In this study,magneto-hydrodynamics (MHD) mixed convection effects of Al2O3-water nanofluid flow over a backward-facing step were investigated numerically for various electrical conductivity models of nanofluids.A uni...In this study,magneto-hydrodynamics (MHD) mixed convection effects of Al2O3-water nanofluid flow over a backward-facing step were investigated numerically for various electrical conductivity models of nanofluids.A uniform external magnetic field was applied to the flow and strength of magnetic field was varied with different values of dimensionless parameter Hartmann number (Ha=0,10,20,30,40).Three different electrical conductivity models were used to see the effects of MHD nanofluid flow.Besides,five different inclination angles between 0°-90° is used for the external magnetic field.The problem geometry is a backward-facing step which is used in many engineering applications where flow separation and reattachment phenomenon occurs.Mixed type convective heat transfer of backward-facing step was examined with various values of Richardson number (Ri=0.01,0.1,1,10) and four different nanoparticle volume fractions (Ф=0.01,0.015,0.020,0.025) considering different electrical conductivity models.Finite element method via commercial code COMSOL was used for computations.Results indicate that the addition of nanoparticles enhanced heat transfer significantly.Also increasing magnetic field strength and inclination angle increased heat transfer rate.Effects of different electrical conductivity models were also investigated and it was observed that they have significant effects on the fluid flow and heat transfer characteristics in the presence of magnetic field.展开更多
Objective: To explore the electrophysiological proper- ties of differentiation of rat bone marrow-derived stromal stem cells (rBMSCs) to neuron-like cells in vitro by edaravone, a new type of free radical scavenger...Objective: To explore the electrophysiological proper- ties of differentiation of rat bone marrow-derived stromal stem cells (rBMSCs) to neuron-like cells in vitro by edaravone, a new type of free radical scavenger. Methods: Stromal stem cells were separated from rat bone marrow with Ficoll-Paque reagent and expanded in different culture medium in vitro, rBMSCs were induced by edaravone containing serum-free L-DMEM. Morphologic observation and Western blot analysis including the expression of Nav1.6, Kvl.2, Kv1.3, Cav1.2 were performed, and whole patch-clamp technique was used. Results: Cyton contraction and long processes were shown in differentiated stromal stem cells. Navl.6, Kvl.2, Kv 1.3 and Cav 1.2 were expressed in both differentiated and undifferentiated ceils. However, the expression of channel proteins in differentiated cells was up-regulated. Consistently, their resting potential and outward currents were also enhanced in the differentiated cells, which was especially significant in the outward rectifier potassium current. Conclusion: In vitro, neuron-like cells derived from rBMSCs, induced by edaravone, possess electrophysiological properties of neurons.展开更多
This paper presents an experimental investigation of the influence of a transversal flow deflector on the cooling of a heated block mounted on a flat plate.The deflector is inclined and therefore it guides the air flo...This paper presents an experimental investigation of the influence of a transversal flow deflector on the cooling of a heated block mounted on a flat plate.The deflector is inclined and therefore it guides the air flow to the upper surface of the block.This configuration is simulating the air-cooling of a rectangular integrated circuit or a current converter mounted on an electronic card.The electronic component is assumed dissipating low heat power,as such,air forced convection is still a sufficient cooling way even without fan or heat sink on the component.The measurements are given by hot and cold wires anemometers and by an InfraRed camera.The results give details of the effects of the deflection on the hydrodynamic and the thermal fields on and over the block for different inclination angles.They show that the deviation caused by the deflector may significantly enhance the heat transfer from the component.Deflection is also able to avoid local overheating of the electronic component.Optimum heat transfer rate and homogenised temperature are shown to be obtained with an inclination angle =30°.展开更多
文摘In this study,magneto-hydrodynamics (MHD) mixed convection effects of Al2O3-water nanofluid flow over a backward-facing step were investigated numerically for various electrical conductivity models of nanofluids.A uniform external magnetic field was applied to the flow and strength of magnetic field was varied with different values of dimensionless parameter Hartmann number (Ha=0,10,20,30,40).Three different electrical conductivity models were used to see the effects of MHD nanofluid flow.Besides,five different inclination angles between 0°-90° is used for the external magnetic field.The problem geometry is a backward-facing step which is used in many engineering applications where flow separation and reattachment phenomenon occurs.Mixed type convective heat transfer of backward-facing step was examined with various values of Richardson number (Ri=0.01,0.1,1,10) and four different nanoparticle volume fractions (Ф=0.01,0.015,0.020,0.025) considering different electrical conductivity models.Finite element method via commercial code COMSOL was used for computations.Results indicate that the addition of nanoparticles enhanced heat transfer significantly.Also increasing magnetic field strength and inclination angle increased heat transfer rate.Effects of different electrical conductivity models were also investigated and it was observed that they have significant effects on the fluid flow and heat transfer characteristics in the presence of magnetic field.
基金The work was supported by Natural Science Foundation of Guangdong Province (No.06028967, 8452402301001081 ).
文摘Objective: To explore the electrophysiological proper- ties of differentiation of rat bone marrow-derived stromal stem cells (rBMSCs) to neuron-like cells in vitro by edaravone, a new type of free radical scavenger. Methods: Stromal stem cells were separated from rat bone marrow with Ficoll-Paque reagent and expanded in different culture medium in vitro, rBMSCs were induced by edaravone containing serum-free L-DMEM. Morphologic observation and Western blot analysis including the expression of Nav1.6, Kvl.2, Kv1.3, Cav1.2 were performed, and whole patch-clamp technique was used. Results: Cyton contraction and long processes were shown in differentiated stromal stem cells. Navl.6, Kvl.2, Kv 1.3 and Cav 1.2 were expressed in both differentiated and undifferentiated ceils. However, the expression of channel proteins in differentiated cells was up-regulated. Consistently, their resting potential and outward currents were also enhanced in the differentiated cells, which was especially significant in the outward rectifier potassium current. Conclusion: In vitro, neuron-like cells derived from rBMSCs, induced by edaravone, possess electrophysiological properties of neurons.
基金support of the Comité Mixte Franco-Tunisien pour la Coopération Universitaire(ProjectCMCU 08G1131)
文摘This paper presents an experimental investigation of the influence of a transversal flow deflector on the cooling of a heated block mounted on a flat plate.The deflector is inclined and therefore it guides the air flow to the upper surface of the block.This configuration is simulating the air-cooling of a rectangular integrated circuit or a current converter mounted on an electronic card.The electronic component is assumed dissipating low heat power,as such,air forced convection is still a sufficient cooling way even without fan or heat sink on the component.The measurements are given by hot and cold wires anemometers and by an InfraRed camera.The results give details of the effects of the deflection on the hydrodynamic and the thermal fields on and over the block for different inclination angles.They show that the deviation caused by the deflector may significantly enhance the heat transfer from the component.Deflection is also able to avoid local overheating of the electronic component.Optimum heat transfer rate and homogenised temperature are shown to be obtained with an inclination angle =30°.