Systemic disease can produce changes in the nails.Perhaps the best known example of this is koilonychia as a sequale of iron deficiency anemia.“ Half and half nail” is a type of pseudoleuconychia that can be caused ...Systemic disease can produce changes in the nails.Perhaps the best known example of this is koilonychia as a sequale of iron deficiency anemia.“ Half and half nail” is a type of pseudoleuconychia that can be caused by chronic renal disease,Kawasaki’s disease,cirrhosis,and zinc deficiency.It has not been described in patients with Crohn’s disease yet.Four male patients with Crohn’s disease were observed.None of them had extraintestinal manifestations of Crohn’s disease.The average duration of the disease was 5.25(range,1-10) years.The nail alterations were defined with a portion of the nail being as much as 15 to 40 percent of normal color distally,whereas the rest of the nail was white.The contrast between the two zones remains sharply demarcated even after constricting venous return.Histologic examination was not performed.Every patient had zinc deficiency but not hypalbuminaemia or sideropenia.After review of relevant literature(MEDLINE,PubMed,etc.) ,we found that half-and-half nail had not been described in Crohn’s disease.This study was designed to highlight the fact that the half-and-half nail,which was thought to be a sign of chronic renal failure,also occurs in patients with Crohn’s disease.The relationship of this symptom to clinical activity cannot yet be assessed and has only been observed in four cases.展开更多
A new organic cathode namely potassium 2,6-dihydroxyanthraquinone(AQ26OK,theoretical capacity(CT)=169 mA h g^(-1))is synthesized and fully characterized for Kion batteries.AQ26OK is called polyanionic organic cathode ...A new organic cathode namely potassium 2,6-dihydroxyanthraquinone(AQ26OK,theoretical capacity(CT)=169 mA h g^(-1))is synthesized and fully characterized for Kion batteries.AQ26OK is called polyanionic organic cathode because it has a polyanionic organic skeleton(-2 valent)and two strong ionic K-O bonds.Consequently,the polyanionic AQ26OK is hardly soluble into most organic liquid electrolytes.In half cells(0.3-3.4 V vs.K^(+)/K)using 1 mol L^(-1) KPF6 in dimethoxyethane,AQ26OK delivers a highly stable specific capacity of 201 mA h g^(-1)@50 mA g^(-1) over 450 cycles(4-month test)and realizes~106 mA h g^(-1) for 3200 cycles at 500 mA g^(-1).Using the reduced state(K4TP)of potassium terephthalate(K2TP)as the organic anode,the resulting K4TP Ⅱ AQ26OK organic potassium-ion batteries can display a highly stable average discharge capacity of 135 mA h g^(-1) cathodeover 250 cycles at 100 mA g^(-1) and~47 mA h g^(-1) for 1000 cycles at 500 mA g^(-1) during the working voltage of 0.01-3.1 V.To the best of our knowledge,AQ26OK is among the best stable cathodes reported for K-ion batteries.展开更多
文摘Systemic disease can produce changes in the nails.Perhaps the best known example of this is koilonychia as a sequale of iron deficiency anemia.“ Half and half nail” is a type of pseudoleuconychia that can be caused by chronic renal disease,Kawasaki’s disease,cirrhosis,and zinc deficiency.It has not been described in patients with Crohn’s disease yet.Four male patients with Crohn’s disease were observed.None of them had extraintestinal manifestations of Crohn’s disease.The average duration of the disease was 5.25(range,1-10) years.The nail alterations were defined with a portion of the nail being as much as 15 to 40 percent of normal color distally,whereas the rest of the nail was white.The contrast between the two zones remains sharply demarcated even after constricting venous return.Histologic examination was not performed.Every patient had zinc deficiency but not hypalbuminaemia or sideropenia.After review of relevant literature(MEDLINE,PubMed,etc.) ,we found that half-and-half nail had not been described in Crohn’s disease.This study was designed to highlight the fact that the half-and-half nail,which was thought to be a sign of chronic renal failure,also occurs in patients with Crohn’s disease.The relationship of this symptom to clinical activity cannot yet be assessed and has only been observed in four cases.
基金supported by the Fundamental Research Funds of University of Electronic Science and Technology of China(UESTC,ZYGX2019J027)the Open Foundation of State Key Laboratory of Electronic Thin Films and Integrated Devices of UESTC(KFJJ201915)Sichuan Science and Technology Program(20YYJC3821)。
文摘A new organic cathode namely potassium 2,6-dihydroxyanthraquinone(AQ26OK,theoretical capacity(CT)=169 mA h g^(-1))is synthesized and fully characterized for Kion batteries.AQ26OK is called polyanionic organic cathode because it has a polyanionic organic skeleton(-2 valent)and two strong ionic K-O bonds.Consequently,the polyanionic AQ26OK is hardly soluble into most organic liquid electrolytes.In half cells(0.3-3.4 V vs.K^(+)/K)using 1 mol L^(-1) KPF6 in dimethoxyethane,AQ26OK delivers a highly stable specific capacity of 201 mA h g^(-1)@50 mA g^(-1) over 450 cycles(4-month test)and realizes~106 mA h g^(-1) for 3200 cycles at 500 mA g^(-1).Using the reduced state(K4TP)of potassium terephthalate(K2TP)as the organic anode,the resulting K4TP Ⅱ AQ26OK organic potassium-ion batteries can display a highly stable average discharge capacity of 135 mA h g^(-1) cathodeover 250 cycles at 100 mA g^(-1) and~47 mA h g^(-1) for 1000 cycles at 500 mA g^(-1) during the working voltage of 0.01-3.1 V.To the best of our knowledge,AQ26OK is among the best stable cathodes reported for K-ion batteries.
