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小型猪经脉不通病理模型的宏观定量观察法 被引量:5
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作者 李宏彦 王燕平 +7 位作者 张维波 佘锐萍 吴桥兴 贾术永 田宇瑛 王广军 王泽 庞莉 《中国中医基础医学杂志》 CAS CSCD 北大核心 2016年第4期525-528,共4页
目的:建立小型猪经脉不通病理模型的宏观定量观察法,为中医理论的实验研究提供新途径。方法:使用凝胶注射法堵塞小型猪的胃经和肾经低流阻通道,制造经脉不通病理模型,测量造模前后小型猪24 h的饮水量、粪便湿重、干重和尿量,测量造模前... 目的:建立小型猪经脉不通病理模型的宏观定量观察法,为中医理论的实验研究提供新途径。方法:使用凝胶注射法堵塞小型猪的胃经和肾经低流阻通道,制造经脉不通病理模型,测量造模前后小型猪24 h的饮水量、粪便湿重、干重和尿量,测量造模前后第52天的体质量和体尺以及造模后第52天的牙齿尺寸与个数,测量各脏器的最大面积和质量。在上述数据基础上,计算粪便含水量、脏器系数、脏器面积系数和肠长度系数。结果:获得上述指标的定量数据,初步建立了小型猪的宏观定量观察法。结论:使用该方法观察小型猪经脉不通病理模型具有可行性。 展开更多
关键词 宏观定量法 小型猪 经脉不通 病理模型 经络
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Quantitative determination of PFC3D microscopic parameters 被引量:5
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作者 LI Zhuo RAO Qiu-hua 《Journal of Central South University》 SCIE EI CAS CSCD 2021年第3期911-925,共15页
It is important to calibrate micro-parameters for applying partied flow code(PFC)to study mechanical characteristics and failure mechanism of rock materials.Uniform design method is firstly adopted to determine the mi... It is important to calibrate micro-parameters for applying partied flow code(PFC)to study mechanical characteristics and failure mechanism of rock materials.Uniform design method is firstly adopted to determine the microscopic parameters of parallel-bonded particle model for three-dimensional discrete element particle flow code(PFC3D).Variation ranges of microscopic of the microscopic parameters are created by analyzing the effects of microscopic parameters on macroscopic parameters(elastic modulus E,Poisson ratio v,uniaxial compressive strengthσc,and ratio of crack initial stress to uniaxial compressive strengthσci/σc)in order to obtain the actual uniform design talbe.The calculation equations of the microscopic and macroscopic parameters of rock materials can be established by the actual uniform design table and the regression analysis and thus the PFC3D microscopic parameters can be quantitatively determined.The PFC3D simulated results of the intact and pre-cracked rock specimens under uniaxial and triaxial compressions(including the macroscopic mechanical parameters,stress−strain curves and failure process)are in good agreement with experimental results,which can prove the validity of the calculation equations of microscopic and macroscopic parameters. 展开更多
关键词 quantitative relationship of microscopic and macroscopic parameters uniform design method three-dimensional particle flow code(PFC3D) ROCK
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