The paper presents abandonment, loneliness, and desolation, which defaced wifehood institution in South African polity. The disruption of family life and lack of opportunity for personal development turned women desol...The paper presents abandonment, loneliness, and desolation, which defaced wifehood institution in South African polity. The disruption of family life and lack of opportunity for personal development turned women desolate and children delinquent. The problem is the non-liberal practices in South Africa in spite of the struggle of people like Alan Paton. The objective of this paper is to study the South African society as presented by Alan Paton in line with his Liberalist Theory in order to make freedom and development achievable. The main factual points are that racism still exists; most black homes are separated; most black women are not empowered; colour segregation hinder development. The methodology adopted is the interpretation discourse of Alan Paton's Cry My Beloved Country in line with South African society. The Silent Separatist Policy, Survival and Family; Societal Plague and Women; Apartheid: Implication for Development; and Way Forward are discussed. The outcome revealed the difficulty of transforming South Africa into a complete liberal society due to racism and the need to empower women. The conclusions are: Education should be made accessible to all; Women empowered and total freedom restored.展开更多
The native extracellular matrix (ECM) and the cells that comprise human tissues are together engaged in a complex relationship; cells alter the composition and structure of the ECM to regulate the material and biolo...The native extracellular matrix (ECM) and the cells that comprise human tissues are together engaged in a complex relationship; cells alter the composition and structure of the ECM to regulate the material and biologic properties of the surrounding environment while the composition and structure of the ECM modulates cellular processes that maintain healthy tissue and repair diseased tissue. This reciprocal relationship occurs via cell adhesion molecules (CAMs) such as integrins, selectins, cadherins and IgSF adhesion molecules. To study these celI-ECM interactions, researchers use two-dimensional substrates or three-dimensional matrices composed of native proteins or bioactive peptide sequences to study single cell function. While two-dimensional snbstrates provide valuable information about cell-ECM interactions, three-dimensional matrices more closely mimic the native ECM; cells cultured in three-dimensional matrices have demonstrated greater cell movement and increased integrin expression when compared to cells cultured on two-dimensional substrates. In this article we review a number of cellular processes (adhesion, motility, phagocytosis, differentiation and survival) and examine the cell adhesion molecules and ECM proteins (or bioactive peptide sequences) that mediate cell functionality.展开更多
文摘The paper presents abandonment, loneliness, and desolation, which defaced wifehood institution in South African polity. The disruption of family life and lack of opportunity for personal development turned women desolate and children delinquent. The problem is the non-liberal practices in South Africa in spite of the struggle of people like Alan Paton. The objective of this paper is to study the South African society as presented by Alan Paton in line with his Liberalist Theory in order to make freedom and development achievable. The main factual points are that racism still exists; most black homes are separated; most black women are not empowered; colour segregation hinder development. The methodology adopted is the interpretation discourse of Alan Paton's Cry My Beloved Country in line with South African society. The Silent Separatist Policy, Survival and Family; Societal Plague and Women; Apartheid: Implication for Development; and Way Forward are discussed. The outcome revealed the difficulty of transforming South Africa into a complete liberal society due to racism and the need to empower women. The conclusions are: Education should be made accessible to all; Women empowered and total freedom restored.
文摘The native extracellular matrix (ECM) and the cells that comprise human tissues are together engaged in a complex relationship; cells alter the composition and structure of the ECM to regulate the material and biologic properties of the surrounding environment while the composition and structure of the ECM modulates cellular processes that maintain healthy tissue and repair diseased tissue. This reciprocal relationship occurs via cell adhesion molecules (CAMs) such as integrins, selectins, cadherins and IgSF adhesion molecules. To study these celI-ECM interactions, researchers use two-dimensional substrates or three-dimensional matrices composed of native proteins or bioactive peptide sequences to study single cell function. While two-dimensional snbstrates provide valuable information about cell-ECM interactions, three-dimensional matrices more closely mimic the native ECM; cells cultured in three-dimensional matrices have demonstrated greater cell movement and increased integrin expression when compared to cells cultured on two-dimensional substrates. In this article we review a number of cellular processes (adhesion, motility, phagocytosis, differentiation and survival) and examine the cell adhesion molecules and ECM proteins (or bioactive peptide sequences) that mediate cell functionality.