The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological met...The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rbl into ginsenoside C-K by snailases. The optimum conditions were as follows: pH 5,12, temperature 51 ℃, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol· L- 1 ferric ion was found to significantly improve the enzymolysis ofsnailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside C- K production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application.展开更多
Due to the extremely arid climate in the western Qaidam Basin,the groundwater almost becomes the single water source for local residents and industrial production.It is necessary to know the reliable information on th...Due to the extremely arid climate in the western Qaidam Basin,the groundwater almost becomes the single water source for local residents and industrial production.It is necessary to know the reliable information on the groundwater cycle in this region for reasonable and sustainable exploitation of the groundwater resources with the further execution of recycling economy policies.This study focused on the recharge,the flow rate and the discharge of groundwater in the western Qaidam Basin through investigations on water chemistry and isotopes.Hydrological,chemical and isotopic characteristics show that the groundwater in the western Qaidam Basin was recharged by meltwater from new surface snow and old bottom glaciers on the northern slope of the Kunlun Mountains.In addition,the results also prove that the source water is enough and stable,and the rates of the circulation and renewal of the groundwater are relatively quick.Therefore,it can be concluded that the groundwater resources would guarantee the regional requirement if the meltwater volume of the mountains has not a great changes in future,moreover,water exploitation should be limited to the renewable amount of the groundwater reservoir in the western Qaidam Basin.展开更多
Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and respo...Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and responding to global environmental change. Aiming at a thorough examination of the implementation of ITGP in China, this paper presents its objectives, its three major areas, and their progress so far. It also identifies the key elements of its management and proposes new perspectives on managing green transformation. For instance, we introduce a case study on cement industry that shows the positive policy effects of reducing backward production capacity on PCDD/Fs emissions. Finally,to develop different transformation scenarios for a green future, we propose four strategies: 1) policy integration for promoting green industry, 2)system innovation and a multidisciplinary approach, 3) collaborative governance with all potential stakeholders, and 4) managing uncertainty,risks, and long-time horizons.展开更多
Based on the coal demand under the 1.5 ℃ scenario, the amount of coal production in China was estimated in this study. According to the mutual relationship between the factors influencing coal production, an economet...Based on the coal demand under the 1.5 ℃ scenario, the amount of coal production in China was estimated in this study. According to the mutual relationship between the factors influencing coal production, an econometric model was constructed based on simultaneous equations, and the synergistic effect of each factor on the coal industry was estimated under the 1.5 ℃ scenario. Then, predictions were respectively made in the five aspects: coal production, coal science and technology progress, employment number, safe production level, and occupational health level, in different scenarios from 2016 to 2050. The results showed that before 2040, the comprehensive negative effect of the 1.5 ℃ situation is more than or equals to the positive effect. The 1.5 ℃ scenario has the biggest negative impact on employment, whose solution should be the focus. By 2050, the positive effects of the 1.5℃ scenario exceed the negative effect because of the enhancement in technical level and in the attention given to the whole production. Safety is improved, and health defects decline and the most obvious positive effect is on the ecological environment. The decrease of coal production will reduce the ecological environmental damage and significantly improve the ecological environment. In general, the prediction of 1.5 ℃ scenario promotes the increase of scientific production capacity and promotes the orderly development of coal. It has strengthened the safety and health protection degree, made the coal industry more efficient and competitive, and avoided or reduced the impact of coal development on the ecological environment and achieved environmental friendliness. However, the 1.5 ℃ situation also increases the employment pressure of the society, which affects the economic development of the major coal producing areas, but the situation can be overcome through the transformation and upgrading of the region. Finally, the impacts of various factors under the 1.5 ℃ scenario were evaluated through a unified comparison of the synergistic effect monetization using the cost and payment willingness methods. Based on the research results, suggestions on the regulation of coal production were proposed relating to resettlement of workers, protection of the ecological environment, and improvement of workers' health.展开更多
This paper presents an advanced method for system identification of industrial processes with big time delays. Identification methods based on neural networks, tree partitioning and wavelet networks are presented and ...This paper presents an advanced method for system identification of industrial processes with big time delays. Identification methods based on neural networks, tree partitioning and wavelet networks are presented and analyzed. The obtained results are compared and the tree partitioning method is selected as most appropriate identification method for the water treatment process. The decision was made based on a thorough analysis on the overall fit between the measured data and the results of the simulated model. At the end, we propose possibilities for further research in this area.展开更多
Economic globalization has promoted the formation of global production network, and correspondingly the high-quality environmental factors are reconfigured behind the physical commodities exchange. Export trade not on...Economic globalization has promoted the formation of global production network, and correspondingly the high-quality environmental factors are reconfigured behind the physical commodities exchange. Export trade not only drives China's economic growth, promotes industrial upgrading and technological progress, but also may have a negative impact on the environment. After reviewing and summarizing the existing relevant literatures, tire paper collects the required statistic data from 2003 to 2006 and uses the panel data model to measure the environmental effects of export trade in the Yangtze River Delta. The results show that the export trade of Yangtze River Delta has a negative impact on the environment. When the variables of economic scale, economic structure areftxed, with the export trade growth of 1%, the industrial sulfur dioxide emission and industrial waste water emtsston will increase by 0.12% and 0.23% respectively. So we must pay serious attention to the negative effects, and promote regional sustainable development rapidly through adjusting the export structure and strengthening environmental regulations.展开更多
An ever more demanding consumer market and the need for companies to be more competitive have led organizations to try to eliminate waste. This research is a case study which presents a proposal for intervention in or...An ever more demanding consumer market and the need for companies to be more competitive have led organizations to try to eliminate waste. This research is a case study which presents a proposal for intervention in order to improve performance of a pre-cast concrete block factory in outer Goihnia. As a first step, waste in the production process was identified through analysis of data on time involved in each step of the process. Then, applying the concepts of lean production, a list of activities was drawn up with a view to eliminating non-value-added work, identifying waste, decreasing cycle time, streamlining the production process and increasing the flexibility and transparency of the process. From the results, it was possible to identify the sources of waste and provide management with information for strategic decisions about production. Finally, various suggestions were made with a view to eliminating or mitigating bottlenecks in the production process.展开更多
基金Supported by the National Natural Science Foundation of China(21476182,21776227,21776228)Shaanxi Key Laboratory of Degradable Biomedical Materials Program(2014SZS07-K04,2014SZS07-P05,15JS106,2014SZS07-Z01,2014SZS07-Z02,2016SZSj-35,2014SZS07-K03)Shaanxi R&D Center of Biomaterials and Fermentation Engineering Program(2015HBGC-04)
文摘The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rbl into ginsenoside C-K by snailases. The optimum conditions were as follows: pH 5,12, temperature 51 ℃, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol· L- 1 ferric ion was found to significantly improve the enzymolysis ofsnailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside C- K production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application.
基金Under the auspices of National Natural Science Foundation of China (No 40603007)
文摘Due to the extremely arid climate in the western Qaidam Basin,the groundwater almost becomes the single water source for local residents and industrial production.It is necessary to know the reliable information on the groundwater cycle in this region for reasonable and sustainable exploitation of the groundwater resources with the further execution of recycling economy policies.This study focused on the recharge,the flow rate and the discharge of groundwater in the western Qaidam Basin through investigations on water chemistry and isotopes.Hydrological,chemical and isotopic characteristics show that the groundwater in the western Qaidam Basin was recharged by meltwater from new surface snow and old bottom glaciers on the northern slope of the Kunlun Mountains.In addition,the results also prove that the source water is enough and stable,and the rates of the circulation and renewal of the groundwater are relatively quick.Therefore,it can be concluded that the groundwater resources would guarantee the regional requirement if the meltwater volume of the mountains has not a great changes in future,moreover,water exploitation should be limited to the renewable amount of the groundwater reservoir in the western Qaidam Basin.
基金funded by the Chinese Academy of Sciences (KZZD-EW-TZ-12)National Natural Science Foundation of China (414201040045 and 41371488)Natural Science Foundation of Hainan Province (413129)
文摘Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and responding to global environmental change. Aiming at a thorough examination of the implementation of ITGP in China, this paper presents its objectives, its three major areas, and their progress so far. It also identifies the key elements of its management and proposes new perspectives on managing green transformation. For instance, we introduce a case study on cement industry that shows the positive policy effects of reducing backward production capacity on PCDD/Fs emissions. Finally,to develop different transformation scenarios for a green future, we propose four strategies: 1) policy integration for promoting green industry, 2)system innovation and a multidisciplinary approach, 3) collaborative governance with all potential stakeholders, and 4) managing uncertainty,risks, and long-time horizons.
文摘Based on the coal demand under the 1.5 ℃ scenario, the amount of coal production in China was estimated in this study. According to the mutual relationship between the factors influencing coal production, an econometric model was constructed based on simultaneous equations, and the synergistic effect of each factor on the coal industry was estimated under the 1.5 ℃ scenario. Then, predictions were respectively made in the five aspects: coal production, coal science and technology progress, employment number, safe production level, and occupational health level, in different scenarios from 2016 to 2050. The results showed that before 2040, the comprehensive negative effect of the 1.5 ℃ situation is more than or equals to the positive effect. The 1.5 ℃ scenario has the biggest negative impact on employment, whose solution should be the focus. By 2050, the positive effects of the 1.5℃ scenario exceed the negative effect because of the enhancement in technical level and in the attention given to the whole production. Safety is improved, and health defects decline and the most obvious positive effect is on the ecological environment. The decrease of coal production will reduce the ecological environmental damage and significantly improve the ecological environment. In general, the prediction of 1.5 ℃ scenario promotes the increase of scientific production capacity and promotes the orderly development of coal. It has strengthened the safety and health protection degree, made the coal industry more efficient and competitive, and avoided or reduced the impact of coal development on the ecological environment and achieved environmental friendliness. However, the 1.5 ℃ situation also increases the employment pressure of the society, which affects the economic development of the major coal producing areas, but the situation can be overcome through the transformation and upgrading of the region. Finally, the impacts of various factors under the 1.5 ℃ scenario were evaluated through a unified comparison of the synergistic effect monetization using the cost and payment willingness methods. Based on the research results, suggestions on the regulation of coal production were proposed relating to resettlement of workers, protection of the ecological environment, and improvement of workers' health.
文摘This paper presents an advanced method for system identification of industrial processes with big time delays. Identification methods based on neural networks, tree partitioning and wavelet networks are presented and analyzed. The obtained results are compared and the tree partitioning method is selected as most appropriate identification method for the water treatment process. The decision was made based on a thorough analysis on the overall fit between the measured data and the results of the simulated model. At the end, we propose possibilities for further research in this area.
文摘Economic globalization has promoted the formation of global production network, and correspondingly the high-quality environmental factors are reconfigured behind the physical commodities exchange. Export trade not only drives China's economic growth, promotes industrial upgrading and technological progress, but also may have a negative impact on the environment. After reviewing and summarizing the existing relevant literatures, tire paper collects the required statistic data from 2003 to 2006 and uses the panel data model to measure the environmental effects of export trade in the Yangtze River Delta. The results show that the export trade of Yangtze River Delta has a negative impact on the environment. When the variables of economic scale, economic structure areftxed, with the export trade growth of 1%, the industrial sulfur dioxide emission and industrial waste water emtsston will increase by 0.12% and 0.23% respectively. So we must pay serious attention to the negative effects, and promote regional sustainable development rapidly through adjusting the export structure and strengthening environmental regulations.
文摘An ever more demanding consumer market and the need for companies to be more competitive have led organizations to try to eliminate waste. This research is a case study which presents a proposal for intervention in order to improve performance of a pre-cast concrete block factory in outer Goihnia. As a first step, waste in the production process was identified through analysis of data on time involved in each step of the process. Then, applying the concepts of lean production, a list of activities was drawn up with a view to eliminating non-value-added work, identifying waste, decreasing cycle time, streamlining the production process and increasing the flexibility and transparency of the process. From the results, it was possible to identify the sources of waste and provide management with information for strategic decisions about production. Finally, various suggestions were made with a view to eliminating or mitigating bottlenecks in the production process.