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定心针法针刺联合定冠汤口服治疗冠心病心绞痛的临床疗效及对血清缺血修饰白蛋白、P选择素水平的影响 被引量:4
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作者 梅希玲 范小会 《中医研究》 2022年第2期42-45,共4页
目的:观察定心针法针刺联合定冠汤口服治疗冠心病心绞痛的临床疗效及对血清缺血修饰白蛋白、P选择素(Ps)水平的影响。方法:选择新蔡县中医院心内科住院的冠心病心绞痛患者90例,采用随机对照法分为两组,每组45例。两组均绝对卧床休息,给... 目的:观察定心针法针刺联合定冠汤口服治疗冠心病心绞痛的临床疗效及对血清缺血修饰白蛋白、P选择素(Ps)水平的影响。方法:选择新蔡县中医院心内科住院的冠心病心绞痛患者90例,采用随机对照法分为两组,每组45例。两组均绝对卧床休息,给予氧气吸入、心电监护等西医常规护理;合并高血压、糖尿病、高脂血症等基础疾病者,规范调控血压、血糖、血脂。对照组给予阿司匹林肠溶片每次100 mg,每日1次,口服;瑞舒伐他汀钙片每次10 mg,每日1次,口服;单硝酸异山梨酯缓释片每次40 mg,每日1次,口服;注射用低分子量肝素钙每次5000 U,每12 h 1次,皮下注射。治疗组在对照组治疗基础上采用定心针法(取穴:内关、膻中、郄门、曲泽、足三里、三阴交),每日1次;同时联合定冠汤(太子参、黄芪、丹参、红花、降香、三七粉、红景天、桂枝、麦冬、黄连、酸枣仁、茯神、炙甘草),每日1剂,每次200 mL,早晚各服1次。两组均以2周为1个疗程,治疗1个疗程后判定疗效。结果:治疗组显效33例,有效10例,无效2例,有效率为95.56%(43/45);对照组显效21例,有效17例,无效7例,有效率为84.44%(38/45)。两组对比,差异有统计学意义(P<0.01)。治疗后,两组中医证候总积分均明显下降,治疗组下降程度明显优于对照组,差异有统计学意义(P<0.05或P<0.01);两组心肌缺血发作次数、持续时间和心肌缺血总负荷均明显降低,且治疗组低于对照组,差异有统计学意义(P<0.01);两组血清缺血修饰白蛋白、Ps水平均明显下降,且治疗组降低幅度大于对照组,差异有统计学意义(P<0.01)。结论:在西医治疗基础上加用定心针法针刺联合定冠汤口服治疗冠心病心绞痛有较好疗效,能改善临床症状和心肌缺血程度,值得临床推广。 展开更多
关键词 冠心病心绞痛 定心针法 定冠汤 中医证候总积分 24 h动态心电图 缺血修饰白蛋白 P选择素 疗效观察
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Needle-embedding therapy combined with basic treatment for stable angina pectoris 被引量:2
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作者 Jie DENG Lanbo FEI +3 位作者 Jianhua ZHOU Song WU Wei HUANG Xia CHEN 《World Journal of Acupuncture-Moxibustion》 CSCD 2018年第2期11-15,80,共6页
Objective: To clarify the clinical efficacy of needle-embedding therapy for stable angina pectoris. Methods: Seventy-six patients with stable angina pectoris were divided into needle-embedding therapy group (group ... Objective: To clarify the clinical efficacy of needle-embedding therapy for stable angina pectoris. Methods: Seventy-six patients with stable angina pectoris were divided into needle-embedding therapy group (group A) and basic treatment group (group B) according to the random number table, with 38 patients in each group. Needle-embedding therapy combined with basic treatment was adopted in group A, and needle-embedding was given once every other day, the needles were retained for 24 h each time and three times of treatment were given each week. basic treatment was applied solely in group B. Four weeks of treatment which means one course were given in two groups, efficacy observation and evaluation were carried out after 1 course of treatment. Results: After treatment, the total effective rate of clinical efficacy was 89.47% in group A and 71.05% in group B (p 〈 0.05), and the total effective rate of electrocardiograph (ECG) efficacy was 84.21% in group A and 63.16% in group B (p〈0.05). After treatment, the score of limitation of motion, score of the sta- ble state of angina pectoris and the score of angina pectoris attack in group A increased by 0.7%, 34,5% and 16.9% respectively when compared with the scores before treatment (t= 1.623, p 〈0.0l; t=3.867, p 〈 0.01 ; t = 1.958, p 〈 0.05), and according to the comparison of the score of satisfaction with treatment and the score of disease perception before and after treatment, the difference was not statistically significant (t=4.972, p 〉 0.05; t=0.999, p 〉 0.05). According to the comparison of the score of limitation of motion, score of angina pectoris attack, score of satisfaction with treatment and the score of disease per- ception in group B before and after treatment, the differences were not statistically significant (t = 1.726, p 〉 0.05; t = 1.594, p 〉 0.05; t = 4.385, p 〉 0.05; t = 0.999, p 〉 0.05). The score of: the stable state of angina pectoris increased by 4.9% (t = 1.780, p 〈 0.05). Conclusion: Needle-embedding in acupoint therapy can effectively improve the clinical efficacy, ECG efficacy and the score of Seattle angina questionnaire (SAQ) of stable angina pectoris. 展开更多
关键词 Needle-embedding therapy Stable angina pectoris Acupuncture-moxibustion therapy
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