Aim: To determine the anatomical site and extent of electrophysiological dysfu nction in patients with ethambutol associated visual loss. Methods: A comparativ e case series. Four patients with ethambutol associated v...Aim: To determine the anatomical site and extent of electrophysiological dysfu nction in patients with ethambutol associated visual loss. Methods: A comparativ e case series. Four patients with ethambutol associated visual loss underwent mu ltifocal electroretinography (mERG). Two patients had advanced visual loss while two had early signs of toxicity. The N1-P1, N1, P1 amplitudes, N1, and P1 late ncies were compared to 10 age and sex matched controls. Results: mERG abnormalit ies were detected in the ethambutol treated patients. The N1 amplitude was signi ficantly lower in the ethambutol treated patients than in the control group. Con clusion: Ethambutol is possibly toxic to the retina, and not only the optic nerv e. The multifocal ERG may be of value to diagnose and monitor patients taking et hambutol.展开更多
Objective： To observe the clinical effect of mild moxibustion plus acupoint injection for optic atrophy. Methods： Ninety-four patients with optic atrophy were divided into a treatment group （51 cases） and a contr...Objective： To observe the clinical effect of mild moxibustion plus acupoint injection for optic atrophy. Methods： Ninety-four patients with optic atrophy were divided into a treatment group （51 cases） and a control group （43 cases）. The treatment group was treated with mild moxibustion plus acupoint injection, and the control group was treated with medications. After three courses, the change of vision was observed. Results： The total effective rate was 82.4% in the treatment group and 41.9% in the control group, with a statistical difference between the two groups （P〈O.05）. Conclusion： Moxibustion plus acupoint injection is an effective method to treat optic atrophy.展开更多
文摘Aim: To determine the anatomical site and extent of electrophysiological dysfu nction in patients with ethambutol associated visual loss. Methods: A comparativ e case series. Four patients with ethambutol associated visual loss underwent mu ltifocal electroretinography (mERG). Two patients had advanced visual loss while two had early signs of toxicity. The N1-P1, N1, P1 amplitudes, N1, and P1 late ncies were compared to 10 age and sex matched controls. Results: mERG abnormalit ies were detected in the ethambutol treated patients. The N1 amplitude was signi ficantly lower in the ethambutol treated patients than in the control group. Con clusion: Ethambutol is possibly toxic to the retina, and not only the optic nerv e. The multifocal ERG may be of value to diagnose and monitor patients taking et hambutol.
基金supported by Taihe Hospital Affiliated to Hubei Medical College
文摘Objective： To observe the clinical effect of mild moxibustion plus acupoint injection for optic atrophy. Methods： Ninety-four patients with optic atrophy were divided into a treatment group （51 cases） and a control group （43 cases）. The treatment group was treated with mild moxibustion plus acupoint injection, and the control group was treated with medications. After three courses, the change of vision was observed. Results： The total effective rate was 82.4% in the treatment group and 41.9% in the control group, with a statistical difference between the two groups （P〈O.05）. Conclusion： Moxibustion plus acupoint injection is an effective method to treat optic atrophy.
