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甲状腺良性结节单次微波消融治疗的短期疗效评价
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作者 刘俊松 许崇文 +6 位作者 姚小宝 赵瑞敏 汪世洋 赵谦 李宏慧 白艳霞 张少强 《中国耳鼻咽喉头颈外科》 CSCD 2024年第7期414-420,共7页
目的评价甲状腺良性结节单次微波消融治疗的短期效果。方法选择2019年6月~2022年12月在西安交通大学第一附属医院耳鼻咽喉头颈外科诊治的甲状腺良性结节患者,采用微波消融治疗的连续病例,具有完善的随访数据者纳入分析。治疗后1个月复... 目的评价甲状腺良性结节单次微波消融治疗的短期效果。方法选择2019年6月~2022年12月在西安交通大学第一附属医院耳鼻咽喉头颈外科诊治的甲状腺良性结节患者,采用微波消融治疗的连续病例,具有完善的随访数据者纳入分析。治疗后1个月复查甲状腺功能,治疗后3个月、6个月、1年复查超声和甲状腺功能,计算结节体积缩小率(volume reduction rate,VRR)。以1年内末次随访结果为结局变量,纳入性别、年龄、是否合并桥本甲状腺炎、结节纵径、结节实性体积等自变量,进行单因素和多因素分析。结果总计纳入151例患者,共计163个结节,围手术期并发症发生率为1.99%(3/151),治疗后6个月VRR为(79.58±17.70)%,6个月治疗成功率为93.43%(128/137),治疗后1年VRR为(81.24±24.29)%,1年治疗成功率为92.77%(77/83)。单因素及多因素分析显示,结节实性体积和年龄是影响消融后VRR的独立影响因素,年龄的回归系数为0.34,实性体积的回归系数为-0.47,P均<0.05,结节实性体积每增加1 cm3,1年内VRR(%)减少0.47。回归方程:1年内VRR=68.92+0.34×年龄-0.47×实性体积。消融治疗后6个月内血清FT4逐渐下降,促甲状腺激素(TSH)逐渐升高,差异有统计学意义(P<0.05),6个月后FT4逐渐恢复至正常水平,TSH亦逐渐恢复,但至治疗后1年时仍未达到术前水平;治疗后FT3逐渐减低,但各个时间点数值之间差异无统计学意义(P=0.40)。甲状腺结节消融治疗后,甲状腺功能指标平均值出现波动,但均在正常参考范围内。结论甲状腺良性结节微波消融治疗是一种安全有效的治疗方式,其总体治疗成功率可达90%以上。结节实性体积和年龄是影响甲状腺良性结节微波消融效果的独立影响因素。 展开更多
关键词 甲状腺结节 治疗结果 微波消融 实性体积 体积缩小率 结节纵径
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CT影像组学特征联合三维体积因素预测肺腺癌的侵袭性
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作者 郑皓 项萍 +2 位作者 郭艺帆 王军娜 王世威 《浙江临床医学》 2023年第2期172-175,共4页
目的 探讨亚实性结节CT影像组学联合三维体积因素预测浸润性腺癌(IAC)和原位腺癌(AIS)/微浸润性腺癌(MIA)的能力.方法 回顾性分析2017年1月至2020年12月CT表现为亚实性结节且病理证实为肺腺癌患者242例,按照7:3比例随机分为训练集与验证... 目的 探讨亚实性结节CT影像组学联合三维体积因素预测浸润性腺癌(IAC)和原位腺癌(AIS)/微浸润性腺癌(MIA)的能力.方法 回顾性分析2017年1月至2020年12月CT表现为亚实性结节且病理证实为肺腺癌患者242例,按照7:3比例随机分为训练集与验证集,使用3D slicer进行整体结节及实性成分三维体积勾画并提取影像特征,标准化处理后通过F检验筛选最优特征并建立影像组学模型.患者一般资料比较采用t检验、χ^(2)检验或U检验,有统计学意义变量进行多因素分析并联合影像组学建立联合模型,通过受试者工作特征曲线(ROC)评价两种预测模型效能.结果 IAC组的年龄、整体结节体积、实性成分体积、实性成分体积比例均大于AIS/MIA组(P<0.05).多因素分析显示实性体积比例及影像组学分数是预测肺腺癌侵袭性的独立危险因素.影像组学模型和联合诊断两个模型中的AUC在训练队列中分别为0.836、0.854,在验证队列中分别为0.883、0.930,在训练队列和验证队列中,联合诊断模型效能最佳.结论 随着实性成分体积的增加,肺腺癌的侵袭性将增强.基于CT影像组学联合实性成分体积比例对肺腺癌侵袭性的预测具有较高的诊断价值. 展开更多
关键词 结节 肺腺癌 三维体积 成分体积比例 影像组学
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Gas–Liquid Mass Transfer Characteristics in a Gas–Liquid–Solid Bubble Column under Elevated Pressure and Temperature 被引量:3
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作者 靳海波 杨索和 +3 位作者 何广湘 刘德林 佟泽民 朱建华 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2014年第9期955-961,共7页
abstract The volumetric mass transfer coefficient kLa of gases (H2, CO, CO2) and mass transfer coefficient kL on liquid par-affin side were studied using the dynamic absorption method in slurry bubble column reactor... abstract The volumetric mass transfer coefficient kLa of gases (H2, CO, CO2) and mass transfer coefficient kL on liquid par-affin side were studied using the dynamic absorption method in slurry bubble column reactors under elevated temperature and elevated pressure. Meanwhile, gas-holdup and gas-liquid interfacial area a were obtained. The effects of temperature, pressure, superficial gas velocity and solid concentration on the mass transfer coeffi-cient were discussed. Experimental results show that the gas-liquid volumetric mass transfer coefficient kLa and interfacial area a increased with the increase of pressure, temperature, and superficial gas velocity, and decreased with the slurry concentration. The mass transfer coefficient kL increased with increasing superficial gas velocity and temperature and decreased with higher slurry concentration, while it changed slightly with pressure. Ac-cording to analysis of experimental data, an empirical correlation is obtained to calculate the values of kLa for H2 (CO, CO2) in the gas-paraffin-quartz system in a bubble column under elevated temperature and elevated pressure. 展开更多
关键词 Mass transfer characteristicBubble columnElevated pressureElevated temperature
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Practical Performance of High Bulk Modulus Oil
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作者 Toshiyuki Tsubouchi Jitsuo Shinoda 《Journal of Mechanics Engineering and Automation》 2012年第2期119-123,共5页
Although hydraulic drives have an advantage of high power density, volumetric shrinkage of hydraulic fluids due to pressure causes various disadvantages such as delay of hydraulic response and compression energy loss.... Although hydraulic drives have an advantage of high power density, volumetric shrinkage of hydraulic fluids due to pressure causes various disadvantages such as delay of hydraulic response and compression energy loss. Hydraulic fluids of new concept, high bulk modulus oils, have been developed as a new approach to improve the performance of a hydraulic servo system and verified. In this paper, practical performances of high bulk modulus oil, such as oil temperature rise during pump test, air bubbles generation by ultrasonic wave vibration, oxidation stability and anti-wear property, were studied. And the new oil was confirmed to have excellent practical performances besides advantages in pressure response and volumetric efficiency of pumps. Various new applications of the new oil are promising. 展开更多
关键词 Bulk modulus hydraulic fluid volumetric efficiency air bubble anti-wear.
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Improving plasticity of the Zr46Cu46Al8 bulk metallic glass via thermal rejuvenation 被引量:9
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作者 Wenli Song Xiaohe Meng +5 位作者 Yuan Wu Di Cao Hui Wang Xiongjun Liu Xianzhen Wang Zhaoping Lu 《Science Bulletin》 SCIE EI CSCD 2018年第13期840-844,共5页
In this paper, effects of cryogenic thermal cycling on deformation behavior and thermal stability of the Zr46Cu46AI8 bulk metallic glass (BMG) were studied. The results show that with the increase of the number of c... In this paper, effects of cryogenic thermal cycling on deformation behavior and thermal stability of the Zr46Cu46AI8 bulk metallic glass (BMG) were studied. The results show that with the increase of the number of cryogenic thermal cycles (CTC), thermal stability remains almost unchanged, while the plasticity is increased, indicating that the cryogenic thermal cyclic treatment is an effective way to improve plasticity of metallic glasses without distinctly deteriorating thermal stability. Our analysis suggests that the increase in the defect density resulted from the cryogenic thermal treatments are responsible for the plasticity increment. Variation of yield strength can be well interpreted from microstructural percolation which affected by both density and characteristic volume of the defect sites. 展开更多
关键词 Bulk metallic glasses Cryogenic thermal cycling Defect density PLASTICITY
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Unanswered questions in unsaturated soil mechanics 被引量:4
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作者 SHENG DaiChao ZHANG Sheng YU ZhiWu 《Science China(Technological Sciences)》 SCIE EI CAS 2013年第5期1257-1272,共16页
The last two to three decades have seen significant advances in the mechanics of unsaturated soils.It is now widely recognized that the fundamental principles in soil mechanics must cover both saturated and unsaturate... The last two to three decades have seen significant advances in the mechanics of unsaturated soils.It is now widely recognized that the fundamental principles in soil mechanics must cover both saturated and unsaturated soils.Nevertheless,there is still a great deal of uncertainties in the geotechnical community about how soil mechanics principles well-established for saturated soils can be extended to unsaturated soils.There is even wide skepticism about the necessity of such extension in engineering practice.This paper discusses some common pitfalls related to the fundamental principles that govern the volume change,shear strength and hydromechanical behaviour of unsaturated soils.It also attempts to address the issue of engineering relevance of unsaturated soil mechanics. 展开更多
关键词 unsaturated soils constitutive modeling volume change shear strength engineering applications
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