粉煤瓦斯解吸实验是研究粉煤瓦斯解吸动力学特征的常用手段之一,其结果是揭示粉煤放散瓦斯能力的重要参数。传统实验方法在煤样罐泄压后开始测量瓦斯解吸数据,存在较大误差。利用甲烷与氦气的粉煤吸附特性差异性提出了改进的粉煤瓦斯解...粉煤瓦斯解吸实验是研究粉煤瓦斯解吸动力学特征的常用手段之一,其结果是揭示粉煤放散瓦斯能力的重要参数。传统实验方法在煤样罐泄压后开始测量瓦斯解吸数据,存在较大误差。利用甲烷与氦气的粉煤吸附特性差异性提出了改进的粉煤瓦斯解吸实验方法,并建立了初始瓦斯粉煤快速解吸模型,从而揭示了煤体粉化后瓦斯快速解吸的内在机制。研究结果表明:解吸开始的前5 s,0.075~0.150 mm JG71煤样解吸的瓦斯量是1.00~2.36 mm煤样的2.05倍,而0.075~0.150 mm JG82煤样解析的瓦斯量是1.00~2.30煤样的10.29倍;煤样粉化程度越高,吸附平衡压力越大,初始瓦斯解吸速度越大,传统实验方法得到的数据误差越大。研究结果为突出粉化煤体快速解吸瓦斯、提供瓦斯膨胀能、促进煤与瓦斯突出传播的研究提供了数据支撑,同时为完善煤与瓦斯致灾机理奠定基础。展开更多
OBJECTIVE： To explore the nature of ＂Yin internal heat caused by Yin-deficiency＂ in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome a...OBJECTIVE： To explore the nature of ＂Yin internal heat caused by Yin-deficiency＂ in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome and analyzing the gene expression pro- file of their livers. METHODS： A Yin-deficiency-heat syndrome model was induced in rats using three Chinese medicinal herbs. Glycogen and triglycerides in blood plasma, and the enzyme activity of ATP in livers were mea- sured colorimetrically. Triiodothyronine （T3）, thyrox- ine （T4）, and thyroid stimulating hormone levels in blood plasma were also measured with enzyme linked immunosorbent assay. The gene expression profile of livers was detected with gene chip analy- sis. Differentially expressed genes were screened out and classified according to Gene Ontology. The accuracy of results were examined with reversetranscription-polymerase chain reaction RESULTS： Compared with the control group, body weight （P〈0.05） and hepatic glycogen （P〈0.05） were significantly lower in the Yin-deficiency-heat syndrome group. Moreover, toe temperature （P〈 0.01） and triglyceride （P〈0.05）, Na ＋-K＋-ATPase （P〈 0.01）, Mg2＋-ATPase （P〈0.01）, T3 （P〈0.05）, and 1-4 （P〈 0.01） levels were significantly higher. There were 99 differentially expressed genes in livers from the Y/n-deficiency-heat syndrome group. Genes were mainly related to sterol synthesis （Pc=0.0392）, de- fense response （Pc=0.0448）, and sterol metabolism （Pc=0.0533）. CONCLUSION： Abnormal expression genes in rats with Yin-deficiency-heat syndrome prompted the synthesis and metabolism of cholesterol, increased energy consumption, and reduced defense re- sponse. This gene expression might be the molecu- lar mechanism underlying ＂internal heat caused by Yin-deficiency＂ in the rats with Yin-deficiency-heat syndrome.展开更多
文摘粉煤瓦斯解吸实验是研究粉煤瓦斯解吸动力学特征的常用手段之一,其结果是揭示粉煤放散瓦斯能力的重要参数。传统实验方法在煤样罐泄压后开始测量瓦斯解吸数据,存在较大误差。利用甲烷与氦气的粉煤吸附特性差异性提出了改进的粉煤瓦斯解吸实验方法,并建立了初始瓦斯粉煤快速解吸模型,从而揭示了煤体粉化后瓦斯快速解吸的内在机制。研究结果表明:解吸开始的前5 s,0.075~0.150 mm JG71煤样解吸的瓦斯量是1.00~2.36 mm煤样的2.05倍,而0.075~0.150 mm JG82煤样解析的瓦斯量是1.00~2.30煤样的10.29倍;煤样粉化程度越高,吸附平衡压力越大,初始瓦斯解吸速度越大,传统实验方法得到的数据误差越大。研究结果为突出粉化煤体快速解吸瓦斯、提供瓦斯膨胀能、促进煤与瓦斯突出传播的研究提供了数据支撑,同时为完善煤与瓦斯致灾机理奠定基础。
基金Supported by the National Basic Research Program of China(973 Program,No.2007CB512601,2013CB531803)
文摘OBJECTIVE： To explore the nature of ＂Yin internal heat caused by Yin-deficiency＂ in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome and analyzing the gene expression pro- file of their livers. METHODS： A Yin-deficiency-heat syndrome model was induced in rats using three Chinese medicinal herbs. Glycogen and triglycerides in blood plasma, and the enzyme activity of ATP in livers were mea- sured colorimetrically. Triiodothyronine （T3）, thyrox- ine （T4）, and thyroid stimulating hormone levels in blood plasma were also measured with enzyme linked immunosorbent assay. The gene expression profile of livers was detected with gene chip analy- sis. Differentially expressed genes were screened out and classified according to Gene Ontology. The accuracy of results were examined with reversetranscription-polymerase chain reaction RESULTS： Compared with the control group, body weight （P〈0.05） and hepatic glycogen （P〈0.05） were significantly lower in the Yin-deficiency-heat syndrome group. Moreover, toe temperature （P〈 0.01） and triglyceride （P〈0.05）, Na ＋-K＋-ATPase （P〈 0.01）, Mg2＋-ATPase （P〈0.01）, T3 （P〈0.05）, and 1-4 （P〈 0.01） levels were significantly higher. There were 99 differentially expressed genes in livers from the Y/n-deficiency-heat syndrome group. Genes were mainly related to sterol synthesis （Pc=0.0392）, de- fense response （Pc=0.0448）, and sterol metabolism （Pc=0.0533）. CONCLUSION： Abnormal expression genes in rats with Yin-deficiency-heat syndrome prompted the synthesis and metabolism of cholesterol, increased energy consumption, and reduced defense re- sponse. This gene expression might be the molecu- lar mechanism underlying ＂internal heat caused by Yin-deficiency＂ in the rats with Yin-deficiency-heat syndrome.
