Miehel教授,为法国巴黎第五大学Necker 医院放射科主任,法国放射学杂志(Journal de Radiologue)首席责任编辑。是法国知名的放射学专家,尤其对泌尿放射学有较深的造诣,他曾三次访问中国,对我国怀有十分友好的感情,他专为我国同道撰写了...Miehel教授,为法国巴黎第五大学Necker 医院放射科主任,法国放射学杂志(Journal de Radiologue)首席责任编辑。是法国知名的放射学专家,尤其对泌尿放射学有较深的造诣,他曾三次访问中国,对我国怀有十分友好的感情,他专为我国同道撰写了三篇有关泌尿系造影的论文,特投本刊。本文是其中的一篇(另两篇将陆续发表),供同道们参考。展开更多
AIM： To evaluate whether urokinase perfusion of non-heart-beating cadaveric donor livers reduces the incidence of intrahepatic ischemic-type biliary lesions （IITBLs）. METHODS： A prospective study was conducted to ...AIM： To evaluate whether urokinase perfusion of non-heart-beating cadaveric donor livers reduces the incidence of intrahepatic ischemic-type biliary lesions （IITBLs）. METHODS： A prospective study was conducted to investigate potential microthrombosis in biliary microcirculation when non-heart-beating cadaveric livers were under warm or cold ischemic conditions. The experimental group included 140 patients who underwent liver transplantation during the period of January 2006 to December 2007, and survived for more than 1 year. The control group included 220 patients who received liver transplantation between July 1999 and December 2005 and survived for more than 1 year. In the experimental group, the arterial system of the donor liver was perfused twice with urokinase during cold perfusion and after trimming of the donor liver. The incidence of IITBLs was compared between the two groups. RESULTS： In the control group, the incidence of IITBLs was 5.9% （13/220 cases） after 3-11 mo of transplantation. In the experimental group, two recipients （1.4%） developed IITBLs at 3 and 6 mo after transplantation, respectively. The difference in the incidence between the two groups was statistically significant （P 〈 0.05）. CONCLUSION： Double from non-heart-beating perfusion of cadaveric livers donors with urokinase may reduce the incidence of IITBLs.展开更多
文摘Miehel教授,为法国巴黎第五大学Necker 医院放射科主任,法国放射学杂志(Journal de Radiologue)首席责任编辑。是法国知名的放射学专家,尤其对泌尿放射学有较深的造诣,他曾三次访问中国,对我国怀有十分友好的感情,他专为我国同道撰写了三篇有关泌尿系造影的论文,特投本刊。本文是其中的一篇(另两篇将陆续发表),供同道们参考。
文摘AIM： To evaluate whether urokinase perfusion of non-heart-beating cadaveric donor livers reduces the incidence of intrahepatic ischemic-type biliary lesions （IITBLs）. METHODS： A prospective study was conducted to investigate potential microthrombosis in biliary microcirculation when non-heart-beating cadaveric livers were under warm or cold ischemic conditions. The experimental group included 140 patients who underwent liver transplantation during the period of January 2006 to December 2007, and survived for more than 1 year. The control group included 220 patients who received liver transplantation between July 1999 and December 2005 and survived for more than 1 year. In the experimental group, the arterial system of the donor liver was perfused twice with urokinase during cold perfusion and after trimming of the donor liver. The incidence of IITBLs was compared between the two groups. RESULTS： In the control group, the incidence of IITBLs was 5.9% （13/220 cases） after 3-11 mo of transplantation. In the experimental group, two recipients （1.4%） developed IITBLs at 3 and 6 mo after transplantation, respectively. The difference in the incidence between the two groups was statistically significant （P 〈 0.05）. CONCLUSION： Double from non-heart-beating perfusion of cadaveric livers donors with urokinase may reduce the incidence of IITBLs.
