It was concluded that the described HPLC method could be used for the assayof salmon calcitonin in injection, as it offers qualified selectivity, accuracy and precision ofanalysis.
An four wheel steering (4WS) feedback control system that simultaneously achieves both body sideslip angle and yaw rate responses always desirable regardless of changes in vehicle dynamics. Quantitative feedback theor...An four wheel steering (4WS) feedback control system that simultaneously achieves both body sideslip angle and yaw rate responses always desirable regardless of changes in vehicle dynamics. Quantitative feedback theory (QFT) is offered as the main tool for designing the control law. Inverted decoupling is also employed to make multivariable quantitative feedback design easier. Various nonlinear analyses are carried out and show that the proposed control system is a robust decoupling controller which not only makes body sideslip angle and yaw rate of the vehicle track the desired reference input signals respectively, but also satisfies the requirement of robustness for the control system. The results also indicate that the control system can make it available to realize ideal lateral steering dynamics tracking for vehicles.展开更多
The present research relies on a cascade control approach through the Monte-Carlo based method in the presence of uncertainties to evaluate the performance of the real overactuated space systems.A number of potential ...The present research relies on a cascade control approach through the Monte-Carlo based method in the presence of uncertainties to evaluate the performance of the real overactuated space systems.A number of potential investigations in this area are first considered to prepare an idea with respect to state-of-the-art.The insight proposed here is organized to present attitude cascade control approach including the low thrust in connection with the high thrust to be implemented,while the aforementioned Monte-Carlo based method is carried out to guarantee the approach performance.It is noted that the investigated outcomes are efficient to handle a class of space systems presented via the center of mass and the moments of inertial.And also a number of profiles for the thrust vector and the misalignments as the disturbances all vary in its span of nominal variations.The acquired results are finally analyzed in line with some well-known benchmarks to verify the approach efficiency.The key core of finding in the research is to propose a novel 3-axis control approach to deal with all the mentioned uncertainties of space systems under control,in a synchronous manner,as long as the appropriate models in the low-high thrusts are realized.展开更多
The aim of this study was to establish a quality-control method for calcineurin subunit B(CNB) biological activity determinations. CNB enhances the p-nitrophenylphosphate(p NPP) dephosphorylating activity of calcineur...The aim of this study was to establish a quality-control method for calcineurin subunit B(CNB) biological activity determinations. CNB enhances the p-nitrophenylphosphate(p NPP) dephosphorylating activity of calcineurin subunit A Δ316 mutant(CNAΔ316). A series of CNB concentrations were fitted to a four-parameter equation to calculate the corresponding p NPP maximum dephosphorylation rates. Values were calculated based on biological activity references using a parallel line method. The method was then validated for accuracy, precision, linearity, linear range, sensitivity, specificity, and robustness. The recovery results were greater than 98%. Intra-plate precision was 6.7%, with inter-plate precision of 10.8%. The coefficient of determination was greater than 0.98. The linear range was 0.05–50 μg m L?1, with sensitivity of 50 μg m L?1. Tested cytokines did not induce CNAΔ316 dephosphorylation of p NPP. The chosen CNAΔ316 concentration range did not affect activity determinations.展开更多
文摘It was concluded that the described HPLC method could be used for the assayof salmon calcitonin in injection, as it offers qualified selectivity, accuracy and precision ofanalysis.
文摘An four wheel steering (4WS) feedback control system that simultaneously achieves both body sideslip angle and yaw rate responses always desirable regardless of changes in vehicle dynamics. Quantitative feedback theory (QFT) is offered as the main tool for designing the control law. Inverted decoupling is also employed to make multivariable quantitative feedback design easier. Various nonlinear analyses are carried out and show that the proposed control system is a robust decoupling controller which not only makes body sideslip angle and yaw rate of the vehicle track the desired reference input signals respectively, but also satisfies the requirement of robustness for the control system. The results also indicate that the control system can make it available to realize ideal lateral steering dynamics tracking for vehicles.
文摘The present research relies on a cascade control approach through the Monte-Carlo based method in the presence of uncertainties to evaluate the performance of the real overactuated space systems.A number of potential investigations in this area are first considered to prepare an idea with respect to state-of-the-art.The insight proposed here is organized to present attitude cascade control approach including the low thrust in connection with the high thrust to be implemented,while the aforementioned Monte-Carlo based method is carried out to guarantee the approach performance.It is noted that the investigated outcomes are efficient to handle a class of space systems presented via the center of mass and the moments of inertial.And also a number of profiles for the thrust vector and the misalignments as the disturbances all vary in its span of nominal variations.The acquired results are finally analyzed in line with some well-known benchmarks to verify the approach efficiency.The key core of finding in the research is to propose a novel 3-axis control approach to deal with all the mentioned uncertainties of space systems under control,in a synchronous manner,as long as the appropriate models in the low-high thrusts are realized.
基金supported by the National Important Novel Medicine Research Project (2012ZX09304010, 2013ZX09102062)the National Natural Science Foundation of China (31270849)
文摘The aim of this study was to establish a quality-control method for calcineurin subunit B(CNB) biological activity determinations. CNB enhances the p-nitrophenylphosphate(p NPP) dephosphorylating activity of calcineurin subunit A Δ316 mutant(CNAΔ316). A series of CNB concentrations were fitted to a four-parameter equation to calculate the corresponding p NPP maximum dephosphorylation rates. Values were calculated based on biological activity references using a parallel line method. The method was then validated for accuracy, precision, linearity, linear range, sensitivity, specificity, and robustness. The recovery results were greater than 98%. Intra-plate precision was 6.7%, with inter-plate precision of 10.8%. The coefficient of determination was greater than 0.98. The linear range was 0.05–50 μg m L?1, with sensitivity of 50 μg m L?1. Tested cytokines did not induce CNAΔ316 dephosphorylation of p NPP. The chosen CNAΔ316 concentration range did not affect activity determinations.
