In the last decades, a trend towards a worldwide aging has been reported and diseases which are common in the elderly people would have important implications in clinical practice. Aortic stenosis （AS） is perhaps th...In the last decades, a trend towards a worldwide aging has been reported and diseases which are common in the elderly people would have important implications in clinical practice. Aortic stenosis （AS） is perhaps the most common and most often cause of sudden death among valvular heart diseases. Its prevalence is low among adults aged 〈 60 years, but increases to almost 10% in adults ≥ 80 years.[2] Since the degenerative calcific disease represents the lead- ing cause of AS in developed countries, the improved understanding on its pathogenesis （atherosclerotic processes and/or skeleton key） may offer potentially new targets for preventing and inhibiting AS development and progres- sion.[3] Patients with AS are generally asymptomatic for a prolonged period and the development of symptoms is a critical point in the natural history. Indeed, the prognosis changes dramatically with the onset of symptoms of angina,展开更多
It has always been very important throughout the centuries for legislative institutions and police organizations to watch over different media and genres as instruments of conspiracy of criminals, members of organized...It has always been very important throughout the centuries for legislative institutions and police organizations to watch over different media and genres as instruments of conspiracy of criminals, members of organized crime, and terroristic groups in order to recognize conspiracy contents and to evaluate them systematically （intelligence work）. With the help of special methods-design, it is possible to analyze the functions and strategies of this specific sometimes open or undercover used languages of Rotwelsch, Argot, Fenya, terrorist and Jihadi groups. A very significant example is the history of Jihadi Internet as a cyber-planning tool： single websites （until 2001）, expansion and professionalization （2001-2007） and severe surveillance, distrust and new social media （after 2008 especially because of 9/11）. Since it has become clear that the National Security Agency （NSA） conducts severe intelligence research in the field of E-mail-traffic and chats, the demand of crypto-programs has grown. It is better in this situation to return to face-to-face-communication. Legislative institutions and police have to study these functions and strategies in order to practice the best fitting counter-action against crime and terrorism.展开更多
In this paper,we utilize the variational limiting equilibrium(LE) procedure to theoretically determine the slope stability of homogeneous coral sand in the South China Sea.By establishing a reasonable functional and c...In this paper,we utilize the variational limiting equilibrium(LE) procedure to theoretically determine the slope stability of homogeneous coral sand in the South China Sea.By establishing a reasonable functional and calculating its extremum,we can deduce the stability factor of a coral reef identical to that obtained by upper bound analysis.To determine the accuracy of the results obtained using the variational LE procedure,we present some classical examples of homogeneous sand slopes without a hard shell and compare our results with those obtained by the upper bound theorem of plasticity.A series of extensive calculations and comparisons reveal that the results obtained by our proposed analysis method and those obtained using classical methods are slightly different,but the variational results are believable.On the other hand,our method solves some stability factors for reef slopes covered with a hard shell,which indicates that the existence of a hard reef shell may significantly enhance the stability of a reef slope,and that there is strong nonlinear relationship between reef stability and the mechanical characteristics of the reef shell,such as its thickness and strength.Finally,based on the variational results presented in this paper,we present a useful chart that offers a convenient and straightforward way to determine the maximum stability factor of reef slopes.Taking into account the influence of the hard reef shell,we found that,in some limit equilibrium cases,the limit stability factor and critical height of a coral slope could be improved significantly.Therefore,this issue deserves careful attention in engineering practice.展开更多
The natural history of Barrett's esophagus (BE) is difficult to quantify because,by definition,it should describe the course of the condition if left untreated.Pragmatically,we assume that patients with BE will re...The natural history of Barrett's esophagus (BE) is difficult to quantify because,by definition,it should describe the course of the condition if left untreated.Pragmatically,we assume that patients with BE will receive symptomatic treatment with acid suppression,usually a proton pump inhibitor,to treat their heartburn.This paper describes the development of complications of stricture,ulcer,dysplasia and adenocarcinoma from this standpoint.Controversies over the definition of BE and its implications in clinical practice are presented.The presence of intestinal metaplasia and its relevance to cancer risk is discussed,and the need to measure the extent of the Barrett's epithelium (long and short segments) using the Prague guidelines is emphasized.Guidelines and international consensus over the diagnosis and management of BE are being regularly updated.The need for expert consensus is important due to the lack of randomized trials in this area.After searching the literature,we have tried to collate the important studies regarding progression of Barrett's to dysplasia and adenocarcinoma.No therapeutic studies yet reported show a clear reduction in the development of cancer in BE.The effect of pharmacological and surgical intervention on the natural history of Barrett's is a subject of ongoing research,including the Barrett's Oesophagus Surveillance Study and the aspirin and esomeprazole cancer chemoprevention trial with interesting results.The geographical variation and the wide range of outcomes highlight the difficulty of providing an individualized risk profile to patients with BE.Future studies on the interaction of genome wide abnormalities in Barrett's and their interaction with environmental factors may allow individualization of the risk of cancer developing in BE.展开更多
In this paper, we conduct research on the new mode of computer education based on project driving methodology and teaching practice. Computer education is an important part in college education, application of compute...In this paper, we conduct research on the new mode of computer education based on project driving methodology and teaching practice. Computer education is an important part in college education, application of computer technology can effectively cultivate students＇ ability and quality of information. Collaborative project teaching method of the implementation of the method can make students accept knowledge by only listen into doing which will not only enhance the students＇ ability but help teachers obtain better feedback as well which is meaningful and necessary. The proposed methodology and education pattern is proven to be effective and feasible.展开更多
After the 2008 financial crisis, reality prompts people to reflect on the traditional theoretical frameworks of economics and the practical experiences based on macro-control and "demand management." The new...After the 2008 financial crisis, reality prompts people to reflect on the traditional theoretical frameworks of economics and the practical experiences based on macro-control and "demand management." The new reality also stimulates innovative efforts to "connect theory with practice" and leads academia and decision-makers to pay unprecedented attention to "supply management" regulation and structural supply-side reforms. Based on the theoretical innovation of the "new supply-side economics," this paper systematically discusses China's supply-side reform and its related issues from four levels—the innovation of closely connecting theory with practice, the problem-oriented innovation of re-making the momentum system under the new normal, the innovation for overall and long-term goals based on comprehensive planning and systematic engineering, and the innovation of institutional supply centered on reforms and modernization.展开更多
Praxis and doctrine agree on the importance of innovation for the competitiveness and profitability of the firm. Innovation is considered as a leverage to start a virtuous circle that improves company performance and,...Praxis and doctrine agree on the importance of innovation for the competitiveness and profitability of the firm. Innovation is considered as a leverage to start a virtuous circle that improves company performance and, consequently, reduce financial constraints for its development. Being creative is definitely the first mechanism that leads to innovation. Creativity spreads from both the individuals that work in the firm and from the social processes and contextual factors that characterize individual relationships within the company. Relational capital is the second mechanism that brings innovation. Relationships with clients, suppliers, competitors, producers of complementary products, public and private research institutions provide creative elements that, once screened, give rise to innovation. The first mechanism requires the firm to be creative on its own as innovations come directly from within the organization （＂closed innovation＂ model）. In the second, the firm must get in touch with potentially innovative idea~ coming from outside （＂open innovation＂ model）. Doctrine and praxis point out that firms, which do not stop at the first mechanism of innovation, turn out to be more innovative. The paper is structured as follows. In the first part, a theoretical framework is provided, describing the main findings, in the literature, in terms of relationships among innovation, creativity and relational capital. The second part is based on the analysis of two case studies. The first case （Coswell）, the very different degree of success （in terms of generated income） of its products seems to be tightly related on how much ＂relational capital＂ is ＂inside＂ the innovation. In the second case （Pastificio Rana） shows that innovation resulting from relational capital allows the company to excel against its far bigger and financially superior competitors.展开更多
Along with the society＇ s stronger demand for practices of students of human resources management （HRM）, the construction of practice teaching system shall be the key channel for the cultivation of practice talents...Along with the society＇ s stronger demand for practices of students of human resources management （HRM）, the construction of practice teaching system shall be the key channel for the cultivation of practice talents, especially in local universities and institutions. Combining with the practice of HRM construction in Langfang Teachers University, based on the introduction about the necessity of construction of practice teaching system, the construction content, guarantee measures, and implementation effect of practice teaching system for the cultivation of applied talents of HRM are out forward in this paper, which is in favor of the cultivation of applied talents of HRM.展开更多
Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full powe...Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full power converter wind turbines is composed and the model validation based on actual field measurements is performed. The paper is based on the measurements obtained from the real short circuit test applied to connection point of observed wind farm. The presented approach for validating the composed model and fault ride-through （FRT） capability for the whole wind park is unique in overall practice and its significance and importance is described and analyzed.展开更多
the paper discusses the advantage and disadvantage of organic chemistry teaching mode of multimedia auxiliary university compared with traditional teaching mode. And combined with the author＇ s teaching practice the ...the paper discusses the advantage and disadvantage of organic chemistry teaching mode of multimedia auxiliary university compared with traditional teaching mode. And combined with the author＇ s teaching practice the paper sums up that the multimedia technology shall be used as the auxiliary method of traditional teaching to optimize classroom teaching, improve the classroom efficiency and reflect the true value of the multimedia auxiliary teaching.展开更多
Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morpho...Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.展开更多
文摘In the last decades, a trend towards a worldwide aging has been reported and diseases which are common in the elderly people would have important implications in clinical practice. Aortic stenosis （AS） is perhaps the most common and most often cause of sudden death among valvular heart diseases. Its prevalence is low among adults aged 〈 60 years, but increases to almost 10% in adults ≥ 80 years.[2] Since the degenerative calcific disease represents the lead- ing cause of AS in developed countries, the improved understanding on its pathogenesis （atherosclerotic processes and/or skeleton key） may offer potentially new targets for preventing and inhibiting AS development and progres- sion.[3] Patients with AS are generally asymptomatic for a prolonged period and the development of symptoms is a critical point in the natural history. Indeed, the prognosis changes dramatically with the onset of symptoms of angina,
文摘It has always been very important throughout the centuries for legislative institutions and police organizations to watch over different media and genres as instruments of conspiracy of criminals, members of organized crime, and terroristic groups in order to recognize conspiracy contents and to evaluate them systematically （intelligence work）. With the help of special methods-design, it is possible to analyze the functions and strategies of this specific sometimes open or undercover used languages of Rotwelsch, Argot, Fenya, terrorist and Jihadi groups. A very significant example is the history of Jihadi Internet as a cyber-planning tool： single websites （until 2001）, expansion and professionalization （2001-2007） and severe surveillance, distrust and new social media （after 2008 especially because of 9/11）. Since it has become clear that the National Security Agency （NSA） conducts severe intelligence research in the field of E-mail-traffic and chats, the demand of crypto-programs has grown. It is better in this situation to return to face-to-face-communication. Legislative institutions and police have to study these functions and strategies in order to practice the best fitting counter-action against crime and terrorism.
基金supported by the National Science and Technology Ministry(No.2014BAB16B03)the National Natural Science Foundation of China(No.5167 9224)
文摘In this paper,we utilize the variational limiting equilibrium(LE) procedure to theoretically determine the slope stability of homogeneous coral sand in the South China Sea.By establishing a reasonable functional and calculating its extremum,we can deduce the stability factor of a coral reef identical to that obtained by upper bound analysis.To determine the accuracy of the results obtained using the variational LE procedure,we present some classical examples of homogeneous sand slopes without a hard shell and compare our results with those obtained by the upper bound theorem of plasticity.A series of extensive calculations and comparisons reveal that the results obtained by our proposed analysis method and those obtained using classical methods are slightly different,but the variational results are believable.On the other hand,our method solves some stability factors for reef slopes covered with a hard shell,which indicates that the existence of a hard reef shell may significantly enhance the stability of a reef slope,and that there is strong nonlinear relationship between reef stability and the mechanical characteristics of the reef shell,such as its thickness and strength.Finally,based on the variational results presented in this paper,we present a useful chart that offers a convenient and straightforward way to determine the maximum stability factor of reef slopes.Taking into account the influence of the hard reef shell,we found that,in some limit equilibrium cases,the limit stability factor and critical height of a coral slope could be improved significantly.Therefore,this issue deserves careful attention in engineering practice.
文摘The natural history of Barrett's esophagus (BE) is difficult to quantify because,by definition,it should describe the course of the condition if left untreated.Pragmatically,we assume that patients with BE will receive symptomatic treatment with acid suppression,usually a proton pump inhibitor,to treat their heartburn.This paper describes the development of complications of stricture,ulcer,dysplasia and adenocarcinoma from this standpoint.Controversies over the definition of BE and its implications in clinical practice are presented.The presence of intestinal metaplasia and its relevance to cancer risk is discussed,and the need to measure the extent of the Barrett's epithelium (long and short segments) using the Prague guidelines is emphasized.Guidelines and international consensus over the diagnosis and management of BE are being regularly updated.The need for expert consensus is important due to the lack of randomized trials in this area.After searching the literature,we have tried to collate the important studies regarding progression of Barrett's to dysplasia and adenocarcinoma.No therapeutic studies yet reported show a clear reduction in the development of cancer in BE.The effect of pharmacological and surgical intervention on the natural history of Barrett's is a subject of ongoing research,including the Barrett's Oesophagus Surveillance Study and the aspirin and esomeprazole cancer chemoprevention trial with interesting results.The geographical variation and the wide range of outcomes highlight the difficulty of providing an individualized risk profile to patients with BE.Future studies on the interaction of genome wide abnormalities in Barrett's and their interaction with environmental factors may allow individualization of the risk of cancer developing in BE.
文摘In this paper, we conduct research on the new mode of computer education based on project driving methodology and teaching practice. Computer education is an important part in college education, application of computer technology can effectively cultivate students＇ ability and quality of information. Collaborative project teaching method of the implementation of the method can make students accept knowledge by only listen into doing which will not only enhance the students＇ ability but help teachers obtain better feedback as well which is meaningful and necessary. The proposed methodology and education pattern is proven to be effective and feasible.
文摘After the 2008 financial crisis, reality prompts people to reflect on the traditional theoretical frameworks of economics and the practical experiences based on macro-control and "demand management." The new reality also stimulates innovative efforts to "connect theory with practice" and leads academia and decision-makers to pay unprecedented attention to "supply management" regulation and structural supply-side reforms. Based on the theoretical innovation of the "new supply-side economics," this paper systematically discusses China's supply-side reform and its related issues from four levels—the innovation of closely connecting theory with practice, the problem-oriented innovation of re-making the momentum system under the new normal, the innovation for overall and long-term goals based on comprehensive planning and systematic engineering, and the innovation of institutional supply centered on reforms and modernization.
文摘Praxis and doctrine agree on the importance of innovation for the competitiveness and profitability of the firm. Innovation is considered as a leverage to start a virtuous circle that improves company performance and, consequently, reduce financial constraints for its development. Being creative is definitely the first mechanism that leads to innovation. Creativity spreads from both the individuals that work in the firm and from the social processes and contextual factors that characterize individual relationships within the company. Relational capital is the second mechanism that brings innovation. Relationships with clients, suppliers, competitors, producers of complementary products, public and private research institutions provide creative elements that, once screened, give rise to innovation. The first mechanism requires the firm to be creative on its own as innovations come directly from within the organization （＂closed innovation＂ model）. In the second, the firm must get in touch with potentially innovative idea~ coming from outside （＂open innovation＂ model）. Doctrine and praxis point out that firms, which do not stop at the first mechanism of innovation, turn out to be more innovative. The paper is structured as follows. In the first part, a theoretical framework is provided, describing the main findings, in the literature, in terms of relationships among innovation, creativity and relational capital. The second part is based on the analysis of two case studies. The first case （Coswell）, the very different degree of success （in terms of generated income） of its products seems to be tightly related on how much ＂relational capital＂ is ＂inside＂ the innovation. In the second case （Pastificio Rana） shows that innovation resulting from relational capital allows the company to excel against its far bigger and financially superior competitors.
文摘Along with the society＇ s stronger demand for practices of students of human resources management （HRM）, the construction of practice teaching system shall be the key channel for the cultivation of practice talents, especially in local universities and institutions. Combining with the practice of HRM construction in Langfang Teachers University, based on the introduction about the necessity of construction of practice teaching system, the construction content, guarantee measures, and implementation effect of practice teaching system for the cultivation of applied talents of HRM are out forward in this paper, which is in favor of the cultivation of applied talents of HRM.
文摘Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full power converter wind turbines is composed and the model validation based on actual field measurements is performed. The paper is based on the measurements obtained from the real short circuit test applied to connection point of observed wind farm. The presented approach for validating the composed model and fault ride-through （FRT） capability for the whole wind park is unique in overall practice and its significance and importance is described and analyzed.
文摘the paper discusses the advantage and disadvantage of organic chemistry teaching mode of multimedia auxiliary university compared with traditional teaching mode. And combined with the author＇ s teaching practice the paper sums up that the multimedia technology shall be used as the auxiliary method of traditional teaching to optimize classroom teaching, improve the classroom efficiency and reflect the true value of the multimedia auxiliary teaching.
基金supported by the Key Project of National Natural Science Foundation of China(81130063)the 973 Project(2012CB 518503)
文摘Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.
