Objective To assess the efficacy and possible adverse effects of acupuncture on frozen shoulder. Methods Based on the key words, i.e. acupuncture, electroacupuncture, acupuncture-moxibustion, frozen shoulder, adhesive...Objective To assess the efficacy and possible adverse effects of acupuncture on frozen shoulder. Methods Based on the key words, i.e. acupuncture, electroacupuncture, acupuncture-moxibustion, frozen shoulder, adhesive capsulitis, shoulder disorders etc., the Chinese databases were retrieved, including Oochrane Musculoskeleta Group, Oochrane Controlled Trials Register, Oochrane Complementary Medicine Field, and the central database of the Oochrane Library as well as MEDLINE, EMBASE and Chinese Biomedical CD (OBM-disc). 20 Chinese medical journals and relevant academic conference proceedings have been searched manually. The reference lists of identified documents were checked as the supplementary retrieval. Results 6 randomized controlled trials on frozen shoulder with acupuncture and electroacupuncture were included, indicating quite advanced study quality. There were 34 to 257 participants in the trials, 668 in total. The total OR of CMS/OSA was OR 3.49 (95 % CI - 2.64 to 9.63), the total OR of VAS was OR - 1.24 (95% CI -3.50 to 1.01), the total OR of ROM was OR 35.70 (95% CI 22.91 to 48.49); the total OR of MELLE was OR 4.30 (95% OI 2.32 to 7.98). Conclusion It is shown in the present limited inclusive trials on frozen shoulder that acupuncture is the safe therapy and effective on improving the global function, relieving pain, and improving the range of motion of shoulder. All the therapeutic effects of acupuncture are superior to those in control group. However, much more high quality trials are required to provide much stronger evidence. Additionally, much more evidences on validity of frozen shoulder with other assessing indexes involved are required in the treatment with acupuncture.展开更多
The methods of moment and genetic algorithm (GA) are combined to optimize the Yagi Uda antenna array and Log periodic dipole antenna (LPDA) array. The element lengths and spacing are optimized for the Yagi Uda arra...The methods of moment and genetic algorithm (GA) are combined to optimize the Yagi Uda antenna array and Log periodic dipole antenna (LPDA) array. The element lengths and spacing are optimized for the Yagi Uda array; while the ratio factor of spacing to length as well as the ratio of length to diameter of the elements are optimized for LPDA array. The results show that the main parameters, such as gain and pattern, have been improved apparently; and the high back lobe level of LPDA can be reduced greatly, therefore, GA is a very competent method for optimizing the linear array as well as in other fields.展开更多
An efficient cycle slip detection method is proposed for high precision positioning and navigation results with global positioning system (GPS),which is based on the assumption of a high sampling interval, measureme...An efficient cycle slip detection method is proposed for high precision positioning and navigation results with global positioning system (GPS),which is based on the assumption of a high sampling interval, measurement errors are so small that they can be ignored in the temporal single difference observables. And ambiguities are ordinarily equal to zero,but could be the number of cycles that have "slipped" if loss-of-lock has occurred.Therefore,cycle slips are estimated as parameters of time-relative positioning observation equations.Because the temporal single difference observables are taken at different epochs and different stations with a single GPS receiver,if time-relative positioning observation equations are linearized as that of conventional relative positioning,the design matrix will be rank defective.To obtain a stable linearization scheme,time-relative positioning observation equations are further analyzed,and the concept of virtual measurement is applied.A sample of data collected on a vehicle test shows that a cycle slip detection approach based on time-relative positioning theory can detect slips at the value of one cycle.The results also indicate if two satellites are so near to each other that they have the same equivalent to satellite-receiver geometry,cycle slip detection will be difficult and may get wrong results.Cycle slips of different satellites also affect detection by satellite-receiver geometry.展开更多
J.Kaplan and J.Yorke's method is extended to establish the exis- tence of many and infinitely many periodic solutions for the DDEs (t) =±f(x(t-1))±f(x(t-2))and (t)=±f(x(t-1).
Photodetachment of H- irradiated by linearly polarized few-cycle laser field is investigated by time-dependent SchrSdinger equation numerically. The photo-electron left-right asymmetry parameter as a function of carri...Photodetachment of H- irradiated by linearly polarized few-cycle laser field is investigated by time-dependent SchrSdinger equation numerically. The photo-electron left-right asymmetry parameter as a function of carrier-envelop (CE) phase of few-cycle pulses is attained. We confirm the asymmetry of photoelectron distribution in H- photodetachment and find that the maximal asymmetry parameter of H- is equal to that of H atom under the same conditions but the corresponding CE phases are quite different. Thus a CE phase shift appears. Compared to that of H atom and field free electron, the zero asymmetry CE phase shift is sensitively affected by Coulomb field. The Coulomb effect on the asymmetry of H- photodetachment mainly behaves in the CE phase shift of H- instead of the amplitude of asymmetry parameter curve.展开更多
In this paper, we present an object reduction for nonlinear partial differential equations. As a concrete example of its applications in physical problems, this method is applied to the (2+1)-dimensional Boiti-Leon...In this paper, we present an object reduction for nonlinear partial differential equations. As a concrete example of its applications in physical problems, this method is applied to the (2+1)-dimensional Boiti-Leon-Pempinelli system, which has the extensive physics background, and an abundance of exact solutions is derived from some reduction equations. Based on the derived solutions, the localized structures under the periodic wave background are obtained.展开更多
Recent developments in studies of directed transport processes in interacting particle systems are retrospected. Due to the interactions among elements, the directed transport process exhibits complicated and novel co...Recent developments in studies of directed transport processes in interacting particle systems are retrospected. Due to the interactions among elements, the directed transport process exhibits complicated and novel cooperative dynamics. We considered various possibilities in achieving ratchet motion by breaking different symmetries of many-body systems. It is shown that the directional transport can even be induced by breaking the coupling symmetry and the spatiotemporal symmetries.展开更多
Litopenaeus vannamei, a euryhaline species, can be cultured at a wide range of salinities. The emergence of freshwater pond-culture ofL. vannamei is an important prelude to the continued development of shrimp culture ...Litopenaeus vannamei, a euryhaline species, can be cultured at a wide range of salinities. The emergence of freshwater pond-culture ofL. vannamei is an important prelude to the continued development of shrimp culture in China. In this study, we com- pared the respiratory metabolism of juvenile L. vannamei cultured in freshwater and saltwater by measuring their oxygen consump-tion rate (OCR), ammonium-type nitrogen excretion rate (AER) and pyruvate kinase (PK) and lactate dehydrogenase (LDH) activi-ties at different molting stages in order to physiecologically characterize juvenile L. vannamei under freshwater conditions. The re- suits showed that OCR was significantly higher in saltwater than in freshwater at all stages of molting cycle. However, variation of OCR among molting stages in saltwater was similar with that in freshwater, and the highest OCR was observed at post-molting stage. At all stages of molting cycle, AER was significantly higher in freshwater than in saltwater, and the highest was observed at post-molting stage. The activity of PK was significantly higher in saltwater than in freshwater. Conversely, the activity of LDH was higher in freshwater than in saltwater in general. Significant variation of PK and LDH activities in molting cycle was observed in saltwater and freshwater. The results indicated that aerobic metabolism of juvenile L. vannamei was more active in saltwater than in freshwater; while its protein metabolism was more active in freshwater than in saltwater.展开更多
Unidirectional transport of a particle in a spatially periodic and symmetric potential under a periodic force with broken temporal symmetry is studied. With a collaboration of the potential field and the asymmetric ac...Unidirectional transport of a particle in a spatially periodic and symmetric potential under a periodic force with broken temporal symmetry is studied. With a collaboration of the potential field and the asymmetric ac force, a dc current can be observed. Resonant current steps are found for a finite period of the ac force. A phase diagram of these resonant steps is given. Stochastic-resonance-like directional transport induced by thermal noises is revealed.展开更多
Objective: To analyze the therapeutic effect of contralateral needling in the treatment of scapulohumeral periarthritis. Methods: A total of 68 cases of scapulohumeral periarthritis were outpatients and were randomize...Objective: To analyze the therapeutic effect of contralateral needling in the treatment of scapulohumeral periarthritis. Methods: A total of 68 cases of scapulohumeral periarthritis were outpatients and were randomized into treatment group (n=36) and control group (n=32). In treatment group, Zhiyin (BL 67), Jinmen (BL 63) and Yanglao (SI 6) on the contralateral side of the affected shoulder and local tenderpoints (Ashi-points) were punctured once every other day, with 7 days being a therapeutic course; while in control group, local Ashi-points were used for injection of Procaine and Prednisolone Acetate, once every 7 days and with 3~4 sessions being a therapeutic course. Results: Following 2 courses of treatment, of the 32 cases in control group, 8 (25.0%) were cured, 17 (53.1%) experienced improvement and 7 failed in the treatment, with a total of effective rate of 78.1%; of the 36 cases in treatment group, 18 (50.0%) were cured, 16 (44.4%) experienced improvement and 2 (5.6%) failed in the treatment, with a total effective rate of 94.4%. The therapeutic effect of contralateral needling is significantly higher than that of Ashi-point blocking method (P<0.05). Conclusion: Contralateral needling is superior to Ashi-point in the treatment of scapulohumeral periarthritis.展开更多
The article concerns the commission that was made by the Biennale di Venezia to Stravinsky in the 50s' which led to the composition of the Canticum Sacrum. The discovery of the correspondence between the composer, th...The article concerns the commission that was made by the Biennale di Venezia to Stravinsky in the 50s' which led to the composition of the Canticum Sacrum. The discovery of the correspondence between the composer, the artistic director Alessandro Piovesan and the organizers of the Venetian Festival allows to reconstruct the events that led Stravinsky to change his initial plans for a Passion selon Saint Marc in favour of a short Canticum. The objections, which concerned above all the limited size of the piece, were repeated several times by Piovesan, but were all disregarded by Stravinsky. In the light of the eight letters deposited in the Archivio Storico delle Arti Contemporanee (ASAC) of Venice (in Appendix), the circumstances bringing about Stravinsky's refusal can be fully understood. The references to recent studies by David H. Smyth, Akane Mori, and Jonathan Kramer regarding the identification of palindromic and proportional structures in the Canticum, offers further proof sustaining Stravinsky's declaration that to enlarge the piece would have been impossible. These events confirm the composer's unbending determination to undertake a new experimental stylistic direction already tried out in pieces like the Three Songs from William Shakespeare and Agon.展开更多
Objective: The aim of the study was to investigate the impact of 60Co y-ray on apoptosis, cell cycles and the expression of protein hypoxia-inducible factor-1α (HIF-1α) to Hep-2 cell line in the conditions of nor...Objective: The aim of the study was to investigate the impact of 60Co y-ray on apoptosis, cell cycles and the expression of protein hypoxia-inducible factor-1α (HIF-1α) to Hep-2 cell line in the conditions of normoxia and hypoxia. Methods: Hep-2 cell were divided into 2 groups: group A (normoxia) and group B (hypoxia). All of the ceils were exposed to y-ray with dosage being 0, 1, 3, 5, 10, 20, and 40 Gy. Flow cytometry was used to measure the protein level of HIF-1α and to detect apoptosis and cell cycles. The protein level of HIF-1α was also determined by immunohistochemistry and Western blotting. Results: The protein level of HIF-1α in group B was significantly higher than that in group A. In group A, low doses (1-5 Gy) of y-ray had caused G0/G1 cell cycle arrest and high doses (10-40 Gy) had caused G2/M cell cycle arrest. In group B, without exposure of y-ray (0 Gy) had caused G0/G1 cell cycle arrest, all of the different dosage of y-ray could cause G2/M cell cycle arrest. The curve of apoptosis rate in group A was a parabola, the apoptotic rate was related to the dosage of y-ray in a dosage dependent manner. The peak was at the point of 5 Gy. The apoptosis rate in group A was significantly higher than that in group B. Conclusion: Different doses of y-ray could cause different cell cycles arrest then make different impact on apoptosis to Hep-2 ceil. The lower apoptosis rate in condition of hypoxia maybe has a relationship with G2/M cell cycle arrest. Up-regulated HIF-1α protein may be one of the reasons for G2/M cell cycle arrest.展开更多
Disintegration of rock is one of the primary processes of soil formation and geomorphology and is affected considerably by water and heat.This study focused on the disintegration characteristics under laboratory condi...Disintegration of rock is one of the primary processes of soil formation and geomorphology and is affected considerably by water and heat.This study focused on the disintegration characteristics under laboratory conditions of typical purple mudstone from the Tuodian group of Jurassic red beds(J3t) in Tuodian Town,Shuangbai county,Yunnan Province of southern China.The fresh mudstone was subjected to alternating applications of water,heat and hydrothermal interaction during five treatments:wetting-drying(WD),saturation(ST),refrigeration-heating(RH),a combination of wetting-drying and refrigeration-heating(WDRH),and a combination of saturation and refrigeration-heating(STRH).Each treatment was run in twenty-four cycles.The results showed that there are three types of disintegration:collapsing disintegration,exfoliation disintegration and imperceptible disintegration.The cumulative disintegration rate(percentage of cumulative disintegrated mass to the initiative sample mass passed through a 2 mm sieve) produced a 'S'-shape function when related to treatment cycle time and closely fit a logistic model(R2 > 0.99).The rank order of the cumulative disintegration rate resulting from the five treatments was as the following:WDRH > STRH > ST > WD > RH.Because of alternating periods of moisture and dryness,WD caused the most disintegration,while RH alone resulted in imperceptible disintegration.Additionally,there was a negative correlation between the disintegration rate of each treatment cycle(percentage of disintegrated mass to the treated sample mass) and treatment cycle number.There was a positive correlation between this rate and temperature change under moist conditions,indicating that a change in temperature greatly accelerates the disintegration of parent rock when water was supplied.展开更多
In the paper, we study a super-conducting junctions device subject to an input periodic signal and a constant force. It is shown that, for this device, we can get current reversals for the current of the electron pair...In the paper, we study a super-conducting junctions device subject to an input periodic signal and a constant force. It is shown that, for this device, we can get current reversals for the current of the electron pairs versus the frequency of the periodic signal and negative conductance for the current of the electron pairs as a function of the constant force.展开更多
Within the wide distribution of Lenkoran in Iran, populations of the species inhabit variety of habitats. The authors hypothesized that each river may contribute to habitat-specific variation in life history of the fi...Within the wide distribution of Lenkoran in Iran, populations of the species inhabit variety of habitats. The authors hypothesized that each river may contribute to habitat-specific variation in life history of the fish. To test this, a total of 378 specimens of Capoeta capoeta gracilis caught in the Atrak river (northern Iran) from Dec. 2007 to Nov. 2008 were examined for life history attributes. The population has a 5-year life cycle. Weight-length relationship (WLR) was estimated as W = 0.0127TL28981 for males, W = 0.0083TL3998 for females and W = 0.0084TL3942 for the population, being allometric negative for males and positive for females and the population. The VBGF fit to back-calculated size at age data were: Lt = 22.11 (1-e-0.19(t+135)), Lt = 25.37 (1-e-0.18(t+125)) and Lt = 24.92 (1-e-018(1+122)) for males, females and sexes combined respectively. Sex ratio was significant from the parity, females dominated. The reproductive season, evaluated from GSI, extended from Apr. to July, with the highest peak in May for males and in Apr. for females. The absolute fecundity ranged between 458-5,743 eggs with a mean of 1,375.06 eggs. Fecundity relative to total weight fluctuated from 14.90 to 132.58, with a mean value of 48.79 eggs·g-1. The diameter of oocytes ranged from 0.53 to 2.40 mm with a mean value of 1.46. The life history patterns of C. c. gracilis in the considered population imply that the many population characteristics of this species in the river differ markedly from those of other rivers of its range distribution in northern Iran. Probably, respond to environmental characteristics to improve fitness locally is the more suitable choice for differentiated life history strategies of the species in the river.展开更多
文摘Objective To assess the efficacy and possible adverse effects of acupuncture on frozen shoulder. Methods Based on the key words, i.e. acupuncture, electroacupuncture, acupuncture-moxibustion, frozen shoulder, adhesive capsulitis, shoulder disorders etc., the Chinese databases were retrieved, including Oochrane Musculoskeleta Group, Oochrane Controlled Trials Register, Oochrane Complementary Medicine Field, and the central database of the Oochrane Library as well as MEDLINE, EMBASE and Chinese Biomedical CD (OBM-disc). 20 Chinese medical journals and relevant academic conference proceedings have been searched manually. The reference lists of identified documents were checked as the supplementary retrieval. Results 6 randomized controlled trials on frozen shoulder with acupuncture and electroacupuncture were included, indicating quite advanced study quality. There were 34 to 257 participants in the trials, 668 in total. The total OR of CMS/OSA was OR 3.49 (95 % CI - 2.64 to 9.63), the total OR of VAS was OR - 1.24 (95% CI -3.50 to 1.01), the total OR of ROM was OR 35.70 (95% CI 22.91 to 48.49); the total OR of MELLE was OR 4.30 (95% OI 2.32 to 7.98). Conclusion It is shown in the present limited inclusive trials on frozen shoulder that acupuncture is the safe therapy and effective on improving the global function, relieving pain, and improving the range of motion of shoulder. All the therapeutic effects of acupuncture are superior to those in control group. However, much more high quality trials are required to provide much stronger evidence. Additionally, much more evidences on validity of frozen shoulder with other assessing indexes involved are required in the treatment with acupuncture.
文摘The methods of moment and genetic algorithm (GA) are combined to optimize the Yagi Uda antenna array and Log periodic dipole antenna (LPDA) array. The element lengths and spacing are optimized for the Yagi Uda array; while the ratio factor of spacing to length as well as the ratio of length to diameter of the elements are optimized for LPDA array. The results show that the main parameters, such as gain and pattern, have been improved apparently; and the high back lobe level of LPDA can be reduced greatly, therefore, GA is a very competent method for optimizing the linear array as well as in other fields.
文摘An efficient cycle slip detection method is proposed for high precision positioning and navigation results with global positioning system (GPS),which is based on the assumption of a high sampling interval, measurement errors are so small that they can be ignored in the temporal single difference observables. And ambiguities are ordinarily equal to zero,but could be the number of cycles that have "slipped" if loss-of-lock has occurred.Therefore,cycle slips are estimated as parameters of time-relative positioning observation equations.Because the temporal single difference observables are taken at different epochs and different stations with a single GPS receiver,if time-relative positioning observation equations are linearized as that of conventional relative positioning,the design matrix will be rank defective.To obtain a stable linearization scheme,time-relative positioning observation equations are further analyzed,and the concept of virtual measurement is applied.A sample of data collected on a vehicle test shows that a cycle slip detection approach based on time-relative positioning theory can detect slips at the value of one cycle.The results also indicate if two satellites are so near to each other that they have the same equivalent to satellite-receiver geometry,cycle slip detection will be difficult and may get wrong results.Cycle slips of different satellites also affect detection by satellite-receiver geometry.
文摘J.Kaplan and J.Yorke's method is extended to establish the exis- tence of many and infinitely many periodic solutions for the DDEs (t) =±f(x(t-1))±f(x(t-2))and (t)=±f(x(t-1).
文摘Photodetachment of H- irradiated by linearly polarized few-cycle laser field is investigated by time-dependent SchrSdinger equation numerically. The photo-electron left-right asymmetry parameter as a function of carrier-envelop (CE) phase of few-cycle pulses is attained. We confirm the asymmetry of photoelectron distribution in H- photodetachment and find that the maximal asymmetry parameter of H- is equal to that of H atom under the same conditions but the corresponding CE phases are quite different. Thus a CE phase shift appears. Compared to that of H atom and field free electron, the zero asymmetry CE phase shift is sensitively affected by Coulomb field. The Coulomb effect on the asymmetry of H- photodetachment mainly behaves in the CE phase shift of H- instead of the amplitude of asymmetry parameter curve.
基金The project supported by the Natural Science Foundation of Zhejiang Province under Grant No. Y604106 and the Natural Science Foundation of Zhejiang Lishui University under Grant No. FC06001
文摘In this paper, we present an object reduction for nonlinear partial differential equations. As a concrete example of its applications in physical problems, this method is applied to the (2+1)-dimensional Boiti-Leon-Pempinelli system, which has the extensive physics background, and an abundance of exact solutions is derived from some reduction equations. Based on the derived solutions, the localized structures under the periodic wave background are obtained.
文摘Recent developments in studies of directed transport processes in interacting particle systems are retrospected. Due to the interactions among elements, the directed transport process exhibits complicated and novel cooperative dynamics. We considered various possibilities in achieving ratchet motion by breaking different symmetries of many-body systems. It is shown that the directional transport can even be induced by breaking the coupling symmetry and the spatiotemporal symmetries.
基金supported by National Program on Key Basic Research Project (Grant No.2009CB118706)
文摘Litopenaeus vannamei, a euryhaline species, can be cultured at a wide range of salinities. The emergence of freshwater pond-culture ofL. vannamei is an important prelude to the continued development of shrimp culture in China. In this study, we com- pared the respiratory metabolism of juvenile L. vannamei cultured in freshwater and saltwater by measuring their oxygen consump-tion rate (OCR), ammonium-type nitrogen excretion rate (AER) and pyruvate kinase (PK) and lactate dehydrogenase (LDH) activi-ties at different molting stages in order to physiecologically characterize juvenile L. vannamei under freshwater conditions. The re- suits showed that OCR was significantly higher in saltwater than in freshwater at all stages of molting cycle. However, variation of OCR among molting stages in saltwater was similar with that in freshwater, and the highest OCR was observed at post-molting stage. At all stages of molting cycle, AER was significantly higher in freshwater than in saltwater, and the highest was observed at post-molting stage. The activity of PK was significantly higher in saltwater than in freshwater. Conversely, the activity of LDH was higher in freshwater than in saltwater in general. Significant variation of PK and LDH activities in molting cycle was observed in saltwater and freshwater. The results indicated that aerobic metabolism of juvenile L. vannamei was more active in saltwater than in freshwater; while its protein metabolism was more active in freshwater than in saltwater.
文摘Unidirectional transport of a particle in a spatially periodic and symmetric potential under a periodic force with broken temporal symmetry is studied. With a collaboration of the potential field and the asymmetric ac force, a dc current can be observed. Resonant current steps are found for a finite period of the ac force. A phase diagram of these resonant steps is given. Stochastic-resonance-like directional transport induced by thermal noises is revealed.
文摘Objective: To analyze the therapeutic effect of contralateral needling in the treatment of scapulohumeral periarthritis. Methods: A total of 68 cases of scapulohumeral periarthritis were outpatients and were randomized into treatment group (n=36) and control group (n=32). In treatment group, Zhiyin (BL 67), Jinmen (BL 63) and Yanglao (SI 6) on the contralateral side of the affected shoulder and local tenderpoints (Ashi-points) were punctured once every other day, with 7 days being a therapeutic course; while in control group, local Ashi-points were used for injection of Procaine and Prednisolone Acetate, once every 7 days and with 3~4 sessions being a therapeutic course. Results: Following 2 courses of treatment, of the 32 cases in control group, 8 (25.0%) were cured, 17 (53.1%) experienced improvement and 7 failed in the treatment, with a total of effective rate of 78.1%; of the 36 cases in treatment group, 18 (50.0%) were cured, 16 (44.4%) experienced improvement and 2 (5.6%) failed in the treatment, with a total effective rate of 94.4%. The therapeutic effect of contralateral needling is significantly higher than that of Ashi-point blocking method (P<0.05). Conclusion: Contralateral needling is superior to Ashi-point in the treatment of scapulohumeral periarthritis.
文摘The article concerns the commission that was made by the Biennale di Venezia to Stravinsky in the 50s' which led to the composition of the Canticum Sacrum. The discovery of the correspondence between the composer, the artistic director Alessandro Piovesan and the organizers of the Venetian Festival allows to reconstruct the events that led Stravinsky to change his initial plans for a Passion selon Saint Marc in favour of a short Canticum. The objections, which concerned above all the limited size of the piece, were repeated several times by Piovesan, but were all disregarded by Stravinsky. In the light of the eight letters deposited in the Archivio Storico delle Arti Contemporanee (ASAC) of Venice (in Appendix), the circumstances bringing about Stravinsky's refusal can be fully understood. The references to recent studies by David H. Smyth, Akane Mori, and Jonathan Kramer regarding the identification of palindromic and proportional structures in the Canticum, offers further proof sustaining Stravinsky's declaration that to enlarge the piece would have been impossible. These events confirm the composer's unbending determination to undertake a new experimental stylistic direction already tried out in pieces like the Three Songs from William Shakespeare and Agon.
文摘Objective: The aim of the study was to investigate the impact of 60Co y-ray on apoptosis, cell cycles and the expression of protein hypoxia-inducible factor-1α (HIF-1α) to Hep-2 cell line in the conditions of normoxia and hypoxia. Methods: Hep-2 cell were divided into 2 groups: group A (normoxia) and group B (hypoxia). All of the ceils were exposed to y-ray with dosage being 0, 1, 3, 5, 10, 20, and 40 Gy. Flow cytometry was used to measure the protein level of HIF-1α and to detect apoptosis and cell cycles. The protein level of HIF-1α was also determined by immunohistochemistry and Western blotting. Results: The protein level of HIF-1α in group B was significantly higher than that in group A. In group A, low doses (1-5 Gy) of y-ray had caused G0/G1 cell cycle arrest and high doses (10-40 Gy) had caused G2/M cell cycle arrest. In group B, without exposure of y-ray (0 Gy) had caused G0/G1 cell cycle arrest, all of the different dosage of y-ray could cause G2/M cell cycle arrest. The curve of apoptosis rate in group A was a parabola, the apoptotic rate was related to the dosage of y-ray in a dosage dependent manner. The peak was at the point of 5 Gy. The apoptosis rate in group A was significantly higher than that in group B. Conclusion: Different doses of y-ray could cause different cell cycles arrest then make different impact on apoptosis to Hep-2 ceil. The lower apoptosis rate in condition of hypoxia maybe has a relationship with G2/M cell cycle arrest. Up-regulated HIF-1α protein may be one of the reasons for G2/M cell cycle arrest.
基金supported by National Natural Science Foundation of China (Grant No.40971168)National Basic Research Program of China (973 Program) (Grant No. 2007CB407206)
文摘Disintegration of rock is one of the primary processes of soil formation and geomorphology and is affected considerably by water and heat.This study focused on the disintegration characteristics under laboratory conditions of typical purple mudstone from the Tuodian group of Jurassic red beds(J3t) in Tuodian Town,Shuangbai county,Yunnan Province of southern China.The fresh mudstone was subjected to alternating applications of water,heat and hydrothermal interaction during five treatments:wetting-drying(WD),saturation(ST),refrigeration-heating(RH),a combination of wetting-drying and refrigeration-heating(WDRH),and a combination of saturation and refrigeration-heating(STRH).Each treatment was run in twenty-four cycles.The results showed that there are three types of disintegration:collapsing disintegration,exfoliation disintegration and imperceptible disintegration.The cumulative disintegration rate(percentage of cumulative disintegrated mass to the initiative sample mass passed through a 2 mm sieve) produced a 'S'-shape function when related to treatment cycle time and closely fit a logistic model(R2 > 0.99).The rank order of the cumulative disintegration rate resulting from the five treatments was as the following:WDRH > STRH > ST > WD > RH.Because of alternating periods of moisture and dryness,WD caused the most disintegration,while RH alone resulted in imperceptible disintegration.Additionally,there was a negative correlation between the disintegration rate of each treatment cycle(percentage of disintegrated mass to the treated sample mass) and treatment cycle number.There was a positive correlation between this rate and temperature change under moist conditions,indicating that a change in temperature greatly accelerates the disintegration of parent rock when water was supplied.
基金supported by National Natural Science Foundation of ChinaK.C.Wong Magna Fund in Ningbo University of Chinathe Natural Science Foundation of Ningbo in China
文摘In the paper, we study a super-conducting junctions device subject to an input periodic signal and a constant force. It is shown that, for this device, we can get current reversals for the current of the electron pairs versus the frequency of the periodic signal and negative conductance for the current of the electron pairs as a function of the constant force.
文摘Within the wide distribution of Lenkoran in Iran, populations of the species inhabit variety of habitats. The authors hypothesized that each river may contribute to habitat-specific variation in life history of the fish. To test this, a total of 378 specimens of Capoeta capoeta gracilis caught in the Atrak river (northern Iran) from Dec. 2007 to Nov. 2008 were examined for life history attributes. The population has a 5-year life cycle. Weight-length relationship (WLR) was estimated as W = 0.0127TL28981 for males, W = 0.0083TL3998 for females and W = 0.0084TL3942 for the population, being allometric negative for males and positive for females and the population. The VBGF fit to back-calculated size at age data were: Lt = 22.11 (1-e-0.19(t+135)), Lt = 25.37 (1-e-0.18(t+125)) and Lt = 24.92 (1-e-018(1+122)) for males, females and sexes combined respectively. Sex ratio was significant from the parity, females dominated. The reproductive season, evaluated from GSI, extended from Apr. to July, with the highest peak in May for males and in Apr. for females. The absolute fecundity ranged between 458-5,743 eggs with a mean of 1,375.06 eggs. Fecundity relative to total weight fluctuated from 14.90 to 132.58, with a mean value of 48.79 eggs·g-1. The diameter of oocytes ranged from 0.53 to 2.40 mm with a mean value of 1.46. The life history patterns of C. c. gracilis in the considered population imply that the many population characteristics of this species in the river differ markedly from those of other rivers of its range distribution in northern Iran. Probably, respond to environmental characteristics to improve fitness locally is the more suitable choice for differentiated life history strategies of the species in the river.