三种混凝剂处理煤泥水的对比试验研究

本文介绍了石灰、电石渣及CaCl2 分别与聚丙烯酰胺联用处理煤泥水的对比试验研究结果。结果表明 ,三种方法对煤泥水均有较好的处理效果 ,其中CaCl2 法效果最好 ,但药剂费也最高 ,石灰法和电石渣法处理效果相差不大 ,但电石渣法药剂费较低。

Clinical observation of acupuncture combined with medication for mild-to-moderate depression

Objective:To discuss the clinical efficacy and plausible mechanism of Tiao Yang Qu Xie(regulating Yang to eliminate pathogenic factors)needling method plus paroxetine in treating mild-to-moderate depression.Methods:Sixty-six patients with mild-to-moderate depression were divided into an observation group and a control group using the random number table method,each consisting of 33 cases.Another 25 healthy subjects were recruited as a healthy group.The control group took oral paroxetine tablets for treatment,and the observation group received additional acupuncture treatment 3 times weekly.Both groups underwent 4-week treatment.Before treatment,after 2-week and 4-week treatment,and 2 weeks after treatment(follow-up),the patients were assessed using the Hamilton depression scale-17-item(HAMD-17),self-rating depression scale(SDS),self-rating anxiety scale(SAS),and traditional Chinese medicine(TCM)pattern element identification scale for depression.The two groups each randomly contributed 25 cases to detect the protein content of brain-derived neurotrophic factor(BDNF)before treatment and after 4-week treatment,and compared with the healthy group.Results:After 2-week treatment,the markedly effective and total effective rates were significantly higher in the observation group than in the control group(P<0.05);after 4-week treatment,the observation group significantly surpassed the control group in comparing the markedly effective rate(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the HAMD-17 total score and sleep disorder factor score were lower in the observation group than in the control group(P<0.05);the anxiety-somatic score was lower in the observation group than in the control group after 2-week treatment(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the observation group was lower than the control group in comparing the scores of SDS,SAS,and TCM pattern element identification scale for depression(P<0.05).After 4-week treatment,the observation group had an increased serum BDNF protein content,higher than that in the control group(P<0.05)and had no significant difference compared to the healthy group(P>0.05).Conclusion:Compared to the use of oral paroxetine alone,acupuncture plus paroxetine can produce more significant efficacy in treating mild-to-moderate depression and act faster in improving sleep disorder and anxiety-somatic symptoms;increasing the serum BDNF protein content may be a part of the mechanism underlying its antidepressant actions.

Acupuncture for Primary Dysmenorrhea: A Randomized Controlled Trial

Objective： To observe the clinical therapeutic effects of acupuncture treatment for primary dysmenorrhea. Methods： 122 cases of primary dysmenorrhea were randomly divided into three groups. Fifty-two cases in the acupuncture group were treated with acupuncture. Forty cases in the medication group were treated with oral administration of Ibuprofen. Thirty cases in the placebo group were treated with oral administration of vitamin B1. The therapeutic effects were observed after treatments for three menstrual cycles. Results： The total effective rate was 96.2% in the acupuncture group, 80.0% in the medication group and 13.3% in the placebo group. By statistical management, the differences among the acupuncture group, the medication group, and placebo group were statistically significant （P〈0.05）. Conclusion： Both acupuncture and western medication are effective for primary dysmenorrhea and acupuncture treatment is better than Ibuprofen

Meta-analysis of mNGF therapy for peripheral nerve injury： a systematic review

Objective： To assess the efficacy and safety of mouse nerve growth factor （mNGF） in patients with peripheral nerve injury. Methods： Such electronic database as Cochrane Library （Issue 1,2011）, Medline （1950-2011）, Embase （1980- 2011）, National Knowledge Infrastructure （ 1979 -2011 ） were searched and meanwhile relevant journals such as Chinese Journal of Orthopaedics, Chinese Journal of Microsurgery, Chinese Journal of Neurosurgery, ere were searched as well to collect all randomized controlled trials and quasi-randomi- zed controlled trials of mNGF on patients with peripheral nerve injury. The quality of included studies was assessed according to the criteria recommended by the Cochrane Handbook for Systematic Reviews of Interventions and the data were extracted by two reviewers independently. Meta- analysis was conducted by RevMan 5.1 software. Results： Forty-one studies involving 3 304 patients with peripheral nerve injury were included. The results of meta-analysis showed that： （1） the total effective rate ofperipheral nerve injury treatment in mNGF group was obviously higher than that in control group （OR=6.36, 95% C1 4.96-8.15, P〈0.01）; （2） the scores of activities of daily living （ADL） in mNGF group was significantly higher than that in control group （weighted mean difference=1.97, 95% CI 1.33- 2.61, P〈 0.0 l）; （3） the incidence of adverse reaction in mNGF group was higher than that in control group, （OR= 1.66, 95% CI 1.61-2.38, P=0.006）, but the adverse effects were mild, which could be relieved without specific treatment or just given symptomatic treatment, and disappeared at the end of treatment. Conclusions： The mNGF therapy is effective for peripheral nerve injury. It can obviously improve patient＇s ADL. Though the incidence of adverse reaction in mNGF treatment group is higher than that in control group, this does not influence the treatment outcomes.

Influence of acupuncture on neural movement function in rats with middle cerebral artery occlusion-A randomized controlled trial

OBJECTIVES:To observe recovery in movement function in rats with middle cerebral artery occlusion(MCAO) after acupuncture treatment.METHODS:According to the randomized and controlled principle 1384 rats were divided into the ba-sic control group(including the normal,sham,model control,model without intervention,Nimodipine,and para-Renzhong groups) and the acupuncture group(including the Neiguan(PC 6),Weizhong(BL 40),Sanyinjiao(SP 6),Chize(LU 5),Renzhong(GV 6) and non-acupoint groups).MCAO was modeled by Zea-longa's thread ligation and rats with scores of 1-3,as assessed by Zausinger's six-point method,were used in this study.Moreover,in the acupuncture group each acupoint was set with 12 different parameters by the orthogonal intersection method,resulting in 78 groups with 18 rats per group.The rats were treated by acupuncture once every 12 h for a total of six sessions and neurobehavioral scores were measured after each session.The neurobehavioral scores were compared by one-way ANOVA using the statistical software SPSS 17.0.RESULTS:After acupuncture therapy the mean neurobehavioral scores in MCAO rats increased gradually at each time point with a significant difference among the six scores,but with no significant differences between the fourth(48 h) and the fifth score(60 h),and between the fifth(60 h) and the sixth(72 h) score(P > 0.05).CONCLUSIONS:MCAO rats gradually recovered movement function over multiple acupuncture sessions.After the fouth acupuncture session(48 h),the neurobehavioral scores of rats with cerebral infarction remained stable.Acupuncture treatment had a reliable curative effect on movement function in cerebral infarction rats.

Ear Acupuncture for Perimenopause Syndrome:A Multi-centered Randomized Controlled Trial

Objective： To observe and evaluate the clinical effect of ear acupuncture in treating perimenopause syndrome. Methods： A multi-centered randomized controlled trial was conducted and the enrolled participants were divided into an ear acupuncture group and a control group. The ear acupuncture group was treated by electroacupuncture at auricular points, and the control one was prescribed for Geng Nian An （Menopause Helper） tablets. The therapeutic effects were evaluated after 10-day treatments. Results： For pre-menopausal patients, the total effective rate was 96.8% in the ear acupuncture group, versus 56.3% in the control. For post-menopausal patients, the total effective rate was 85.7% in the ear acupuncture group, versus 53.0% in the control. Conclusion： Both ear acupuncture and Geng Nian An （Menopause Helper） tablets were effective in ameliorating symptoms of perimenopause syndrome, with satisfactory compliance and safety. The clinical effect of ear acupuncture is better than that of Geng Nian An （Menopause Helper） tablets.

Is fire needle superior to Western medication for herpes zoster?A systematic review and meta-analysis

Objective:To compare the effectiveness of fire needle versus Western medicine in the treatment of herpes zoster.Methods:Randomized controlled trials comparing fire needle with Western medicine in the treatment of herpes zoster were identified using 8 databases.A meta-analysis was performed using RevMan 5.3 software.Results:Eight trials involving 569 patients were included in this meta-analysis,and the results showed that fire needle was superior to Western medicine comparing the effective rate[risk ratio(RR)=1.13,95%confidence interval(Cl):1.06 to 1.20;P=0.0002],the visual analog scale(VAS)score[mean difference(MD)=-7.95;95%Cl:-10.71 to-5.20;P<0.00001],time of pain disappearance(MD=-7.61;95%CI:-9.38 to-5.84;P<0.00001),time of blister-stop(MD=-1.34,95%CI:-1.51 to-1.18;P<0.00001),time of crusted scab(MD=-2.92,95%CI:-3.62 to-2.23;P<0.00001);and time of scab off(MD=-4.64,95%CI:-5.83 to-3.46;P<0.00001).In addition,a significantly lower incidence of postherpetic neuralgia was found in the fire needle group in 30 d(RR=0.23,95%CI:0.11 to 0.51;P=0.0002)and 60 d(RR=0.33,95%CI:0.12 to 0.91;P=0.03)after treatment.Conclusion:Fire needle has a favorable effect in increasing the effective rate,relieving pain,recovering skin lesions and decreasing incidence of postherpetic neuralgia in the treatment of herpes zoster.However,considering the limitations in this study,the findings should be interpreted cautiously.

Effectiveness of external Sanjierupi Gao on mastalgia caused by mammary gland hyperplasia: a placebo controlled trial

OBJECTIVE:To evaluate the curative effect of external application of the Chinese drug,Sanjierupi Gao,on mastalgia caused by mammary gland hyperplasia.METHODS:This randomized,double-blinded,and placebo controlled study enrolled 260 patients with mammary gland hyperplasia from five hospitals.Patients were randomly and equally divided in-to a Sanjierupi Gao treatment group and a placebo control group.An adhesive plaster was applied to the most painful area on either breast for 7 h a day.Treatment lasted for two menstrual cycles without application during menstruation.Mastalgia was used as the main index of curative effect.The change before and after treatment in days of mastalgia,the time to alleviate pain,pain extent,and severe pain scores were observed.RESULTS:Compared to the control group,the treatment group had significantly fewer days of mastalgia(P<0.01),a significantly lower severe pain score(P<0.01),and significantly less subjective pain and tenderness(P<0.05 and P<0.01,respectively).Three days before the follow-up visit,the pain score in the treatment group was significantly lower than that in the control group(P<0.05).A non-parametric test was used to compare the time to alleviate mastalgia between the two groups and found no statistical difference(Z=0.313,P=0.754).CONCLUSION:Application of Sanjierupi Gao can decrease mastalgia duration in patients with mammary gland hyperplasia during menstruation and alleviate the extent of mastalgia.The time to alleviate pain is psychologically influenced.

Therapeutic effects of acupuncture for neurogenic dysphagia-a randomized controlled trial

OBJECTIVE:To evaluate the therapeutic effects and long-term efficacy of acupuncture for neurogenic dysphagia.METHODS:Subjects with neurogenic dysphagia undergoing routine swallowing management were randomized to receive either 20 sessions of true acupuncture(experimental group) or sham acupuncture(control group 1) for approximately one and a half months.A third group(control group 2) comprised of non-randomized subjects with neurogenic dysphagia who received routine care were recruited from separate wards.The outcomes were assessed by the Royal Brisbane Hospital Outcome Measure for Swallowing(RBHOMS),as well as by the consistencies of ingested food and fluid.RESULTS:A total of 87 subjects(experimental group,n= 20;control group 1,n=19;control group 2,n=48) were recruited into the trial.The average RBHOMS score showed a greater improvement in the experimental group and in control group 1 than in control group 2.The average levels of foodand fluid consistencies displayed greater improvement in the experimental group than in the two control groups.CONCLUSIONS:This study demonstrates that acupuncture may have therapeutic effects and long-term efficacy for neurogenic dysphagia.However,due to an insufficient sample size and the lack of follow-up for control group 2,multi-centre trials employing a larger sample size may be required to draw concrete conclusions.

Efficacy and safety of puerarin injection in treatment of diabetic peripheral neuropathy: a systematic review and Meta-analysis of randomized controlled trials

OBJECTIVE: To systematically evaluate the clinical efficacy and safety of puerarin injection in the treatment of diabeticperi pheral neuropathy(DPN).METHODS: Randomized controlled trials investigating the efficacy of puerarin injection on DPN were searched for in China National Knowledge Infrastructure Database, Chinese Scientific Journals Database, Wanfang Database, Chinese Biomedical Literature Database, PubMed, and Cochrane Library from establishment to April 30.Two reviewers independently retrieved and extracted the information.The included studies were assessed by the Cochrane risk of bias and analyzed by Review Manager 5.2 software.RESULTS: Twenty-two studies involving 1664 participants were included. The quality of the studies was found to be relatively low. Meta-analysis showed that puerarin injection combined with western medication was more effective than conventional therapy for rate, nerve conduction velocity(NCV), and hemorheology index. Six adverse drug reactions(ADRs) from puerarin injection were reported in two studies. Reactions included facial flushing, palpitations, and pain at infusion locations. However,noserious ADRs were reported.CONCLUSION: Puerarin injection was effective for the treatment of DPN. Puerarin can improve the total effective rate, correct NCV that was decreased by diabetes, and improve the hemorheology index.Puerarin was also relatively safe clinically. However,since the articles included in the study were not high-quality, more studies should be conducted to strengthen their findings.