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少浆血对手术病人血液酸碱平衡的影响
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作者 陈丽君 牛录美 段秀兰 《河北中西医结合杂志》 1999年第2期176-176,共1页
关键词 少浆血 外科手术 酸碱平衡 成分输
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Plasma thrombopoietin levels in patients with aplastic anemia and idiopathic thrombocytopenic purpura 被引量:4
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作者 顾静 陆璐 +1 位作者 徐瑞容 陈秀芳 《Chinese Medical Journal》 SCIE CAS CSCD 2002年第7期983-986,143,共4页
OBJECTIVE: To evaluate the role of thrombopoietin (TPO) in the pathology of chronic thrombocytopenic disease. METHODS: We measured the endogenous plasma concentration of TPO in 40 patients with acquired aplastic anaem... OBJECTIVE: To evaluate the role of thrombopoietin (TPO) in the pathology of chronic thrombocytopenic disease. METHODS: We measured the endogenous plasma concentration of TPO in 40 patients with acquired aplastic anaemia (AA) and in 32 patients with idiopathic thrombocytopenic purpura (ITP) by a sensitive Sandwich enzyme-linked immunosorbent assay (ELISA) and compared the results. RESULTS: Plasma TPO concentrations were significantly higher in AA patients (774 +/- 393 pg/ ml) in comparison with healthy control subjects (55 +/- 34 pg/ml, P 0.05). There was also no relationship between their plasma TPO levels and platelet counts. CONCLUSIONS: TPO levels may be regulated not only by platelets but also by megakaryocytes in AA and ITP, and measurement of TPO levels is useful for diagnosing thrombocytopenia and understanding the pathophysiology of thrombocytopenia. 展开更多
关键词 Adolescent Adult Anemia Aplastic Female Humans Male Middle Aged Purpura Thrombocytopenic Idiopathic RNA Messenger THROMBOPOIETIN
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