and its temperature compensation algorithms were expounded.Next,taking CO and CH_(4) as examples,the liner correlation coefficients of absorbance and the temperature correction factors of the two indicator gases were calculated,and then the errors of concentration measurement for CO,CO_(2),CH_(4) and C_(2)H_(4) were further analyzed.The results disclose that the designed NDIR sensors can satisfy the requirements of industrial standards for monitoring the indicator gases for coal fire hazards.For the established NDIR-based monitoring system,the NDIRbased spectrum analyzer and its auxiliary equipment boast intrinsically safe and explosion-proof performances and can achieve real-time and in-situ detection of indicator gases when installed close to the coal fire risk area underground.Furthermore,a field application of the NDIR-based monitoring system in a coal mine shows that the NDIR-based spectrum analyzer has a permissible difference from the chromatography in measuring the concentrations of various indicator gases.Besides,the advantages of high accuracy,quick analysis and excellent security of the NDIR-based monitoring system have promoted its application in many coal mines.展开更多
The purpose was to define the control efficiency and safety of 20% cy- halofop-butyl WP on grass weeds in direct seeded rice fields, in order to provide the basis for chemical weeding. This study measured Leptochloa c...The purpose was to define the control efficiency and safety of 20% cy- halofop-butyl WP on grass weeds in direct seeded rice fields, in order to provide the basis for chemical weeding. This study measured Leptochloa chinensis(L.) Nees, Echinoch/oa crusgalli (L.) Beauv and other gramineous weed control efficiency with four concentrations of 20% cyhalofop-dutyl WP and 100 g/L cyhalofop-dutyl EC in direct seeded rice fields, and analyzed the yield-increasing effect and safety of rice. The results showed that 20% cyhalofop-butyl WP had a good control efficiency on grass weeds such as Leptochloa chinensis(L.) Nees, Echinoch/oa crusgalli(L.) Beauv and other grasses. The effective dosage of 90-150 g/hm2 was over 90.7% on Lep- foch/oa chinensis(L.) Nees and the comprehensive control effect of the grass weeds was above 86.7%, which was basically consistent with 100 g/L cyhalofop-dutyl EC. Furthermore, 20% cyhalofop-dutyl WP was high security for direct seeded rice fields. The yield of rice was increased by 10.18%-11.22% after spraying herbicide. There- fore, 20% of cyhalofop-dutyl WP can be used as a special herbicide for controlling Leptochloa chinensis(L.) Beauv in direct seeded rice fields, and has a good applica- tion prospect.展开更多
Aiming at the application of a wireless sensor network to locating miners in underground mine,we design a wireless sensor network location node system,considering the communication performance and the intrinsic safety...Aiming at the application of a wireless sensor network to locating miners in underground mine,we design a wireless sensor network location node system,considering the communication performance and the intrinsic safety. The location node system consists of a mobile node,several fixed nodes,and a sink node,all of whose circuits were designed based on CC2430. A varistor and a RC circuit were used in the reset circuit of a sensor node to guarantee the intrinsic safety by reducing discharge energy,the theoretical analysis of the discharge energy shows that the reset circuit is an intrinsic safety one. The analysis and simulation about the performance of the location node system are discussed,such as network communication delay and packet loss rate,the results show that the highest network communication delay of the system is about 0.11 seconds,and the highest packet loss rate is about 0.13,which assures the location node system has a high reliability,and can locate miners in the underground mine.展开更多
Aiming to make a high power direct current supply safely used in coal mine production, this paper made a deep research on characteristics of intrinsically safe power supply, using the mathematical model established ac...Aiming to make a high power direct current supply safely used in coal mine production, this paper made a deep research on characteristics of intrinsically safe power supply, using the mathematical model established according to coal mine intrinsic safety standards. It provides theory support for the application of high power intrinsically safe power supply. The released energy of output short circuit of switch power supply, and the close related factors that influence the biggest output short-circuit spark discharge energy are the theoretical basis of the power supply. It is shown how to make a high power intrinsically safe power supply using the calculated values in the mathematical model, and take values from intrinsically safe requirements parameters scope, then this theoretical calculation value can be developed as the ultimate basis for research of the power supply. It gets the identification method of intrinsically safe from mathematics model of intrinsically safe power supply characteristics study, which solves the problem of theory and application of designing different power intrinsically safe power supply, and designs a kind of high power intrinsically safe power supply through this method. energy, flyback展开更多
Multi-factor productivity(MFP) in underground coal mining has been on the decline for the last decade.The mining industry requires a viable and sustainable approach to overcome the current downtrend. This is only poss...Multi-factor productivity(MFP) in underground coal mining has been on the decline for the last decade.The mining industry requires a viable and sustainable approach to overcome the current downtrend. This is only possible by concurrently focussing on productivity improvement and operating costs reduction,delivered through both incremental and step change technology development. Four technologies are presented in this paper: fibre optic borehole sensing has been demonstrated to reveal detailed information about gas flow influx, water level and borehole blockage events occurring along the length of a surfaceto-inseam lateral. Fibre optic gas sensing has also been investigated, and this technology promises a remote, intrinsically safe, distributed solution. Recent developments in continuous water jet drilling technology have demonstrated a step change increase in drilling rates and flexibility for coal seam degassing,applicable in both surface-to-inseam and underground in-seam applications. The application of water jet technology to the cable bolt drilling problem offers potential to address a serious health and safety and productivity issue in the roadway development process.展开更多
Described the development of an Intrinsically Safe System for continuous monitoring of load and convergence of powered roof supports installed at Iongwall faces. The system developed for monitoring of behavior of a po...Described the development of an Intrinsically Safe System for continuous monitoring of load and convergence of powered roof supports installed at Iongwall faces. The system developed for monitoring of behavior of a powered support in a mechanized Iongwall sublevel caving face. The logging system can be programmed for logging the data from the sensors at different logging intervals ranging from 16 h to 1 ms for logging variation in hydraulic pressures in legs and convergence of the support during progressive face advance. For recording dynamic loads, the data logger can be programmed to start fast logging, say at 10 ms intervals, when the pressure in a leg reaches a pre-specified threshold value, and continue fast logging until the pressure drops below this threshold value. This fast logging automatically stops when the pressure drops below this threshold value.展开更多
Security issues are always difficult to deal with in mobile ad hoe networks. People seldom studied the costs of those security schemes respectively and for some security methods designed and adopted beforehand, their ...Security issues are always difficult to deal with in mobile ad hoe networks. People seldom studied the costs of those security schemes respectively and for some security methods designed and adopted beforehand, their effects are often investigated one by one. In fact, when facing certain attacks, different methods would respond individually and result in waste of resources. Making use of the cost management idea, we analyze the costs of security measures in mobile ad hoc networks and introduce a security framework based on security mechanisms cost management. Under the framework, the network system's own tasks can be finished in time and the whole network's security costs can be decreased. We discuss the process of security costs computation at each mobile node and in certain nodes groups. To show how to use the proposed security framework in certain applications, we give examples of DoS attacks and costs computation of defense methods. The results showed that more secure environment can be achieved based on the security framework in mobile ad hoc networks.展开更多
This paper tries to comprehensively summarize the reasons of damages at the Great East Japan Earthquake on March 11, 2011 and what are the lessons in terms of earthquake and tsunami safety of building and cities. The ...This paper tries to comprehensively summarize the reasons of damages at the Great East Japan Earthquake on March 11, 2011 and what are the lessons in terms of earthquake and tsunami safety of building and cities. The paper examines the damage of tsunami affected areas and analyses the damage to extract lessons in order to safely reconstruct the affected areas from the view point of building regulations such as "Disaster Risk Area" provided by the Article 39 of the Building Standard Law and the Urbanization Control Area and UPA (Urbanization Promotion Area) provided by the Article 8 of the Ordinance of the City Planning Law of Japan.展开更多
In the paper we propose a general, abstract framework for Automatic Secret Generation and Sharing (ASGS) that should be independent of underlying Secret Sharing Scheme (SSS). ASGS allows to prevent the Dealer from kno...In the paper we propose a general, abstract framework for Automatic Secret Generation and Sharing (ASGS) that should be independent of underlying Secret Sharing Scheme (SSS). ASGS allows to prevent the Dealer from knowing the secret. The Basic Property Conjecture (BPC) forms the base of the framework. Due to the level of abstraction, results are portable into the realm of quantum computing. Two situations are discussed. First concerns simultaneous generation and sharing of the random, prior nonexistent secret. Such a secret remains unknown until it is reconstructed. Next, we propose the framework for automatic sharing of a known secret. In this case the Dealer does not know the secret and the secret Owner does not know the shares. We present opportunities for joining ASGS with other extended capabilities, with special emphasis on PVSS and pre-positioned secret sharing. Finally, we illustrate framework with practical implementation.展开更多
文摘AIM: To investigate the effi cacy and safety of rabepra-zole under continuous non-steroidal anti-inflammatory drug (NSAID) administration for NSAID-induced ulcer in Japan. METHODS: Subjects comprised patients undergoing NSAID treatment in whom upper gastrointestinal en-doscopy revealed an ulcerous lesion (open ulcer) with diameter ≥ 3 mm, who required continuous NSAID treatment. Endoscopies were performed at the start of treatment, during the treatment period, and at the conclusion (or discontinuation) of treatment. Findings were evaluated as size (maximum diameter) and stage based on the Sakita-Miwa classifi cation. An ulcer was regarded as cured when the "white coating" was seen to have disappeared under endoscopy. As criteria for evaluating safety, all medically untoward symptoms and signs (adverse events, laboratory abnormalities, accidental symptoms, etc.) occurring after the start of rabeprazole treatment were handled as adverse events.RESULTS: Endoscopic cure rate in 38 patients in the efficacy analysis (endoscopic evaluation) was 71.1% (27/38). Among those 38 patients, 35 had gastric ulcer with a cure rate of 71.4% (25/35), and 3 had duodenal ulcer with a cure rate of 66.7% (2/3). Three adverse drug reactions were reported from 64 patients in the safety analysis (interstitial pneumonia, low white blood cell count and pruritus); thus, the incidence rate for adverse drug reactions was 4.7% (3/64).CONCLUSION: The treatment efficacy of rabeprazole for NSAID-induced ulcer under continuous NSAID ad-ministration was confi rmed.
基金The National Natural Science Foundation of China(No.71371050)
文摘Two complementary firms' information sharing and security investment are investigated. When two complementary firms with heterogeneous assets are both breached, it is assumed that they suffer different losses which are associated with their information assets. Some insights about optimal strategies for the firms and the attacker are obtained by the game theory, which forms a comparison with those derived from substitutable firms, and those derived from complementary firms with homogenous loss. In addition, both the unit transform cost of investment and the extent of firms'loss affect the optimal strategies.Assuming that firms can control information sharing, security investments and both of them, respectively, the effect of the social planner is further analyzed on the information sharing, firms' aggregate defence, the aggregate attack and social total cost. Finally, some policy advice is provided through numerical simulation. Results show that firms are willing to choose security investment centrally rather than individually, but an intervention in information sharing by the social planner may not necessarily be preferable.
基金Project(2021MD703848) supported by the China Postdoctoral Science FoundationProjects(52174229, 52174230)supported by the National Natural Science Foundation of China+1 种基金Project(2021-KF-23-04) supported by the Natural Science Foundation of Liaoning Province,ChinaProject(2020CXNL10) supported by the Fundamental Research Funds for the Central Universities,China。
文摘Coal mine fires,which can cause heavy casualties,environmental damages and a waste of coal resources,have become a worldwide problem.Aiming at overcoming the drawbacks,such as a low analysis efficiency,poor stability and large monitoring error,of the existing underground coal fire monitoring technology,a novel monitoring system based on non-dispersive infrared(NDIR)spectroscopy is developed.In this study,first,the measurement principle of NDIR sensor,the gas concentration calculation and its temperature compensation algorithms were expounded.Next,taking CO and CH_(4) as examples,the liner correlation coefficients of absorbance and the temperature correction factors of the two indicator gases were calculated,and then the errors of concentration measurement for CO,CO_(2),CH_(4) and C_(2)H_(4) were further analyzed.The results disclose that the designed NDIR sensors can satisfy the requirements of industrial standards for monitoring the indicator gases for coal fire hazards.For the established NDIR-based monitoring system,the NDIRbased spectrum analyzer and its auxiliary equipment boast intrinsically safe and explosion-proof performances and can achieve real-time and in-situ detection of indicator gases when installed close to the coal fire risk area underground.Furthermore,a field application of the NDIR-based monitoring system in a coal mine shows that the NDIR-based spectrum analyzer has a permissible difference from the chromatography in measuring the concentrations of various indicator gases.Besides,the advantages of high accuracy,quick analysis and excellent security of the NDIR-based monitoring system have promoted its application in many coal mines.
基金Supported by Natural Science Foundation of Hunan Province(12JJ6026)Innovation Platform in Higher Educational Institutions of Hunan Province(14K053)Hunan Province Higher Educational Institutions Industrialization Program(13CY030)~~
文摘The purpose was to define the control efficiency and safety of 20% cy- halofop-butyl WP on grass weeds in direct seeded rice fields, in order to provide the basis for chemical weeding. This study measured Leptochloa chinensis(L.) Nees, Echinoch/oa crusgalli (L.) Beauv and other gramineous weed control efficiency with four concentrations of 20% cyhalofop-dutyl WP and 100 g/L cyhalofop-dutyl EC in direct seeded rice fields, and analyzed the yield-increasing effect and safety of rice. The results showed that 20% cyhalofop-butyl WP had a good control efficiency on grass weeds such as Leptochloa chinensis(L.) Nees, Echinoch/oa crusgalli(L.) Beauv and other grasses. The effective dosage of 90-150 g/hm2 was over 90.7% on Lep- foch/oa chinensis(L.) Nees and the comprehensive control effect of the grass weeds was above 86.7%, which was basically consistent with 100 g/L cyhalofop-dutyl EC. Furthermore, 20% cyhalofop-dutyl WP was high security for direct seeded rice fields. The yield of rice was increased by 10.18%-11.22% after spraying herbicide. There- fore, 20% of cyhalofop-dutyl WP can be used as a special herbicide for controlling Leptochloa chinensis(L.) Beauv in direct seeded rice fields, and has a good applica- tion prospect.
基金Projects 20070411065 supported by the China Postdoctoral Science Foundation0801028B by the Jiangsu Postdoctoral Science Research Foundation
文摘Aiming at the application of a wireless sensor network to locating miners in underground mine,we design a wireless sensor network location node system,considering the communication performance and the intrinsic safety. The location node system consists of a mobile node,several fixed nodes,and a sink node,all of whose circuits were designed based on CC2430. A varistor and a RC circuit were used in the reset circuit of a sensor node to guarantee the intrinsic safety by reducing discharge energy,the theoretical analysis of the discharge energy shows that the reset circuit is an intrinsic safety one. The analysis and simulation about the performance of the location node system are discussed,such as network communication delay and packet loss rate,the results show that the highest network communication delay of the system is about 0.11 seconds,and the highest packet loss rate is about 0.13,which assures the location node system has a high reliability,and can locate miners in the underground mine.
文摘Aiming to make a high power direct current supply safely used in coal mine production, this paper made a deep research on characteristics of intrinsically safe power supply, using the mathematical model established according to coal mine intrinsic safety standards. It provides theory support for the application of high power intrinsically safe power supply. The released energy of output short circuit of switch power supply, and the close related factors that influence the biggest output short-circuit spark discharge energy are the theoretical basis of the power supply. It is shown how to make a high power intrinsically safe power supply using the calculated values in the mathematical model, and take values from intrinsically safe requirements parameters scope, then this theoretical calculation value can be developed as the ultimate basis for research of the power supply. It gets the identification method of intrinsically safe from mathematics model of intrinsically safe power supply characteristics study, which solves the problem of theory and application of designing different power intrinsically safe power supply, and designs a kind of high power intrinsically safe power supply through this method. energy, flyback
基金Australian Coal Association Research Program (ACARP)CRCMining’s Coal Technologies and Fugitive Emissions Research programThe University of Queensland
文摘Multi-factor productivity(MFP) in underground coal mining has been on the decline for the last decade.The mining industry requires a viable and sustainable approach to overcome the current downtrend. This is only possible by concurrently focussing on productivity improvement and operating costs reduction,delivered through both incremental and step change technology development. Four technologies are presented in this paper: fibre optic borehole sensing has been demonstrated to reveal detailed information about gas flow influx, water level and borehole blockage events occurring along the length of a surfaceto-inseam lateral. Fibre optic gas sensing has also been investigated, and this technology promises a remote, intrinsically safe, distributed solution. Recent developments in continuous water jet drilling technology have demonstrated a step change increase in drilling rates and flexibility for coal seam degassing,applicable in both surface-to-inseam and underground in-seam applications. The application of water jet technology to the cable bolt drilling problem offers potential to address a serious health and safety and productivity issue in the roadway development process.
文摘Described the development of an Intrinsically Safe System for continuous monitoring of load and convergence of powered roof supports installed at Iongwall faces. The system developed for monitoring of behavior of a powered support in a mechanized Iongwall sublevel caving face. The logging system can be programmed for logging the data from the sensors at different logging intervals ranging from 16 h to 1 ms for logging variation in hydraulic pressures in legs and convergence of the support during progressive face advance. For recording dynamic loads, the data logger can be programmed to start fast logging, say at 10 ms intervals, when the pressure in a leg reaches a pre-specified threshold value, and continue fast logging until the pressure drops below this threshold value. This fast logging automatically stops when the pressure drops below this threshold value.
文摘Security issues are always difficult to deal with in mobile ad hoe networks. People seldom studied the costs of those security schemes respectively and for some security methods designed and adopted beforehand, their effects are often investigated one by one. In fact, when facing certain attacks, different methods would respond individually and result in waste of resources. Making use of the cost management idea, we analyze the costs of security measures in mobile ad hoc networks and introduce a security framework based on security mechanisms cost management. Under the framework, the network system's own tasks can be finished in time and the whole network's security costs can be decreased. We discuss the process of security costs computation at each mobile node and in certain nodes groups. To show how to use the proposed security framework in certain applications, we give examples of DoS attacks and costs computation of defense methods. The results showed that more secure environment can be achieved based on the security framework in mobile ad hoc networks.
文摘This paper tries to comprehensively summarize the reasons of damages at the Great East Japan Earthquake on March 11, 2011 and what are the lessons in terms of earthquake and tsunami safety of building and cities. The paper examines the damage of tsunami affected areas and analyses the damage to extract lessons in order to safely reconstruct the affected areas from the view point of building regulations such as "Disaster Risk Area" provided by the Article 39 of the Building Standard Law and the Urbanization Control Area and UPA (Urbanization Promotion Area) provided by the Article 8 of the Ordinance of the City Planning Law of Japan.
文摘In the paper we propose a general, abstract framework for Automatic Secret Generation and Sharing (ASGS) that should be independent of underlying Secret Sharing Scheme (SSS). ASGS allows to prevent the Dealer from knowing the secret. The Basic Property Conjecture (BPC) forms the base of the framework. Due to the level of abstraction, results are portable into the realm of quantum computing. Two situations are discussed. First concerns simultaneous generation and sharing of the random, prior nonexistent secret. Such a secret remains unknown until it is reconstructed. Next, we propose the framework for automatic sharing of a known secret. In this case the Dealer does not know the secret and the secret Owner does not know the shares. We present opportunities for joining ASGS with other extended capabilities, with special emphasis on PVSS and pre-positioned secret sharing. Finally, we illustrate framework with practical implementation.