We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attrac...We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attractor, this condition depends on pulse vaccination proportion p. We also obtain the condition of the global asymptotic stability of the solution. The condition shows that large enough pulse vaccination proportion and relatively small interpulse time lead to the eradication of the diseases. Moreover the results of the theoretical study might be instructive to the epidemiology of HIV.展开更多
基金The research is supported by the National Science Foundation of Henan Province(No. 0611051800).
文摘We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attractor, this condition depends on pulse vaccination proportion p. We also obtain the condition of the global asymptotic stability of the solution. The condition shows that large enough pulse vaccination proportion and relatively small interpulse time lead to the eradication of the diseases. Moreover the results of the theoretical study might be instructive to the epidemiology of HIV.
