The design of a turbofan rotor speed control system, using model reference adaptive control(MRAC) method with input and output measurements, is discussed for the purpose of practical application. The nonlinear compe...The design of a turbofan rotor speed control system, using model reference adaptive control(MRAC) method with input and output measurements, is discussed for the purpose of practical application. The nonlinear compensator based on functional link neural network is used to deal with the engine nonlinearity and the hardware-in-loop simulation is also developed. The results show that the nonlinear MRAC controller has the adequate performance of compensating and adapting nonlinearity arising from the change of engine state or working environment. Such feature demonstrates potential practical applications of MRAC for aeroengine control system.展开更多
The trusted network connection is a hot spot in trusted computing field and the trust measurement and access control technology are used to deal with network security threats in trusted network.But the trusted network...The trusted network connection is a hot spot in trusted computing field and the trust measurement and access control technology are used to deal with network security threats in trusted network.But the trusted network connection lacks fine-grained states and real-time measurement support for the client and the authentication mechanism is difficult to apply in the trusted network connection,it is easy to cause the loss of identity privacy.In order to solve the abovedescribed problems,this paper presents a trust measurement scheme suitable for clients in the trusted network,the scheme integrates the following attributes such as authentication mechanism,state measurement,and real-time state measurement and so on,and based on the authentication mechanism and the initial state measurement,the scheme uses the realtime state measurement as the core method to complete the trust measurement for the client.This scheme presented in this paper supports both static and dynamic measurements.Overall,the characteristics of this scheme such as fine granularity,dynamic,real-time state measurement make it possible to make more fine-grained security policy and therefore it overcomes inadequacies existing in the current trusted network connection.展开更多
AIM: To compare the ligase detection reaction (LDR) and real-time PCR for detection of low abundant YMDD mutants in patients with chronic hepatitis B infection.METHODS: Mixtures of plasmids and serum samples from 52 c...AIM: To compare the ligase detection reaction (LDR) and real-time PCR for detection of low abundant YMDD mutants in patients with chronic hepatitis B infection.METHODS: Mixtures of plasmids and serum samples from 52 chronic hepatitis B patients with low abundant lamivudine-resistant mutations were tested with LDR and real-time PCR. Time required and reagent cost for both assays were evaluated.RESULTS: Real-time PCR detected 100, 50, 10, 1 and 0.1% of YIDD plasmid, whereas LDR detected 100, 50, 10, 1, 0.1, and 0.01% of YIDD plasmid, in mixtures with YMDD plasmid of 106 copies/mL. Among the 52 clinical serum samples, completely concordant results were obtained for all samples by both assays, and 39 YIDD, 9 YVDD, and 4 YIDD/YVDD were detected. Cost and time required for LDR and real-time PCR are 60/80 CNY (8/10.7 US dollars) and 4.5/2.5 h, respectively.CONCLUSION: LDR and real-time PCR are both sensitive and inexpensive methods for monitoring low abundant YMDD mutants during lamivudine therapy in patients with chronic hepatitis B. LDR is more sensitive and less expensive, while real-time PCR is more rapid.展开更多
This study is concerned with the feasibility of power generation using a pico-hydraulic turbine from sewage flowing in pipes. First, the sewage flow rate at two connection points to the Toyogawa River-Basin Sewerage, ...This study is concerned with the feasibility of power generation using a pico-hydraulic turbine from sewage flowing in pipes. First, the sewage flow rate at two connection points to the Toyogawa River-Basin Sewerage, Japan, was explored for over a year to elucidate the hydraulic energy potential of the sewage. Second, the performance of the pico-hydraulic turbine was investigated via laboratory experiments that supposed the turbine to be installed in the sewage pipe at the connection points. This study indicates that the connection points have hydraulic potential that can be used for power generation throughout the year. It also demonstrates that the pico-hydraulic turbine can be usefully employed for power generation from sewage flowing in the pipe at the connection points.展开更多
Based on concave function, the problem of finding the sparse solution of absolute value equations is relaxed to a concave programming, and its corresponding algorithm is proposed, whose main part is solving a series o...Based on concave function, the problem of finding the sparse solution of absolute value equations is relaxed to a concave programming, and its corresponding algorithm is proposed, whose main part is solving a series of linear programming. It is proved that a sparse solution can be found under the assumption that the connected matrixes have range space property(RSP). Numerical experiments are also conducted to verify the efficiency of the proposed algorithm.展开更多
Combined with practical engineering, based on the introduction of soil arching theory, we explore the impact of barrier piles in blind sheet-pile bank connecting structure. Besides, we build a plane strain model by AB...Combined with practical engineering, based on the introduction of soil arching theory, we explore the impact of barrier piles in blind sheet-pile bank connecting structure. Besides, we build a plane strain model by ABAQUS sot'cware to study the impact of cross section type, the pile spacing and soil properties on soil arching effect. We find that cross section type of the pile has a certain influence on soil stress distribution in front of the barrier piles by comparing circular cross section and rectangular cross section. We also find that clear distance between the barrier piles and cohesive force of the soil have a great influence on that impact. We can increase clear distance between the barrier piles appropriately to improve the efficiency of construction and reduce the proiect cost.展开更多
AIM:To investigate the effect of emodin on pancreatic claudin-5 and occludin expression,and pancreatic paracellular permeability in acute pancreatitis(AP).METHODS:Experimental pancreatitis was induced by retrograde in...AIM:To investigate the effect of emodin on pancreatic claudin-5 and occludin expression,and pancreatic paracellular permeability in acute pancreatitis(AP).METHODS:Experimental pancreatitis was induced by retrograde injection of 5% sodium taurocholate into the biliopancreatic duct.Emodin was injected via the external jugular vein 0 or 6 h after induction of AP.Rats from sham operation and AP groups were injected with normal saline at the same time.Samples of pancreas were obtained 6 or 12 h after drug administration.Pancreatic morphology was examined with hematoxylin and eosin staining.Pancreatic edema was estimated by measuring tissue water content.Tumor necrosis factor(TNF)-α and interleukin(IL)-6 level were measured by enzyme-linked immunosorbent assay.Pancreatic paracellular permeability was assessed by tissue dye extravasation.Expression of pancreatic claudin-5 and occludin was examined by immunohistology,quantitative real-time reverse transcriptase polymerase chain reaction and western blotting.RESULTS:Pancreatic TNF-α and IL-6 levels,wet/dry ratio,dye extravasation,and histological score were significantly elevated at 3,6 and 12 h following sodium taurocholate infusion;treatment with emodin prevented these changes at all time points.Immunostaining of claudin-5 and occludin was detected in rat pancreas,which was distributed in pancreatic acinar cells,ductal cells and vascular endothelial cells,respectively.Sodium taurocholate infusion significantly decreased pancreatic claudin-5 and occludin mRNA and protein levels at 3,6 and 12 h,and that could be promoted by intravenous administration of emodin at all time points.CONCLUSION:These results demonstrate that emodin could promote pancreatic claudin-5 and occludin expression,and reduce pancreatic paracellular permeability.展开更多
In this paper,an improved Susceptible-Infected-Susceptible(SIS) epidemic spreading model is proposed in order to provide a theoretical method to analyze and predict the spreading of diseases.This model is based on the...In this paper,an improved Susceptible-Infected-Susceptible(SIS) epidemic spreading model is proposed in order to provide a theoretical method to analyze and predict the spreading of diseases.This model is based on the following ideas:in social networks,the contact probability between nodes is decided by their social distances and their active degrees.The contact probability of two indirectly connected nodes is decided by the shortest path between them.Theoretical analysis and simulation experiment were conducted to evaluate the performance of this improved model.Because the proposed model is independent of the network structure,simulation experiments were done in several kinds of networks,namely the ER network,the random regular network,the WS small world network,and the BA scale-free network,in order to study the influences of certain factors have on the epidemic spreading,such as the social contact active degree,the network structure,the average degree,etc.This improved model provides an idea for studying the spreading rule of computer virus,attitudes,fashion styles and public opinions in social networks.展开更多
The beam-to-column semirigid connection in a steel frame structure is represented by a zero-length rotational spring at the end of the beam element. The beam-to-column semirigid connection behavior is represented by i...The beam-to-column semirigid connection in a steel frame structure is represented by a zero-length rotational spring at the end of the beam element. The beam-to-column semirigid connection behavior is represented by its moment-rotation relationship. Several traditional mathematical models have been proposed to fit the moment-rotation curves from the experimental database,but they may be more reliable within certain ranges. In this paper, the intellectualized analytical model is proposed in the semirigid connections for top and seat angles with double web angles using the feed-forward back-propagation artificial neural network (BP-ANN) technique. the intellectualized analytical model from experimental results based on BP-ANN is more reliable and it is a better choice to the moment-rotation curves for beam-to-column semirigid connection. The results are found to provide effectiveness to the experimental response that is satisfactory for use in steel structural engineering design.展开更多
This paper analyzes how the themes of magical realism and female divinity intersect in the novel The Puttermesser Papers (1997) by Cynthia Ozick. In the "Introduction", the writer defines magical realism and discu...This paper analyzes how the themes of magical realism and female divinity intersect in the novel The Puttermesser Papers (1997) by Cynthia Ozick. In the "Introduction", the writer defines magical realism and discusses its connections to Women's Studies. The next section, "The Bitter Butter Knife", discusses the protagonist's (Ruth Puttermesser) boring existence and pathetic attempts to connect to her Jewish ancestry. In "The Problematic Paradise", the author focuses on Puttermesser's attempts to take control of her life by creating the first female golem and the ups and downs of paradise. This author argues that the female protagonist of the novel utilizes magical realism as a tool of empowerment over personal oppression.展开更多
Tubular section members made of steel are common in space trusses. There are several types of connections to attach these members. The most popular is the staking end-flattened connection. The reduced cost and the fas...Tubular section members made of steel are common in space trusses. There are several types of connections to attach these members. The most popular is the staking end-flattened connection. The reduced cost and the fast assemblage of the truss are among the advantages of the staking end-flattened connection on 3D trusses. However, such connections present disadvantages like eccentricities and stiffness weakening of the tubular members. In this work, based on computer simulations and experimental lab tests on prototypes, small changes on the staking end-flattened connections such as reinforcement and eccentricity correction are evaluated. The results show an increase of 68% for local collapse and 17% for global collapse in the truss load carrying capacity when the suggested changes proposed in this article are used for the staking end-flattened connections.展开更多
Compression and encryption are widely used in network traffic in order to improve efficiency and security of some systems.We propose a scheme to concatenate both functions and run them in a paralle pipelined fashion,d...Compression and encryption are widely used in network traffic in order to improve efficiency and security of some systems.We propose a scheme to concatenate both functions and run them in a paralle pipelined fashion,demonstrating both a hardware and a software implementation.With minor modifications to the hardware accelerators,latency can be reduced to half.Furthermore,we also propose a seminal and more efficient scheme,where we integrate the technology of encryption into the compression algorithm.Our new integrated optimization scheme reaches an increase of 1.6X by using parallel software scheme However,the security level of our new scheme is not desirable compare with previous ones.Fortunately,we prove that this does not affect the application of our schemes.展开更多
The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimen...The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimensional engine simulation code.In a first part,a CFD analysis is made in order to show the importance of the density in the modeling approach.Then,the CFD code is used,as a numerical test bench,for the pressure losses models development.These coefficients depend on the geometrical characteristics of the junction and an experimental validation is made with the use of a shock tube test bench.All the models are then included in the engine simulation code of the laboratory.The numerical calculation of unsteady compressible flow,in each pipe of the inlet and exhaust systems,is made and the calculated engine torque is compared with experimental measurements.展开更多
A stationary clearance link algorithm(SCLA)for calculating the reaction-force of revolute clearance joints in crank slider mechanisms is proposed in this paper.The SCLA is more efficient than other algorithms of the s...A stationary clearance link algorithm(SCLA)for calculating the reaction-force of revolute clearance joints in crank slider mechanisms is proposed in this paper.The SCLA is more efficient than other algorithms of the same accuracy.Furthermore,based on the Winkler foundation model,an unsymmetrical Winkler foundation model and a double elastic layer Winkler model are proposed.By integrating a dynamic model and the unsymmetrical Winkler foundation model with Archard wear model,an improved integrated wear prediction model is also generated.A series of experiments have been performed to compare with the predicted analysis data,and the results showed a good agreement.As a real industry application,with the double elastic layer Winkler model,the integrated wear prediction model was successfully used to predict the wear depth of the joint bearing(bimetallic bearing)for the cantilever crane of a concrete pump truck of Sany Heavy Industry.展开更多
文摘The design of a turbofan rotor speed control system, using model reference adaptive control(MRAC) method with input and output measurements, is discussed for the purpose of practical application. The nonlinear compensator based on functional link neural network is used to deal with the engine nonlinearity and the hardware-in-loop simulation is also developed. The results show that the nonlinear MRAC controller has the adequate performance of compensating and adapting nonlinearity arising from the change of engine state or working environment. Such feature demonstrates potential practical applications of MRAC for aeroengine control system.
基金ACKNOWLEDGMENT This work was supported by the National Basic Research Program of China (973 Project) (NO.2007CB311100), the National Science Foundation for Young Scholars of China (Grant No.61001091), Beijing Nature Science Foundation(No. 4122012), "next-generation broadband wireless mobile communication network" National Science and Technology major Special issue funding(No. 2012ZX03002003), Funding Program for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality of China and the key technology research and validation issue for the emergency treatment telemedicine public service platform which integrates the military and civilian and bases on the broadband wireless networks(No.2013ZX03006001-005), the issue belongs to Major national science and technology projects.
文摘The trusted network connection is a hot spot in trusted computing field and the trust measurement and access control technology are used to deal with network security threats in trusted network.But the trusted network connection lacks fine-grained states and real-time measurement support for the client and the authentication mechanism is difficult to apply in the trusted network connection,it is easy to cause the loss of identity privacy.In order to solve the abovedescribed problems,this paper presents a trust measurement scheme suitable for clients in the trusted network,the scheme integrates the following attributes such as authentication mechanism,state measurement,and real-time state measurement and so on,and based on the authentication mechanism and the initial state measurement,the scheme uses the realtime state measurement as the core method to complete the trust measurement for the client.This scheme presented in this paper supports both static and dynamic measurements.Overall,the characteristics of this scheme such as fine granularity,dynamic,real-time state measurement make it possible to make more fine-grained security policy and therefore it overcomes inadequacies existing in the current trusted network connection.
文摘AIM: To compare the ligase detection reaction (LDR) and real-time PCR for detection of low abundant YMDD mutants in patients with chronic hepatitis B infection.METHODS: Mixtures of plasmids and serum samples from 52 chronic hepatitis B patients with low abundant lamivudine-resistant mutations were tested with LDR and real-time PCR. Time required and reagent cost for both assays were evaluated.RESULTS: Real-time PCR detected 100, 50, 10, 1 and 0.1% of YIDD plasmid, whereas LDR detected 100, 50, 10, 1, 0.1, and 0.01% of YIDD plasmid, in mixtures with YMDD plasmid of 106 copies/mL. Among the 52 clinical serum samples, completely concordant results were obtained for all samples by both assays, and 39 YIDD, 9 YVDD, and 4 YIDD/YVDD were detected. Cost and time required for LDR and real-time PCR are 60/80 CNY (8/10.7 US dollars) and 4.5/2.5 h, respectively.CONCLUSION: LDR and real-time PCR are both sensitive and inexpensive methods for monitoring low abundant YMDD mutants during lamivudine therapy in patients with chronic hepatitis B. LDR is more sensitive and less expensive, while real-time PCR is more rapid.
文摘This study is concerned with the feasibility of power generation using a pico-hydraulic turbine from sewage flowing in pipes. First, the sewage flow rate at two connection points to the Toyogawa River-Basin Sewerage, Japan, was explored for over a year to elucidate the hydraulic energy potential of the sewage. Second, the performance of the pico-hydraulic turbine was investigated via laboratory experiments that supposed the turbine to be installed in the sewage pipe at the connection points. This study indicates that the connection points have hydraulic potential that can be used for power generation throughout the year. It also demonstrates that the pico-hydraulic turbine can be usefully employed for power generation from sewage flowing in the pipe at the connection points.
文摘Based on concave function, the problem of finding the sparse solution of absolute value equations is relaxed to a concave programming, and its corresponding algorithm is proposed, whose main part is solving a series of linear programming. It is proved that a sparse solution can be found under the assumption that the connected matrixes have range space property(RSP). Numerical experiments are also conducted to verify the efficiency of the proposed algorithm.
文摘Combined with practical engineering, based on the introduction of soil arching theory, we explore the impact of barrier piles in blind sheet-pile bank connecting structure. Besides, we build a plane strain model by ABAQUS sot'cware to study the impact of cross section type, the pile spacing and soil properties on soil arching effect. We find that cross section type of the pile has a certain influence on soil stress distribution in front of the barrier piles by comparing circular cross section and rectangular cross section. We also find that clear distance between the barrier piles and cohesive force of the soil have a great influence on that impact. We can increase clear distance between the barrier piles appropriately to improve the efficiency of construction and reduce the proiect cost.
基金Supported by National Natural Science Foundation of China,No.30500688
文摘AIM:To investigate the effect of emodin on pancreatic claudin-5 and occludin expression,and pancreatic paracellular permeability in acute pancreatitis(AP).METHODS:Experimental pancreatitis was induced by retrograde injection of 5% sodium taurocholate into the biliopancreatic duct.Emodin was injected via the external jugular vein 0 or 6 h after induction of AP.Rats from sham operation and AP groups were injected with normal saline at the same time.Samples of pancreas were obtained 6 or 12 h after drug administration.Pancreatic morphology was examined with hematoxylin and eosin staining.Pancreatic edema was estimated by measuring tissue water content.Tumor necrosis factor(TNF)-α and interleukin(IL)-6 level were measured by enzyme-linked immunosorbent assay.Pancreatic paracellular permeability was assessed by tissue dye extravasation.Expression of pancreatic claudin-5 and occludin was examined by immunohistology,quantitative real-time reverse transcriptase polymerase chain reaction and western blotting.RESULTS:Pancreatic TNF-α and IL-6 levels,wet/dry ratio,dye extravasation,and histological score were significantly elevated at 3,6 and 12 h following sodium taurocholate infusion;treatment with emodin prevented these changes at all time points.Immunostaining of claudin-5 and occludin was detected in rat pancreas,which was distributed in pancreatic acinar cells,ductal cells and vascular endothelial cells,respectively.Sodium taurocholate infusion significantly decreased pancreatic claudin-5 and occludin mRNA and protein levels at 3,6 and 12 h,and that could be promoted by intravenous administration of emodin at all time points.CONCLUSION:These results demonstrate that emodin could promote pancreatic claudin-5 and occludin expression,and reduce pancreatic paracellular permeability.
基金supported by National Natural Science Foundation of China 61301091Shaanxi Province Science and Technology Project 2015GY015
文摘In this paper,an improved Susceptible-Infected-Susceptible(SIS) epidemic spreading model is proposed in order to provide a theoretical method to analyze and predict the spreading of diseases.This model is based on the following ideas:in social networks,the contact probability between nodes is decided by their social distances and their active degrees.The contact probability of two indirectly connected nodes is decided by the shortest path between them.Theoretical analysis and simulation experiment were conducted to evaluate the performance of this improved model.Because the proposed model is independent of the network structure,simulation experiments were done in several kinds of networks,namely the ER network,the random regular network,the WS small world network,and the BA scale-free network,in order to study the influences of certain factors have on the epidemic spreading,such as the social contact active degree,the network structure,the average degree,etc.This improved model provides an idea for studying the spreading rule of computer virus,attitudes,fashion styles and public opinions in social networks.
文摘The beam-to-column semirigid connection in a steel frame structure is represented by a zero-length rotational spring at the end of the beam element. The beam-to-column semirigid connection behavior is represented by its moment-rotation relationship. Several traditional mathematical models have been proposed to fit the moment-rotation curves from the experimental database,but they may be more reliable within certain ranges. In this paper, the intellectualized analytical model is proposed in the semirigid connections for top and seat angles with double web angles using the feed-forward back-propagation artificial neural network (BP-ANN) technique. the intellectualized analytical model from experimental results based on BP-ANN is more reliable and it is a better choice to the moment-rotation curves for beam-to-column semirigid connection. The results are found to provide effectiveness to the experimental response that is satisfactory for use in steel structural engineering design.
文摘This paper analyzes how the themes of magical realism and female divinity intersect in the novel The Puttermesser Papers (1997) by Cynthia Ozick. In the "Introduction", the writer defines magical realism and discusses its connections to Women's Studies. The next section, "The Bitter Butter Knife", discusses the protagonist's (Ruth Puttermesser) boring existence and pathetic attempts to connect to her Jewish ancestry. In "The Problematic Paradise", the author focuses on Puttermesser's attempts to take control of her life by creating the first female golem and the ups and downs of paradise. This author argues that the female protagonist of the novel utilizes magical realism as a tool of empowerment over personal oppression.
文摘Tubular section members made of steel are common in space trusses. There are several types of connections to attach these members. The most popular is the staking end-flattened connection. The reduced cost and the fast assemblage of the truss are among the advantages of the staking end-flattened connection on 3D trusses. However, such connections present disadvantages like eccentricities and stiffness weakening of the tubular members. In this work, based on computer simulations and experimental lab tests on prototypes, small changes on the staking end-flattened connections such as reinforcement and eccentricity correction are evaluated. The results show an increase of 68% for local collapse and 17% for global collapse in the truss load carrying capacity when the suggested changes proposed in this article are used for the staking end-flattened connections.
基金partially supported by National Natural Science Foundation of China(No. 61202475,61572294,61502218)Outstanding Young Scientists Foundation Grant of Shandong Province(No.BS2014DX016)+3 种基金Nature Science Foundation of Shandong Province (No.ZR2012FQ029)Ph.D.Programs Foundation of Ludong University(No.LY2015033)Fujian Provincial Key Laboratory of Network Security and Cryptology Research Fund(Fujian Normal University)(No.15004)the Priority Academic Program Development of Jiangsu Higer Education Institutions,Jiangsu Collaborative Innovation Center on Atmospheric Environment and Equipment Technology
文摘Compression and encryption are widely used in network traffic in order to improve efficiency and security of some systems.We propose a scheme to concatenate both functions and run them in a paralle pipelined fashion,demonstrating both a hardware and a software implementation.With minor modifications to the hardware accelerators,latency can be reduced to half.Furthermore,we also propose a seminal and more efficient scheme,where we integrate the technology of encryption into the compression algorithm.Our new integrated optimization scheme reaches an increase of 1.6X by using parallel software scheme However,the security level of our new scheme is not desirable compare with previous ones.Fortunately,we prove that this does not affect the application of our schemes.
文摘The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimensional engine simulation code.In a first part,a CFD analysis is made in order to show the importance of the density in the modeling approach.Then,the CFD code is used,as a numerical test bench,for the pressure losses models development.These coefficients depend on the geometrical characteristics of the junction and an experimental validation is made with the use of a shock tube test bench.All the models are then included in the engine simulation code of the laboratory.The numerical calculation of unsteady compressible flow,in each pipe of the inlet and exhaust systems,is made and the calculated engine torque is compared with experimental measurements.
基金supported by the National Natural Science Foundation of China(Grant No.51175409)
文摘A stationary clearance link algorithm(SCLA)for calculating the reaction-force of revolute clearance joints in crank slider mechanisms is proposed in this paper.The SCLA is more efficient than other algorithms of the same accuracy.Furthermore,based on the Winkler foundation model,an unsymmetrical Winkler foundation model and a double elastic layer Winkler model are proposed.By integrating a dynamic model and the unsymmetrical Winkler foundation model with Archard wear model,an improved integrated wear prediction model is also generated.A series of experiments have been performed to compare with the predicted analysis data,and the results showed a good agreement.As a real industry application,with the double elastic layer Winkler model,the integrated wear prediction model was successfully used to predict the wear depth of the joint bearing(bimetallic bearing)for the cantilever crane of a concrete pump truck of Sany Heavy Industry.