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用非入侵差分反射法跟踪肿瘤的充氧演变
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作者 M.Guichard 顾聚兴 《红外》 CAS 1999年第3期19-23,共5页
在固体肿瘤的治疗过程中,缺氧症是一个耐辐射的因素。为了使这种肿瘤敏感辐射,可让病人吸入氧及二氧化碳混合气体(95%O_2-5%CO_2),当肿瘤的充氧因吸入这种混合气体而增加到最高峰时,重要的是对肿瘤进行照射。一种名为DADOT的非侵入式监... 在固体肿瘤的治疗过程中,缺氧症是一个耐辐射的因素。为了使这种肿瘤敏感辐射,可让病人吸入氧及二氧化碳混合气体(95%O_2-5%CO_2),当肿瘤的充氧因吸入这种混合气体而增加到最高峰时,重要的是对肿瘤进行照射。一种名为DADOT的非侵入式监测仪器可以估计肿瘤组织中充氧血红蛋白与脱氧血红蛋白的相对比例。其原理是测量血红蛋白对红光或者红外辐射吸收的变化。发射波长分别为0.66μm和0.94μm的两个电致发光二极管与两根光纤耦合,而光纤的末端则靠近肿瘤。充氧形式和非充氧形式的血红蛋白对这两种波长的吸收是有差异的。向后散射至皮肤表面的光由第三根光纤接收,并由配有放大器的一个光电二极管测量。我们用该仪器跟踪了两个肿瘤系在吸入氧及二氧化碳混合气体过程中肿瘤充氧的变化。我们在一个病人身上也做了这样的试验。初步的结果表明,DADOT是一种可靠的仪器,它能给出可重复的结果,并可日常用于跟踪病人肿瘤的充氧变化。 展开更多
关键词 肿瘤 差分反射法 辐射治疗 充氧演变
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Acoustic field simulations of logging while drilling by cylindrical finite difference with variable grids 被引量:1
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作者 Pan Yue He Xiao +1 位作者 Chen Hao Wang Xiu-Ming 《Applied Geophysics》 SCIE CSCD 2022年第1期11-28,143,共19页
This study proposes an elastic finite difference(FD)time domain method with variable grids in three-dimensional cylindrical coordinates.The calculations will diverge and become less accurate by conventional cylindrica... This study proposes an elastic finite difference(FD)time domain method with variable grids in three-dimensional cylindrical coordinates.The calculations will diverge and become less accurate by conventional cylindrical FD as the grid size gradually becomes more extensive with the increasing radius.To prevent grids from being too coarse in far fields,we compensate for the grid cell infl ation by refi ning the grid step in the azimuthal direction.The variable grid FD in the cylindrical coordinate systems has a higher effi ciency in solving acoustic logging while drilling(LWD)problems because the grid boundaries are consistent with those of the drill collar and the borehole.The proposed algorithm saves approximately 94%of the FD grids,80%of the computation time,and memory with a higher calculation accuracy than the FD on rectangular grids for the same models.We also calculate the acoustic LWD responses of the fl uid-fi lled borehole intersecting with fractures.Refl ections are generated at the fractures,which can be equivalent to an additional scattering source.The mode conversions between the collar and the Stoneley waves are revealed.The Stoneley spectra are more sensitive to the fracture.Finally,the logs in a heterogeneous formation with two refl ectors far from the borehole are modeled,and a means of estimating the azimuth of geological interfaces from refl ections is proposed. 展开更多
关键词 acoustic detection finite difference variable grid method scattering and refl ection cylindrical guided wave
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Effect of selected signals of interest on ultrasonic backscattering measurement in cancellous bones 被引量:12
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作者 LIU ChengCheng HAN HaiJie +1 位作者 TA DeAn WANG WeiQi 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2013年第7期1310-1316,共7页
This study examined how the signals of interest (SOI) effect on the backscattering measurement numerically based on 3-D finite-difference time-domain (FDTD) method. High resolution microstructure mappings of bovin... This study examined how the signals of interest (SOI) effect on the backscattering measurement numerically based on 3-D finite-difference time-domain (FDTD) method. High resolution microstructure mappings of bovine cancellous bones provided by micro-CT were used as the input geometry for simulations. Backscatter coefficient (BSC), integrated backscatter coefficient (IBC) and apparent integrated backscatter (AIB) were calculated with changing the start (L1) and duration (L2) of the SOl. The results demonstrated that BSC and IBC decrease as L1 increases, and AIB decreases more rapidly as L1 increases. The backscattering parameters increase with fluctuations as a function of L2 when L2 is less than 6 mm. However, BSC and IBC change little as L2 continues to increase, while AIB slowly decreases as L2 continues to increase. The results showed how the selections of the SOI effect on the backscattering measurement. An explicit standard for SOl selection was proposed in this study and short L1 (about 1.5 mm) and appropriate L2 (6 mm-12 mm) were recommended for the calculations of backscattering parameters. 展开更多
关键词 ultrasonic backscattering cancellous bone FDTD simulation signals of interest backscattering parameters
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