优化自制面膜尺涂药法在5-氨基酮戊酸光动力疗法治疗中重度面部痤疮中的应用研究

本研究旨在评估自制面膜尺涂药法在5-氨基酮戊酸光动力疗法(ALA-PDT)治疗中重度面部痤疮的临床效果。方法 选择2021年1月至2022年12月期间柳州市工人医院皮肤科收治的60例中重度面部痤疮患者,随机分为对照组和观察组,每组各30例。两组均接受ALA-PDT治疗,对照组使用5% ALA溶液在皮损处涂抹,观察组则采用自制面膜尺涂药法进行涂抹。对比两组涂药方法的疗效。结果 观察组的总体治疗有效率为96.67%,显著高于对照组的80.00%(P<0.05),显示观察组的治疗效果更佳;观察组在治疗后2周和12周的GACS评分均低于对照组(P<0.05);观察组满意度为100.00%,高于对照组的86.67%(P<0.05)。结论 自制面膜尺涂药法在ALA-PDT治疗中重度面部痤疮方面效果显著,能够改善痤疮严重程度,提高患者满意度。

带蒂筋膜瓣包裹尺神经的肘管扩大成形术联合中医针刺治疗肘管综合征的临床疗效分析

在治疗肘管综合征时,给予带蒂筋膜瓣包裹尺神经的肘管扩大成形术以及中医针刺,并分析该方式的应用效果。方法 病例抽取时间范围介于2021年10月至2023年10月,以60例确诊为肘管综合征患者为观察对象,分组时依据随机原则进行平均划分,共计分为两组,治疗中分别给予尺神经皮下前置术、带蒂筋膜瓣包裹尺神经的肘管扩大成形术联合中医针刺,就此对两组患者所获取的临床疗效进行分析。结果 治疗后观察组肘管综合征功能、ADL评分数据水平更高(P<0.05);接受手术治疗后,SF-36水平更佳状态者为观察组(P<0.05);观察组术期疼痛、血肿形成、肘管内囊肿总和低于对照组(P<0.05);观察组治疗后肘部尺神经传导速度与小指末节指腹两点辨别觉状态更为理想(P<0.05)。结论 临床在面对肘管综合征患者时,可给予带蒂筋膜瓣包裹尺神经的肘管扩大成形术以及中医针刺,该模式的实施有助于保护尺神经,促进尺神经功能的恢复,优化患者生活质量,具有较高临床应用价值。

带筋膜尺神经前移治疗肘管综合征

目的 研究带筋膜尺神经前移在肘管综合征治疗中的作用。方法 采用带筋膜的尺神经前移术治疗 42例 (5 1侧 )肘管综合征。结果 感觉运动评分提高了 40 .3 % ,有效率达 96%。结论 带筋膜尺神经前移治疗肘管综合征有助于保护尺神经的血供及神经分支。

带血供尺神经深筋膜瓣下前置术解剖学研究

目的为带血供尺神经深筋膜瓣下前置术提供解剖学依据。方法在12侧福尔马林固定的成人尸体上肢标本、8侧新鲜尸体上肢标本上观测尺神经在肘部的血供。结果肘部尺神经血供来源有3个:尺侧上副动脉(SUCA)、尺侧下副动脉(IUCA)和尺侧返动脉后支(PURA),与尺神经伴行长度分别约为15.0cm、5.0cm和5.5cm。尺神经于肘部发出关节支和肌支分别为1～3支。结论行尺神经深筋膜瓣下前置术时至少应保留SUCA或IUCA,深筋膜瓣的制作应依据任意皮瓣原则。

可吸收医用膜与尺神经肌膜瓣下前置联用对肘管综合征患者疗效及神经电生理的影响

目的探讨可吸收医用膜与尺神经肌膜瓣下前置联用对肘管综合征患者的疗效及神经电生理的影响。方法选择2016年2月至2018年12月医院诊治的肘管综合征患者84例作为研究对象,通过抽签法将其等分成试验组及对照组,每组42例。对照组予以尺神经肌膜瓣下前置治疗,试验组则于对照组的基础上增用可吸收医用膜治疗,分别评价两组临床疗效、治疗前后神经电生理变化情况、并发症控制效果。结果试验组总有效率高于对照组(P<0.05);治疗后试验组及对照组小指展肌引出CMAP波幅均高于治疗前,且试验组高于对照组(P<0.05);试验组与对照组在切口血肿、切口附近感觉减退、瘢痕增生发生率方面对比差异均无统计学意义(P>0.05)。结论可吸收医用膜与尺神经肌膜瓣下前置联用可显著提高肘管综合征患者的疗效。

尺神经筋膜下前置术与原位减压术治疗中度肘管综合征的临床疗效

目的研究尺神经筋膜下前置术与原位减压术在治疗中度肘管综合征的临床效果。方法收集收治的中度肘管综合征55例患者资料,分为2组,筋膜下前置组30例,原位减压组25例。分别行尺神经筋膜下前置术和原位减压术,对比2组术式患者术后的疗效。结果手术时间以及切口长度原位减压组短于筋膜下前置组(P<0.05);筋膜下前置组与单纯减压组术后的优良率比较差异无统计学意义(P>0.05);2组患者住院时间及术后并发症的发生率对比差异无统计学意义(P>0.05)。结论中度肘管综合征采用尺神经筋膜下前置术与尺神经原位减压术术后疗效无差异,但原位减压术操作更简单、术程更短、切口更小。

尺神经血液供应神经前置的解剖学研究

目的研究肘部尺神经的伴行供养血管,尺侧上副动脉灌注尺神经的长度,肘部前内侧深筋膜血供情况,为临床带血供尺神经深筋膜瓣下前置术治疗肘管综合征提供理论支持。方法解剖20具无外伤、无畸形的福尔马林防腐固定成人尸体手标本及5具无外伤、无畸形的成人新鲜尸体,对肘管结构进行观察,观察肘部尺神经分支及其血供,测量对尺神经血液供应的血管与神经伴行长度及垂直距离。并将红色乳胶经新鲜尸体的手标本动脉中灌注,模拟尺神经松解前置术对新鲜标本进行手术操作,测量尺神经可前置的最大距离。深筋膜动脉采肘动脉灌注墨汁和尺神经级织切片的方法观察尺侧上副动脉对尺神经内部血供营养的长度。结果 (1)尺神经外部血供观察:尺神经的营养血管腋部、内侧肌间隔后方、尺神经沟、前臂部主要由尺侧上副动脉、尺侧返动脉后支及尺侧下副动脉供应。三支动脉与尺神经伴行长度分别为15.0cm、5.0cm和5.5cm,起点距肱骨内上髁的距离分别为15.5cm、6.0cm和5.5cm。(2)尺侧上副动脉对尺神经内部血供营养范围:自尺侧上副动脉灌注墨汁后,20例标本中有5侧上肢尺神经由腋部到腕部全长墨染,分别于腕部、手背支、腋部,神经外膜上纵行血管网清晰可见。结论行尺神经深筋膜瓣下前置术时至少应保留尺侧上副动脉或尺侧下副动脉。应依据任意皮瓣原则进行深筋膜瓣的制作。

Proton-exchange Sulfonated Poly（ether ether ketone）/Sulfonated Phenolphthalein Poly（ether sulfone） Blend Membranes in DMFCs

A sulfonated poly（ether ether ketone） （SPEEK） membrane with fairly high degree of sulfonation （DS） swells excessively and even dissolves at high temperature. To solve these problems, sulfonated phenolphthalein poly（ether sulfone） （SPES-C, DS= 53.7%） is blended with the SPEEK matrix （DS= 55.1%, 61.7%） to prepare SPEEKJSPES-C blend membrane. The decrease in swelling degree and methanol permeability of the membrane is dose-dependent. Pure SPEEK （DS = 61.7%） membrane dissolves completely in water at 70℃, whereas the swelling degree of the SPEEK （DS = 61.7%）/SPES-C （40%, by mass） membrane is 29.7% at 80℃. From room temperature to 80℃, the methanol permeability of all SPEEK （DS = 55.1%）/SPES-C blend membranes is about one order of magnitude lower than that of Nafion 115. At higher temperature, the addition of SPES-C polymer increases the dimensional stability and greater proton conductivity can be achieved. The SPEEK （DS = 55.1%）/SPES-C （40%, by mass） membrane can withstand temperatures up to 150℃. The proton conductivity of SPEEK （DS = 55.1%）/SPES-C （30%, by mass） membrane approaches 0.16 S·cm^-1, matching that of Nafion 115 at 140℃ and 100% RH, while pure SPEEK （DS = 55.1%） membrane dissolves at 90℃. The SPEEK/SPES-C blend membranes are promising for use in direct methanol fuel cells because of their good dimensional stability, high proton conductivity, and low methanol permeability.

Modeling investigation of geometric size effect on pervaporation dehydration through scaled-up hollow fiber NaA zeolite membranes

A mass transfer model in consideration of multi-layer resistances through NaA zeolite membrane and lumen pressure drop in the permeate side was developed to describe pervaporation dehydration through scaled-up hollow fiber supported NaA zeolite membrane. It was found that the transfer resistance in the lumen of the permeate side is strongly related with geometric size of hollow fiber zeolite membrane, which could not he neglected. The effect of geometric size on pervaporation dehydration could be more significant under higher vacuum pressure in the permeate side. The transfer resistance in the lumen increases with the hollow fiber length but decreases with lumen diameter. The geometric structure could be optimized in terms of the ratio of lumen diameter to membrane length. A critical value of d1/L （Rc） to achieve high permeation flux was empirically correlated with extraction pressure in the permeate side. Typically, for a hollow fiber supported NaA zeolite membrane with length of 0.40 m, the lumen diameter should be larger than 2.0 mm under the extraction pressure of 1500 Pa.

THEORETICAL EFFECTS OF MOLECULAR DIMENSION AND CONFIGURATION ON EFFECTIVE DIFFUSION COEFFICIENT OF MACROMOLECULES IN MICROPOROUS MEMBRANES

This paper presents a theoretical method for predicting the effective diffusion coefficient of macromolecules in the microporous membrfines in view of the effects of molecular dimension and configuration. On the basis of the hindered diffusion theory of spherical neutral macromolecules in a micropore of a long cylinder, the effects of molecular dimension and configuration are studied by defining two molecular dimensions:the mean projected radius to predict the concentration partition and the ' hydrodynamically equivalent sphere' radius to evaluate the hydrodynamic reverse drag force. The quantitative comparison shows that the effective diffusion coefficients for different macromolecules predicted by the present method are more consistent with the available published experimental data.

Effect of Zn/Mg ratio on cathodic protection of carbon steel using Al-Zn-Mg sacrificial anodes

Al-Zn-Mg alloys with different Zn/Mg mass ratios were evaluated as sacrificial anodes for cathodic protection of carbon steel in 3.5 wt.%Na Cl solution.The anodes were fabricated from pure Al,Zn and Mg metals using casting technique.Optical microscopy,SEM-EDS,XRD and electrochemical techniques were used.The results indicated that with decreasing Zn/Mg mass ratio,the grain size ofα(Al)and the particle size of the precipitates decreased while the volume fraction of the precipitates increased.The anode with Zn/Mg mass ratio>4.0 exhibited the lowest corrosion rate,while the anode with Zn/Mg mass ratio<0.62 gave the highest corrosion rate and provided the highest cathodic protection efficiency for carbon steel(AISI 1018).Furthermore,the results showed that the anode with Zn/Mg mass ratio<0.62 exhibited a porous corrosion product compared to the other anodes.

乳腺癌新辅助化疗的乳房肿物体表定位膜定位

目的探讨乳房肿物体表定位膜（简称乳房尺膜）标记法在乳腺癌新辅助化疗中乳腺肿瘤病灶定位的应用价值。方法对120例乳腺癌患者新辅助化疗前同时采用乳房尺膜对乳腺肿瘤病灶的位置和边界进行标记。对于非隆起性乳腺肿瘤病灶，将尺膜直接贴在乳房上，正向标记；对于边界不清楚的肿瘤病灶在超声引导下确定边界。对于隆起性乳腺肿瘤病灶，尺膜贴在肿瘤病灶以外的正常乳房皮肤上，反向标记。应用TEC方案2个疗程后再次标记，结合超声、钼靶及核磁共振结果综合判断临床疗效，决定手术或改为TP方案继续化疗。术前复位第一次标记结果，按标记的乳腺肿瘤病灶的位置和边界手术。结果完全缓解26例，部分缓解76例，稳定10例，进展8例。其中，完全缓解的24例按尺膜标记的肿瘤病灶位置和边界行保乳手术，部分缓解的18例按尺膜标记的肿瘤病灶位置及残余肿瘤病灶边界外1．5～2．0cm行保乳手术；其余78例，按尺膜标记的肿瘤病灶边界，行简化根治术，其中局部晚期皮缘不充足的13例，采用腹部全厚游离皮瓣覆盖创面。结论乳腺癌新辅助化疗的肿瘤病灶定位应用乳房尺膜法准确且无创，有效节省了肿瘤病灶周围正常的乳腺组织及皮肤，患者依从性好，明显优于传统的坐标法、体表纹身法以及金属标志物法。乳房尺膜标记法操作简单，尺膜价格低廉，便于普及和推广。

Quantum size effects in InP inner film fiber

Based on the semiconductor amplifiing properties and the structure of optical fiber wave guide an InP inner fiber is developed.The InP inner film fiber can be employed as a small size,broadband,and ultra-short fiber amplifier. The quantum size effects of the fiber are emphatically investigated in the work. Using the experimental data,we compare the effective mass approximation （EMA） with effective pararneterization within the tight binding （EPTB） models for the accurate description of the quantum size effects in InP. The results show that the EPTB model provides an excellent description of band gap variation over a wide range of sizes. The Bohr diameter and the effective Rydberg energy of InP are calculated. Finally,the amplifiing properties of the InP inner film fiber are discussed due to the quantum size effects.

Implementation of the Masquelet Technique in Complicated Septic Non-union of the Ulna A Case Report

Abstract： Long bone septic non-union by MRSA （methicillin-resistant Staphylococcus aureus） is always a challenge for the orthopaedic society. Traditional treatment options include distraction osteogenesis methods and vascularised bone grafting. These techniques require a high level of expertise and are frequently involved with a variety of side effects or complications. We present a rare case of ulnar fracture complicated by MRSA infection that led to septic non-union. We treated the septic non union with the technique of induced membrane formation （Masquelet technique）. A 33 year old male presented to the outpatient clinic, 2 months after internal fixation of a Gustillo I fracture of the left forearm. There was pus discharge from the operative wound and specimen culture was positive for MRSA. Initially the patient received conservative treatment with antibiotics for a period of one month. However, the patient returned with the same clinical presentation. The patient was then treated with hardware removal of the ulna and debridement of the septic non-union. The formed 5 cm bone defect was filled with cement spacer and the ulnar bone was fixed with external fixation. Eight weeks later, the spacer was removed and the bone gap was filled with autologous cancellous bone graft from iliac crest. Five months after grafting, the patient was reviewed. No clinical or functional problems were noted and osseous consolidation of the ulnar bone was confirmed in plain x-rays. The Masquelet technique is a promising alternative treatment for the management of infected long bone non-unions of the upper extremity.

The Analysis of Nano-Size Inhomogeneities of Substrate by Surface Electrons over Superfluid Helium Film

The surface quality of the substrate is a crucial factor in building ＂clean＂ quantum-dimensional systems. There are a number of micro-nano metric methods for the analysis state of surface： the atomic force microscopy, the scanning tunneling microscopy and others. The SE （surface electron） over substrate has a ＂soft＂ hydrogen-like spectrum in the normal direction and the SEs mobility along is sensitive to the inhomogeneities of the substrate and this is analyzed in work. The values of electron mobility and energy of thermal activation are basic parameters of transport process which essentially depend on the helium film thickness. For analysis of nano-size inhomogeneities of substrate here we apply a new method providing a uniformity of the film thickness on substrate and fixing of measuring cell with supply wires. The plunger with electro-mechanic driver into a hermetic chamber is used for variation the helium level and consequently the film thickness. Considering values the conductivity and the variation of potential along surface is estimated the effective size of roughness from several nanometers （for non-saturated helium film） to 10^2 nm （for saturated film）.

Dependence of Optical Absorption in Silicon Nanostructures on Size of Silicon Nanoparticles

The amorphous silicon nanoparticles （Si NPs） embedded in silicon nitride （SiNx） films prepared by helicon wave plasma-enhanced chemical vapor deposition （HWP-CVD） technique are studied. From Raman scattering investigation, we determine that the deposited film has the structure of silicon nanocrystals embedded in silicon nitride （nc-Si/SiNx） thin film at a certain hydrogen dilution amount. The analysis of optical absorption spectra implies that the Si NPs is affected by quantum size effects and has the nature of an indirect-band-gap semiconductor. Further, considering the effects of the mean Si NP size and their dispersion on oscillator strength, and quantum-confinement, we obtain an analytical expression for the spectral absorbance of ensemble samples. Gaussian as well as lognormal size-distributions of the Si NPs are considered for optical absorption coefficient calculations. The influence of the particle size-distribution on the optical absorption spectra was systematically studied. We present the fitting of the optical absorption experimental data with our model and discuss the results.

Vibration Response Characteristics against the Radial and Axial Shocks on Small Size Hard Disk Drive Spindle Supported by Oil Film Bearings

This paper describes the experimental study on shock response of FDB （fluid dynamic bearing） spindle for HDDs （hard disk drives）. The FDBs are widely used as rotating shaft support elements for HDD spindle motors. Recently, the opportunity for the HDD spindle motors exposed to external vibration has been increasing because the HDDs are used for various information related equipment such as mobile PCs （personal computers）, video cameras, car navigation systems and so on. Hence, the rotating shaft has a possibility to come in contact with the bearing by external shocks and it causes wear or seizure to the bearing surface. To avoid the problem, it is extremely important to know how the spindle moves against the large shock on HDDs experimentally. However, as far as the authors know, there are few experimental studies treating the shock response of HDD spindles. In this paper, firstly, we propose a new test rig and experimental method for shock response of FDB spindles. Then the shock tests against the radial and axial disturbance on FDB spindle for 2.5＂ HDD are conducted. Finally, the experimental results of shock response waveforms and maximum displacement of disk are shown.

Ultrafast Electron Diffraction with Spatiotemporal Resolution of Atomic Motion

Ultrafast electron diffraction （UED） is a rapidly advancing technique capable of recording the atomic-detail structural dynamics in real time. We report the establishment of the first UED system in China. Employing this UED apparatus, both the coherent and the concurrent thermal lattice motions in an aluminium thin-film, trigged by ultrafast laser heating, have been observed. These results demonstrate its ability to directly measure a sub-milli-angstrom lattice spacing change on a sub-picosecond time scale.