宫间武论日本性教育的现代化课题

宫间武是日本著名的性教育专家。最近,他在日本《教育心理》杂志著文论及日本性教育的现代化课题。他认为在日本性教育的理论研究和实践获得一定成果的时候,还存在着两个问题是急需解决的。

漫话“白宫同事计划”

在美国联邦政府各部门活跃着一批精力充沛的年轻人。他们并不在政府工作人员的正式编制内,但工作起来并不逊色于正式雇员.不时还有一些专家给他们上课。“白宫同事计划”为这些青年提供了在政府工作和学习的机会。

阿拉伯文化简讯

据埃及《消息报》报道,阿拉伯著名大作家纳吉布·马哈福兹的名作《宫间街》、《思宫街》、《甘露街》三部曲已被译成波斯文.在德黑兰举办的1992年国际书展上展出了《三部曲》的波斯文译本.这是埃及长篇小说首次译成波斯文出版.

Experience of endometrial stromal sarcoma with fertility conservation treatment

The paper introduced the experience of a case of recurrence of endometrial stromal sarcoma with fertility conservation treatment after full-term delivery. A 24-year-old unmarried patient who, with her increasing amount of menstruation in the late six months, had a mass in her lower-abdominal which was confirmed by B-ultrasonic diagnosis as myometrium mixed mass, was given an enucleation of uterus tumor. The pathological examination of tumor sample revealed it as lowgrade endometrial stromal sarcoma (LESS). And the patient underwent 6 cycles of chemotherapy over 8 months before she got pregnant and had a full-term delivery. But in 34 months after delivery, the disease recurred with metastatic of pelvic and peritoneal cavity and the patient had to receive comprehensive therapy. Conclusion: The unmarried young patient with stage I low-grade endometrial stromal sarcoma has the chance to preserve uterus for her pregnancy and delivery. But the using of cesarean needs do staging operation and prognosis evaluation.

Influences of different time intervals between loop electrosurgical excision and abdominal hysterectomy or radical hysterectomy on postoperative complications: a retrospective analysis

Objective： To study the influences of different time intervals between loop electrosurgical excision （LEEP） and abdominal hysterectomy or radical hysterectomy on postoperative complications. Methods： Sixty-eight patients, who received subsequent abdominal hysterectomy or radical hysterectomy after LEEP due to C1N III and cervical cancer （IA1, IA2 and IB1）, were included in the present study. The hospital and clinic records of these patients were reviewed. The patients were divided into three groups according to the time intervals between LEEP and hysterectomy or radical hysterectomy： group l（within 48 h）, group 2 （between 48 h to 6 weeks）, and group 3（〉 6 weeks ）.Results： General characteristics of patients, including the mean age, delivery history, BMI, menopausal status, clinical stage and HPV infection, were comparable between patients of different groups. There were no significant differences in the mean transfusion amount, posthysterectomy hospital stay or operation time between different groups. The frequencies and spectrum of complications were not significantly affected by the time interval between LEEP and hysterectomy or radical hysterectomy. Conclusion： It is concluded that whenever the LEEP is done, the operation including hysterectomy or radical hysterectomy can be conducted at any time as it is necessary for the patients.

Comparison of the Spatial Design Idea between Geunjeongjeon of Seoul and Chongzheng Hall in Shenyang imperial palace

The construction of the palace carries with it the importance of a country＇s political power. It shows the highest degree of a country＇s culture and represents the significant of planning artistic style.The modes of landscape plan of both Geunjeongjeon of Seoul Gyeongbokgung,and Chongzheng Hall in Shenyang imperial palace is characterized with the unique national culture under its own construction background. This article is to find out the feature of the spatial construction and the deepen artistic by analyzing the Plan technique structure modelling design and eyesight design for sDatial of the two palaces.

The Labors of the Months and the Zodiac Signs in the Cathedral of Otranto： An Iconographical Interpretation of the Symbols of Labor and Time

In 1163, Archbishop Gionata, Abbot of the Monastery of San Nicola of Casole in Puglia （Apulia）, commissioned Pantaleone, a learned monk and artist from the monastery, to decorate the pavement of the cathedral of Otranto with mosaics. This Italian Romanesque cathedral was dedicated to Santa Maria Annunziata or Saint Mary of The Annunciation. In the interior, the floor design in the shape of a tree contains an elaborate biblical program. The encyclopedic narrative of the mosaic symbolically unveils the meaning of the Tree of Life. The ieonography of the pavement＇s program combines biblical and pagan narratives evolving from a natural realm into a heavenly realm. The natural realm begins at the church＇s entrance with the symbolism of the earth-the roots of a tree-expanding through the nave and transept via the tree＇s trunk and its branches, culminating in the apse, at the end of the church, with the foliage oftbe top of the tree. This natural realm meets with the heavenly realm in two ways： at the crossing of the church or at the sacrificial altar, and at the apse of the church. Before reaching the altar or holy area, between the natural realm and the heavenly realm, the zodiac signs with the labors of the months are depicted.

Comprehensive Treatment and Prognostic Factors in Patients with Carcinoma of the Cervical Stump

OBJECTIVE To evaluate the applicability of combined therapyand the prognostic factors in patients with carcinoma of thecervical stump (CCS).METHODS The clinical records of 60 CCS patients whounderwent combined treatment in our hospital during a periodfrom January 2000 to December 2007, were collected andretrospectively analyzed. The prognostic factors were studiedusing univariate analysis. Analytical evaluation of the independentprognostic factors was performed using COX proportionalhazardsregression model.RESULTS The 1-, 3- and 5-year survival rates of the 60 patientswere 95%, 78% and 68%, respectively, with a median survivaltime of 32 months. Univariate survival analysis showed thatthese independent prognostic factors included positive pelviclymph nodes (P = 0.001), lymphovascular tumor embolus (P =0.001), and adjuvant chemotherapy (P = 0.011). In the 60 cases,postoperative local recurrence in the pelvic cavity occurred in1 and distant metastasis in 3. Related complications, such asradiocystitis, recto-vaginal fistula and vesico-vaginal fistula werefound in 6 of the total cases (10%). The serum levels of squamousepithelium antigen detected before and after treatment weresignificantly different (P = 0.000). The incidence of CCS is low;however, the disease is difficult to cure due to the high incidenceof complications and to the frequency of distant metastasis.Therefore, individualized treatment is needed. Complications fromsubtotal hysterectomy (STH) should be treated and controlledaggressively. Careful follow-up as well as close monitoring andobservation for significant symptoms in the postoperative coursewill enhance clinical outcome.CONCLUSION Cancer of the cervical stump has a lowmorbidity and severe complications, and most recurrences aredistant metastases. Because it is difficult to cure, there is a needto design a treatment regimen for each individual patient basedon the factors deemed as high risk. The surgical indications forsubtotal uterine resection should be followed and close follow-upafter surgery should be maintained.

Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells

The purpose of this study was to explore the change of telomerase in passage from human endometrial stromal stem cells isolated from human endometrium.Telomerase activity of cultured endometrial stromal cells was assessed at mRNA and protein levels using RT-PCR and immunohistochemistry technique.Telomerase mRNA and protein levels were higher at early passages,and then had a gradually decreased trend of immunoreactive intensity and gradually weakened positive cells with progressive passage in endometrial stromal stem cells.These results suggest that telomerase is contributed to the insenecence of endometrial stem cell.

Archaeological Work IN THE RUINS OF CHINGWA TAKTSE PALACES

The ruins of Chingwa Taktse are located in the Chogye Valley in Lhoka of Tibet.It faces the famous Valley of the Kings across a distance.According to Tibetan historical records,Chingwa Taktse was the earliest Tubo palace complex.Six notable palaces were built successively on the rolling hills here.Local folklore has it that it is a＂princess＇s tomb＂：

Malignant neoplasms of the uterus following radiation therapy for cervical carcinoma: a clinical study of 47 cases

Objective： To study the characteristics and clinical features of uterine neoplasms developed after radiation therapy for cervical carcinoma. Methods： Clinical data of 47 cases of uterine neoplasms occurred following radiation therapy for cervical carcinoma were retrospectively reviewed. Results： The median age at uterine neoplasms diagnosis was 62 years （range： 38-77 years）, and the median latency period from initial therapy to development of uterine neoplasms was 14 years （range： 5-35 years）. Thirty of 47 cases were endometrial carcinoma, of which 3 were uterine papillary serous carcinoma （UPSC）. Seventeen of 47 patients were uterine sarcoma, all of those were carcinosarcoma. The distribution by stage, grade, and histology of 30 cases of endometrial carcinoma was as follows： stage Ⅰb, 1 case; stage Ⅰc, 2 cases; stage Ⅱ, 6; stage Ⅲa, 4; stage Ⅲb, 2; stage Ⅲc, 11; stage Ⅳ, 4 cases; grade 1, two cases; grade 2, nine; grade 3 （include 3 UPSC patients）, seventeen; unknown grade, two; endometriod, 27; UPSC, 3 cases; 7 of 30 cases of endometrial carcinoma had recurrences （23.3%）, at median time to recurrence was 24 months, and their median survival time was 26 months. The overall 3- and 5-year survival rates were 60% and 38%, respectively. Of the 17 cases of uterine sarcoma, the median survival was 10 months, 6 patients occurred recurrence （35.9%）, at a median time to recurrence was 9 months, and their median survival was 6 months. The overall 3- and 5-year survival rates were 12% and 0, respectively. Conclusion： The main uterine neoplasms development after radiation therapy for cervical carcinoma is endometrial carcinomas, of which there is a preponderance of high-risk histological subtypes and a poor prognosis. Most of the uterine sarcomas occurred following radiation therapy for cervical carcinoma are carcinosarcomas and the prognosis is very poor.

Effects of immune activation on the retrieval of spatial memory

Objective It has been shown that there are extensive interactions between the central nervous system and the immune system.The present study focused on the effects of lipopolysaccharide（LPS）on memory retrieval,to explore the interaction between immune activation and memory.Methods C57BL/6J mice（8 weeks old）were first trained in the Morris water maze to reach asymptotic performance.Then mice were tested 24 h after the last training session and LPS was administered（1.25 mg/kg,i.p.）4 h prior to the testing.The retrieval of spatial memory was tested by probe trial,and the time spent in the target quadrant and the number of platform location crosses were recorded.ELISA was performed to detect interleukin-1β（IL-1β）protein level in the hippocampus of mice tested in the water maze.Results Although LPS induced overt sickness behavior and a significant increase in the level of IL-1β in the hippocampus of mice,there was no significant difference in the time spent in the target quadrant or in the number of platform location crosses between LPS-treated and control groups in the probe trial testing.Conclusion Immune activation induced by LPS does not impair the retrieval of spatial memory.

Clinical efficacy observation on treatment of primary dysmenorrhea with ginger-partitioned moxibustion at Zigong(EX-CA 1)

Objective： To investigate the clinical effect of ginger-partitioned moxibustion at Zigong（EX-CA 1） for primary dysmenorrhea. Methods： A total of 112 patients with primary dysmenorrhea were randomized into an observation group and a control group according to their visiting sequence, 56 cases in each group. Patients in the observation group received ginger-partitioned moxibustion at Zigong（EX-CA 1）, while patients in the control group received oral intake of analgesic. For both groups, treatment started 1 week before menstruation and lasted for 3 menstrual cycles, continued by a 3-month follow-up visit, then the clinical efficacy was evaluated. Results： By the end of treatment, symptom score in the observation group was lower than that in the control group, showing a statistical significance（P〈0.05）. After 3 months of treatment, the value of prostaglandin F2 a（PGF2α）, systolic-to-diastolic peak velocity ratio（S/D）, resistance index（RI） and pulsatility index（PI） in the observation group were significantly higher than those in the control group, showing statistical significances（all P〈0.01）.The recovery rate in the observation group was higher than that in the control group, showing a statistical significance（P〈0.05）. Conclusion： Ginger-partitioned moxibustion at Zigong（EX-CA 1） for primary dysmenorrhea is a combination of the merits of warming function of moxibustion, dissipating function of ginger and stimulation of acupoint, and is better than oral intake of analgesic.

Aqueous extract of lavender(Lavandula angustifolia) improves the spatial performance of a rat model of Alzheimer's disease

Objective Alzheimer＇s disease（AD） is one of the most important neurodegenerative disorders.It is characterized by dementia including def icits in learning and memory.The present study aimed to evaluate the effects of aqueous extract of lavender（Lavandula angustifolia） on spatial performance of AD rats.Methods Male Wistar rats were f irst divided into control and AD groups.Rat model of AD was established by intracerebroventricular injection of 10 ？g A？1-42 20 d prior to administration of the lavender extract.Rats in both groups were then introduced to 2 stages of task learning（with an interval of 20 d） in Morris water maze,each followed by one probe test.After the f irst stage of spatial learning,control and AD animals received different doses（50,100 and 200 mg/kg） of the lavender extract.Results In the first stage of experiment,the latency to locate the hidden platform in AD group was significantly higher than that in control group.However,in the second stage of experiment,control and AD rats that received distilled water（vehicle） showed similar performance,indicating that the maze navigation itself could improve the spatial learning of AD animals.Besides,in the second stage of experiment,control and AD rats that received lavender extract administration at different doses（50,100,and 200 mg/kg） spent less time locating the platform（except for the AD rats with 50 mg/kg extract treatment）,as compared with their counterparts with vehicle treatment,respectively.In addition,lavender extract significantly improved the performance of control and AD rats in the probe test,only at the dose of 200 mg/kg,as compared with their counterparts with vehicle treatment.Conclusion The lavender extract can effectively reverse spatial learning def icits in AD rats.