Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In thi...Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In this paper, we design interplanetary trajectory for main belt asteroid exploration mission with the Mars gravity-assist (MGA) using “pork chop” plots and patched-conic theory and give some initial valuable trajectory parameters on main belt asteroid exploration mission with MGA.展开更多
Cyano substitution has been established as a viable approach to optimize the performance of all-small-molecule organic solar cells.However,the effect of cyano substitution on the dynamics of photo-charge generation re...Cyano substitution has been established as a viable approach to optimize the performance of all-small-molecule organic solar cells.However,the effect of cyano substitution on the dynamics of photo-charge generation remains largely unexplored.Here,we report an ultrafast spectroscopic study showing that electron transfer is markedly promoted by enhanced intermolecular charge-transfer interaction in all-small-molecule blends with cyanided donors.The delocalized excitations,arising from intermolecular interaction in the moiety of cyano-substituted donor,undergo ultrafast electron transfer with a lifetime of∼3 ps in the blend.In contrast,some locally excited states,surviving in the film of donor without cyano substitution,are not actively involved in the charge separation.These findings well explain the performance improvement of devices with cyanided donors,suggesting that manipulating intermolecular interaction is an efficient strategy for device optimization.展开更多
Henoch-Schonlein purpura （HSP） is an IgA-mediated vasculitis which is easy to relapse. A lot of patients have to useglucocorticoids, immunosuppressive drugs and other drugs which will bring sorts of serious side eff...Henoch-Schonlein purpura （HSP） is an IgA-mediated vasculitis which is easy to relapse. A lot of patients have to useglucocorticoids, immunosuppressive drugs and other drugs which will bring sorts of serious side effects. Unfortunately,most of patients have to face the hurt of abdominal pain, arthritis, purpuric rash and renal involvement again after relapse.We have used Xiaochaihu decoration which is a famous formula in Shanghanlun to cure most of patients, especially whowith abdominal pain and purpuric rash. Due to the fact that this formula belongs to the Shaoyang Channels, interestingly,we find that these symptoms are located in regions close to the Shaoyang Channels. So that is the reason why Xiaochaihu decoration could work.展开更多
Objective： To evaluate the relation between argyrophilic nucleolar organizer region （AgNOR）-associated proteins and clinicopathological parameters and survival in non-small-cell lung cancer （NSCLC）. Methods： A t...Objective： To evaluate the relation between argyrophilic nucleolar organizer region （AgNOR）-associated proteins and clinicopathological parameters and survival in non-small-cell lung cancer （NSCLC）. Methods： A total of 207 surgical specimens diagnosed as NSCLC were included in this study. Double-staining procedures were performed using antigen Ki-67 （clone MIB-1） and silver nitrate by immunohistochemical and AgNOR-staining methods. Results： The AgNOR area in MIB-l-positive cells of NSCLC is related to clinicopathological parameters under the TNM （tumor, node, and metastasis） system. The survival of patients with small AgNOR area in MIB-1-positive cells is better than that of patients with large AgNOR area. Molecular, biological （AgNOR area in MIB-l-positive cells）, and clinicopathological （greatest tumor dimension, metastases to regional lymph nodes, histology, and differentiation） parameters are independent prognostic factors of NSCLC.Conclusion： The AgNOR area in MIB- 1-positive cells is related to clinicopathological parameters and survival in NSCLC.展开更多
Traditional light bulbs （e.g., incandescent, fluorescent） use too much electricity, convert very little energy into light of sufficient quality and in their production use toxic contaminants. During the last few yea...Traditional light bulbs （e.g., incandescent, fluorescent） use too much electricity, convert very little energy into light of sufficient quality and in their production use toxic contaminants. During the last few years, a new type of light source, LED （light emitting diode） bulb, has gained increasing popularity and its costs are set to plunge even further. LED bulbs offer many advantages over traditional sources, and they can be used as a direct replacement to existing lighting. This paper will use a spreadsheet-based analysis with hourly solar data supplied by Ecotect to show that, the efficiency of LED installations can be increased when used in conjunction with photovoltaic modules, as the two generate （and use） DC （direct-current） electricity, thereby eliminating intermediate-level losses in the electronic circuitry. If a storage battery is included, the solar panels generate electricity during the times when the occupants are not necessarily using the lighting, but the stored electricity can be used to power the lighting when the energy is required. The latest results demonstrate that, a slight reduction in the required floor area to be lit allows the solar-battery-LED system to be implemented in small buildings using a storage battery size that is within the range of present commercial devices.展开更多
In this study, three-phase satellite images were used to define rules for the allocation of time and space in construction land resources based on a complex adaptive system and game theory. The decision behavior and r...In this study, three-phase satellite images were used to define rules for the allocation of time and space in construction land resources based on a complex adaptive system and game theory. The decision behavior and rules of government agent, enterprise agent and resident agent in construction land growth were explored. A distinctive and dynamic simulation model of construction land growth was built, which integrated multi-agent, GIS technology and RS data and described the interaction among influencing agents, Taking Fuyang City in the Changjiang River Delta as an example, an assessment process for the remote sensing data in construction land and scenario planning was constructed. Repast and ArcGIS were used as simulation platforms. A simulation of the spatial pattern in land-use planning and the setting of scenario planning were conducted by using the incomplete active game, which was based on different natural, social and economic levels. Through this model, a simulation of urban planning space and decision-making for Fuyang City was created. Relevant non-structured problems arising from urban planning management could be identified, and the process and logic of urban planning spatial decision-making could thus be improved. Cell-by-cell comparison showed that the simulation accuracy was over 72%. This model has great potential for use by government and town planners in decision support and technique support in the policy-making process.展开更多
The paper presents an experimental study on the heat transfer and flow friction characteristics in a solar air heater channel fitted with delta-winglet type vortex generators （DWs）. The experiments are conducted by ...The paper presents an experimental study on the heat transfer and flow friction characteristics in a solar air heater channel fitted with delta-winglet type vortex generators （DWs）. The experiments are conducted by varying the airflow rate for Reynolds number in the range of 5000 to 24000 in the test section with a uniform heat-flux applied on the upper channel wall. Firstly, the DW pairs are mounted only at the entrance of the lower wall of the test channel （called DW-E） to create multiple vortex flows at the entry. The effect of two transverse pitches （Re= Pt/H= 1 and 2） at three attack angles （a= 30°, 45° and 60°） of the DW-E with its relative height, b/H= 0.5 （half height of channel） is examined. Secondly, the 30° DWs with three different relative heights （blH = 0.3, 0.4 and 0.5） are placed on the upper wall only （absorber plate, called DW-A） of the test channel. The experimental result reveals that in the first case, the 60° DW-E at Rp = 1 provides the highest heat transfer and friction factor while the 30° DW-E at Rp = 1 performs overall better than the others. In the second case, the 30° DW-A at b/H= 0.5 yields the highest heat transfer and friction factor but the best thermal performance is found at b/H = 0.4.展开更多
Objective:The aim of our study was to evaluate the serum levels of CA19-9 in patients with non-small cell lung cancer(NSCLC)and to analyze the relationship between serum levels of CA19-9 and metastasis.Methods:Serum l...Objective:The aim of our study was to evaluate the serum levels of CA19-9 in patients with non-small cell lung cancer(NSCLC)and to analyze the relationship between serum levels of CA19-9 and metastasis.Methods:Serum levels of CA19-9 in 1200 NSCLC patients from February 2006 to August 2011 were evaluated retrospectively.The relationship between serum levels of CA19-9 and sites of metastasis were analyzed.Results:Of the 1200 patients,528 were stage IV and the positive rate of CA19-9 was 32%(169 cases)and 288 stage III,positive rate 20%(58 cases);144 stage II,positive rate 12%(17 cases);240 stage I,positive rate 3%(7 cases).There were statistical differences from stage I to stage IV(P<0.01).The total positive rate in the 1200 cases was 21%.Furthermore,of the 528 stage IV cases,350 had bone metastasis and the positive rate of CA19-9 was 43%(150 cases)in bone metastatic cases.In turn,in CA19-9 positive patients(169 cases)of stage IV, the positive rate of bone metastasis was 89%(150/169).There was no statistical difference of positive rate of CA19-9 between adenocarcinoma and squamous carcinoma(P>0.05).Conclusion:Positive rate of CA19-9 increases accordingly from stage I to stage IV.The serum levels of CA19-9 may be as an indicator for metastases in patients with NSCLC,especially for bone metastasis in stage IV diseases.展开更多
Objective The correlation between various formative conditions and the pore characterizationsof the anodic alumina membrane is investigated to seek the optimal conditions for the formation of anodic aluminamembrane. M...Objective The correlation between various formative conditions and the pore characterizationsof the anodic alumina membrane is investigated to seek the optimal conditions for the formation of anodic aluminamembrane. Methods High purity aluminum foils are used as the starting materials. The anodization is conduc-ted in three types of electrolytes, 3% sulfuric acid, 5% sulfuric acid and 2. 7% oxalic acid, respectively, with dif-ferent voltages at for 48h. The characterizations of the pore size, the effective porosity and the pore porosity areobserved and determined by scanning electron microscopy. The hydraulic conductances of the membranes are meas-ured to confirm that the pores are open and evaluate the permselectivity of the membranes. Results The experi-mental result shows that the ordered pore arrays are obtained for oxidation under our experimental conditions. Withthe increasing of the voltage, the pore size and pore porosity increased significantly (P <0.05) , while the effectiveporosity decreased significantly (P <0.05) with the same electrolyte. The pore size formed in 3% sulfuric acid or5% sulfuric acid is much smaller than in 2. 7% oxalic acid as an electrolyte. The hydraulic conductance of anodicalumina membrane that formed under our experimental condition is higher than those of the membranes are availablecurrently used in clinical. Conclusion The results suggest that the optimal conditions for the formation of anodicalumina membrane that used in hemodialysis are in 3% or 5% sulfuric acid with 12. 5V to 17. 5V at for 48h.展开更多
In the present study, the data for population dynamics of micromammalia in Dnipropetrovs＇k Region in 1957-1999 and Dnipro-Orel＇s Natural Reserve at 1991-2009 are adduced. With the purpose to drawing up of the long-t...In the present study, the data for population dynamics of micromammalia in Dnipropetrovs＇k Region in 1957-1999 and Dnipro-Orel＇s Natural Reserve at 1991-2009 are adduced. With the purpose to drawing up of the long-term forecast at number are analyzed long-term lines of number on background kind＇s fine micromammals of dominant group. The analysis of long standing rows of number small mammals and comparison data with Wolf number were demonstration, which indicate that dynamic of number phone species （and dominant in particular） carry a cyclic character and contact with 11-year cycles of sun activity. Consequently, it was clearing up hidden periodical in dynamic of number mouse rodents. By that observation was dependence from cycles of sun activity. Probably, that in 2012 year, before peak of sun activity in 2013, next high increase about the number of small mammals for maxima （＂outbreak＂ mass reproduction is a peak ＂big wave＂） will take place.展开更多
According to Zhongjing Zhang's academic thought,gynecological diseases mostly result from deficiency,accumulated cold,and qi stagnation,so the treatment of gynecological miscellaneous diseases should take qi and b...According to Zhongjing Zhang's academic thought,gynecological diseases mostly result from deficiency,accumulated cold,and qi stagnation,so the treatment of gynecological miscellaneous diseases should take qi and blood as the general principle,and focus on the liver.The pathogenesis of mammary glands hyperplasia(MGH)is liver and kidney deficiency,disharmony of the thoroughfare vessel and the conception vessel,the causes of which are emotional imbalance,liver qi depression,and failure of transportation due to spleen deficiency.The superficial causes include qi stagnation,phlegm coagulation,and blood stasis,which are mainly related to the liver,spleen,kidney,the thoroughfare vessel,and the conception vessel.In clinical treatment of MGH,Xiaochaihu Decoction or Sini Powder can be used for qi stagnation syndrome,Xiao Xianxiong Decoction for phlegm coagulation syndrome,Guizhi Fuling Pill or Dahuang Zhechong Pill for spleen deficiency syndrome,and Wenjing Decoction for the deficiency-cold syndrome.展开更多
文摘Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In this paper, we design interplanetary trajectory for main belt asteroid exploration mission with the Mars gravity-assist (MGA) using “pork chop” plots and patched-conic theory and give some initial valuable trajectory parameters on main belt asteroid exploration mission with MGA.
基金supported by the National Key R&D Program of China(No.2018YFA0209100 and No.2017YFA0303703)the National Natural Science Foundation of China(No.21922302,No.21873047,No.91850105,and No.91833305)+1 种基金the Fundamental Research Funds for the Central Universities(No.020414380126)Chun-feng Zhang acknowledges financial support from the Tang Scholar Program。
文摘Cyano substitution has been established as a viable approach to optimize the performance of all-small-molecule organic solar cells.However,the effect of cyano substitution on the dynamics of photo-charge generation remains largely unexplored.Here,we report an ultrafast spectroscopic study showing that electron transfer is markedly promoted by enhanced intermolecular charge-transfer interaction in all-small-molecule blends with cyanided donors.The delocalized excitations,arising from intermolecular interaction in the moiety of cyano-substituted donor,undergo ultrafast electron transfer with a lifetime of∼3 ps in the blend.In contrast,some locally excited states,surviving in the film of donor without cyano substitution,are not actively involved in the charge separation.These findings well explain the performance improvement of devices with cyanided donors,suggesting that manipulating intermolecular interaction is an efficient strategy for device optimization.
基金This study was supported by the National Natural Science Foundation of China （No. 81202839）, the NationalNatural Science Foundation of China （No. 81774080）, the Natural Science Foundation of Shandong Province（ZR2012HQ023）,the Medical science and technology development Foundation of Shandong Province, China （No.2014WS0431）, the Jinan young star of science and technology plan （No. 201406012）, and the Affiliated Hospital ofShandong University of Traditional Chinese Medicine and Shandong University, China.
文摘Henoch-Schonlein purpura （HSP） is an IgA-mediated vasculitis which is easy to relapse. A lot of patients have to useglucocorticoids, immunosuppressive drugs and other drugs which will bring sorts of serious side effects. Unfortunately,most of patients have to face the hurt of abdominal pain, arthritis, purpuric rash and renal involvement again after relapse.We have used Xiaochaihu decoration which is a famous formula in Shanghanlun to cure most of patients, especially whowith abdominal pain and purpuric rash. Due to the fact that this formula belongs to the Shaoyang Channels, interestingly,we find that these symptoms are located in regions close to the Shaoyang Channels. So that is the reason why Xiaochaihu decoration could work.
文摘Objective： To evaluate the relation between argyrophilic nucleolar organizer region （AgNOR）-associated proteins and clinicopathological parameters and survival in non-small-cell lung cancer （NSCLC）. Methods： A total of 207 surgical specimens diagnosed as NSCLC were included in this study. Double-staining procedures were performed using antigen Ki-67 （clone MIB-1） and silver nitrate by immunohistochemical and AgNOR-staining methods. Results： The AgNOR area in MIB-l-positive cells of NSCLC is related to clinicopathological parameters under the TNM （tumor, node, and metastasis） system. The survival of patients with small AgNOR area in MIB-1-positive cells is better than that of patients with large AgNOR area. Molecular, biological （AgNOR area in MIB-l-positive cells）, and clinicopathological （greatest tumor dimension, metastases to regional lymph nodes, histology, and differentiation） parameters are independent prognostic factors of NSCLC.Conclusion： The AgNOR area in MIB- 1-positive cells is related to clinicopathological parameters and survival in NSCLC.
文摘Traditional light bulbs （e.g., incandescent, fluorescent） use too much electricity, convert very little energy into light of sufficient quality and in their production use toxic contaminants. During the last few years, a new type of light source, LED （light emitting diode） bulb, has gained increasing popularity and its costs are set to plunge even further. LED bulbs offer many advantages over traditional sources, and they can be used as a direct replacement to existing lighting. This paper will use a spreadsheet-based analysis with hourly solar data supplied by Ecotect to show that, the efficiency of LED installations can be increased when used in conjunction with photovoltaic modules, as the two generate （and use） DC （direct-current） electricity, thereby eliminating intermediate-level losses in the electronic circuitry. If a storage battery is included, the solar panels generate electricity during the times when the occupants are not necessarily using the lighting, but the stored electricity can be used to power the lighting when the energy is required. The latest results demonstrate that, a slight reduction in the required floor area to be lit allows the solar-battery-LED system to be implemented in small buildings using a storage battery size that is within the range of present commercial devices.
基金Under the auspices of National Science and Technology Support Program of China(No.2012BAH29B04-00)
文摘In this study, three-phase satellite images were used to define rules for the allocation of time and space in construction land resources based on a complex adaptive system and game theory. The decision behavior and rules of government agent, enterprise agent and resident agent in construction land growth were explored. A distinctive and dynamic simulation model of construction land growth was built, which integrated multi-agent, GIS technology and RS data and described the interaction among influencing agents, Taking Fuyang City in the Changjiang River Delta as an example, an assessment process for the remote sensing data in construction land and scenario planning was constructed. Repast and ArcGIS were used as simulation platforms. A simulation of the spatial pattern in land-use planning and the setting of scenario planning were conducted by using the incomplete active game, which was based on different natural, social and economic levels. Through this model, a simulation of urban planning space and decision-making for Fuyang City was created. Relevant non-structured problems arising from urban planning management could be identified, and the process and logic of urban planning spatial decision-making could thus be improved. Cell-by-cell comparison showed that the simulation accuracy was over 72%. This model has great potential for use by government and town planners in decision support and technique support in the policy-making process.
文摘The paper presents an experimental study on the heat transfer and flow friction characteristics in a solar air heater channel fitted with delta-winglet type vortex generators （DWs）. The experiments are conducted by varying the airflow rate for Reynolds number in the range of 5000 to 24000 in the test section with a uniform heat-flux applied on the upper channel wall. Firstly, the DW pairs are mounted only at the entrance of the lower wall of the test channel （called DW-E） to create multiple vortex flows at the entry. The effect of two transverse pitches （Re= Pt/H= 1 and 2） at three attack angles （a= 30°, 45° and 60°） of the DW-E with its relative height, b/H= 0.5 （half height of channel） is examined. Secondly, the 30° DWs with three different relative heights （blH = 0.3, 0.4 and 0.5） are placed on the upper wall only （absorber plate, called DW-A） of the test channel. The experimental result reveals that in the first case, the 60° DW-E at Rp = 1 provides the highest heat transfer and friction factor while the 30° DW-E at Rp = 1 performs overall better than the others. In the second case, the 30° DW-A at b/H= 0.5 yields the highest heat transfer and friction factor but the best thermal performance is found at b/H = 0.4.
文摘Objective:The aim of our study was to evaluate the serum levels of CA19-9 in patients with non-small cell lung cancer(NSCLC)and to analyze the relationship between serum levels of CA19-9 and metastasis.Methods:Serum levels of CA19-9 in 1200 NSCLC patients from February 2006 to August 2011 were evaluated retrospectively.The relationship between serum levels of CA19-9 and sites of metastasis were analyzed.Results:Of the 1200 patients,528 were stage IV and the positive rate of CA19-9 was 32%(169 cases)and 288 stage III,positive rate 20%(58 cases);144 stage II,positive rate 12%(17 cases);240 stage I,positive rate 3%(7 cases).There were statistical differences from stage I to stage IV(P<0.01).The total positive rate in the 1200 cases was 21%.Furthermore,of the 528 stage IV cases,350 had bone metastasis and the positive rate of CA19-9 was 43%(150 cases)in bone metastatic cases.In turn,in CA19-9 positive patients(169 cases)of stage IV, the positive rate of bone metastasis was 89%(150/169).There was no statistical difference of positive rate of CA19-9 between adenocarcinoma and squamous carcinoma(P>0.05).Conclusion:Positive rate of CA19-9 increases accordingly from stage I to stage IV.The serum levels of CA19-9 may be as an indicator for metastases in patients with NSCLC,especially for bone metastasis in stage IV diseases.
文摘Objective The correlation between various formative conditions and the pore characterizationsof the anodic alumina membrane is investigated to seek the optimal conditions for the formation of anodic aluminamembrane. Methods High purity aluminum foils are used as the starting materials. The anodization is conduc-ted in three types of electrolytes, 3% sulfuric acid, 5% sulfuric acid and 2. 7% oxalic acid, respectively, with dif-ferent voltages at for 48h. The characterizations of the pore size, the effective porosity and the pore porosity areobserved and determined by scanning electron microscopy. The hydraulic conductances of the membranes are meas-ured to confirm that the pores are open and evaluate the permselectivity of the membranes. Results The experi-mental result shows that the ordered pore arrays are obtained for oxidation under our experimental conditions. Withthe increasing of the voltage, the pore size and pore porosity increased significantly (P <0.05) , while the effectiveporosity decreased significantly (P <0.05) with the same electrolyte. The pore size formed in 3% sulfuric acid or5% sulfuric acid is much smaller than in 2. 7% oxalic acid as an electrolyte. The hydraulic conductance of anodicalumina membrane that formed under our experimental condition is higher than those of the membranes are availablecurrently used in clinical. Conclusion The results suggest that the optimal conditions for the formation of anodicalumina membrane that used in hemodialysis are in 3% or 5% sulfuric acid with 12. 5V to 17. 5V at for 48h.
文摘In the present study, the data for population dynamics of micromammalia in Dnipropetrovs＇k Region in 1957-1999 and Dnipro-Orel＇s Natural Reserve at 1991-2009 are adduced. With the purpose to drawing up of the long-term forecast at number are analyzed long-term lines of number on background kind＇s fine micromammals of dominant group. The analysis of long standing rows of number small mammals and comparison data with Wolf number were demonstration, which indicate that dynamic of number phone species （and dominant in particular） carry a cyclic character and contact with 11-year cycles of sun activity. Consequently, it was clearing up hidden periodical in dynamic of number mouse rodents. By that observation was dependence from cycles of sun activity. Probably, that in 2012 year, before peak of sun activity in 2013, next high increase about the number of small mammals for maxima （＂outbreak＂ mass reproduction is a peak ＂big wave＂） will take place.
基金special project of Traditional Chinese Medicine Research in Henan Province(20-21ZY1008).
文摘According to Zhongjing Zhang's academic thought,gynecological diseases mostly result from deficiency,accumulated cold,and qi stagnation,so the treatment of gynecological miscellaneous diseases should take qi and blood as the general principle,and focus on the liver.The pathogenesis of mammary glands hyperplasia(MGH)is liver and kidney deficiency,disharmony of the thoroughfare vessel and the conception vessel,the causes of which are emotional imbalance,liver qi depression,and failure of transportation due to spleen deficiency.The superficial causes include qi stagnation,phlegm coagulation,and blood stasis,which are mainly related to the liver,spleen,kidney,the thoroughfare vessel,and the conception vessel.In clinical treatment of MGH,Xiaochaihu Decoction or Sini Powder can be used for qi stagnation syndrome,Xiao Xianxiong Decoction for phlegm coagulation syndrome,Guizhi Fuling Pill or Dahuang Zhechong Pill for spleen deficiency syndrome,and Wenjing Decoction for the deficiency-cold syndrome.
