【目的】观察尿三针联合托特罗定治疗膀胱过度活动症的临床疗效及安全性。【方法】将67例膀胱过度活动症患者随机分为治疗组和对照组,其中,对照组33例,给予托特罗定口服;治疗组34例,在对照组治疗的基础上,加用尿三针治疗,取穴为中元、...【目的】观察尿三针联合托特罗定治疗膀胱过度活动症的临床疗效及安全性。【方法】将67例膀胱过度活动症患者随机分为治疗组和对照组,其中,对照组33例,给予托特罗定口服;治疗组34例,在对照组治疗的基础上,加用尿三针治疗,取穴为中元、关元、双侧三阴交。4周为1个疗程,连续治疗3个疗程。治疗12周后,比较2组患者治疗前后膀胱过度活动症症状评分(OABSS)以及生活质量评分(Quality of Life,QOL)的变化情况,并评价2组的安全性及不良反应的发生情况。【结果】(1)治疗4、8、12周后,2组患者的OABSS评分均明显改善(P<0.05),且治疗组在治疗12周后OABSS评分改善明显优于同期对照组,差异有统计学意义(P<0.05)。(2)治疗12周后,2组患者的生活质量评分均明显改善(P<0.05),且治疗组改善明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗组总有效率为97.06%(33/34),对照组为84.85%(28/33)。治疗组疗效优于对照组,差异有统计学意义(P<0.05)。(4)2组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。【结论】尿三针联合托特罗定口服治疗膀胱过度活动症,可明显改善患者的临床症状,提高患者的生活质量,且安全性高,临床疗效显著。展开更多
Objective To determine the effect of needling at Sanyinjiao(SP6)on random blood glucose(RBG)levels and cardiovascular function in patients with type 2 diabetes mellitus(T2DM).Methods In this randomized placebo-control...Objective To determine the effect of needling at Sanyinjiao(SP6)on random blood glucose(RBG)levels and cardiovascular function in patients with type 2 diabetes mellitus(T2DM).Methods In this randomized placebo-controlled study,T2DM patients(aged 35-65 years)were recruited from the Government Yoga and Naturopathy Medical College and Hospital,Chennai,India,between January 5,2022 and March 15,2023.Participants were randomly as-signed to either acupuncture group or sham acupuncture group.The acupuncture group re-ceived bilateral needling at Sanyinjiao(SP6)while sham acupuncture group received needling at a non-acupuncture point[1.5 cun lateral to Sanyinjiao(SP6)]for 30 min.Primary outcome was RBG,and secondary outcomes included systolic blood pressure(SBP),diastolic blood pressure(DBP),pulse rate(PR),pulse pressure(PP),mean arterial pressure(MAP),rate pressure product(RPP),and double product(Do-P).All parameters were assessed imme-diately before and after intervention.Results A total of 100 patients with T2DM were enrolled in the study,and blinded to acupuncture group(n=50)and sham acupuncture group(n=50).Intergroup analysis showed that significant reductions in RBG(P<0.001),SBP(P=0.035),DBP(P=0.008),and MAP(P=0.009)were found in acupuncture group compared with sham acupuncture group.Within-group analysis showed significant reductions in RBG(P<0.001),SBP(P<0.001),DBP(P=0.008),PP(P=0.023),MAP(P<0.001),RPP(P<0.001),and Do-P(P=0.002)in acupunc-ture group,whereas sham acupuncture group showed a significant decrease in PR(P=0.023)only in the post-test assessment compared with pre-test assessment.Conclusion A period of 30 min of needling at the Sanyinjiao(SP6)acupuncture point re-duces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points.Sanyinjiao(SP6)acupuncture may offer an immediate,non-pharmacological intervention to strengthen glycemic control management and cardio-vascular health in T2DM patients.展开更多
文摘【目的】观察尿三针联合托特罗定治疗膀胱过度活动症的临床疗效及安全性。【方法】将67例膀胱过度活动症患者随机分为治疗组和对照组,其中,对照组33例,给予托特罗定口服;治疗组34例,在对照组治疗的基础上,加用尿三针治疗,取穴为中元、关元、双侧三阴交。4周为1个疗程,连续治疗3个疗程。治疗12周后,比较2组患者治疗前后膀胱过度活动症症状评分(OABSS)以及生活质量评分(Quality of Life,QOL)的变化情况,并评价2组的安全性及不良反应的发生情况。【结果】(1)治疗4、8、12周后,2组患者的OABSS评分均明显改善(P<0.05),且治疗组在治疗12周后OABSS评分改善明显优于同期对照组,差异有统计学意义(P<0.05)。(2)治疗12周后,2组患者的生活质量评分均明显改善(P<0.05),且治疗组改善明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗组总有效率为97.06%(33/34),对照组为84.85%(28/33)。治疗组疗效优于对照组,差异有统计学意义(P<0.05)。(4)2组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。【结论】尿三针联合托特罗定口服治疗膀胱过度活动症,可明显改善患者的临床症状,提高患者的生活质量,且安全性高,临床疗效显著。
文摘Objective To determine the effect of needling at Sanyinjiao(SP6)on random blood glucose(RBG)levels and cardiovascular function in patients with type 2 diabetes mellitus(T2DM).Methods In this randomized placebo-controlled study,T2DM patients(aged 35-65 years)were recruited from the Government Yoga and Naturopathy Medical College and Hospital,Chennai,India,between January 5,2022 and March 15,2023.Participants were randomly as-signed to either acupuncture group or sham acupuncture group.The acupuncture group re-ceived bilateral needling at Sanyinjiao(SP6)while sham acupuncture group received needling at a non-acupuncture point[1.5 cun lateral to Sanyinjiao(SP6)]for 30 min.Primary outcome was RBG,and secondary outcomes included systolic blood pressure(SBP),diastolic blood pressure(DBP),pulse rate(PR),pulse pressure(PP),mean arterial pressure(MAP),rate pressure product(RPP),and double product(Do-P).All parameters were assessed imme-diately before and after intervention.Results A total of 100 patients with T2DM were enrolled in the study,and blinded to acupuncture group(n=50)and sham acupuncture group(n=50).Intergroup analysis showed that significant reductions in RBG(P<0.001),SBP(P=0.035),DBP(P=0.008),and MAP(P=0.009)were found in acupuncture group compared with sham acupuncture group.Within-group analysis showed significant reductions in RBG(P<0.001),SBP(P<0.001),DBP(P=0.008),PP(P=0.023),MAP(P<0.001),RPP(P<0.001),and Do-P(P=0.002)in acupunc-ture group,whereas sham acupuncture group showed a significant decrease in PR(P=0.023)only in the post-test assessment compared with pre-test assessment.Conclusion A period of 30 min of needling at the Sanyinjiao(SP6)acupuncture point re-duces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points.Sanyinjiao(SP6)acupuncture may offer an immediate,non-pharmacological intervention to strengthen glycemic control management and cardio-vascular health in T2DM patients.
