目的探讨尿常规联合普通光学显微镜尿红细胞形态检查在早期发现和诊断Alport综合征（AS）家系中的应用。方法对门诊和住院患儿尿常规检查发现红细胞尿者,在1周内进行1~2次复查,若复查仍为红细胞尿者,取其晨起新鲜尿液10 m L,1 500 r...目的探讨尿常规联合普通光学显微镜尿红细胞形态检查在早期发现和诊断Alport综合征（AS）家系中的应用。方法对门诊和住院患儿尿常规检查发现红细胞尿者,在1周内进行1~2次复查,若复查仍为红细胞尿者,取其晨起新鲜尿液10 m L,1 500 r·min-1离心10 min,弃上清液,光学显微镜下观察尿沉渣红细胞形态。如红细胞为严重变形红细胞,诊断为肾性血尿,对其父母行尿自动分析检查及尿红细胞形态检查,有异常者进行家系调查。结果通过尿常规检查联合普通光学显微镜尿红细胞形态检查,发现7个肾性血尿患儿,经过家系调查初步诊断为X连锁显性遗传AS家系。结论尿常规联合普通光学显微镜尿红细胞形态检查能够早期发现和诊断AS家系,值得在基层医院应用。展开更多
Objective To explore the clinical value of computer-assisted pathologic imaging analysis in evaluating urinary red blood cell morphology. Method 24 nephropathy patients were treated as study group, and 28 patients who...Objective To explore the clinical value of computer-assisted pathologic imaging analysis in evaluating urinary red blood cell morphology. Method 24 nephropathy patients were treated as study group, and 28 patients whose haematuria due to shockwave lithotomy were treated as control. Urine sediment of each patient was stained,and red blood morphology analysis with computer-assisted imaging system was made. Result The sensitivity and specificity were 83.3% and 90.9% respectively in diagnosis of glomerular haematuria; for non-glomerular haematuria,the sensitivity and specificity all were 100%. Conclusion There are high sensitivity and specificity in diagnosis of glomerular haematuria using computer-assisted imaging analysis.It is reliable and has significant clinical value.展开更多
文摘Objective To explore the clinical value of computer-assisted pathologic imaging analysis in evaluating urinary red blood cell morphology. Method 24 nephropathy patients were treated as study group, and 28 patients whose haematuria due to shockwave lithotomy were treated as control. Urine sediment of each patient was stained,and red blood morphology analysis with computer-assisted imaging system was made. Result The sensitivity and specificity were 83.3% and 90.9% respectively in diagnosis of glomerular haematuria; for non-glomerular haematuria,the sensitivity and specificity all were 100%. Conclusion There are high sensitivity and specificity in diagnosis of glomerular haematuria using computer-assisted imaging analysis.It is reliable and has significant clinical value.
