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24小时尿蛋白、尿液亚硝酸盐、尿沉渣细菌定量计数诊断肾病综合征合并尿路感染的价值
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作者 杨琦 郭楠 +5 位作者 栗晓斌 李洪敏 武玉鑫 宋天佳 刘尚建 姚兴伟 《浙江医学》 CAS 2024年第23期2521-2526,共6页
目的探讨24小时尿蛋白(24 hUP)、尿液亚硝酸盐、尿沉渣细菌定量计数诊断肾病综合征(NS)合并尿路感染(UTI)的价值。方法回顾性选取2021年10月至2023年10月北京中医药大学东直门医院住院的NS患者380例,根据是否合并UTI分为感染组96例和无... 目的探讨24小时尿蛋白(24 hUP)、尿液亚硝酸盐、尿沉渣细菌定量计数诊断肾病综合征(NS)合并尿路感染(UTI)的价值。方法回顾性选取2021年10月至2023年10月北京中医药大学东直门医院住院的NS患者380例,根据是否合并UTI分为感染组96例和无感染组284例。比较两组患者临床资料、24 hUP、尿液亚硝酸盐及尿沉渣细菌定量计数阳性率,分析24 hUP与尿液亚硝酸盐、尿沉渣细菌定量计数的相关性,比较治疗前后24 hUP、尿液亚硝酸盐及尿沉渣细菌定量计数变化情况,分析24 hUP、尿液亚硝酸盐、尿沉渣细菌定量计数对NS合并UTI的影响及诊断价值。结果感染组年龄、血肌酐(Scr)水平高于无感染组,血清IgG水平低于无感染组(均P<0.05);感染组24 hUP水平、尿液亚硝酸盐阳性率、尿沉渣细菌定量计数阳性率均高于无感染组(均P<0.05);感染组患者24 hUP与尿液亚硝酸盐、尿沉渣细菌定量计数呈正相关(rs=0.577、0.610,均P<0.05);两组患者治疗后24 hUP、尿液亚硝酸盐、尿沉渣的菌定量计数阳性率均低于治疗前(均P<0.05),感染组治疗前、治疗后24 hUP、尿液亚硝酸盐、尿沉渣细菌定量计数阳性率均高于无感染组(均P<0.05);校正后logistic回归分析显示,24 hUP、尿液亚硝酸盐、尿沉渣细菌定量计数均是NS合并UTI的独立影响因素(均P<0.05);24 hUP、尿液亚硝酸盐、尿沉渣细菌定量计数联合诊断NS合并UTI的AUC为0.926(95%CI:0.894~0.950),明显优于各指标单独诊断。结论NS合并UTI患者中24 hUP水平升高与尿液亚硝酸盐、尿沉渣细菌定量计数呈正相关,三者联合检测有助于提高NS合并UTI的诊断率。 展开更多
关键词 肾病综合征 尿路感染 24小时尿蛋白水平 尿液亚硝酸盐 尿沉渣细菌定量计数
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尿常规亚硝酸盐测定与尿沉渣细菌计数对尿路感染的筛查 被引量:9
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作者 钟雪萍 刘静 黄凤珍 《医学信息》 2011年第23期206-207,共2页
目的探讨尿液亚硝酸的测定与尿沉渣细菌计数对尿路感染的筛查。方法以优利特-500B和SysmexUF-1000i全自动尿有形成分分析仪及法国生物梅里埃VITEK 2 COMPACT细菌鉴定/药敏仪对270份中段尿标本分别进行检测并比较。结果对270份中段标... 目的探讨尿液亚硝酸的测定与尿沉渣细菌计数对尿路感染的筛查。方法以优利特-500B和SysmexUF-1000i全自动尿有形成分分析仪及法国生物梅里埃VITEK 2 COMPACT细菌鉴定/药敏仪对270份中段尿标本分别进行检测并比较。结果对270份中段标本检测结果中,亚硝酸盐检测阳性45例,阴性225例,对尿路感染诊断的阳性预测值911%,阴性预测值57.0%。尿沉渣细菌计数阳性142例,阴性128例,对尿路感染诊断的阳性预测值627%,阴性预测值83.6%。结论当亚硝酸盐试验阳性时,结果比较可靠,有很高的尿培养阳性率。对于尿沉渣细菌计数,可利用其阴性预测值较高的特点,对检测结果阴性的标本进行筛除。若能将尿液亚硝酸盐试验与尿沉渣细菌计数联合检测,可在一定水平上对尿路感染有更高的筛查意义。 展开更多
关键词 尿液亚硝酸盐测定 尿沉渣细菌计数 尿细菌培养 尿路感染
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The Comparison of Urinalysis Parameters in Pregnant and Non-pregnant Women in Berat
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作者 Bakaj (Cizmja) Aurora Lika (Cekani) Mirela 《Journal of Life Sciences》 2014年第10期857-860,共4页
Routine chemical examination of urine has changed dramatically since the early days of urine testing, owing to the development of the reagent strip method for chemical analysis. Reagent strips currently provide a simp... Routine chemical examination of urine has changed dramatically since the early days of urine testing, owing to the development of the reagent strip method for chemical analysis. Reagent strips currently provide a simple, rapid means for performing medically significant chemical analysis of urine, including pH, protein, glucose, ketones, blood, bilirubin, urobilinogen, nitrite, leukocytes, and specific gravity. The study was conducted in the Medical Hospital in Berat City. A total of 480 midstream urine specimens were collected in sterile containers from urinalysis cases of women (reproductive age group) from outdoor and indoor female patients (n = 480). A total of 240 pregnant women and 240 non-pregnant women were evaluated. The patients included were between the ages of 15-50 years. The obtained results in this study ware: 1) The percentage of glucose in pregnant women has resulted in 6.67%, while in non-pregnant women 23.34% distributed by age group; 2) 16% of pregnant women had bilirubinuria, where the highest percentage is occupied by 1+, while in non-pregnant women 26%, where the highest percentage is occupied by 1+; 3) Urobilinogen in pregnant women has this distribution: 11.67% of the cases included in the amount of 0.7, 82% of the cases included in the amount of 1 and only 6.34% of the quantity 1.5. Urobilinogen in non-pregnant women: 11.67% of cases are in the amount 0.7 and 72.92% of the quantity 1, while others are scattered. The material was collected in sterile cups for urine. The collected material was processed based on evidence to beakers or microscope preparations. In 5 age groups, the highest percentage is from 26 to 30 years old in the pregnant women and for the non-pregnant women 15 to 20 years old. 展开更多
关键词 GLUCOSE BILIRUBIN urinary pH PROTEIN leukocytes.
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