AIM: To discuss the safety, feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation (MWA). METHODS: Ligation of the splenic vein was used to induce cong...AIM: To discuss the safety, feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation (MWA). METHODS: Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens, and microwave ablation was performed 2-4 h later. A total of 56 ablation points were ablated and the ablation powers were 30-100 W. The ablation time (1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 min) was performed at a power of 60 W. After ablation, the ablation size was measured in pigs A, C, D and E and spleen resection. In pig B, the ablation size was measuredand 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation. Pig B was killed 1 wk later and the ablation points were sent for pathology analysis. Bleeding, tissue carbonization surrounding electrodes, and pathological changes were observed, and the effect on destruction volume relative to different ablation powers, times and positions was analyzed. RESULTS: The incidence of bleeding (only small amounts, < 20 mL) in the course of ablation was 5.4% (3/56) and was attributed to tissue carbonization surrounding electrodes, which also exhibited an incidence of 5.4% (3/56). The destruction volume was influenced by different ablation powers, times and points. It showed that the ablation lesion size increased with increased ablation time, from 1 to 10 min, when the ablation power was 60 W. Also, the ablation lesion size increased with the increase of ablation power, ranging from 30 to 100 W when the ablation time was set to 3 min. A direct correlation was seen between the destruction volume and ablation time by the power of 60 W (r = 0.97542, P < 0.0001, and also between the destruction volume and ablation powers at an ablation time of 3 min (r = 0.98258, P < 0.0001). The destruction volume of zone Ⅱ (the extra-2/3 part of the spleen, relative to the fi rst or second class vascular branches), which was near the hilum of the spleen, was noteably larger than the destruction volume of zoneⅠ(the intra-1/3 part of the spleen) which was distal from the hilum of the spleen (P = 0.0015). Pathological changes of ablation occurring immediately and 1 wk after MWA showed large areas of coagulation. Immediately following ablation, intact spleen tissues were observed in the areas of coagulation necrosis, mainly around arterioles, and there were no obvious signs of hydropsia and inflammation, while 1 wk following the ablation, the coagulation necrosis was well distributed and complete, as many nuclear fragmentations were detected, and there were obvious signs of hydropsia and inflammation.CONCLUSION: In vivo treatment of congestion and tumescence in the spleen using microwave ablation of water-cooled antenna is a safe and feasible method that is minimally invasive.展开更多
The hybrid genetic algorithm is utilized to facilitate model parameter estimation.The tri-dimensional compression tests of soil are performed to supply experimental data for identifying nonlinear constitutive model of...The hybrid genetic algorithm is utilized to facilitate model parameter estimation.The tri-dimensional compression tests of soil are performed to supply experimental data for identifying nonlinear constitutive model of soil.In order to save computing time during parameter inversion,a new procedure to compute the calculated strains is presented by multi-linear simplification approach instead of finite element method(FEM).The real-coded hybrid genetic algorithm is developed by combining normal genetic algorithm with gradient-based optimization algorithm.The numerical and experimental results for conditioned soil are compared.The forecast strains based on identified nonlinear constitutive model of soil agree well with observed ones.The effectiveness and accuracy of proposed parameter estimation approach are validated.展开更多
Biomass in the form of nutshell, hay of catkin, wheat straw and linseed residue in particles have been pyrolyzed in laboratory scale fixed bed reactor which yielded liquid oil, solid char and gas. The variation of oil...Biomass in the form of nutshell, hay of catkin, wheat straw and linseed residue in particles have been pyrolyzed in laboratory scale fixed bed reactor which yielded liquid oil, solid char and gas. The variation of oil yield for different biomass feedstock with reactor bed temperature and feed size is presented in this paper. A maximum liquid yield of 55 wt% of dry feedstock is obtained at an optimum temperature of 500℃ for a feed size of 300-600μm with a running time of 55 min for nutshell as the feedstock while the minimum liquid oil yield is found to be 30 wt% of feedstock at an optimum temperature of 400℃ for a feed size of 2.36 mm with a running time of 65 min for linseed residue as the feedstock. A comparison on the product yields is highlighted in this study. The pyrolysis liquid products are characterized and compared for some of the fuel properties like HHV (higher heating value), viscosity, density and specific gravity.展开更多
Underground contamination by non-aqueous phase liquids (NAPLs) becomes increasingly serious. Rapid and reliable detection of contaminated zone and degree is the first step to site remediation. In this paper, diesel an...Underground contamination by non-aqueous phase liquids (NAPLs) becomes increasingly serious. Rapid and reliable detection of contaminated zone and degree is the first step to site remediation. In this paper, diesel and fine sand are used as experiment materials to investigate the applicability of using time-domain reflectometry (TDR) to detect LNAPLs contamination. The major work includes: measurement of dielectric constant and electrical conductivity for the diesel-water-air-sand mixtures; measurement of reflection waveform and dielectric constant for specimens with a diesel contaminated layer being sandwiched in sand. The experimental results show the followings: A significant decrease in both dielectric constant and electrical conductivity is observed for the diesel-water-air-sand mixtures when diesel displaces the pore water, and the content of diesel can be calculated by the model; insignificant change in dielectric properties is measured when diesel only displaces the pore gas; when the diesel contaminated sand is sandwiched between two saturated sand layers, the interfaces of the diesel contaminated layer can be identified by analyzing the reflection waveform; for field application, TDR method is valid for the case that LNAPLs seep into saturated sand layer, and the applicability of TDR method in vadose zone depends on the initial saturation of the sand layer. The findings obtained in this paper provide a guidance for the use of TDR for the field investigation of NAPLs contaminated site.展开更多
基金Supported by Guangdong Provincial Science and Technology FundGuangdong Provincial Scientifi c Project Grant
文摘AIM: To discuss the safety, feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation (MWA). METHODS: Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens, and microwave ablation was performed 2-4 h later. A total of 56 ablation points were ablated and the ablation powers were 30-100 W. The ablation time (1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 min) was performed at a power of 60 W. After ablation, the ablation size was measured in pigs A, C, D and E and spleen resection. In pig B, the ablation size was measuredand 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation. Pig B was killed 1 wk later and the ablation points were sent for pathology analysis. Bleeding, tissue carbonization surrounding electrodes, and pathological changes were observed, and the effect on destruction volume relative to different ablation powers, times and positions was analyzed. RESULTS: The incidence of bleeding (only small amounts, < 20 mL) in the course of ablation was 5.4% (3/56) and was attributed to tissue carbonization surrounding electrodes, which also exhibited an incidence of 5.4% (3/56). The destruction volume was influenced by different ablation powers, times and points. It showed that the ablation lesion size increased with increased ablation time, from 1 to 10 min, when the ablation power was 60 W. Also, the ablation lesion size increased with the increase of ablation power, ranging from 30 to 100 W when the ablation time was set to 3 min. A direct correlation was seen between the destruction volume and ablation time by the power of 60 W (r = 0.97542, P < 0.0001, and also between the destruction volume and ablation powers at an ablation time of 3 min (r = 0.98258, P < 0.0001). The destruction volume of zone Ⅱ (the extra-2/3 part of the spleen, relative to the fi rst or second class vascular branches), which was near the hilum of the spleen, was noteably larger than the destruction volume of zoneⅠ(the intra-1/3 part of the spleen) which was distal from the hilum of the spleen (P = 0.0015). Pathological changes of ablation occurring immediately and 1 wk after MWA showed large areas of coagulation. Immediately following ablation, intact spleen tissues were observed in the areas of coagulation necrosis, mainly around arterioles, and there were no obvious signs of hydropsia and inflammation, while 1 wk following the ablation, the coagulation necrosis was well distributed and complete, as many nuclear fragmentations were detected, and there were obvious signs of hydropsia and inflammation.CONCLUSION: In vivo treatment of congestion and tumescence in the spleen using microwave ablation of water-cooled antenna is a safe and feasible method that is minimally invasive.
基金Project(2007CB714006) supported by the National Basic Research Program of China Project(90815023) supported by the National Natural Science Foundation of China
文摘The hybrid genetic algorithm is utilized to facilitate model parameter estimation.The tri-dimensional compression tests of soil are performed to supply experimental data for identifying nonlinear constitutive model of soil.In order to save computing time during parameter inversion,a new procedure to compute the calculated strains is presented by multi-linear simplification approach instead of finite element method(FEM).The real-coded hybrid genetic algorithm is developed by combining normal genetic algorithm with gradient-based optimization algorithm.The numerical and experimental results for conditioned soil are compared.The forecast strains based on identified nonlinear constitutive model of soil agree well with observed ones.The effectiveness and accuracy of proposed parameter estimation approach are validated.
文摘Biomass in the form of nutshell, hay of catkin, wheat straw and linseed residue in particles have been pyrolyzed in laboratory scale fixed bed reactor which yielded liquid oil, solid char and gas. The variation of oil yield for different biomass feedstock with reactor bed temperature and feed size is presented in this paper. A maximum liquid yield of 55 wt% of dry feedstock is obtained at an optimum temperature of 500℃ for a feed size of 300-600μm with a running time of 55 min for nutshell as the feedstock while the minimum liquid oil yield is found to be 30 wt% of feedstock at an optimum temperature of 400℃ for a feed size of 2.36 mm with a running time of 65 min for linseed residue as the feedstock. A comparison on the product yields is highlighted in this study. The pyrolysis liquid products are characterized and compared for some of the fuel properties like HHV (higher heating value), viscosity, density and specific gravity.
基金supported by the National High Technology Research and Development Program of China ("863" Project) (Grant No.2012AA062601)the National Natural Science Foundation of Major International Cooperation Projects (Grant No. 51010008)
文摘Underground contamination by non-aqueous phase liquids (NAPLs) becomes increasingly serious. Rapid and reliable detection of contaminated zone and degree is the first step to site remediation. In this paper, diesel and fine sand are used as experiment materials to investigate the applicability of using time-domain reflectometry (TDR) to detect LNAPLs contamination. The major work includes: measurement of dielectric constant and electrical conductivity for the diesel-water-air-sand mixtures; measurement of reflection waveform and dielectric constant for specimens with a diesel contaminated layer being sandwiched in sand. The experimental results show the followings: A significant decrease in both dielectric constant and electrical conductivity is observed for the diesel-water-air-sand mixtures when diesel displaces the pore water, and the content of diesel can be calculated by the model; insignificant change in dielectric properties is measured when diesel only displaces the pore gas; when the diesel contaminated sand is sandwiched between two saturated sand layers, the interfaces of the diesel contaminated layer can be identified by analyzing the reflection waveform; for field application, TDR method is valid for the case that LNAPLs seep into saturated sand layer, and the applicability of TDR method in vadose zone depends on the initial saturation of the sand layer. The findings obtained in this paper provide a guidance for the use of TDR for the field investigation of NAPLs contaminated site.