目的运用螺旋CT扫描测定肝脏体积评估乙型肝炎肝硬化患者肝脏储备功能。方法2016年6月~2020年2月我院诊治的乙型肝炎肝硬化患者60例,行CT增强扫描,应用法国Intrasense公司的Myrian XP Liver医学图像分析软件计算实际肝脏体积(PLV),并与...目的运用螺旋CT扫描测定肝脏体积评估乙型肝炎肝硬化患者肝脏储备功能。方法2016年6月~2020年2月我院诊治的乙型肝炎肝硬化患者60例,行CT增强扫描,应用法国Intrasense公司的Myrian XP Liver医学图像分析软件计算实际肝脏体积(PLV),并与理论肝脏体积(TLV)比较。根据肝脏CT表现,将肝硬化分为1~4级。结果本组肝硬化CT分级为1级12例,2级25,3级13例和4级10例;CT 1级患者PLV为(996.2±145.5)cm^3,显著小于TLV【(1440.2±106.2)cm^3,P<0.05】,2级患者PLV为(918.2±116.4)cm^3,显著小于TLV【(1408.8±92.0)cm^3,P<0.05】,3级患者PLV为(852.4±70.8)cm^3,显著小于TLV【(1380.2±104.8)cm^3,P<0.05】,4级患者PLV为(724.9±92.3)cm^3,也显著小于TLV【(1352.1±88.2)cm^3,P<0.05】;15例Child-Pugh A级患者PLV为(985.2±250.8)cm^3,显著小于TLV【(1420.6±125.0)cm^3,P<0.05】,31例B级患者PLV为(820.6±105.4)cm^3,显著小于TLV【(1381.8±110.8)cm^3,P<0.05】,14例C级患者PLV为(704.6±70.5)cm^3,显著小于TLV【(1340.5±120.9)cm^3,P<0.05】;14例MELD评分<10分患者PLV为(960.6±162.5)cm^3,显著小于TLV【(1408.2±92.8)cm^3,P<0.05】,28例MELD评分为10~20分患者PLV为(842.6±90.6)cm^3,显著小于TLV【(1372.4±108.0)cm^3,P<0.05】,18例MELD评分>20分患者PLV为(782.1±40.8)cm^3,显著小于TLV【(1325.0±130.8)cm^3,P<0.05】。结论应用分析软件测定螺旋CT扫描获得的实际肝脏体积能够有效评价乙型肝炎肝硬化患者肝硬化程度及其储备功能,值得临床总结应用。展开更多
Background and Study Aims: The Olympus EU-IP2 threedimensional endoscopic ultrasound (3D-EUS) imaging system makes it possible to display tumors in three dimensions and estimate their volume. Materials and Methods: Ex...Background and Study Aims: The Olympus EU-IP2 threedimensional endoscopic ultrasound (3D-EUS) imaging system makes it possible to display tumors in three dimensions and estimate their volume. Materials and Methods: Experimental and clinical studies of the volume estimation function of the Olympus EU-IP2 system was carried out to evaluate its accuracy and assess the extent of tumor shrinkage caused by fixation, dehydration, and staining. Results. In the experimental studies, compared with the actual volume of a 1000-mm3 gelatin column, the estimated volume was found to be equivalent to 114 ±1.8% with the 3R probe and 143 ±0.8 % with the 2R probe (mean plus or minus standard deviation). The mean estimated volume of tumor models was 127 ±8.5%with the 3R probe and 131 ±6.8% with the 2R probe. Greater distance from the probe was associated with a greater degree of error than the target object’s size, angle, or the number of traces of its outline made. In the clinical studies, compared with the histologically determined tumor volume (100%), the mean estimated tumor volume was 178 ±48.2%in situ, 168 ±31.3%in resected specimens, and 137 ±31.5%after fixation. Fixation, dehydration, and staining were thus associated with tumor shrinkage. Conclusions: The volume of gastrointestinal lesions can be estimated by 3D-EUS, although it is overestimated in comparison with actual values. 3D-EUS also allows direct comparisons to be made between the tumor volume before surgery and the volume of fixed pathological specimens, so that the rate of tumor shrinkage can be estimated.展开更多
文摘目的运用螺旋CT扫描测定肝脏体积评估乙型肝炎肝硬化患者肝脏储备功能。方法2016年6月~2020年2月我院诊治的乙型肝炎肝硬化患者60例,行CT增强扫描,应用法国Intrasense公司的Myrian XP Liver医学图像分析软件计算实际肝脏体积(PLV),并与理论肝脏体积(TLV)比较。根据肝脏CT表现,将肝硬化分为1~4级。结果本组肝硬化CT分级为1级12例,2级25,3级13例和4级10例;CT 1级患者PLV为(996.2±145.5)cm^3,显著小于TLV【(1440.2±106.2)cm^3,P<0.05】,2级患者PLV为(918.2±116.4)cm^3,显著小于TLV【(1408.8±92.0)cm^3,P<0.05】,3级患者PLV为(852.4±70.8)cm^3,显著小于TLV【(1380.2±104.8)cm^3,P<0.05】,4级患者PLV为(724.9±92.3)cm^3,也显著小于TLV【(1352.1±88.2)cm^3,P<0.05】;15例Child-Pugh A级患者PLV为(985.2±250.8)cm^3,显著小于TLV【(1420.6±125.0)cm^3,P<0.05】,31例B级患者PLV为(820.6±105.4)cm^3,显著小于TLV【(1381.8±110.8)cm^3,P<0.05】,14例C级患者PLV为(704.6±70.5)cm^3,显著小于TLV【(1340.5±120.9)cm^3,P<0.05】;14例MELD评分<10分患者PLV为(960.6±162.5)cm^3,显著小于TLV【(1408.2±92.8)cm^3,P<0.05】,28例MELD评分为10~20分患者PLV为(842.6±90.6)cm^3,显著小于TLV【(1372.4±108.0)cm^3,P<0.05】,18例MELD评分>20分患者PLV为(782.1±40.8)cm^3,显著小于TLV【(1325.0±130.8)cm^3,P<0.05】。结论应用分析软件测定螺旋CT扫描获得的实际肝脏体积能够有效评价乙型肝炎肝硬化患者肝硬化程度及其储备功能,值得临床总结应用。
文摘Background and Study Aims: The Olympus EU-IP2 threedimensional endoscopic ultrasound (3D-EUS) imaging system makes it possible to display tumors in three dimensions and estimate their volume. Materials and Methods: Experimental and clinical studies of the volume estimation function of the Olympus EU-IP2 system was carried out to evaluate its accuracy and assess the extent of tumor shrinkage caused by fixation, dehydration, and staining. Results. In the experimental studies, compared with the actual volume of a 1000-mm3 gelatin column, the estimated volume was found to be equivalent to 114 ±1.8% with the 3R probe and 143 ±0.8 % with the 2R probe (mean plus or minus standard deviation). The mean estimated volume of tumor models was 127 ±8.5%with the 3R probe and 131 ±6.8% with the 2R probe. Greater distance from the probe was associated with a greater degree of error than the target object’s size, angle, or the number of traces of its outline made. In the clinical studies, compared with the histologically determined tumor volume (100%), the mean estimated tumor volume was 178 ±48.2%in situ, 168 ±31.3%in resected specimens, and 137 ±31.5%after fixation. Fixation, dehydration, and staining were thus associated with tumor shrinkage. Conclusions: The volume of gastrointestinal lesions can be estimated by 3D-EUS, although it is overestimated in comparison with actual values. 3D-EUS also allows direct comparisons to be made between the tumor volume before surgery and the volume of fixed pathological specimens, so that the rate of tumor shrinkage can be estimated.
