The macro modeling and the solution of traffic flow with road width were investigated.Firstly,a new macro model with the consideration of road width was proposed.Secondly,the effects of road width on uniform flow and ...The macro modeling and the solution of traffic flow with road width were investigated.Firstly,a new macro model with the consideration of road width was proposed.Secondly,the effects of road width on uniform flow and small perturbation were studied.The analytical and numerical results show that widening (shrinking) road can enhance (reduce) the equilibrium speed and flow,and the increments (decrements) will increase with the absolute value of road width gradient.In addition,the numerical results illustrate that the new model can describe the effects of road width on the evolutions of uniform flow and small perturbation.展开更多
AIM: To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. METHODS: E2F5 expression was analyzed in 120 primary HCCs and 29 norm...AIM: To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. METHODS: E2F5 expression was analyzed in 120 primary HCCs and 29 normal liver tissues by immunohistochemistry analysis. E2F5-small interfering RNA was transfected into HepG2, an E2F5-overexpressed HCC cell line. After E2F5 knockdown, cell growth capacity and migrating potential were examined. RESULTS: E2F5 was significantly overexpressed in primary HCCs compared with normal liver tissues (P = 0.008). The E2F5-silenced cells showed significantly reduced proliferation (P = 0.004). On the colony formation and soft agar assays, the number of colonies was significantly reduced in E2F5-silenced cells (P = 0.004 and P = 0.009, respectively). E2F5 knockdown resulted in the accumulation of G0/G1 phase cells and a reduction of S phase cells. The number of migrating/invading cells was also reduced after E2F5 knockdown (P = 0.021). CONCLUSION: To our knowledge, this is the first evidence that E2F5 is commonly overexpressed in primary HCC and that E2F5 knockdown significantly repressed the growth of HCC cells.展开更多
In order to avoid severe performance degradation led by the inter-cell interference (ICI) in orthogonal frequency division multiple access (OFDMA) systems with a frequency reused factor (FRF) of 1,distributed schedule...In order to avoid severe performance degradation led by the inter-cell interference (ICI) in orthogonal frequency division multiple access (OFDMA) systems with a frequency reused factor (FRF) of 1,distributed schedule algorithm (DS-OCS) and distributed proportional fairness schedule algorithm (DPFS-OCS) based on orthogonal complement space (OCS) were proposed. The first right and left singular vectors of the channel that the user experienced were selected as the transmitting and receiving beamforming vectors. An interference space was spanned by the left singular vectors of the entire interference users in the same channel. The most suitable user lay in the OCS of the interference space was scheduled to avoid suffering interference from neighboring cells based on the criterion of system capacity maximizing and proportional fairness. The simulation results show that the average system capacity can be improved by 2%-4% compared with the DS-OCS algorithm with the Max C/I algorithm,by 6%-10% compared with the DPFS-OCS algorithm with the PF algorithm.展开更多
基金Project(NCET-08-0038) supported by the Program for New Century Excellent Talents in Chinese UniversityProjects(70701002,70971007 and 70521001) supported by the National Natural Science Foundation of ChinaProject(2006CB705503) supported by the National Basic Research Program of China
文摘The macro modeling and the solution of traffic flow with road width were investigated.Firstly,a new macro model with the consideration of road width was proposed.Secondly,the effects of road width on uniform flow and small perturbation were studied.The analytical and numerical results show that widening (shrinking) road can enhance (reduce) the equilibrium speed and flow,and the increments (decrements) will increase with the absolute value of road width gradient.In addition,the numerical results illustrate that the new model can describe the effects of road width on the evolutions of uniform flow and small perturbation.
基金Supported by A grant of the Korea Healthcare technology R&D Project, Ministry of Health and Welfare, Republic of Korea (A092258)FG08-11-06 of the 21C Frontier Functional Human Genome Project from the Ministry of Education, Science and Technology
文摘AIM: To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. METHODS: E2F5 expression was analyzed in 120 primary HCCs and 29 normal liver tissues by immunohistochemistry analysis. E2F5-small interfering RNA was transfected into HepG2, an E2F5-overexpressed HCC cell line. After E2F5 knockdown, cell growth capacity and migrating potential were examined. RESULTS: E2F5 was significantly overexpressed in primary HCCs compared with normal liver tissues (P = 0.008). The E2F5-silenced cells showed significantly reduced proliferation (P = 0.004). On the colony formation and soft agar assays, the number of colonies was significantly reduced in E2F5-silenced cells (P = 0.004 and P = 0.009, respectively). E2F5 knockdown resulted in the accumulation of G0/G1 phase cells and a reduction of S phase cells. The number of migrating/invading cells was also reduced after E2F5 knockdown (P = 0.021). CONCLUSION: To our knowledge, this is the first evidence that E2F5 is commonly overexpressed in primary HCC and that E2F5 knockdown significantly repressed the growth of HCC cells.
基金Projects(2009ZX03003-003, 2009ZX03003-004) supported by the Major National Science & Technology ProgramProject(B08038) supported by the "111" Project+1 种基金Project(HX0109012417) supported by Huawei Technologies Co., Ltd, ChinaProject(IRT0852) supported by Program for Changjiang Scholars and Innovative Research Team in Chinese University
文摘In order to avoid severe performance degradation led by the inter-cell interference (ICI) in orthogonal frequency division multiple access (OFDMA) systems with a frequency reused factor (FRF) of 1,distributed schedule algorithm (DS-OCS) and distributed proportional fairness schedule algorithm (DPFS-OCS) based on orthogonal complement space (OCS) were proposed. The first right and left singular vectors of the channel that the user experienced were selected as the transmitting and receiving beamforming vectors. An interference space was spanned by the left singular vectors of the entire interference users in the same channel. The most suitable user lay in the OCS of the interference space was scheduled to avoid suffering interference from neighboring cells based on the criterion of system capacity maximizing and proportional fairness. The simulation results show that the average system capacity can be improved by 2%-4% compared with the DS-OCS algorithm with the Max C/I algorithm,by 6%-10% compared with the DPFS-OCS algorithm with the PF algorithm.
