In this paper, bulk flotation followed by separation was investigated to concentrate purified molybdenite product from Jinduicheng molybdenum ores(Shanxi province, China). The bench scale tests mainly focussed on sepa...In this paper, bulk flotation followed by separation was investigated to concentrate purified molybdenite product from Jinduicheng molybdenum ores(Shanxi province, China). The bench scale tests mainly focussed on separation of molybdenite from other sulfide minerals using the new type of depressants.The effect of each single depressant, including organic depressant-modified dextrin(MD), P-Nokes reagent(PN) and sodium trithiocarbonate(ST), and their mixtures on galena, chalcopyrite and other sulfide ores, was examined in turn by changing the concentrations used in cleaner flotation tests. Closed circuit experiments were carried out under the optimal condition and satisfying recovery and grade of molybdenite concentrate could be achieved(86.294% and 53.157%, respectively). A potential reagent regime was developed, with more environmental friendly and more economical advantages due to the introduction of modified dextrin.展开更多
Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tre...Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tremendous effort from both academia and industry, two serine protease inhibitors telaprevir and boceprevir for treating chronic hepatitis C have finally reached the clinic. Although these compounds are only approved for combination use with interferon and ribavirin in genotype 1 HCV infected chronic patients, the management of HCV patients however is now evolving incredibly. Here, we overviewed a series of landmark studies, regarding the clinical development of telaprevir and boceprevir. We discussed the mechanism-of-action of telaprevir/boceprevir and their potential application in HCV-positive liver transplantation patients. We further emphasized some emerging concerns with perspective of further development in this field.展开更多
Thyrotoxicosis may present in many ways;severe vomiting as a prominent symptom of thyrotoxicosis is uncommon.In this paper,we report a 24-year-old Chinese male with hyperthyroidism who presented with recurrent severe ...Thyrotoxicosis may present in many ways;severe vomiting as a prominent symptom of thyrotoxicosis is uncommon.In this paper,we report a 24-year-old Chinese male with hyperthyroidism who presented with recurrent severe vomiting.The patient had had intermittent vomiting for seven years and had lost approximately 15 kg of weight.Gastroscopic examinations revealed chronic gastritis and one occasion peptic ulcer.He was treated with antacid and proton pump inhibitors,but his symptoms had no relief.His presenting symptoms suggested hyperthyroidism and were confirmed by laboratory data.After a month of propylthiouracil therapy,his symptoms were relieved.It should be noted that hyperthyroidism patients can have unexplained vomiting,and that hyperthyroidism may coexist with peptic ulcer in rare cases.Awareness of such atypical presentations of hyperthyroidism may help to make a correct diagnosis.展开更多
基金funding from the Innovation Driven Plan of Central South University (No.2016zzts109)the financial support from Jinduicheng Molybdenum Group Co.Ltd.(JDCMMC)
文摘In this paper, bulk flotation followed by separation was investigated to concentrate purified molybdenite product from Jinduicheng molybdenum ores(Shanxi province, China). The bench scale tests mainly focussed on separation of molybdenite from other sulfide minerals using the new type of depressants.The effect of each single depressant, including organic depressant-modified dextrin(MD), P-Nokes reagent(PN) and sodium trithiocarbonate(ST), and their mixtures on galena, chalcopyrite and other sulfide ores, was examined in turn by changing the concentrations used in cleaner flotation tests. Closed circuit experiments were carried out under the optimal condition and satisfying recovery and grade of molybdenite concentrate could be achieved(86.294% and 53.157%, respectively). A potential reagent regime was developed, with more environmental friendly and more economical advantages due to the introduction of modified dextrin.
基金Supported by Foundation for Liver and Gastrointestinal Research (SLO)The Netherlands Organisation for Scientific Research (NWO), No. VENI-grant 916-13-032 (to Pan Q)
文摘Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tremendous effort from both academia and industry, two serine protease inhibitors telaprevir and boceprevir for treating chronic hepatitis C have finally reached the clinic. Although these compounds are only approved for combination use with interferon and ribavirin in genotype 1 HCV infected chronic patients, the management of HCV patients however is now evolving incredibly. Here, we overviewed a series of landmark studies, regarding the clinical development of telaprevir and boceprevir. We discussed the mechanism-of-action of telaprevir/boceprevir and their potential application in HCV-positive liver transplantation patients. We further emphasized some emerging concerns with perspective of further development in this field.
文摘Thyrotoxicosis may present in many ways;severe vomiting as a prominent symptom of thyrotoxicosis is uncommon.In this paper,we report a 24-year-old Chinese male with hyperthyroidism who presented with recurrent severe vomiting.The patient had had intermittent vomiting for seven years and had lost approximately 15 kg of weight.Gastroscopic examinations revealed chronic gastritis and one occasion peptic ulcer.He was treated with antacid and proton pump inhibitors,but his symptoms had no relief.His presenting symptoms suggested hyperthyroidism and were confirmed by laboratory data.After a month of propylthiouracil therapy,his symptoms were relieved.It should be noted that hyperthyroidism patients can have unexplained vomiting,and that hyperthyroidism may coexist with peptic ulcer in rare cases.Awareness of such atypical presentations of hyperthyroidism may help to make a correct diagnosis.
