To evaluate blood concentration of melatonin and urinary excretion of its metabolite, 6-sulfatoxymelatonin （6-OHMS）, in functional dyspepsia （FD）. METHODS： Ninety individuals were enrolled in the study： 30 in ea...To evaluate blood concentration of melatonin and urinary excretion of its metabolite, 6-sulfatoxymelatonin （6-OHMS）, in functional dyspepsia （FD）. METHODS： Ninety individuals were enrolled in the study： 30 in each study group： patients with postprandial distress syndrome （PDS）, epigastric pain syndrome （EPS）, and controls. Blood samples were drawn at 02：00 and 09：00 h and 24-h urine collection was performed. Serum melatonin and urinary 6-OHMS concentrations were measured by enzyme-linked immunosorbent assay. RESULTS： Serum melatonin concentration at night and in the morning was significantly （P 〈 0.001） higher inPDS patients [at 02：00 h-93.3 pg/mL, quartile range （QR）： 79.8-116.2; at 09.00 h-14.3 pg/mL, QR： 7.06-19.0] than in EPS （57.2 pg/mL, QR： 42.6-73.1, 8.1 pg/mL, QR： 4.2-9.3） and control patients （57.7 pg/mL, QR： 51.2-62.5; 8.1 pg/mL, QR： 5.4-10.3）. A similar relationship was observed for urinary 6-OHMS excretion. Patients with severe PDS symptoms had a higher melatonin concentration than these with moderate syndromes, whereas patients with severe EPS had a lower urinary 6-OHMS excretion than patients with moderate symptoms.CONCLUSION： Evaluation of melatonin serum concentrations and 24-h urinary 6-OHMS excretion are useful methods for differential diagnosis of various clinical forms of FD.展开更多
Objective： To observe the effect of moxibustion therapy plus cupping on perceived exertion and blood biochemical indicators in athletes with exercise-induced fatigue. Methods： A total of 30 gymnasts were randomized ...Objective： To observe the effect of moxibustion therapy plus cupping on perceived exertion and blood biochemical indicators in athletes with exercise-induced fatigue. Methods： A total of 30 gymnasts were randomized into two groups. After intensive physical training, 15 cases in the treatment group were treated by mild moxibustion and cupping, whereas the other 15 cases in the control group took a 30-rain break. After that, the Creatine Kinase （CK）, Blood Urea Nitrogen （BUN）, routine urinalysis, Rating of Perceived Exertion （RPE） and changes in Self-report Symptom Checklist 90 （SCL-90） were observed before and after one and periodic exercises. Results： After intensive physical training, athletes in the treatment group obtained a faster recovery of elevated CK levels than those in the control group. Analysis on the SCL-90 has shown that athletes in the treatment group had better interpersonal relations than those in the control group. Additionally, RPE analysis has also indicated that athletes in the treatment group had milder fatigue than those in the control group. Conclusion： Combined moxibustion with cupping is an effective and easy-to-operate method for exercise-induced fatigue.展开更多
基金Supported by The Ministry of Science and Higher Education of Poland,project NN 402481937
文摘To evaluate blood concentration of melatonin and urinary excretion of its metabolite, 6-sulfatoxymelatonin （6-OHMS）, in functional dyspepsia （FD）. METHODS： Ninety individuals were enrolled in the study： 30 in each study group： patients with postprandial distress syndrome （PDS）, epigastric pain syndrome （EPS）, and controls. Blood samples were drawn at 02：00 and 09：00 h and 24-h urine collection was performed. Serum melatonin and urinary 6-OHMS concentrations were measured by enzyme-linked immunosorbent assay. RESULTS： Serum melatonin concentration at night and in the morning was significantly （P 〈 0.001） higher inPDS patients [at 02：00 h-93.3 pg/mL, quartile range （QR）： 79.8-116.2; at 09.00 h-14.3 pg/mL, QR： 7.06-19.0] than in EPS （57.2 pg/mL, QR： 42.6-73.1, 8.1 pg/mL, QR： 4.2-9.3） and control patients （57.7 pg/mL, QR： 51.2-62.5; 8.1 pg/mL, QR： 5.4-10.3）. A similar relationship was observed for urinary 6-OHMS excretion. Patients with severe PDS symptoms had a higher melatonin concentration than these with moderate syndromes, whereas patients with severe EPS had a lower urinary 6-OHMS excretion than patients with moderate symptoms.CONCLUSION： Evaluation of melatonin serum concentrations and 24-h urinary 6-OHMS excretion are useful methods for differential diagnosis of various clinical forms of FD.
基金supported by Shanghai Sports Bureau(04JT014)Shanghai Leading Academic Discipline Project(S30304)
文摘Objective： To observe the effect of moxibustion therapy plus cupping on perceived exertion and blood biochemical indicators in athletes with exercise-induced fatigue. Methods： A total of 30 gymnasts were randomized into two groups. After intensive physical training, 15 cases in the treatment group were treated by mild moxibustion and cupping, whereas the other 15 cases in the control group took a 30-rain break. After that, the Creatine Kinase （CK）, Blood Urea Nitrogen （BUN）, routine urinalysis, Rating of Perceived Exertion （RPE） and changes in Self-report Symptom Checklist 90 （SCL-90） were observed before and after one and periodic exercises. Results： After intensive physical training, athletes in the treatment group obtained a faster recovery of elevated CK levels than those in the control group. Analysis on the SCL-90 has shown that athletes in the treatment group had better interpersonal relations than those in the control group. Additionally, RPE analysis has also indicated that athletes in the treatment group had milder fatigue than those in the control group. Conclusion： Combined moxibustion with cupping is an effective and easy-to-operate method for exercise-induced fatigue.
