The mangrove plant Heritiera littoralis D. (Sterculi-aceae) is widelydistributed in southeastern Asia and traditionally used as a fish, arrowhead, and spearhead poison .It has also been used as a folk medicine to trea...The mangrove plant Heritiera littoralis D. (Sterculi-aceae) is widelydistributed in southeastern Asia and traditionally used as a fish, arrowhead, and spearhead poison .It has also been used as a folk medicine to treat he-maturia and diarrhea for a long history inChina . Past investigations on the chemical constituents of this plant have yielded fourtriterpenes, five sesquiterpenes, a phe-nylproanoid-glycerol and four flavonoids. In the presentstudy, eight flavonoids were isolated from the 95% EtOH extract of the leaves of this plant, andidentified as quercitrin (1), quercetin (2),kaempferol-3-O-(6″-O-E-p-coumaroyl)-β-D-glucopyranoside ( 3 ), kaempferol (4), kaempferitrin (5),myricetin (6), eriodictyol (7), and catechin (8) on the basis of their spectral data.展开更多
A new fluorescence silver nanosensor assisted by surfactant has been recently synthesized and applied to ultra trace nickel determination. The methodology was validated by the standard addition method and satisfactori...A new fluorescence silver nanosensor assisted by surfactant has been recently synthesized and applied to ultra trace nickel determination. The methodology was validated by the standard addition method and satisfactorily applied to nickel determination in urine without previous treatment, coming from subjects with different smoking addiction levels and second hand smokers. Within-day precision was better than 0.011 CV. The reproducibility （between-days precision） was also evaluated over 3 days by performing six determinations each day with a CV of 0.025. The proposed methodology represents a promising approach in the area of biological monitoring due to its low operation cost, simplicity of instrumentation, high sampling speed and non-polluting solvents. Obtained results of urinary nickel concentration were successfully correlated with the tobacco addiction.展开更多
OBJECTIVE: To assess the efficacy of Huangshukuihua(Flos Abelmoschi Manihot) on diabetic nephropathy(DN).METHODS: Articles were retrieved from Pub Med,EMBASE, the Cochrane Central Register of Controlled Trials, Web of...OBJECTIVE: To assess the efficacy of Huangshukuihua(Flos Abelmoschi Manihot) on diabetic nephropathy(DN).METHODS: Articles were retrieved from Pub Med,EMBASE, the Cochrane Central Register of Controlled Trials, Web of Science, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure Database, Chinese Evidence-Based Medicine Database, and Wanfang Database. Two reviewers independently reviewed the article. Only randomized controlled trials were included and 27 were identified involving 2239 patients(1143 in the treatment group and 1096 in the control group).RESULTS: Huangshukuihua(Flos Abelmoschi Manihot) had a significant effect on renal function by improving blood urea nitrogen and serum creatinine,reducing urine protein(24-h urine protein, and urinary albumin excretion rate), and improving serum albumin level, compared with the control group.CONCLUSION: Our findings suggest that, although the bioactive ingredients and mechanism underlying renal protection are unknown, the role of Huangshukuihua(Flos Abelmoschi Manihot) in the treatment of DN deserves further investigation.展开更多
文摘The mangrove plant Heritiera littoralis D. (Sterculi-aceae) is widelydistributed in southeastern Asia and traditionally used as a fish, arrowhead, and spearhead poison .It has also been used as a folk medicine to treat he-maturia and diarrhea for a long history inChina . Past investigations on the chemical constituents of this plant have yielded fourtriterpenes, five sesquiterpenes, a phe-nylproanoid-glycerol and four flavonoids. In the presentstudy, eight flavonoids were isolated from the 95% EtOH extract of the leaves of this plant, andidentified as quercitrin (1), quercetin (2),kaempferol-3-O-(6″-O-E-p-coumaroyl)-β-D-glucopyranoside ( 3 ), kaempferol (4), kaempferitrin (5),myricetin (6), eriodictyol (7), and catechin (8) on the basis of their spectral data.
文摘A new fluorescence silver nanosensor assisted by surfactant has been recently synthesized and applied to ultra trace nickel determination. The methodology was validated by the standard addition method and satisfactorily applied to nickel determination in urine without previous treatment, coming from subjects with different smoking addiction levels and second hand smokers. Within-day precision was better than 0.011 CV. The reproducibility （between-days precision） was also evaluated over 3 days by performing six determinations each day with a CV of 0.025. The proposed methodology represents a promising approach in the area of biological monitoring due to its low operation cost, simplicity of instrumentation, high sampling speed and non-polluting solvents. Obtained results of urinary nickel concentration were successfully correlated with the tobacco addiction.
基金Supported by Sichuan Province Science and Technology Support Program:the Discussion of Pathogenesis and Treatment of Type 2 Diabetes and Its Chronic Complications(No.2014SZ0020)
文摘OBJECTIVE: To assess the efficacy of Huangshukuihua(Flos Abelmoschi Manihot) on diabetic nephropathy(DN).METHODS: Articles were retrieved from Pub Med,EMBASE, the Cochrane Central Register of Controlled Trials, Web of Science, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure Database, Chinese Evidence-Based Medicine Database, and Wanfang Database. Two reviewers independently reviewed the article. Only randomized controlled trials were included and 27 were identified involving 2239 patients(1143 in the treatment group and 1096 in the control group).RESULTS: Huangshukuihua(Flos Abelmoschi Manihot) had a significant effect on renal function by improving blood urea nitrogen and serum creatinine,reducing urine protein(24-h urine protein, and urinary albumin excretion rate), and improving serum albumin level, compared with the control group.CONCLUSION: Our findings suggest that, although the bioactive ingredients and mechanism underlying renal protection are unknown, the role of Huangshukuihua(Flos Abelmoschi Manihot) in the treatment of DN deserves further investigation.
