Objective To investigate the inhibition of low dose radiation （LDR） on S180 sarcomas and its modulation of MMP-2 and TIMP-2 in mice. Methods $180 subcutaneously implanted tumor model mice were randomly divided into ...Objective To investigate the inhibition of low dose radiation （LDR） on S180 sarcomas and its modulation of MMP-2 and TIMP-2 in mice. Methods $180 subcutaneously implanted tumor model mice were randomly divided into two groups： control （N） and low dose radiation （LDR） groups. N mice were sacrificed after 12 h, whereas LDR mice were sacrificed after 12 （LDR-12 h）, 24 （LDR-24 h）, 48 （LDR-48 h）, and 72 （LDR-72 h） h. Thereafter, we measured the tumor volumes. Histopathology was performed, and P-V immunohistochemistry was applied to assess MMP-2 and TIMP-2 expression. Results Compared with the control group, the tumor growth was significantly inhibited in the LDR groups （P 〈 0.05）. MMP-2 expression was considerably reduced in LDR-24h （P 〈 0.05） and LDR-48h （P 〈 0.05）, whereas the change of TIMP-2 was not obvious in the LDR groups （P 〉 0.05） in contrast to that of the control group. Conclusion LDR can effectively suppress the growth of S180 implanted tumors by reducing MMP-2, which is associated with invasion and metastasis.展开更多
The paper presents a study on the effects of low intensity laser irradiation on morphological changes in plants sprouted from maize hybrid seeds （two hybrids） and wheat seeds. Pre-sowing laser irradiation treatment ...The paper presents a study on the effects of low intensity laser irradiation on morphological changes in plants sprouted from maize hybrid seeds （two hybrids） and wheat seeds. Pre-sowing laser irradiation treatment on the seeds was done, intervals from 10 s to 15 min （approximately）, by using a diode laser output power of 12 mW at 904 nm wavelength or with He-Ne laser with output power of 50 mW and 632.8 nm wavelength. Before irradiation seeds were divided into groups （wet and dry, and then in subgroups-irradiated or control groups）. We used maize hybrids, Amilacea and Identata and wheat （Triticum aestivum）. The reflection coefficient in visible range was done for maize varieties. Obtained data show the influence of laser beam to better plant growth. Better results are obtained for dry seed irradiation than for wet. In order to investigate the effect of laser beam and in general to clarify a lot of unsolved photo processes related to bioorganisms at macroscopic and microscopic levels, some optical constants of selected plant families were researched. At the same time, the influence of laser beams of common wavelengths to the selected plants was monitored. Morphological processes of plants （seeds and leaves） irradiated under different conditions and plant growing dynamics were contemplated. The definite correlation analyses of obtained results were made, clearly speaking about the influence of small-dose radiation to characteristics （quantitative and other genetic, bio-stimulating effects） of future plant growth.展开更多
文摘Objective To investigate the inhibition of low dose radiation （LDR） on S180 sarcomas and its modulation of MMP-2 and TIMP-2 in mice. Methods $180 subcutaneously implanted tumor model mice were randomly divided into two groups： control （N） and low dose radiation （LDR） groups. N mice were sacrificed after 12 h, whereas LDR mice were sacrificed after 12 （LDR-12 h）, 24 （LDR-24 h）, 48 （LDR-48 h）, and 72 （LDR-72 h） h. Thereafter, we measured the tumor volumes. Histopathology was performed, and P-V immunohistochemistry was applied to assess MMP-2 and TIMP-2 expression. Results Compared with the control group, the tumor growth was significantly inhibited in the LDR groups （P 〈 0.05）. MMP-2 expression was considerably reduced in LDR-24h （P 〈 0.05） and LDR-48h （P 〈 0.05）, whereas the change of TIMP-2 was not obvious in the LDR groups （P 〉 0.05） in contrast to that of the control group. Conclusion LDR can effectively suppress the growth of S180 implanted tumors by reducing MMP-2, which is associated with invasion and metastasis.
文摘The paper presents a study on the effects of low intensity laser irradiation on morphological changes in plants sprouted from maize hybrid seeds （two hybrids） and wheat seeds. Pre-sowing laser irradiation treatment on the seeds was done, intervals from 10 s to 15 min （approximately）, by using a diode laser output power of 12 mW at 904 nm wavelength or with He-Ne laser with output power of 50 mW and 632.8 nm wavelength. Before irradiation seeds were divided into groups （wet and dry, and then in subgroups-irradiated or control groups）. We used maize hybrids, Amilacea and Identata and wheat （Triticum aestivum）. The reflection coefficient in visible range was done for maize varieties. Obtained data show the influence of laser beam to better plant growth. Better results are obtained for dry seed irradiation than for wet. In order to investigate the effect of laser beam and in general to clarify a lot of unsolved photo processes related to bioorganisms at macroscopic and microscopic levels, some optical constants of selected plant families were researched. At the same time, the influence of laser beams of common wavelengths to the selected plants was monitored. Morphological processes of plants （seeds and leaves） irradiated under different conditions and plant growing dynamics were contemplated. The definite correlation analyses of obtained results were made, clearly speaking about the influence of small-dose radiation to characteristics （quantitative and other genetic, bio-stimulating effects） of future plant growth.
