天然方解石的定代和顺磁共振研究

用ESR分析了天然方解石(CaCO_3)中的杂质Mn^(2+)离子和天然顺磁缺陷的性质。有关谱的理论计算基本和实验结果一致.解释了热处理和辐照样品出现的一些实验现象,最后提出了如何克服干扰解决含有一些杂质Mn^(2+)离子样品的定代问题。

Enhancing Na^(+) diffusion dynamics and structural stability of O3-NaMn_(0.5)Ni_(0.5)O_(2)cathode by Sc and Zn dual-substitution

Sc and Zn were introduced into O3-NaMn_(0.5)Ni_(0.5)O_(2)(NaMN)using the combination of solution combustion and solid-state method.The effect of Sc and Zn dual-substitution on Na^(+) diffusion dynamics and structural stability of NaMN was investigated.The physicochemical characterizations suggest that the introduction of Sc and Zn broaden Na^(+) diffusion channels and weaken the Na—O bonds,thereby facilitating the diffusion of sodium ions.Simulations indicate that the Sc and Zn dual-substitution decreases the diffusion barrier of Na-ions and improves the conductivity of the material.The dual-substituted NaMn_(0.5)Ni_(0.4)Sc_(0.04)Zn_(0.04)O_(2)(Na MNSZ44)cathode delivers impressive cycle stability with capacity retention of 71.2%after 200 cycles at 1C and 54.8%after 400 cycles at 5C.Additionally,the full cell paired with hard carbon anode exhibits a remarkable long-term cycling stability,showing capacity retention of 64.1%after 250 cycles at 1C.These results demonstrate that Sc and Zn dual-substitution is an effective strategy to improve the Na^(+) diffusion dynamics and structural stability of NaMN.

ROBUST OPTIMIZATION OF AERODYNAMIC DESIGN USING SURROGATE MODEL

To reduce the high computational cost of the uncertainty analysis, a procedure is proposed for the aerodynamic optimization under uncertainties, in which the surrogate model is used to simplify the computation of the uncertainty analysis. The surrogate model is constructed by using the Latin Hypercube design and the Kriging model. The random parameters are used to account for the small manufacturing errors and the variations of operating conditions. Based on the surrogate model, an uncertainty analysis approach, called the Monte Carlo simulation, is used to compute the mean value and the variance of the predicated performance. The robust optimization for aerodynamic design is formulated, and solved by the genetic algorithm. And then, an airfoil optimization problem is used to test the proposed procedure. Results show that the optimal solutions obtained from the uncertainty-based optimization formulation are less sensitive to uncertainties. And the design constraints are still satisfied under the uncertainties.

Oriented quantum coalgebra structure on the tensor product of an oriented quantum coalgebra with itself

Oriented quantum algebras （coalgebras） are generalizations of quasitriangular Hopf algebras （coquasitriangular Hopf algebras） and account for regular isotopy invariants of oriented 1-1 tangles, oriented knots and links. Let （H, or, D, U） be an oriented quantum coalgebra over the field k. Then （H×H, φ, D×D, U× U） is a trivial oriented quantum coalgebra structure on the tensor product of coalgebra H with itself, where φ （a × b, c × d） = σ-（ a, c）σ （b, d）. This paper presents the oriented quantum coalgebra structure （ H×H, σ, D×D, U× U） on coalgebra H× H, where σ（ a × b, c× d） = σ ^-1 （ d1, a1 ） σ（ a2, c1 ） σ^-1 （ d2, b1 ） σ（ b2, c2 ）. So a nontrivial oriented quantum coalgebra structure is obtained and it is dual to Radford＇s results in the paper ＂On the tensor product of an oriented quantum algebra with itself＂ published in 2007. Theoretically, the results of this paper are important in constructing the invariants of oriented knots and links.

Sensitive liquid chromatography electrospray ionization ion-trap mass spectrometry for the determination of rupatadine in human plasma

Aim To develop and validate a sensitive and specific liquid chromatography electrospray ionization ion-trap mass spectrometry （LC-ESI-MS/MS） method for the identification and concentration of rupatadine in human plasma. Methods After the addition of the internal standard （IS, loratadine） and 0.01 mol·L^-1 sodium hydroxide solution, plasma samples were extracted with methylene chloride： ethyl acetate mixture （20：80, V/V）. The organic layer was evaporated under vacuum drying at 37 ℃. The residue was reconstituted with 200 μL mobile phase. Chromatography was performed on an Agilent Eclipse XDB-C18 （4.6 mm × 150 mm, 5 μm） column with a mobile phase consisting of acetonitrile （1% formic acid） -20 mmol·L^-1 ammonium acetate （76：24, V/V） at a flow-rate of 0.6 mL·min^-1. Detection was performed on Agilent MSD Trap XCT ion-trap mass spectrometry connected to a Agilent 1100 high performance liquid chromatography （HPLC） by selected reaction monitoring （SRM） mode via electrospray ionization （ESI） source. Rupatadine （MRM m/z 416 → 309） and loratadine （MRM m/z 383 → 337） were detected by Agilent MSD Trap XCT ion-trap mass analyser. Results The method was proved to be sensitive and specific by testing 20 different plasma batches. Linearity was established for the range of concentrations 0.05 - 14.0 ng·mL^ -1 with a coefficient of determination （r） of 0.998. The intra-and inter-day precision （RSD %） were lower than 15% and accuracy ranged from 85.1% to 114.0%. The lower limit of quantitation （LLOQ） was identifiable and reproducible at 0.05 ng·mL^-1 with a precision of 9.22% （n =5）. Conclusion The proposed method is sensitive and reproducible enough to be used in pharmacokinetic, bioavailability or bioequivalence studies of rupatadine.

SYMMETRIC POSITIVE DEFINITE SOLUTIONS OF MATRIX EQUATIONS (AX,XB)=(C,D) AND AXB=C

The symmetric positive definite solutions of matrix equations (AX,XB)=(C,D) and AXB=C are considered in this paper. Necessary and sufficient conditions for the matrix equations to have symmetric positive definite solutions are derived using the singular value and the generalized singular value decompositions. The expressions for the general symmetric positive definite solutions are given when certain conditions hold.

Note on a diffusive ratio-dependent predator-prey model

Subject to the homogeneous Neumann boundary condition, a ratio-dependent predator-prey reaction diffusion model is discussed. An improved result for the model is derived, that is, the unique positive constant steady state is the global stability. This is done using the comparison principle and establishing iteration schemes involving positive solutions supremum and infimum. The result indicates that the two species will ultimately distribute homogeneously in space. In fact, the comparison argument and iteration technique to be used in this paper can be applied to some other models. This method deals with the not-existence of a non-constant positive steady state for some reaction diffusion systems, which is rather simple but sufficiently effective.

Effects of in vitro subculture on the physiological characteristics of adventitious root formation in microshoots of Castanea mollissima cv.'yanshanhong'

Microshoots of Castanea mollissima cv.＇yanshanhong＇ in vitro acquired an enhanced rooting capability with increasing numbers of subculture.In this study,we investigated the effect of successive subculture on adventitious root formation in vitro by the determination of the endogenous hormone level and the enzyme activity.The levels of indoleacetic acid（IAA）,abscisic acid（ABA）,cytokinins（CTK） and gibberellic acid（GA3） were determined by high performance liquid chromatography（HPLC）,and the activities of indoleacetic acid oxidase（IAAO）,peroxidase oxidase（POD）,and polyphenol oxidase（PPO） were measured by ultraviolet-spectrophotometer assay after the induction of rooting at 2nd,4th,6th and 8th subculture.The relationships between physiological characteristics and subculture numbers or rooting rate were as follows：The levels of endogenous IAA in microshoots gradually increased,and endogenous levels of ABA,CTK and GA3 in microshoots decreased slightly after serial subcultures.The level of IAA was highly correlated with subculture numbers and rooting rates.The ratios of IAA/ABA and IAA/CTK both acutely raised with increasing rooting rate during successive subcultures and had high correlations with rooting rate.The activity of IAAO and POD are significantly negatively related with subculture numbers,and the activity of PPO increased after subcultures.

Prediction of Subcellular Localization of Eukaryotic Proteins Using Position-Specific Profiles and Neural Network with Weighted Inputs

Subcellular location is one of the key biological characteristics of proteins. Position-specific profiles （PSP） have been introduced as important characteristics of proteins in this article. In this study, to obtain position-specific profiles, the Position Specific lterative-Basic Local Alignment Search Tool （PSI-BLAST） has been used to search for protein sequences in a database. Position-specific scoring matrices are extracted from the profiles as one class of characteristics. Four-part amino acid compositions and lst-7th order dipeptide compositions have also been calculated as the other two classes of characteristics. Therefore, twelve characteristic vectors are extracted from each of the protein sequences. Next, the characteristic vectors are weighed by a simple weighing function and inputted into a BP neural network predictor named PSP-Weighted Neural Network （PSP-WNN）. The Levenberg-Marquardt algorithm is employed to adjust the weight matrices and thresholds during the network training instead of the error back propagation algorithm. With a jackknife test on the RH2427 dataset, PSP-WNN has achieved a higher overall prediction accuracy of 88.4% rather than the prediction results by the general BP neural network, Markov model, and fuzzy k-nearest neighbors algorithm on this dataset. In addition, the prediction performance of PSP-WNN has been evaluated with a five-fold cross validation test on the PK7579 dataset and the prediction results have been consistently better than those of the previous method on the basis of several support vector machines, using compositions of both amino acids and amino acid pairs. These results indicate that PSP-WNN is a powerful tool for subcellular localization prediction. At the end of the article, influences on prediction accuracy using different weighting proportions among three characteristic vector categories have been discussed. An appropriate proportion is considered by increasing the prediction accuracy.

Rainfall and inflow effects on soil erosion for hillslopes dominated by sheet erosion or rill erosion in the Chinese Mollisol region

Erosion agents and patterns profoundly affect hillslope soil loss characteristics. However, few attempts have been made to analyze the effects of rainfall and inflow on soil erosion for hillslopes dominated by sheet erosion or rill erosion in the Chinese Mollisol region. The objective of this study was to discuss the erosive agent(rainfall or inflow), hillslope erosion pattern(sheet erosion or rill erosion) and slope gradient effects on runoff and soil losses. Two soil pans(2.0 m long, 0.5 m wide and 0.5 m deep) with 5° and 10° slopes were subjected to rainfall(0 and 70 mm h–1) and inflow(0 and 70 mm h–1) experiments. Three experimental combinations of rainfall intensity(RI) and inflow rate(IR) were tested using the same water supply of 70 mm by controllingthe run time. A flat soil surface and a soil bed with a straight initial rill were prepared manually, and represented hillslopes dominated by sheet erosion and rill erosion, respectively. The results showed that soil losses had greater differences among treatments than total runoff. Soil losses decreased in the order of RI70+IR70 > RI70+IR0 > RI0+IR70. Additionally, soil losses for hillslopes dominated by rill erosion were 1.7-2.2 times greater at 5° and 2.5-6.9 times greater at 10° than those for hillslopes dominated by sheet erosion. The loss of <0.25 mm soil particles and aggregates varying from 47.72%-99.60% of the total soil loss played a dominant role in the sediment. Compared with sheet erosion hillslopes, rill erosion hillslopes selectively transported more microaggregates under a relatively stable rill development stage, but rills transported increasinglymore macroaggregates under an active rill development stage. In conclusion, eliminating raindrop impact on relatively gentle hillslopes and preventing rill development on relatively steep hillslopes would be useful measures to decrease soil erosion and soil degradation in the Mollisol region of northeastern China.

The Algebraic Criteria for the All-delay Stabilityof Two-dim ensional Degenerate Differential System swith Delay

This paper give the algebraic criteria for all delay stability of two dimensional degenerate differential systems with delays and give two examples to illustrate the use of them.

Multi-scale seismic full waveform inversion in the frequency-domain with a multi-grid method

Although full waveform inversion in the frequency domain can overcome the local minima problem in the time direction, such problem still exists in the space direction because of the media subsurface complexity. Based on the optimal steep descent methods, we present an algorithm which combines the preconditioned bi-conjugated gradient stable method and the multi-grid method to compute the wave propagation and the gradient space. The multiple scale prosperity of the waveform inversion and the multi-grid method can overcome the inverse problems local minima defect and accelerate convergence. The local inhomogeneous three-hole model simulated results and the Marmousi model certify the algorithm effectiveness.

Duality theorem for smash coproduct over quantum groupoids

The duality theorem of generalized weak smash coproducts of weak module coalgebras and comodule coalgebras over quantum groupoids is studied.Let H be a weak Hopf algebra,C a left weak H-comodule coalgebra and D a left weak H-module coalgebra.First,a weak generalized smash coproduct C×lH D over quantum groupoids is defined and the module and comodule structures on it are constructed.The weak generalized right smash coproduct C×rL D is similar.Then some isomorph-isms between them are obtained.Secondly,by introducing some concepts of a weak convolution invertible element,a weak co-inner coaction and a strongly relative co-inner coaction,a sufficient condition for C×rH D to be isomorphic to Cv D is obtained,where v∈WC（C,H）and the coaction of H on D is right strongly relative co-inner.Finally,the duality theorem for a generalized smash coproduct over quantum groupoids,（C×lH H）×lH H≌Cv（H×lH H）,is obtained.

ALPHA THERMOLUMINESCENCE DOSIMETRY IN DATING OF POTTERY

This article describes the measurement of internal alpha dose-rate in pottery using ultrathin CaSO4: Tin thermoluminescence dosimeter. Among the advantages ofthe techllique are not only convenience, accuracy, lowcost, but also the beta dose--ratefrom pottery can be obtained at the same time.

A Master-Slave Blockchain Paradigm and Application in Digital Rights Management

Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for pervasive computing that suitable for general PC, mobile device such as smart phones or PADs to participants in the working of mining and verification, in which we separated traditional blockchain model in 2 layer defined as master node layer and a series of slavery agents layer, then we proposed 2 approaches for partially computing model(PCM) and non-computing of model(NCM) in the MSB blockchain, Finally large amounts of simulations manifest the proposed master-slave blockchain scheme is feasible, extendible and suitable for pervasive computing especially in the 5 G generation environment, and can apply in the DRM-related applications.

Analysis of Data on Xanthan Fermentation in Stationary Phase Using Black Box and Metabolic Network Models

The xanthan fermentation data in the stationary phase was analyzed using the black box and the metabolic network models. The data consistency is checked through the elemental balance in the black box model. In the metabolic network model, the metabolic flux distribution in the cell is calculated using the metabolic flux analysis method, then the maintenance coefficients is calculated.

Using the surface panel method to predict the steady performance of ducted propellers

A new numerical method was developed for predicting the steady hydrodynamic performance of ducted propellers. A potential based surface panel method was applied both to the duct and the propeller, and the interaction between them was solved by an induced velocity potential iterative method. Compared with the induced velocity iterative method, the method presented can save programming and calculating time. Numerical results for a JD simplified ducted propeller series showed that the method presented is effective for predicting the steady hydrodynamic performance of ducted propellers.

Location and Analysis of Introgressed Segments in the Parthenogenetic Progenies of Zea mays×Z. diploperennis by GISH

用来自玉米 (ZeamaysL .)与二倍体多年生类玉米 (Z .diploperennisIltis,DoebleyandGuzm偄ｎ)杂交的孤雌生殖后代同一抗病个体的 4个株系进行了基因组原位杂交 ,用改进的杂交技术获得了近 10 0 %的检出率 ,每一检出片段在同源染色体两成员和每两个姊妹染色单体上均有清晰的信号。

Benefit of everolimus in treatment of an intrahepatic cholangiocarcinoma patient with a PIK3CA mutation

Intrahepatic cholangiocarcinoma(ICC) is a relatively rare form of liver cancer with a poor prognosis. The therapeutic options for patients with advanced ICC are limited and usually ineffective. There is currently no approved targeted therapy for ICC, although accumulating evidence supports inhibition of the PI3K/Akt/m TOR signaling pathway as a promising therapeutic strategy in the treatment of ICC. Here, we report a patient with stage IV ICC harboring a PIK3 CA mutation who responded well to the m TOR inhibitor everolimus. Computed tomography and magnetic resonance imaging demonstrated shrinkage of the tumor and maintenance of a partial response for 6.5 mo after everolimus treatment as the best response. To the best of our knowledge, this is the first clinical case report in the literature of clinical benefit from everolimus treatment in an ICC patient with PIK3 CA mutation.

Fission Track Dating of Authigenic Quartz in Red Weathering Crusts of Carbonate Rocks in Guizhou Province

The Cenozoic evolution history of Guizhou Province, which is located on the southeastern flank of the Qinghai-Tibet Plateau, is unclear because of the lack of sedimentation records. The red weathering crusts widespread on the Yunnan-Guizhou Plateau may bear critical information about their evolution history. This work firstly determined the ages of four red weathering crusts in eastern, central and northern Guizhou. The material used in fission track dating is well-crystallized quartz occurring in many in-situ weathering crusts of carbonate rocks. The results showed that the fission track ages of quartz vary over a wide range from 1 to 25 Ma in the four profiles, significantly younger than the ages of the Triassic and Cambrian parent rocks. In combination with the evolution history of the regional geology during the period from 25 to 1 Ma, the ages of quartz can exclude the possibility that the origin of quartz has nothing to do with primary clastic minerals in parent rocks, authigenesis during diagenesis and hydrothermal precipitation or roplacement by volcanic activities. It is deduced that the well-crystallized quartz was precipitated from Si-rich weathering fluids during the weathering process of carbonate rocks. The recorded ages of quartz from the four profiles are consistent with the episodes of the planation surfaces on the Qinghai-Tibet Plateau, the forming stages of red soil in the tropics of South China, the tectonically stable periods in Guizhou, and the ages of weathering in other parts of the world during the Cenozoic era. That is to say, the ages of authigenic quartz dated by the fission track method are well feasible and credible.