Objective:Intertrochanteric femur fracture is a common injury in elderly patients.The dynamic hip screw (DHS) has served as the standard choice for fixation; however it has several drawbacks.Studies of the percutan...Objective:Intertrochanteric femur fracture is a common injury in elderly patients.The dynamic hip screw (DHS) has served as the standard choice for fixation; however it has several drawbacks.Studies of the percutaneous compression plate (PCCP) are still inconclusive in regards to its efficacy and safety.By comparing the two methods,we assessed their clinical therapeutic outcome.Methods:Atotal of 121 elderly patients with intertrochanteric femur fractures (type AO/OTA 31.A 1-A2,Evans type 1) were divided randomly into two groups undergoing either a minimally invasive PCCP procedure or a conventional DHS fixation.Results:The mean operation duration was significantly shorter in the PCCP group (55.2 min versus 88.5 min,P<0.01).The blood loss was 156.5 ml±18.3 ml in the PCCP group and 513.2 ml±66.2 ml in the DHS group (P<0.01).Among the patients treated with PCCP,3.1% needed blood transfusions,compared with 44.6% of those that had DHS surgery (P<0.01).The PCCP group displayed less postoperative complications (P<0.05).The mean American Society of Anesthesiologists score and Harris hip score in the PCCP group were better than those in the DHS group.There were no significant differences in the mean hospital stay,mortality rates,or fracture healing.Conclusion:Due to several advantages,PCCP has the potential to become the ideal choice for treating intertrochanteric fractures (type AO/OTA 31.A1-A2,Evans type 1),particularly in the elderly.展开更多
Objective:To explore the efficacy and mechanism of warm needling moxibustion plus percutaneous kyphoplasty(PKP)for osteoporotic vertebral compression fracture(OVCF)due to kidney deficiency and blood stasis.Methods:A t...Objective:To explore the efficacy and mechanism of warm needling moxibustion plus percutaneous kyphoplasty(PKP)for osteoporotic vertebral compression fracture(OVCF)due to kidney deficiency and blood stasis.Methods:A total of 70 OVCF patients were randomized into a control group and an observation group,with 35 cases in each group.The control group was given PKP treatment,and the observation group was treated with warm needling moxibustion on the basis of the treatment in the control group.The visual analog scale(VAS)and Oswestry disability index(ODI)were scored and the Cobb angle of fractured vertebrae was measured before and after treatment.The re-fracture rate of the adjacent vertebrae was recorded at 1-year follow-up.The serum levels of transforming growth factor(TGF)-β1 and omentin-1 were measured before and after treatment.Results:After treatment,the VAS and ODI scores in both groups decreased(all P<0.05),and all the scores in the observation group were lower than those in the control group(both P<0.05).After treatment,the Cobb angle of fractured vertebrae in both groups decreased(both P<0.05),and the Cobb angle in the observation group was smaller than that in the control group(P<0.05).At 1-year follow-up,the re-fracture rate of the adjacent vertebrae in the observation group was lower than that in the control group(P<0.05).After treatment,the serum levels of TGF-β1 and omentin-1 in both groups increased significantly(all P<0.05),and the serum levels of TGF-β1 and omentin-1 in the observation group were higher than those in the control group(both P<0.05).Conclusion:The treatment of warm needling moxibustion plus PKP can relieve pain,improve dysfunction,promote healing of the injured vertebrae,and reduce the re-fracture rate of the adjacent vertebrae in patients with OVCF due to kidney deficiency and blood stasis,which may be related to the increase of serum TGF-β1 and omentin-1 levels.展开更多
Objective:To compare the treating effects of different intramedullary nailing methods on tibial fractures in adults.Methods:Literature reports in both Chinese and English languages were retrieved (from the earliest...Objective:To compare the treating effects of different intramedullary nailing methods on tibial fractures in adults.Methods:Literature reports in both Chinese and English languages were retrieved (from the earliest available records to October 1,2013) from the PubMed,FMJS,CNKI,Wanfang Data using randomized controlled trials (RCTs) to compare reamed and unreamed intramedullary nailing for treatment of tibial fractures.Methodological quality of the trials was critically assessed,and relevant data were extracted.Statistical software Revman 5.0 was used for data-analysis.Results:A total of 12 randomized controlled trials,comprising 985 patients (475 in the unreamed group and 510 in the reamed group),were eligible for inclusion in this meta-analysis.The results of metaanalysis showed that there were no statistically significant differences between the two methods in the reported outcomes of infection (RR=0.64; 95%CI,0.39 to 1.07;P=0.09),compartment syndrome (RR=1.44; 95%CI,0.8to 2.41; P=0.16),thrombosis (RR=1.29; 95%CI,0.43to 3.87; P=0.64),time to union (WMD=5.01; 95%CI,-1.78 to 11.80; P=0.15),delayed union (nonunion)(RR=1.56; 95%CI,0.97 to 2.49; P=0.06),malunion (RR=1.75; 95%CI,1.00 to 3.08; P=0.05) and knee pain (RR=0.94; 95%CI,0.73 to 1.22; P=0.66).But there was a significantly higher fixation failure rate in the unreamed group than in the reamed group (RR=4.29; 95%CI,2.58to 7.14; P<0.00001).Conclusion:There is no significant difference in the reamed and unreamed intramedullary nailing for the treatment of tibial fractures,but our result recommends reamed nails for the treatment of closed tibial fractures for their lower fixation failure rate.展开更多
文摘Objective:Intertrochanteric femur fracture is a common injury in elderly patients.The dynamic hip screw (DHS) has served as the standard choice for fixation; however it has several drawbacks.Studies of the percutaneous compression plate (PCCP) are still inconclusive in regards to its efficacy and safety.By comparing the two methods,we assessed their clinical therapeutic outcome.Methods:Atotal of 121 elderly patients with intertrochanteric femur fractures (type AO/OTA 31.A 1-A2,Evans type 1) were divided randomly into two groups undergoing either a minimally invasive PCCP procedure or a conventional DHS fixation.Results:The mean operation duration was significantly shorter in the PCCP group (55.2 min versus 88.5 min,P<0.01).The blood loss was 156.5 ml±18.3 ml in the PCCP group and 513.2 ml±66.2 ml in the DHS group (P<0.01).Among the patients treated with PCCP,3.1% needed blood transfusions,compared with 44.6% of those that had DHS surgery (P<0.01).The PCCP group displayed less postoperative complications (P<0.05).The mean American Society of Anesthesiologists score and Harris hip score in the PCCP group were better than those in the DHS group.There were no significant differences in the mean hospital stay,mortality rates,or fracture healing.Conclusion:Due to several advantages,PCCP has the potential to become the ideal choice for treating intertrochanteric fractures (type AO/OTA 31.A1-A2,Evans type 1),particularly in the elderly.
文摘Objective:To explore the efficacy and mechanism of warm needling moxibustion plus percutaneous kyphoplasty(PKP)for osteoporotic vertebral compression fracture(OVCF)due to kidney deficiency and blood stasis.Methods:A total of 70 OVCF patients were randomized into a control group and an observation group,with 35 cases in each group.The control group was given PKP treatment,and the observation group was treated with warm needling moxibustion on the basis of the treatment in the control group.The visual analog scale(VAS)and Oswestry disability index(ODI)were scored and the Cobb angle of fractured vertebrae was measured before and after treatment.The re-fracture rate of the adjacent vertebrae was recorded at 1-year follow-up.The serum levels of transforming growth factor(TGF)-β1 and omentin-1 were measured before and after treatment.Results:After treatment,the VAS and ODI scores in both groups decreased(all P<0.05),and all the scores in the observation group were lower than those in the control group(both P<0.05).After treatment,the Cobb angle of fractured vertebrae in both groups decreased(both P<0.05),and the Cobb angle in the observation group was smaller than that in the control group(P<0.05).At 1-year follow-up,the re-fracture rate of the adjacent vertebrae in the observation group was lower than that in the control group(P<0.05).After treatment,the serum levels of TGF-β1 and omentin-1 in both groups increased significantly(all P<0.05),and the serum levels of TGF-β1 and omentin-1 in the observation group were higher than those in the control group(both P<0.05).Conclusion:The treatment of warm needling moxibustion plus PKP can relieve pain,improve dysfunction,promote healing of the injured vertebrae,and reduce the re-fracture rate of the adjacent vertebrae in patients with OVCF due to kidney deficiency and blood stasis,which may be related to the increase of serum TGF-β1 and omentin-1 levels.
文摘Objective:To compare the treating effects of different intramedullary nailing methods on tibial fractures in adults.Methods:Literature reports in both Chinese and English languages were retrieved (from the earliest available records to October 1,2013) from the PubMed,FMJS,CNKI,Wanfang Data using randomized controlled trials (RCTs) to compare reamed and unreamed intramedullary nailing for treatment of tibial fractures.Methodological quality of the trials was critically assessed,and relevant data were extracted.Statistical software Revman 5.0 was used for data-analysis.Results:A total of 12 randomized controlled trials,comprising 985 patients (475 in the unreamed group and 510 in the reamed group),were eligible for inclusion in this meta-analysis.The results of metaanalysis showed that there were no statistically significant differences between the two methods in the reported outcomes of infection (RR=0.64; 95%CI,0.39 to 1.07;P=0.09),compartment syndrome (RR=1.44; 95%CI,0.8to 2.41; P=0.16),thrombosis (RR=1.29; 95%CI,0.43to 3.87; P=0.64),time to union (WMD=5.01; 95%CI,-1.78 to 11.80; P=0.15),delayed union (nonunion)(RR=1.56; 95%CI,0.97 to 2.49; P=0.06),malunion (RR=1.75; 95%CI,1.00 to 3.08; P=0.05) and knee pain (RR=0.94; 95%CI,0.73 to 1.22; P=0.66).But there was a significantly higher fixation failure rate in the unreamed group than in the reamed group (RR=4.29; 95%CI,2.58to 7.14; P<0.00001).Conclusion:There is no significant difference in the reamed and unreamed intramedullary nailing for the treatment of tibial fractures,but our result recommends reamed nails for the treatment of closed tibial fractures for their lower fixation failure rate.