“书房一角”:周作人阅读史初探

要摆脱种种主义的标签或立场之争,空手进入周作人的思想世界,最有效的方式是从他读过的书入手,清理这些书在他精神生活中留下的痕迹,哪些构成他应对危机的思想资源。本文并非目录学意义上的文献整理,意在通过揭露苦雨斋的书房一角,探究周作人所谓"杂学"的来源,重点考察其不合时宜的思想立场背后的知识谱系。基于苦雨斋藏书的保存现状,理想的研究路径是采取文本内证与实物搜讨相结合的"二重证据法",以竭泽而渔的版本目录学整理为基础,最终导向个人思想史及精神生活史的探究。之所以从阅读史的角度进入,是为了让自己"大于"研究对象,与其保持一种相对平等的对话关系。

作为“现代宏观叙事”的博物馆——评苏珊·皮尔斯《博物馆、实物和藏品:文化研究》(1993)

英国学者苏珊·皮尔斯是博物馆学研究的代表人物之一。她的代表作《博物馆、实物和藏品:文化研究》阐述了博物馆作为“现代宏观叙事”的研究视角。她区分了收藏家在特定的社会思潮中对实物的选择、博物馆在挑选实物入藏时对社会思潮的反馈,以及博物馆运用符号化的语言塑造了观众对“客观事实”和“永恒真理”的认知。将博物馆作为叙事本身,而不是优化叙事的手段,打开了将博物馆置于其所处的社会文化语境中进行综合考量的研究空间。皮尔斯的研究可以启发我国开展博物馆学基础研究。

Pharmacokinetics of radioimmunotherapeutic agent of direct labeling mAb ^(188)Re-HAb18

AIM:To labed Anti-hepatoma monoclonal antibody(mAb) fragment HAb18 F(ab')_2 was labeled with 188 Re for the pharmacokinetic model of ^(188)Re-HAb18 F(ab')_2 and to evaluate its pharmacokinetic parameters in hepatoma- bearing nude mice. METHODS:HAb18 F(ab')_2 was directly labeled with ^(188)Re using 2-mercaptoethanol(2-ME)as reducing agents. Labeling efficiency and immunoreactivity of ^(188)Re-HAb18 F (ab')_2 were evaluated by Whatman 3MM paper chromatography and live cell assay,respectively. Biodistribution analysis was also conducted in nude mice bearing human hepatoma in which animals were sacrificed at different time points(1,4,18,24 and 24h)after ^(188)Re-HAb18 F(ab')_2 was injected through tail-vein into hepatoma-bearing nude mice.The blood and radioactivity of organs and mass were measured.The concentrations of ^(188)Re-HAb18 F(ab')_2 were evaluated with a pharrnacokinetic 3P97 software. RESULTS:The optimum labeling efficiency and immunoreactive fraction were 91.7% and 0.78%, respectively.The parameters of ^(188)Re-HAb18 F(ab')_2 were: T_(1/2),2.29h;Vd,1.49×10^(-9)L·Bq^(-1);AUC,20.49×10~9Bq·h· L^(-1);CL,0.45×10^(-3)L·h^(-1).^(188)Re-HAb18 F(ab')_2 could locate specially in hepatoma with high selective reactivity of HAb18 F(ab')_2.^(188)Re-HAbl8 F(ab')_2 was mainly eliminated by kidney.The maximal tumor to blood ratio was at 48h,and maximal tumor to liver ratio was at 18h. CONCLUTION:The pharmacokinetics of ^(188)Re-HAb18 F(ab')_2 fit a I-compartment model.^(188)Re-HAb18 F(ab')_2 can be uptaken selectively at the hepatoma site.

A case study of excessive vibrations inside buildings due to an underground railway:Experimental tests and theoretical analysis

Excessive vibrations inside buildings in the Lihu New Village caused by the Shenzhen Metro Line 2 underground railway were investigated by conducting analyses of the tunnel,the track irregularities,the stiffness of the fastening system,and the vibrations of the track system and the building at different speeds.A numerical simulation based on the dynamic coupling theory of the vehicle-track system was used to verify the experimental results.Suitable countermeasures were investigated.The results show that rail corrugation is the primary reason for the excessive vibration,and an increase in the stiffness of the vertical fastening system is the secondary reason.The solution was to eliminate the rail corrugation using rail grinding and decrease the vertical stiffness by changing the fastening system.The results of this study provide references for solving vibration problems caused by rail lines.

Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic inflammatory action with increase of mucosal integrity

AIM： To examine the effect of Eubacteriuro Iiroosuro （E.Iiroosuro） on colonic epithelial cell line in vitro, and to evaluate the effect of E.limosum on experimental colitis.METHODS： E.Iimosum was inoculated anaerobically and its metabolites were obtained. The growth stimulatory effect of the E.limosum metabolites on T84 cells was evaluated by SUDH activity, and the anti-inflammatory effect by IL-6 production. The change in mRNA of toll like receptor 4 （TLR4） was evaluated by real time PCR. Colitis was induced by feeding BALB/C mice with 2.0% dextran sodium sulfate. These mice received either 5% lyophilized E.lirnosum （n=7） or control diet （n=7）. Seven days after colitis induction, clinical and histological scores, colon length, and cecal organic acid levels were determined.RESULTS： The E.Iimosum produced butyrate, acetate, propionate, and lactate at 0.25, 1.0, 0.025 and 0.07 retool/L, respectively in medium. At this concentration, each acid had no growth stimulating activity on T84 cells; however, when these acids were mixed together at the above levels, it showed significantly high activity than control. Except for lactate, these acids significantly attenuated IL-6 production at just 0.1 mmol/L. In addition, under TNF-α stimulation, butyrate attenuated the production of TLR4 mRNA. The treatment with E.limosum significantly attenuated clinical and histological scores of colitis with an increase of cecal butyrate levels, compared with the control group.CONCLUSION： E.limosum can ameliorate experimental colonic inflammation. In part, the metabolite of E.lirnosurn, butyrate, increases mucosal integrity and shows anti-inflammatory action modulation of mucosal defense system via TLR4.

Lansoprazole prevents experimental gastric injury induced by non-steroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage

AIM:This study investigated the mechanisms of protection afforded by the proton pump inhibitor lansoprazole against gastric injury induced by different non-steroidal anti-inflammatory drugs (NSAIDs) in rats. METHODS: Male Sprague-Dawley rats were orally treated with indomethacin (100 μmol/kg), diclofenac (60 μmol/kg), piroxicam (150 μmol/kg) or ketoprofen (150 μmol/kg). Thirty minutes before NSAIDs, animals were orally treated with lansoprazole 18 or 90 umol/kg. Four hours after the end of treatments, the following parameters were assessed: gastric mucosal PGE2, malondialdehyde (MDA), myeloperoxidase (MPO) or non-proteic sulfhydryl compounds (GSH) levels; reverse transcription-polymerase chain reaction (RT-PCR) of mucosal COX-2 mRNA; gastric acid secretion in pylorus-ligated animals; in vitro effects of lansoprazole (1-300 μmol/L) on the oxidation of low density lipoproteins (LDLs) induced by copper sulphate. RESULTS: All NSAIDs elicited mucosal necrotic lesions which were associated with neutrophil infiltration and reduction of PGE2 levels. Increments of MPO and MDA contents, as well as a decrease in GSH levels were detected in the gastric mucosa of indomethacin- or piroxicam-treated animals. Indomethacin enhanced mucosal cyclooxygenase-2 expression, while not affecting cyclooxygenase-1. At the oral dose of 18 μmol/kg lansoprazole partly counteracted diclofenac-induced mucosal damage, whereas at 90 μmol/kg it markedly prevented injuries evoked by all test NSAIDs. Lansoprazole at 90 μmol/kg reversed also the effects of NSAIDs on MPO, MDA and GSH mucosal contents, without interfering with the decrease in PGE2 levels or indomethacin-induced cyclooxygenase-2 expression. However, both lansoprazole doses markedly inhibited acid secretion in pylorus-ligated rats. Lansoprazole concentration-dependently reduced the oxidation of LDLs in vitro. CONCLUSION: These results suggest that, besides the inhibition of acid secretion, lansoprazole protection against NSAID-induced gastric damage depends on a reduction in mucosal oxidative injury, which is also responsible for an increment of sulfhydryl radical bioavailability. It is also suggested that lansoprazole does not influence the down-regulation of gastric prostaglandin production associated with NSAID treatment.

Plant Test of Industrial Waste Disposal in a Cement Kiln

Destruction of industrial waste in cement rotary kilns (CRKs) is an alternative technology for the treatment of certain types of industrial waste (IW). In this paper, three typical types of industrial wastes were co-incinerated in the CRK at Beijing Cement Plant to determine the effects of waste disposal (especially solid waste disposal) on the quality of clinker and the concentration of pollutants in air emission. Experimental results show that (1) waste disposal does not affect the quality of clinker and fly ash, and fly ash after the IW disposal can still be used in the cement production, (2) heavy metals from IW are immobilized and stabilized in the clinker and cement, and (3) concentration of pollutants in air emission is far below than the permitted values in the China National Standard-Air Pollutants Emission Standard (GB 16297-1996).

Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals

AIM： To evaluate the effects of osthole on fatty liver, and investigate the possible mechanism. METHODS： A quail model with hyperlipidemic fatty liver and rat model with alcoholic fatty liver were set up by feeding high fat diet and alcohol, respectively. These experimental animals were then treated with osthole 5-20 mg/kg for 6 wk, respectively. Whereafter, the lipid in serum and hepatic tissue, and coefficient of hepatic weight were measured. RESULTS： After treatment with osthole the levels of serum total cholesterol （TC）, triglyceride （TG）, lower density lipoprotein-cholesterol （LDL-C）, coefficient of hepatic weight, and the hepatic tissue contents of TC and TG were significantly decreased. The activity of superoxide dismutase （SOD） in liver was improved. In alcohol-induced fatty liver rats, the level of malondialdehyde （MDA） in liver was decreased. In high fat-induced fatty liver quails, glutathione peroxidase （GSH-PX） in liver was significantly improved. The histological evaluation of liver specimens demonstrated that the osthole dramatically decreased lipid accumulation. CONCLUSION： These results suggested that osthole had therapeutic effects on both alcohol and high fatinduced fatty liver. The mechanism might be associated with its antioxidation.

The flocculation research on treating suspended solids contained mine drainage through goaf

Mine drainage could be filtered and purified through goaf. This innovative technique shows merits, such as high treatment efficiency, remarkable economic benefit and extensive wastewater recycle use. However, it was detected that capacities of purifying mine drainage for goaf were decreased after a period of application. As a result, the effluent could not meet the standard of recycle water. To solve the problem, coagulant was considered to add into mine drainage reducing its high turbid degrees to certain level. After the preliminary flocculation treatment, mine drainage was piped into goaf to purify. In this way, the load of goaf was eased up. Its usage time was also prolonged. Therefore, this paper carried out the coagulation-flocculation jar test for mine drainage to discuss the flocculation parameters. By the experiment, 10 % iron trichloride is selected from four inorganic coagulants as the optimum coagulant. The optimum dose, PH value and sedirs6-7 and 25 min. Velocity mentation time are respectively 2 mL per 800 mL Wastewater gradient G during the process of mixing and reaction is 696 .And the value of GT is 6.264 × 10^5. The values of G and GT will supply the basis for the design of flocculation pool in the project. The flocculation parameters will be significant for the reference of practice.

Effects of garlicin on apoptosis in rat model of colitis

AIM： To investigate the effects of garlicin on apoptosis and expression of bcl-2 and bax in lymphocytes in rat model of ulcerative colitis （UC）. METHODS： Healthy adult Sprague-Dawley rats of both sexes, weighing 180±30 g, were employed in the present study. The rat model of UC was induced by 2,4,6-trinitrobenzene sulfonic acid （TNBS） enema. The experimental animals were randomly divided into garlicin treatment group （including high and low concentration）, model control group, and normal control group. Rats in garlicin treatment group and model control group received intracolic garlicin daily at doses of 10.0 and 30.0 mg/kg and equal amount of saline respectively 24 h after colitis model was induced by alcohol and TNBS co-enema. Rats in normal control group received neither alcohol nor only TNBS but only saline enema in this study. On the 28^th d of the experiment, rats were executed, the expression of bd-2 and bax protein was determined immunohistochemically and the apoptotic cells were detected by the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate fluorescence nick end labeling （TUNEL） method. At the same time, the rat colon mucosal damage index （CMDI） was calculated. RESULTS： In garlicin treatment group, the positive expression of bcl-2 in lymphocytes decreased and the number of apoptotic cells was more than that in model control group, CMDI was lower than that in model control group. The positive expression of bax in lymphocytes had no significant difference. CONCLUSION： Garlicin can protect colonic mucosa against damage in rat model of UC induced by TNBS enema.

Lie-Form Invariance of the Nonholonomic System of Relative Motion in Event Space

In this paper, the Lie-form invariance of a nonholonomic system of relative motion in event space is studied. Firstly, the definition and the criterion of the Lie-form invariance of the nonholonomic system of relative motion in event space is given. Secondly, the Hojman conserved quantity and a new type of conserved quantity deduced from the Lie-form invariance are obtained. An example is given to illustrate the application of the results.

Thermal Phase in Bubbling Geometries

We use matrix model to study thermal phase in bubbling half-BPS type liB geometries with SO（4） × SO（4） symmetry. Near the horizon limit, we find that thermal vacua of bubbling geometries have disjoint parts, and each part is one kind of phase of the thermal system. We connect the thermal dynamics of bubbling geometries with one-dimensional fermions thermal system. Finally, we try to give a new possible way to resolve information loss puzzle.

Implementation of Non-local Operations for High-Dimensional Systems Through Qubit Quantum Channels

We propose a method to implement a kind of non-local operation between spatially separated two systems with high dimensions by using only a low-dimensional qubit quantum channel and 2-bit classical communication. For qutrit systems, we further show the creation of non-local maximally entangled state and the construction of the non-local quantum XOR gate in terms of the obtained non-local operations as well as some single qutrit local gates.

Separation of Toluene Insoluble Matter from Syncrude Coker Heavy Gas Oil

Toluene insoluble matter (TIM) in coker heavy gas oil (CHGO) from oil sands bitumen is harmful to the downstream hydrotreating, and it may be difficult to be removed by conventional filtration. In order to determine its origin, the TIM must first be separated from CHGO for characterization. Two techniques are described to accomplish this goal. In the ultra-centrifugation approach used in this work, CHGO is blended with a miscible liquid and centrifuged under 366000 G (gravity) force. Through this procedure toluene and hexane diluents yielded TIM contents of 24μg·g-1 and 88μg·g-1 respectively. In an alternative simplified procedure, the initial ultra-centrifugation step is omitted. Several different solvents are evaluated for use as diluents but, in each case, toluene is still used in the subsequent washing steps. TIM contents determined by this method range from 23 to about 200μg·g-1. The amount of TIM separated by means of this method depends primarily on the initial diluent used. Other conditions, such as diluent-oil ratio, water-oil ratio, mixing time, temperature and water pH value, are also studied.

Effects of iron manipulation on trace elements level in a model of colitis in rats

AIM: Trace elements (TE) metabolism is altered in inflammatory bowel diseases. TE (zinc and copper) are constituents of antioxidant enzymes. Iron is involved in the pathogenesis of chronic inflammation. The aim was to evaluate zinc and copper status and the effects of iron manipulation in experimental colitis.METHODS: Twenty-four male Sprague-Dawley rats were divided into four groups: standard diet, iron-deprived diet,iron-supplemented diet, and sham-treated controls.Macroscopic damage was scored. DNA adducts were measured in the colon. Liver and colonic concentration of TE were measured.RESULTS: Macroscopic damage was reduced in irondeprived groups and increased in iron-supplemented rats.Damage to the DNA was reduced in iron-deprived groups and increased in iron-supplemented groups. Liver and colonic iron concentrations were reduced in iron-deprived and increased in iron-supplemented rats. Liver zinc concentration was reduced after supplementation whereas colonic levels were similar in controls and treated rats. Liver copper concentration was reduced in all the colitic groups except in the iron-supplemented group whereas colonic concentration was increased in iron-deprived rats.CONCLUSION: Iron deprivation diminishes the severity of DNBS colitis while supplementation worsens colitis. Zinc and copper status are modified by iron manipulation.

Microhabitat use by white-footed mice Peromyscus leucopus in forested and old-field habitats occupied by Morrow's honeysuckle Lonicera morrowii

We quantified microhabitat use by white-footed mice Peromyscus leucopus in forest and old-field habitats occupied by Morrow＇ s honeysuckle Lonicera morrowii, an invasive exotic shrub imported from Japan. Microhabitat characteristics were compared between trails used by mice （ n = 124） and randomly selected trails （ n = 127） in 4 study plots located at Fort Necessity National Battlefield, Farmington, Pennsylvania, USA. We compared 10 mierohabitat variables between used and random trails using non-metric multidimensional scaling （NMDS） and classification and regression tree （CART） analysis. Trails used by mice were statistically different from randomly selected trails in both forested plots （ P 〈 0. 008） and old-field plots （ P 〈 0. 001 ）. In the forested plots, trails of white-footed mice were more often associated with a greater percent cover （% cover） of coarse woody debris （CWD） than were randomly selected trails. In the old-field plots, mouse trails were commonly characterized by having a lower % cover of exotic herbaceous vegetation, a greater % cover of shrubs, and a greater % cover of Morrow＇ s honeysuckle than randomly selected trails. Our study indicates that white-footed mice do not move randomly and prefer areas of high structural complexity, thereby showing significant microhabitat preference. The preference of white-footed mice for areas with a relatively high percent cover of Morrow＇s honeysuckle could 1 ） be a factor in the aggressive nature of the exotic honeysuckle shrub＇s spread throughout the Battlefield or 2） cause the shrub to spread even faster into adjacent areas not yet occupied by Morrow＇ s honeysuckle

Experimental Study on Vertical Dilute Phase Gas Conveying

An experimental study of vertical gas conveying of Geldart-D powder as a dilute phase is performed in a pipe of length 22m and internal diameter 0.05m using a fluidized blow tank at gas velocity ranging from 5m.S-1 to 13m.s-1 and loading ratio up to about 30. The characteristics of gas conveying, such as pressure drop, the choking velocity and the minimum primary velocity of the fluidized blow tank, are discussed in detail.

Influence of material’s cyclic deformation behaviour on fatigue crack growth threshold

To investigate the relation between material＇s cychc plastic behaviour and fatigue crack growth, a new model is proposed. The model incorporated the two intrinsic properties of material＇ s cyclic plastic and crack tip＇ s deformation dislocation to interpret fatigue crack threshold. The relation between material＇ s cyclic hardening parameters （cyclic hardening amplitude and cyclic hardening rate） and fatigue threshold is studied. Fatigue threshold is determined based on the dislocation-free zone （DFZ） model, the theory of cohesive zone and the cyclic deformation behaviour. The results show that fatigue threshold increases with the decrease of the amplitude of cyclic hardening and is independent of cyclic hardening rate, but fatigue crack growth rate increases with the increase of cyclic hardening rate.

Automatic Spike Sorting Based on Robust Clustering

The collected spikes from extracellular recordings usually contain noisy data and outliers, which make it difficult to separate them. A method for spike sorting based on robust clustering is proposed to deal with the problem. The clustering method combines the advantage of fuzzy clustering and robust statistical estimators. The number of dusters is obtained by fuzzy cluster validity. In order to reduce the influence of outliers, the validity index is calculated using the weighting intra-cluster distances. The proposed method is suitable to separate neural spikes in the presence of noisy data and outfiers. The experiment on real data shows its performance.

Theoretical and Experimental Studies on Interactions of Cationic-Anionic Surfactants

Typical cationic and anionic surfactants were chosen and their interactions were calculated by quantum chemical method. Interaction energies are -0.2378 kJ·mol-1, -3.3394kJ·mol-1 and 0.1204kJ·mol-1 for the molecular pairs with fluocarbon and hydrocarbon chain: C4H10/C5H12, C4F10/C5H12, and C4F10 /C5F12, respectively. When hydrophilic group with cationic and anionicions is introduced, interaction energies are -287.40kJ·mol-1, -311.18kJ·mol-1 and -345.83kJ·mol-1. The results show that there is strong static interaction between cationic and anionic surfactants. It has been predicted that mixed monolayer may be formed and surface activity is enhanced favorably, especially for mixtures of cationic and anionic surfactants with fluocarbon and hydrocarbon chains. The anionic surfactants, sodium octadecylbenzenesulfonate perfluopolyetherbenzenesulonate(ANF-I) was synthesized, mixture effects of ANF-I with sodium octadecylbenzenesulfonate or dodecyldimethyl benzylammonium bromide were studied. The results indicate that the efficiency of mixing increased and the theoretical prediction was testified. These results can provide useful information for the design of new surfactants.